Systemic markers of adaptive and innate immunity are associated with chronic obstructive pulmonary disease severity and spirometric disease progression

American Journal of Respiratory Cell and Molecular Biology

Volumn 58, Issue 4, 2018, Pages 500-509

  Halper Stromberg, Eitan ^a,b   Yun, Jeong H ^c   Parker, Margaret M ^c   Singer, Ruth Tal ^d   Gaggar, Amit ^e   Silverman, Edwin K ^c   Leach, Sonia ^b   Bowler, Russell P ^a,b   Castaldi, Peter J ^c  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d GLAXOSMITHKLINE   (United States)

^e University of Alabama at Birmingham   (United States)

Author keywords

Chronic obstructive pulmonary disease; Computational biology; Gene expression; Immunology

Indexed keywords

BIOLOGICAL MARKER; STEROID; TRANSCRIPTOME;

ADAPTIVE IMMUNITY; ADULT; AGED; B LYMPHOCYTE; BASOPHIL; BLOOD CELL COUNT; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL SUBPOPULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; EDITORIAL; EOSINOPHIL COUNT; FEMALE; FORCED EXPIRATORY VOLUME; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOPHENOTYPING; INNATE IMMUNITY; LUNG FUNCTION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEMORY T LYMPHOCYTE; MONOCYTE COUNT; NEUTROPHIL; PREDICTIVE VALUE; PROSPECTIVE STUDY; SMOKING; SPIROMETRY; BLOOD; GENE EXPRESSION PROFILING; IMMUNOLOGY; LEUKOCYTE; LEUKOCYTE COUNT; LUNG; MIDDLE AGED; PATHOPHYSIOLOGY; PHENOTYPE; PROGNOSIS; SEVERITY OF ILLNESS INDEX; TIME FACTOR;

ADAPTIVE IMMUNITY; ADULT; AGED; DISEASE PROGRESSION; FEMALE; FORCED EXPIRATORY VOLUME; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, INNATE; LEUKOCYTE COUNT; LEUKOCYTES; LUNG; MALE; MIDDLE AGED; PHENOTYPE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SEVERITY OF ILLNESS INDEX; SMOKING; SPIROMETRY; TIME FACTORS; TRANSCRIPTOME;

EID: 85045190175     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2017-0373OC     Document Type: Editorial

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