Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease

BMC Immunology

Volumn 14, Issue 1, 2013, Pages

  Vaguliene, Neringa ^a   Zemaitis, Marius ^a   Lavinskiene, Simona ^a   Miliauskas, Skaidrius ^a   Sakalauskas, Raimundas ^a  

^a LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

Author keywords

Chronic obstructive pulmonary disease; Lung cancer; Neutrophils; Reactive oxygen species

Indexed keywords

ADULT; AGED; ARTICLE; CELL COUNT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; IN VITRO STUDY; INFLAMMATION; LARGE CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; LYMPHOCYTE; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NEUTROPHIL; NEUTROPHIL COUNT; SMOKING; SQUAMOUS CELL CARCINOMA;

AGED; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; CELL COUNT; FEMALE; HUMANS; INFLAMMATION; LEUKOCYTE ELASTASE; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; NEUTROPHILS; PEROXIDASE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REACTIVE OXYGEN SPECIES; TETRADECANOYLPHORBOL ACETATE;

EID: 84880976029     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-14-36     Document Type: Article

References (41)

1. Pharoah PD, Dunning AM, Ponder BA, Easton DF. Association studies for finding cancer-susceptibility genetic variants. Nat Rev Cancer 2004, 4(11):850-860. 10.1038/nrc1476, 15516958.
2. Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008, 454(7203):436-444. 10.1038/nature07205, 18650914.
3. Barbu C, Iordache M, Man MG. Inflammation in COPD: pathogenesis, local and systemic effects. Rom J Morphol Embryo 2011, 52(1):21-27.
4. Rahman I. The role of oxidative stress in the pathogenesis of COPD: implications for therapy. Treatments Resp Med 2005, 4(3):175-200.
5. Klaunig JE, Wang Z, Pu X, Zhou S. Oxidative stress and oxidative damage in chemical carcinogenesis. Toxicol Appl Pharm 2011, 254(2):86-99.
6. Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC. Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli. Am J Resp Cell Mol 2006, 35(2):165-174.
7. Tkacova R, Kluchova Z, Joppa P, Petrasova D, Molcanyiova A. Systemic inflammation and systemic oxidative stress in patients with acute exacerbations of COPD. Resp Med 2007, 101(8):1670-1676.
8. Vassallo R, Kroening PR, Parambil J, Kita H. Nicotine and oxidative cigarette smoke constituents induce immune-modulatory and pro-inflammatory dendritic cell responses. Mol Immunol 2008, 45(12):3321-3329. 10.1016/j.molimm.2008.04.014, 2857673, 18533267.
9. Pham CT. Neutrophil serine proteases: specific regulators of inflammation. Nat Rev Immunol 2006, 6(7):541-550. 10.1038/nri1841, 16799473.
10. Andelid K, Bake B, Rak S, Linden A, Rosengren A, Ekberg-Jansson A. Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms. Resp Med 2007, 101(5):888-895.
11. Houghton AM, Rzymkiewicz DM, Ji H, Gregory AD, Egea EE, Metz HE, Stolz DB, Land SR, Marconcini LA, Kliment CR, et al. Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth. Nat Med 2010, 16(2):219-223. 10.1038/nm.2084, 2821801, 20081861.
12. Kossodo S, Zhang J, Groves K, Cuneo GJ, Handy E, Morin J, Delaney J, Yared W, Rajopadhye M, Peterson JD. Noninvasive in vivo quantification of neutrophil elastase activity in acute experimental mouse lung injury. Int J Mol imaging 2011, 2011:581406. 3175392, 21941648.
13. Kuwahara I, Lillehoj EP, Lu W, Singh IS, Isohama Y, Miyata T, Kim KC. Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-{kappa}B activation via EGFR transactivation in a lung epithelial cell line. Am J Physiol-Lung C 2006, 291(3):L407-416.
14. Larsson S, Nordenson A, Glader P, Yoshihara S, Linden A, Slinde F. A gender difference in circulating neutrophils in malnourished patients with COPD. Int J Chron Obs Pulmon Dis 2011, 6:83-88.
15. Chevrier I, Stucker I, Houllier AM, Cenee S, Beaune P, Laurent-Puig P, Loriot MA. Myeloperoxidase: new polymorphisms and relation with lung cancer risk. Pharmacogenetics 2003, 13(12):729-739. 10.1097/00008571-200312000-00004, 14646692.
16. Babusyte A, Stravinskaite K, Jeroch J, Lotvall J, Sakalauskas R, Sitkauskiene B. Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD. Respir Res 2007, 8:81. 10.1186/1465-9921-8-81, 2200652, 18001475.
17. Young RP, Hopkins RJ, Christmas T, Black PN, Metcalf P, Gamble GD. COPD prevalence is increased in lung cancer, independent of age, sex and smoking history. Eur Respir J 2009, 34(2):380-386. 10.1183/09031936.00144208, 19196816.
18. Teramukai S, Kitano T, Kishida Y, Kawahara M, Kubota K, Komuta K, Minato K, Mio T, Fujita Y, Yonei T, et al. Pretreatment neutrophil count as an independent prognostic factor in advanced non-small-cell lung cancer: an analysis of Japan Multinational Trial Organisation LC00-03. Eur J Cancer 2009, 45(11):1950-1958. 10.1016/j.ejca.2009.01.023, 19231158.
19. Oudijk EJ, Nijhuis EH, Zwank MD, Van den Graaf EA, Mager HJ, Coffer PJ, Lammers JW, Koenderman L. Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils. Thorax 2005, 60(7):538-544. 10.1136/thx.2004.034009, 1747456, 15994259.
20. Imtiaz F, Shafique K, Mirza SS, Ayoob Z, Vart P, Rao S. Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population. Int Arch Med 2012, 5(1):2. 10.1186/1755-7682-5-2, 3277482, 22281066.
21. Tibaldi C, Vasile E, Bernardini I, Orlandini C, Andreuccetti M, Falcone A. Baseline elevated leukocyte count in peripheral blood is associated with poor survival in patients with advanced non-small cell lung cancer: a prognostic model. J Cancer Res Clin 2008, 134(10):1143-1149.
22. Wang S, Zhang Z, Fang F, Gao X, Sun W, Liu H. The neutrophil/lymphocyte ratio is an independent prognostic indicator in patients with bone metastasis. Oncology letters 2011, 2(4):735-740. 3406337, 22848258.
23. Sarraf KM, Belcher E, Raevsky E, Nicholson AG, Goldstraw P, Lim E. Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. J Thorac Cardiov Sur 2009, 137(2):425-428.
24. Cedres S, Torrejon D, Martinez A, Martinez P, Navarro A, Zamora E, Mulet-Margalef N, Felip E. Neutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancer. Clin Transl Oncol 2012, 14(11):864-869. 10.1007/s12094-012-0872-5, 22855161.
25. MacNee W, Wiggs B, Belzberg AS, Hogg JC. The effect of cigarette smoking on neutrophil kinetics in human lungs. New Engl J Med 1989, 321(14):924-928. 10.1056/NEJM198910053211402, 2779614.
26. Van Eeden SF, Lawrence E, Sato Y, Kitagawa Y, Hogg JC. Neutrophils released from the bone marrow by granulocyte colony-stimulating factor sequester in lung microvessels but are slow to migrate. Eur Respir J 2000, 15(6):1079-1086. 10.1034/j.1399-3003.2000.01516.x, 10885427.
27. Kowanetz M, Wu X, Lee J, Tan M, Hagenbeek T, Qu X, Yu L, Ross J, Korsisaari N, Cao T, et al. Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G + Ly6C + granulocytes. Proc Natl Acad Sci USA 2010, 107(50):21248-21255. 10.1073/pnas.1015855107, 3003076, 21081700.
28. Domagala-Kulawik J, Guzman J, Costabel U. Immune cells in bronchoalveolar lavage in peripheral lung cancer-analysis of 140 cases. Respiration 2003, 70(1):43-48. 10.1159/000068414, 12584390.
29. Bellocq A, Antoine M, Flahault A, Philippe C, Crestani B, Bernaudin JF, Mayaud C, Milleron B, Baud L, Cadranel J. Neutrophil alveolitis in bronchioloalveolar carcinoma: induction by tumor-derived interleukin-8 and relation to clinical outcome. Am J Pathol 1998, 152(1):83-92. 1858104, 9422526.
30. Dai F, Liu L, Che G, Yu N, Pu Q, Zhang S, Ma J, Ma L, You Z. The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer. BMC cancer 2010, 10:220. 10.1186/1471-2407-10-220, 2880994, 20487543.
31. Zhang BC, Gao J, Wang J, Rao ZG, Wang BC, Gao JF. Tumor-associated macrophages infiltration is associated with peritumoral lymphangiogenesis and poor prognosis in lung adenocarcinoma. Med Oncol 2011, 28(4):1447-1452. 10.1007/s12032-010-9638-5, 20676804.
32. Chu H, Wang M, Gu D, Wu D, Zhang Z, Tang J. The MPO -463G > A polymorphism and cancer risk: a meta-analysis based on 43 case-control studies. Mutagenesis 2010, 25(4):389-395. 10.1093/mutage/geq018, 20418356.
33. Cohen AB, Chenoweth DE, Hugli TE. The release of elastase, myeloperoxidase, and lysozyme from human alveolar macrophages. Am Rev Respir Dis 1982, 126(2):241-247.
34. Heijink IH, Brandenburg SM, Noordhoek JA, Slebos DJ, Postma DS, Van Oosterhout AJ. Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD. Resp Res 2011, 12:110.
35. Carpagnano GE, Spanevello A, Palladino GP, Gramiccioni C, Ruggieri C, Carpagnano F, Foschino Barbaro MP. Cigarette smoke and increased COX-2 and survivin levels in exhaled breath condensate of lung cancer patients: how hot is the link?. Lung Cancer 2010, 67(1):108-113. 10.1016/j.lungcan.2009.03.033, 19423183.
36. Carpagnano GE, Palladino GP, Lacedonia D, Koutelou A, Orlando S, Foschino-Barbaro MP. Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8. BMC cancer 2011, 11:226. 10.1186/1471-2407-11-226, 3130703, 21649887.
37. Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982, 5(6):649-655. 10.1097/00000421-198212000-00014, 7165009.
38. Goldstraw P, International Association for the Study of Lung Cancer Staging manual in thoracic oncology 2009, Orange Park, FL: Editorial Rx Press, International Association for the Study of Lung Cancer.
39. Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, Van Weel C, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Resp Crit Care 2007, 176(6):532-555.
40. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Supplement 1993, 16:5-40.
41. Haslam PL, Baughman RP. Report of ERS task force: guidelines for measurement of acellular components and standardization of BAL. Eur Respir J 1999, 14(2):245-248.