Covert dissemination of carbapenemase-producing Klebsiella pneumoniae (KPC) in a successfully controlled outbreak: Long- and short-read whole-genome sequencing demonstrate multiple genetic modes of transmission

Journal of Antimicrobial Chemotherapy

Volumn 72, Issue 11, 2017, Pages 3025-3034

  Martin, Jessica ^a,b   Phan, Hang T T ^c,d   Findlay, Jacqueline ^e   Stoesser, Nicole ^c   Pankhurst, Louise ^c   Navickaite, Indre ^c   De Maio, Nicola ^c   Eyre, David W ^c   Toogood, Giles ^b   Orsi, Nicolas M ^a,b   Kirby, Andrew ^a,b   Young, Nicola ^b   Turton, Jane F ^e   Hill, Robert L R ^d   Hopkins, Katie L ^d,e   Woodford, Neil ^d,e   Peto, Tim E A ^c,d   Walker, A Sarah ^c,d   Crook, Derrick W ^c,d   Wilcox, Mark H ^a,b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; CARBAPENEM; CARBAPENEMASE; CIPROFLOXACIN; COLISTIN; ERTAPENEM; BACTERIAL DNA; BACTERIAL PROTEIN; BETA LACTAMASE;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTEREMIA; BACTERIUM ISOLATION; CARBAPENEMASE PRODUCING ENTEROBACTERIACEAE; CARBAPENEMASE PRODUCING KLEBSIELLA PNEUMONIAE; CITROBACTER FREUNDII; CLINICAL ARTICLE; DISEASE TRANSMISSION; ENTEROBACTER CLOACAE; HUMAN; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; LIVER GRAFT; PHENOTYPE; PHYLOGENETIC TREE; PHYLOGENY; POLYMERASE CHAIN REACTION; REPLICON; SINGLE NUCLEOTIDE POLYMORPHISM; TANDEM REPEAT; TRANSPOSON; WHOLE GENOME SEQUENCING; BACTERIAL GENOME; BIOSYNTHESIS; CROSS INFECTION; DNA SEQUENCE; ENTEROBACTERIACEAE; ENZYMOLOGY; EPIDEMIC; FEMALE; GENETICS; HORIZONTAL GENE TRANSFER; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; MALE; MICROBIOLOGY; MIDDLE AGED; MULTILOCUS SEQUENCE TYPING; PLASMID; PROCEDURES; UNITED KINGDOM;

ADULT; AGED; BACTERIAL PROTEINS; BETA-LACTAMASES; CROSS INFECTION; DISEASE OUTBREAKS; DNA, BACTERIAL; ENTEROBACTERIACEAE; FEMALE; GENE TRANSFER, HORIZONTAL; GENOME, BACTERIAL; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; MULTILOCUS SEQUENCE TYPING; PHYLOGENY; PLASMIDS; SEQUENCE ANALYSIS, DNA; UNITED KINGDOM; WHOLE GENOME SEQUENCING;

EID: 85044858219     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkx264     Document Type: Article

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