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Volumn 125, Issue 4, 2018, Pages 549-558

Fully Automated Detection and Quantification of Macular Fluid in OCT Using Deep Learning

Author keywords

[No Author keywords available]

Indexed keywords

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DEEP LEARNING; DIABETIC MACULAR EDEMA; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; HUMAN; LEARNING ALGORITHM; MACHINE LEARNING; MAJOR CLINICAL STUDY; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RECALL; RECEIVER OPERATING CHARACTERISTIC; RETINA IMAGE; RETINA VEIN OCCLUSION; SUBRETINAL FLUID; WET MACULAR DEGENERATION; AGED; COMPARATIVE STUDY; COMPUTER ASSISTED DIAGNOSIS; DIABETIC RETINOPATHY; DIAGNOSTIC IMAGING; FEMALE; MACULAR EDEMA; MALE; MIDDLE AGED; PROCEDURES; REPRODUCIBILITY; VALIDATION STUDY; VISUAL ACUITY;

EID: 85044656432     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2017.10.031     Document Type: Article
Times cited : (452)

References (35)
  • 1
    • 0026254046 scopus 로고
    • Optical coherence tomography
    • Huang, D., Swanson, E.A., Lin, C.P., et al. Optical coherence tomography. Science 254 (1991), 1178–1181.
    • (1991) Science , vol.254 , pp. 1178-1181
    • Huang, D.1    Swanson, E.A.2    Lin, C.P.3
  • 2
    • 84942592863 scopus 로고    scopus 로고
    • Identification of fluid on optical coherence tomography by treating ophthalmologists versus a reading center in the Comparison of Age-Related Macular Degeneration Treatments Trials
    • Toth, C.A., Decroos, F.C., Ying, G.S., et al. Identification of fluid on optical coherence tomography by treating ophthalmologists versus a reading center in the Comparison of Age-Related Macular Degeneration Treatments Trials. Retina 35 (2015), 1303–1314.
    • (2015) Retina , vol.35 , pp. 1303-1314
    • Toth, C.A.1    Decroos, F.C.2    Ying, G.S.3
  • 3
    • 84955388945 scopus 로고    scopus 로고
    • A paradigm shift in imaging biomarkers in neovascular age-related macular degeneration
    • Schmidt-Erfurth, U., Waldstein, S.M., A paradigm shift in imaging biomarkers in neovascular age-related macular degeneration. Prog Retin Eye Res 50 (2016), 1–24.
    • (2016) Prog Retin Eye Res , vol.50 , pp. 1-24
    • Schmidt-Erfurth, U.1    Waldstein, S.M.2
  • 4
    • 84964838121 scopus 로고    scopus 로고
    • Morphology and visual acuity in aflibercept and ranibizumab therapy for neovascular age-related macular degeneration in the VIEW Trials
    • Waldstein, S.M., Simader, C., Staurenghi, G., et al. Morphology and visual acuity in aflibercept and ranibizumab therapy for neovascular age-related macular degeneration in the VIEW Trials. Ophthalmology 123 (2016), 1521–1529.
    • (2016) Ophthalmology , vol.123 , pp. 1521-1529
    • Waldstein, S.M.1    Simader, C.2    Staurenghi, G.3
  • 5
    • 84971224877 scopus 로고    scopus 로고
    • Automated identification of lesion activity in neovascular age-related macular degeneration
    • Chakravarthy, U., Goldenberg, D., Young, G., et al. Automated identification of lesion activity in neovascular age-related macular degeneration. Ophthalmology 123 (2016), 1731–1736.
    • (2016) Ophthalmology , vol.123 , pp. 1731-1736
    • Chakravarthy, U.1    Goldenberg, D.2    Young, G.3
  • 6
    • 84958576660 scopus 로고    scopus 로고
    • Correlation of 3-dimensionally quantified intraretinal and subretinal fluid with visual acuity in neovascular age-related macular degeneration
    • Waldstein, S.M., Philip, A.M., Leitner, R., et al. Correlation of 3-dimensionally quantified intraretinal and subretinal fluid with visual acuity in neovascular age-related macular degeneration. JAMA Ophthalmol 134 (2016), 182–190.
    • (2016) JAMA Ophthalmol , vol.134 , pp. 182-190
    • Waldstein, S.M.1    Philip, A.M.2    Leitner, R.3
  • 7
    • 84973879016 scopus 로고    scopus 로고
    • Learning deconvolution network for semantic segmentation. Proceedings of the IEEE International Conference on Computer Vision; Santiago de Chile, Chile, December 7 – 13.
    • Noh H, Hong S, Han B. Learning deconvolution network for semantic segmentation. Proceedings of the IEEE International Conference on Computer Vision; Santiago de Chile, Chile, December 7 – 13, 2015.
    • (2015)
    • Noh, H.1    Hong, S.2    Han, B.3
  • 8
    • 85044628678 scopus 로고    scopus 로고
    • cuDNN: Efficient Primitives for Deep Learning. Cornell University Library: (submitted on 3Oct2014). arXiv preprint arXiv:14100759
    • Chetlur S, Woolley C, Vandermersch P, et al. cuDNN: Efficient Primitives for Deep Learning. Cornell University Library: https://arxiv.org/abs/1410.0759 (submitted on 3Oct2014). arXiv preprint arXiv:14100759 2014.
    • (2014)
    • Chetlur, S.1    Woolley, C.2    Vandermersch, P.3
  • 9
    • 85044638363 scopus 로고    scopus 로고
    • Theano: a CPU and GPU math expression compiler. Proceedings of the Python for Scientific Computing Conference (SciPy).
    • James B, Olivier B, Frédéric B, et al. Theano: a CPU and GPU math expression compiler. Proceedings of the Python for Scientific Computing Conference (SciPy). https://conference.scipy.org/proceedings/scipy2010/bergstra.html.
    • James, B.1    Olivier, B.2    Frédéric, B.3
  • 10
    • 84973384984 scopus 로고    scopus 로고
    • Lasagne: First Release
    • Zenodo Geneva, Switzerland
    • Dieleman, S., Schlüter, J., Raffel, C., et al. Lasagne: First Release. 2015, Zenodo, Geneva, Switzerland.
    • (2015)
    • Dieleman, S.1    Schlüter, J.2    Raffel, C.3
  • 11
    • 73849122331 scopus 로고    scopus 로고
    • Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images
    • Garvin, M.K., Abramoff, M.D., Wu, X., et al. Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images. IEEE Trans Med Imaging 28 (2009), 1436–1447.
    • (2009) IEEE Trans Med Imaging , vol.28 , pp. 1436-1447
    • Garvin, M.K.1    Abramoff, M.D.2    Wu, X.3
  • 12
    • 16244366026 scopus 로고
    • Index for rating diagnostic tests
    • Youden, W.J., Index for rating diagnostic tests. Cancer 3 (1950), 32–35.
    • (1950) Cancer , vol.3 , pp. 32-35
    • Youden, W.J.1
  • 13
    • 84986321453 scopus 로고    scopus 로고
    • Multivendor spectral-domain optical coherence tomography dataset, observer annotation performance evaluation, and standardized evaluation framework for intraretinal cystoid fluid segmentation
    • Wu, J., Philip, A.M., Podkowinski, D., et al. Multivendor spectral-domain optical coherence tomography dataset, observer annotation performance evaluation, and standardized evaluation framework for intraretinal cystoid fluid segmentation. J Ophthalmol, 2016, 2016, 3898750.
    • (2016) J Ophthalmol , vol.2016 , pp. 3898750
    • Wu, J.1    Philip, A.M.2    Podkowinski, D.3
  • 14
    • 84964865566 scopus 로고    scopus 로고
    • Five-year outcomes with anti-vascular endothelial growth factor treatment of neovascular age-related macular degeneration: the comparison of age-related macular degeneration treatments trials
    • Maguire, M.G., Martin, D.F., Ying, G.S., et al. Five-year outcomes with anti-vascular endothelial growth factor treatment of neovascular age-related macular degeneration: the comparison of age-related macular degeneration treatments trials. Ophthalmology 123 (2016), 1751–1761.
    • (2016) Ophthalmology , vol.123 , pp. 1751-1761
    • Maguire, M.G.1    Martin, D.F.2    Ying, G.S.3
  • 15
    • 84938784440 scopus 로고    scopus 로고
    • Treat-and-extend regimens with anti-VEGF agents in retinal diseases: a literature review and consensus recommendations
    • Freund, K.B., Korobelnik, J.-F., Devenyi, R., et al. Treat-and-extend regimens with anti-VEGF agents in retinal diseases: a literature review and consensus recommendations. Retina 35 (2015), 1489–1506.
    • (2015) Retina , vol.35 , pp. 1489-1506
    • Freund, K.B.1    Korobelnik, J.-F.2    Devenyi, R.3
  • 16
    • 79959608705 scopus 로고    scopus 로고
    • Cystoid macular degeneration in exudative age-related macular degeneration
    • Querques, G., Coscas, F., Forte, R., et al. Cystoid macular degeneration in exudative age-related macular degeneration. Am J Ophthalmol 152 (2011), 100–107.e2.
    • (2011) Am J Ophthalmol , vol.152 , pp. 100-107.e2
    • Querques, G.1    Coscas, F.2    Forte, R.3
  • 17
    • 85044624605 scopus 로고    scopus 로고
    • Prevalence of outer retinal tubulation in eyes with choroidal neovascularization
    • Giachetti Filho, R.G., Zacharias, L.C., Monteiro, T.V., et al. Prevalence of outer retinal tubulation in eyes with choroidal neovascularization. Int J Retina Vitreous, 2, 2016, 6.
    • (2016) Int J Retina Vitreous , vol.2 , pp. 6
    • Giachetti Filho, R.G.1    Zacharias, L.C.2    Monteiro, T.V.3
  • 18
    • 84925373614 scopus 로고    scopus 로고
    • Pigment epithelial detachment followed by retinal cystoid degeneration leads to vision loss in treatment of neovascular age-related macular degeneration
    • Schmidt-Erfurth, U., Waldstein, S.M., Deak, G.G., et al. Pigment epithelial detachment followed by retinal cystoid degeneration leads to vision loss in treatment of neovascular age-related macular degeneration. Ophthalmology 122 (2015), 822–832.
    • (2015) Ophthalmology , vol.122 , pp. 822-832
    • Schmidt-Erfurth, U.1    Waldstein, S.M.2    Deak, G.G.3
  • 19
    • 78049279239 scopus 로고    scopus 로고
    • A treat and extend regimen using ranibizumab for neovascular age-related macular degeneration clinical and economic impact
    • Gupta, O.P., Shienbaum, G., Patel, A.H., et al. A treat and extend regimen using ranibizumab for neovascular age-related macular degeneration clinical and economic impact. Ophthalmology 117 (2010), 2134–2140.
    • (2010) Ophthalmology , vol.117 , pp. 2134-2140
    • Gupta, O.P.1    Shienbaum, G.2    Patel, A.H.3
  • 20
    • 84921555945 scopus 로고    scopus 로고
    • Intravitreal ranibizumab for diabetic macular edema with prompt versus deferred laser treatment: 5-year randomized trial results
    • Elman, M.J., Ayala, A., Bressler, N.M., et al. Intravitreal ranibizumab for diabetic macular edema with prompt versus deferred laser treatment: 5-year randomized trial results. Ophthalmology 122 (2015), 375–381.
    • (2015) Ophthalmology , vol.122 , pp. 375-381
    • Elman, M.J.1    Ayala, A.2    Bressler, N.M.3
  • 21
    • 84953431892 scopus 로고    scopus 로고
    • Macular morphology and visual acuity in the second year of the Comparison of Age-Related Macular Degeneration Treatments Trials
    • Sharma, S., Toth, C.A., Daniel, E., et al. Macular morphology and visual acuity in the second year of the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 123 (2016), 865–875.
    • (2016) Ophthalmology , vol.123 , pp. 865-875
    • Sharma, S.1    Toth, C.A.2    Daniel, E.3
  • 22
    • 84937724063 scopus 로고    scopus 로고
    • Predictors of functional and anatomic outcomes in patients with diabetic macular edema treated with ranibizumab
    • Sophie, R., Lu, N., Campochiaro, P.A., Predictors of functional and anatomic outcomes in patients with diabetic macular edema treated with ranibizumab. Ophthalmology 122 (2015), 1395–1401.
    • (2015) Ophthalmology , vol.122 , pp. 1395-1401
    • Sophie, R.1    Lu, N.2    Campochiaro, P.A.3
  • 23
    • 84962408693 scopus 로고    scopus 로고
    • The role of sub-retinal fluid in determining treatment outcomes in patients with neovascular age-related macular degeneration–a phase IV randomised clinical trial with ranibizumab: the FLUID study
    • Arnold, J.J., Markey, C.M., Kurstjens, N.P., Guymer, R.H., The role of sub-retinal fluid in determining treatment outcomes in patients with neovascular age-related macular degeneration–a phase IV randomised clinical trial with ranibizumab: the FLUID study. BMC Ophthalmol, 16, 2016, 31.
    • (2016) BMC Ophthalmol , vol.16 , pp. 31
    • Arnold, J.J.1    Markey, C.M.2    Kurstjens, N.P.3    Guymer, R.H.4
  • 24
    • 85044561343 scopus 로고    scopus 로고
    • A view of the current and future role of optical coherence tomography in the management of age-related macular degeneration
    • Schmidt-Erfurth, U., Klimscha, S., Waldstein, S.M., Bogunovic, H., A view of the current and future role of optical coherence tomography in the management of age-related macular degeneration. Eye (Lond) 31 (2017), 26–44.
    • (2017) Eye (Lond) , vol.31 , pp. 26-44
    • Schmidt-Erfurth, U.1    Klimscha, S.2    Waldstein, S.M.3    Bogunovic, H.4
  • 25
    • 85016221341 scopus 로고    scopus 로고
    • Automated identification of diabetic retinopathy using deep learning
    • Gargeya, R., Leng, T., Automated identification of diabetic retinopathy using deep learning. Ophthalmology 124 (2017), 962–969.
    • (2017) Ophthalmology , vol.124 , pp. 962-969
    • Gargeya, R.1    Leng, T.2
  • 26
    • 84990193991 scopus 로고    scopus 로고
    • Improved automated detection of diabetic retinopathy on a publicly available dataset through integration of deep learning
    • Abramoff, M.D., Lou, Y., Erginay, A., et al. Improved automated detection of diabetic retinopathy on a publicly available dataset through integration of deep learning. Invest Ophthalmol Vis Sci 57 (2016), 5200–5206.
    • (2016) Invest Ophthalmol Vis Sci , vol.57 , pp. 5200-5206
    • Abramoff, M.D.1    Lou, Y.2    Erginay, A.3
  • 27
    • 85027881492 scopus 로고    scopus 로고
    • Deep learning is effective for classifying normal versus age-related macular degeneration optical coherence tomography images
    • Lee, C.S., Baughman, D.M., Lee, A.Y., Deep learning is effective for classifying normal versus age-related macular degeneration optical coherence tomography images. Ophthalmol Retina 1 (2017), 322–327.
    • (2017) Ophthalmol Retina , vol.1 , pp. 322-327
    • Lee, C.S.1    Baughman, D.M.2    Lee, A.Y.3
  • 28
    • 84873368761 scopus 로고    scopus 로고
    • Quantification of external limiting membrane disruption caused by diabetic maular edema from SD-OCT
    • Chen, X., Zhang, L., Sohn, E.H., et al. Quantification of external limiting membrane disruption caused by diabetic maular edema from SD-OCT. Invest Ophthalmol Vis Sci 53:13 (2012), 8042–8048.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , Issue.13 , pp. 8042-8048
    • Chen, X.1    Zhang, L.2    Sohn, E.H.3
  • 29
    • 23844531558 scopus 로고    scopus 로고
    • Delineating fluid-filled region boundaries in optical coherence tomography images of the retina
    • Fernandez, D.C., Delineating fluid-filled region boundaries in optical coherence tomography images of the retina. IEEE Trans Med Imaging 24 (2005), 929–945.
    • (2005) IEEE Trans Med Imaging , vol.24 , pp. 929-945
    • Fernandez, D.C.1
  • 30
    • 84858994994 scopus 로고    scopus 로고
    • Automated segmentation of intraretinal cystoid fluid in optical coherence tomography
    • Wilkins, G.R., Houghton, O.M., Oldenburg, A.L., Automated segmentation of intraretinal cystoid fluid in optical coherence tomography. IEEE Trans Biomed Eng 59 (2012), 1109–1114.
    • (2012) IEEE Trans Biomed Eng , vol.59 , pp. 1109-1114
    • Wilkins, G.R.1    Houghton, O.M.2    Oldenburg, A.L.3
  • 31
    • 84936749926 scopus 로고    scopus 로고
    • Stratified sampling voxel classification for segmentation of intraretinal and subretinal fluid in longitudinal clinical OCT data
    • Xu, X., Lee, K., Zhang, L., et al. Stratified sampling voxel classification for segmentation of intraretinal and subretinal fluid in longitudinal clinical OCT data. IEEE Trans Med Imaging 34:7 (2015), 1616–1623.
    • (2015) IEEE Trans Med Imaging , vol.34 , Issue.7 , pp. 1616-1623
    • Xu, X.1    Lee, K.2    Zhang, L.3
  • 32
    • 84942617306 scopus 로고    scopus 로고
    • Kernel regression based segmentation of optical coherence tomography images with diabetic macular edema
    • Chiu, S.J., Allingham, M.J., Mettu, P.S., et al. Kernel regression based segmentation of optical coherence tomography images with diabetic macular edema. Biomed Opt Express 6 (2015), 1172–1194.
    • (2015) Biomed Opt Express , vol.6 , pp. 1172-1194
    • Chiu, S.J.1    Allingham, M.J.2    Mettu, P.S.3
  • 33
    • 84962895445 scopus 로고    scopus 로고
    • Automated volumetric segmentation of retinal fluid on optical coherence tomography
    • Wang, J., Zhang, M., Pechauer, A.D., et al. Automated volumetric segmentation of retinal fluid on optical coherence tomography. Biomed Opt Express 7 (2016), 1577–1589.
    • (2016) Biomed Opt Express , vol.7 , pp. 1577-1589
    • Wang, J.1    Zhang, M.2    Pechauer, A.D.3
  • 34
    • 84983548350 scopus 로고    scopus 로고
    • predicting semantic descriptions from medical images with convolutional neural networks
    • Schlegl, T., Waldstein, S.M., Schmidt-Erfurth, U., Langs, G., predicting semantic descriptions from medical images with convolutional neural networks. Inf Process Med Imaging 24 (2015), 437–448.
    • (2015) Inf Process Med Imaging , vol.24 , pp. 437-448
    • Schlegl, T.1    Waldstein, S.M.2    Schmidt-Erfurth, U.3    Langs, G.4
  • 35
    • 85020063148 scopus 로고    scopus 로고
    • Morphological parameters relevant for visual and anatomic outcomes during anti-VEGF therapy of diabetic macular edema in the RESTORE trial
    • Gerendas, B., Simader, C., Deak, G.G., et al. Morphological parameters relevant for visual and anatomic outcomes during anti-VEGF therapy of diabetic macular edema in the RESTORE trial. Invest Ophthalmol Vis Sci, 55, 2014, 1791.
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 1791
    • Gerendas, B.1    Simader, C.2    Deak, G.G.3


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