-
1
-
-
84880452562
-
Genomics-driven oncology: Framework for an emerging paradigm
-
Garraway, L. A. Genomics-Driven Oncology: Framework for an Emerging Paradigm. J. Clin. Oncol. 31, 1806-1814 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 1806-1814
-
-
Garraway, L.A.1
-
2
-
-
85011275698
-
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer
-
Griffith, M. et al. CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer. Nat. Genet. 49, 170-174 (2017).
-
(2017)
Nat. Genet.
, vol.49
, pp. 170-174
-
-
Griffith, M.1
-
3
-
-
84874025843
-
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
-
Cibulskis, K. et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat. Biotechnol. 31, 213-219 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 213-219
-
-
Cibulskis, K.1
-
4
-
-
84964545042
-
Deciphering intratumor heterogeneity using cancer genome analysis
-
Ryu, D., Joung, J.-G., Kim, N. K. D., Kim, K.-T. &Park, W.-Y. Deciphering intratumor heterogeneity using cancer genome analysis. Hum. Genet. 135, 635-642 (2016).
-
(2016)
Hum. Genet.
, vol.135
, pp. 635-642
-
-
Ryu, D.1
Joung, J.-G.2
Kim, N.K.D.3
Kim, K.-T.4
Park, W.-Y.5
-
5
-
-
84971222718
-
Mechanisms and consequences of cancer genome instability: Lessons from genome sequencing studies
-
Lee, J.-K., Choi, Y.-L., Kwon, M. &Park, P. J. Mechanisms and Consequences of Cancer Genome Instability: Lessons from Genome Sequencing Studies. Annu. Rev. Pathol. 11, 283-312 (2016).
-
(2016)
Annu. Rev. Pathol.
, vol.11
, pp. 283-312
-
-
Lee, J.-K.1
Choi, Y.-L.2
Kwon, M.3
Park, P.J.4
-
6
-
-
84928105158
-
Memorial sloan kettering-integrated mutation profiling of actionable cancer targets (msk-impact): A hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology
-
Cheng, D. T. et al. Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology. J. Mol. Diagn. 17, 251-264 (2015).
-
(2015)
J. Mol. Diagn.
, vol.17
, pp. 251-264
-
-
Cheng, D.T.1
-
7
-
-
85020279899
-
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
-
Zehir, A. et al. Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. Nat. Med. 23, 703-713 (2017).
-
(2017)
Nat. Med.
, vol.23
, pp. 703-713
-
-
Zehir, A.1
-
8
-
-
84860782006
-
Absolute quantification of somatic DNA alterations in human cancer
-
Carter, S. L. et al. Absolute quantification of somatic DNA alterations in human cancer. Nat. Biotechnol. 30, 413-421 (2012).
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 413-421
-
-
Carter, S.L.1
-
9
-
-
84949564442
-
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
-
Alioto, T. S. et al. A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing. Nat. Commun. 6, 10001 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 10001
-
-
Alioto, T.S.1
-
10
-
-
85013170830
-
DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification
-
Chen, L., Liu, P., Evans, T. C. Jr. &Ettwiller, L. M. DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification. Science 355, 752-756 (2017).
-
(2017)
Science
, vol.355
, pp. 752-756
-
-
Chen, L.1
Liu, P.2
Evans, T.C.3
Ettwiller, L.M.4
-
12
-
-
84864153492
-
Strelka: Accurate somatic small-variant calling from sequenced tumor-normal sample pairs
-
Saunders, C. T. et al. Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs. Bioinformatics 28, 1811-1817 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 1811-1817
-
-
Saunders, C.T.1
-
13
-
-
84995483126
-
Conpair: Concordance and contamination estimator for matched tumor-normal pairs
-
Bergmann, E. A., Chen, B.-J., Arora, K., Vacic, V. &Zody, M. C. Conpair: concordance and contamination estimator for matched tumor-normal pairs. Bioinformatics 32, 3196-3198 (2016).
-
(2016)
Bioinformatics
, vol.32
, pp. 3196-3198
-
-
Bergmann, E.A.1
Chen, B.-J.2
Arora, K.3
Vacic, V.4
Zody, M.C.5
-
15
-
-
84874102335
-
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
-
Landau, D. A. et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell 152, 714-726 (2013).
-
(2013)
Cell
, vol.152
, pp. 714-726
-
-
Landau, D.A.1
-
16
-
-
84928254065
-
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
-
McGranahan, N. et al. Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. Sci. Transl. Med. 7, 283ra54 (2015).
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 283ra54
-
-
McGranahan, N.1
-
17
-
-
84944916590
-
The influence of subclonal resistance mutations on targeted cancer therapy
-
Schmitt, M. W., Loeb, L. A. &Salk, J. J. The influence of subclonal resistance mutations on targeted cancer therapy. Nat. Rev. Clin. Oncol. 13, 335-347 (2016).
-
(2016)
Nat. Rev. Clin. Oncol.
, vol.13
, pp. 335-347
-
-
Schmitt, M.W.1
Loeb, L.A.2
Salk, J.J.3
-
18
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
Li, H. &Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
19
-
-
77956295988
-
The genome analysis toolkit: A mapreduce framework for analyzing next-generation DNA sequencing data
-
McKenna, A. et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 20, 1297-1303 (2010).
-
(2010)
Genome Res.
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
|