Early intervention (mobilization or active exercise) for critically ill adults in the intensive care unit

Cochrane Database of Systematic Reviews

Volumn 2018, Issue 3, 2018, Pages

  Doiron, Katherine A ^a   Hoffmann, Tammy C ^a   Beller, Elaine M ^a  

^a BOND UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTIFICIAL VENTILATION; CRITICAL ILLNESS; DAILY LIFE ACTIVITY; EXERCISE; HUMAN; INTENSIVE CARE UNIT; MOBILIZATION; MUSCLE STRENGTH; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC);

ACTIVITIES OF DAILY LIVING; ADULT; CRITICAL ILLNESS; EARLY AMBULATION; EXERCISE; HUMANS; INTENSIVE CARE UNITS; MUSCLE STRENGTH; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESPIRATION, ARTIFICIAL;

EID: 85044504626     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD010754.pub2     Document Type: Review

References (77)

1. Kayambu G, Boots R, Paratz J. Early physical rehabilitation in intensive care patients with sepsis syndromes: a pilot randomised controlled trial. Intensive Care Medicine 2015;41:865-74. [PUBMED: 25851383]7855092
2. Morris PE, Berry MJ, Files DC, Thompson JC, Hauser J, Flores L, et al. Standardized rehabilitation and hospital length of stay among patients with acute respiratory failure: a randomized clinical trial. JAMA 2016;315(4):2694-702. [PUBMED: 27367766]7855094
3. Patman S, Sanderson D, Blackmore M. Physiotherapy following cardiac surgery: is it necessary during the intubation period?. Australian Journal of Physiotherapy 2001;47:7-16. [PUBMED: 11552858]7855096
4. Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CE, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 2009;373:1874-82. [PUBMED: 19446324 ]7855098
5. Brummel NE, Girard TD, Ely EW, Pandharipande PP, Morandi A, Hughes CG, et al. Feasibility and safety of early combined cognitive and physical therapy for critically ill medical and surgical patients: the activity and cognitive therapy in ICU (ACT-ICU) trial. Intensive Care Medicine 2014;40(3):370-9. [PUBMED: 24257969]7855100
6. Burtin C, Clerckx B, Robbeets C, Ferdinande P, Langer D, Troosters T, et al. Early exercise in critically ill patients enhances short-term functional recovery. Critical Care Medicine 2009;37(9):2499-505. [PUBMED: 19623052]7855102
7. Chen YH, Lin HL, Hsiao HF, Chou LT, Kao KC, Huang CC, et al. Effects of exercise training on pulmonary mechanics and functional status in patients with prolonged mechanical ventilation. Respiratory Care 2012;57(5):727-34. [PUBMED: 22152978]7855104
8. Chiang LL, Wang LY, Wu CP, Wu HD, Wu YT. Effects of physical training on functional status in patients with prolonged mechanical ventilation. Physical Therapy 2006;86(9):1271-81. [PUBMED: 16959675]7855106
9. Collings N, Cusack R. A repeated measures, randomised cross-over trial, comparing the acute exercise response between passive and active sitting in critically ill patients. BMC Anesthesiology 2015;15(1):1-8. [PUBMED: 25670916]7855108
10. Denehy L, Skinner EH, Edbrooke L, Haines K, Warrillow S, Hawthorne G, et al. Exercise rehabilitation for patients with critical illness: a randomised controlled trial with 12 months of follow-up. Critical Care 2013;17(4):1-12. [PUBMED: 23883525]7855110
11. ISRCTN20436833. Extra physiotherapy in critical care: intensive versus standard physical rehabilitation therapy in the critically ill. apps.who.int/trialsearch/default.aspx/ISRCTN20436833 (accessed 5 April 2015). 7855112
12. Médrinal C, Lebret M, Bousta M, Nassaj A, Colas G. Effects of sitting at the bedside of the patient with mechanical ventilation [Efffets de la station assise au bord du lit du patient intubé et ventilé]. Kinésithérapie, la Revue 2013;13(138):43-9. [DOI: 10.1016/j.kine.2012.12.073]7855114
13. Morris PE, Goad A, Thompson C, Taylor K, Harry B, Passmore L, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Critical Care Medicine 2008;36(8):2238-43. [PUBMED: 18596631]7855116
14. Moss M, Nordon-Craft A, Malone D, Van Pelt D, Frankel SK, Warner ML, et al. A randomized trial of an intensive physical therapy program for patients with acute respiratory failure. American Journal of Respiratory and Critical Care Medicine 2016;193(10):1101-10. 7855118
15. Nava S. Rehabilitation of patients admitted to a respiratory intensive care unit. Archives of Physical Medicine and Rehabilitation 1998;79(7):849-54. [PUBMED: 9685104]7855120
16. NCT01058421. Treatment of critical illness polyneuromyopathy. apps.who.int/trialsearch/default.aspx/NCT01058421 (accessed 5 April 2015). 7855122
17. Porta R, Vitacca M, Gilè LS, Clini E, Bianchi L, Zanotti E, et al. Supporting arm training in patients recently weaned from mechanical ventilation. Chest 2005;128(4):2511-20. [PUBMED: 16236917]7855124
18. Yosef-Brauner O, Adi N, Ben Shahar T, Yehezkel E, Carmeli E. Effect of physical therapy on muscle strength, respiratory muscles and functional parameters in patients with intensive care unit-acquired weakness. The Clinical Respiratory Journal 2015;9(1):1-6. [PUBMED: 24345055]7855126
19. Dong Z, Yu B, Sun Y, Fang W, Li L. Effects of early rehabilitation therapy on patients with mechanical ventilation. World Journal of Emergency Medicine 2014;5(1):48-52. [PUBMED: 25215147]7855128
20. Files D, Morris P, Shrestha S, Dhar S, Young M, Hauser J, et al. Randomized, controlled pilot study of early rehabilitation strategies in acute respiratory failure. Critical Care 2013;17 (Suppl 2):540. [DOI: 10.1186/cc12478]7855130
21. Malicdem MG, Cruz BO-D, Punzal P, De Guia T. Outcome of pulmonary rehabilitation among difficult to wean patients admitted at the Philippine Heart Center - a randomized controlled study. Respirology 2010;15:99. 7855132
22. Susa A, Roveran A, Bocchi A, Carrer S, Tartari S. FastTrack approach to major colorectal surgery [Approccio FastTrack alla chirurgia colorettale maggiore]. Chirurgia Italiana 2004;56(6):817-24. 7855134
23. NCT01927510. TEAM: a trial of early activity and mobility in ICU (TEAM-RCT). clinicaltrials.gov/ct2/show/NCT01927510 first received 22 August 2013. 7855136
24. NCT01960868. Early rehabilitation program is feasible and safe in ICU in liver transplanted patients. clinicaltrials.gov/ct2/show/NCT01960868 first received 11 October 2013. 7855138
25. RBR-6sz5dj. Use of de game therapy to assess functionality and upper limb muscle strength in critical patients. www.ensaiosclinicos.gov.br/rg/RBR-6sz5dj/ first received 29 May 2012. 7855140
26. Adler J, Malone D. Early mobilization in the intensive care unit: a systematic review. Cardiopulmonary Physical Therapy Journal 2012;23(1):5-13. [PUBMED: 22807649]
27. Ali NA, O'Brien JM, Hoffman SP, Phillips G, Garland A, Finley JC, et al. Acquired weakness, handgrip strength, and mortality in critically ill patients. American Journal of Respiratory and Critical Care Medicine 2008;178(3):261-8. [PUBMED: 18511703]
28. Bailey P, Thomsen GE, Spuhler VJ, Blair R, Jewkes J, Bezdjian L, et al. Early activity is feasible and safe in respiratory failure patients. Critical Care Medicine 2007;35(1):139-45. [PUBMED: 17133183]
29. Castro-Avila AC, Seron P, Fan E, Gaete M, Mickan S. Effect of early rehabilitation during intensive care unit stay on functional status: systematic review and meta-analysis. PLoS One 2015;10(7):e0130722.
30. Chlan LL, Weinert CR, Skaar DJ, Tracy MF. Patient-controlled sedation: a novel approach to sedation management for mechanically ventilated patients. Chest 2010;138(5):1045-53. [PUBMED: 20299632]
31. Choi J, Tasota FJ, Hoffman LA. Mobility interventions to improve outcomes in patients undergoing prolonged mechanical ventilation: a review of the literature. Biological Research for Nursing 2008;10(1):21-33. [PUBMED: 18647758]
32. Connolly B, Salisbury L, O'Neill B, Geneen L, Douiri A, Grocott MP, et al. Exercise rehabilitation following intensive care unit discharge for recovery from critical illness. Cochrane Database of Systematic Reviews 2015, Issue 6. [DOI: 10.1002/14651858.CD008632.pub2]
33. Crapo RO, Casaburi R, Coates AL, Enright PL, MacIntyre NR, McKay RT, et al. ATS statement: guidelines for the six-minute walk test. American Journal of Respiratory and Critical Care Medicine 2002;166(1):111-7. [PUBMED: 12091180]
34. DeJonghe B, Sharshar T, Lefaucheur JP, Authier FJ, Durand-Zaleski I, Boussarsar M, et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA 2002;288(22):2859-67. [PUBMED: 12472328]
35. Desai SV, Law TJ, Needham DM. Long-term complications of critical care. Critical Care Medicine 2011;39(2):371-9. [PUBMED: 20959786]
36. Dos Santos C, Hussain SN, Mathur S, Picard M, Herridge M, Correa J, et al MEND ICU Group, RECOVER Program Investigators, Canadian Critical CareTranslational Biology Group. Mechanisms of chronic muscle wasting and dysfunction after an Intensive Care Unit stay: a pilot study. American Journal of Respiratory and Critical Care Medicine 2016;194:821-30.
37. Fan E, Dowdy DW, Colantuoni E, Mendez-Tellez PA, Sevransky JE, Shanholtz C, et al. Physical complications in acute lung injury survivors: a two-year longitudinal prospective study. Critical Care Medicine 2014;42(4):849-59. [PUBMED: 24247473]
38. Gielen S, Schuler G, Adams V. Cardiovascular effects of exercise training: molecular mechanisms. Circulation 2010;122:1221-38. [PUBMED: 20855669]
39. McMaster University (developed by Evidence Prime). GRADEpro GDT. Version Accessed August 2017. Hamilton (ON): McMaster University (developed by Evidence Prime), 2015.
40. Greve I, Vasilevskis EE, Egerod I, Bekker Mortensen C, Møller AM, Svenningsen H, et al. Interventions for preventing intensive care unit delirium. Cochrane Database of Systematic Reviews 2012, Issue 8. [DOI: 10.1002/14651858.CD009783]
41. Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Schunemann HJ. What is "quality of evidence" and why is it important to clinicians. BMJ 2008;336:995-8.
42. Hermans G, Van Mechelen H, Clerckx B, Vanhullebusch T, Mesotten D, Wilmer A, et al. Acute outcomes and 1-year mortality of intensive care unit-acquired weakness: a cohort study and propensity-matched analysis. American Journal of Respiratory and Critical Care Medicine 2014;190(4):410-20. [PUBMED: 24825371]
43. Hermans G, De Jonghe B, Bruyninckx F, Van den Berghe G. Interventions for preventing critical illness polyneuropathy and critical illness myopathy. Cochrane Database of Systematic Reviews 2014, Issue 1. [DOI: 10.1002/14651858.CD006832.pub3]
44. Hermans G, Van den Berghe, G. Clinical review: intensive care unit acquired weakness. Critical Care 2015;19:274. [PUBMED: 26242743 ; PUBMED: 10.1186/s13054-015-0993-7]
45. Herridge MS, Angus DC. Acute lung injury - affecting many lives. New England Journal of Medicine 2005;353(16):1736-8. [PUBMED: 16236746]
46. Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, et al. Functional disability 5 years after acute respiratory distress syndrome. New England Journal of Medicine 2011;364(14):1293-304. [PUBMED: 21470008]
47. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003; Vol. 327:557-60.
48. Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from handbook.cochrane.org.
49. Hodgson CL, Stiller K, Needham DM, Tipping CJ, Harrold M, Baldwin CE, et al. Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults. Critical Care 2014;18(6):658. [PUBMED: 25475522]
50. Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ 2014;348(g1687):1-12. [DOI: 10.1136/bmj.g1687]
51. Jolley SE, Regan-Baggs J, Dickson RP, Hough CL. Medical intensive care unit clinician attitudes and perceived barriers towards early mobilization of critically ill patients: a cross-sectional survey study. BMC Anesthesiology 2014;14(84):1-9. [PUBMED: 25309124 ]
52. Kayambu G, Boots R, Paratz J. Physical therapy for the critically ill in the ICU: a systematic review and meta-analysis. Critical Care Medicine 2013;41:1543-54.
53. Keith RA, Granger CV, Hamilton BB, Sherwin FS. The functional independence measure: a new tool for rehabilitation. Advances in Clinical Rehabilitation 1987;1:6-18. [PUBMED: 3503663]
54. Koo KK, Choong K, Fan E. Prioritizing rehabilitation strategies in the care of the critically ill. Critical Care Rounds 2011;8(4):1-7.
55. Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. New England Journal of Medicine 2000;342(20):1471-7. [MEDLINE: 10816184]
56. Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JP, Green S, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from handbook.cochrane.org.
57. Li Z, Peng X, Zhu B, Zhang Y, Xi X. Active mobilization for mechanically ventilated patients: a systematic review. Archives of Physical Medicine and Rehabilitation 2013;94(3):551-61. [PUBMED: 23127305]
58. Mahoney Fl, Barthel DW. Functional evaluation: the Barthel Index. Maryland State Medical Journal 1965;14(2):61-5. [PUBMED: 14258950]
59. Medical Research Council. Nerve Injuries Research Committee. Aids to examination of the peripheral nervous system. His Majesty's Stationery Office 1942:48 (iii).
60. Mehrholz J, Pohl M, Kugler J, Burridge J, Mückel S, Elsner B. Physical rehabilitation for critical illness myopathy and neuropathy. Cochrane Database of Systematic Reviews 2015, Issue 3. [DOI: 10.1002/14651858.CD010942.pub2]
61. Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, et al. Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference. Critical Care Medicine 2012;40(2):502-9. [PUBMED: 21946660]
62. Parry SM, El-Ansary D, Cartwright MS, Sarwal A, Berney S, Koopman R, et al. Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function. Journal of Critical Care 2015;30(5):1151.e9-14. [PUBMED: 26211979]
63. Pinheiro AR, Christofoletti G. Motor physical therapy in hospitalized patients in an intensive care unit: a systematic review [Fisioterupia motora em pacientes internados na unidade de terapia intensiva: uma revisão sistemática]. Revista Brasileira de Terapia Intensiva 2012;24(2):188-96. [PUBMED: 23917769]
64. Portney L, Watkins M. Foundations of Clinical Research: Applications to Practice. Norwalk, Connecticut: Appleton and Lange, 1993.
65. Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, et al. Acute skeletal muscle wasting in critical illness. JAMA 2013;310(15):1591-600. [PUBMED: 24108501]
66. Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager 5 (RevMan 5). Version 5.3. Copenhagen: Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
67. Schulz KF, Grimes DA. Blinding in randomised trials: hiding who got what. Lancet 2002;359(9307):696-700. [PUBMED: 11879884]
68. Skinner EH, Berney S, Warrillow S, Denehy L. Development of a physical function outcome measure (PFIT) and a pilot exercise training protocol for use in intensive care. Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine 2009;11(2):110-5. [PUBMED: 19485874]
69. Stevens RD, Dowdy DW, Michaels RK, Mendez-Tellez PA, Pronovost PJ, Needham DM. Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Medicine 2007;33:1876-91. [PUBMED: 17639340]
70. Stiller K. Physiotherapy in intensive care: an updated systematic review. Chest 2013;144(3):825-47. [DOI: 10.1378/chest.12-2930; PUBMED: 23722822]
71. Strøm T, Stylsvig M, Toft P. Long-term psychological effects of a no-sedation protocol in critically ill patients. Critical Care 2011 [Epub ahead of print];15(6):R293. [PUBMED: 22166673]
72. Thomas A. Physiotherapy led early rehabilitation of the patient with critical illness. Physical Therapy Reviews 2011;16(1):46-57. [DOI: 10.1179/1743288X10Y.0000000022]
73. Tipping CJ, Young PJ, Romero L, Saxena MK, Dulhunty J, Hodgson CL. A systematic review of measurements of physical function in critically ill adults. Critical Care and Resuscitation 2012;14(4):302-11. [PUBMED: 23230880]
74. Turnbull AE, Rabiee A, Davis WE, Nasser MF, Venner VR, Lolitha R, et al. Outcome measurement in ICU survivorship research from 1970-2013: a scoping review of 425 publications. Critical Care Medicine July 2016;44(7):1267-77.
75. Van Dillen LR, Roach KE. Reliability and validity of the Acute Care Index of Function for patients with neurologic impairment. Physical Therapy 1988;68(7):1098-101. [PUBMED: 3387465]
76. Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Concept framework and item selection. Medical Care 1992;30(6):473-83. [PUBMED: 1593914]
77. Doiron KA, Hoffmann T, Beller EM. Early intervention (mobilization or active exercise) for critically ill patients in the intensive care unit. Cochrane Database of Systematic Reviews 2013, Issue 10. [DOI: 10.1002/14651858.CD010754]