Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter -Derived Cephalosporinase-7, a Unique Class C β-Lactamase

ACS Infectious Diseases

Volumn 4, Issue 3, 2018, Pages 325-336

  Bouza, Alexandra A ^a   Swanson, Hollister C ^a   Smolen, Kali A ^a   Vandine, Alison L ^a   Taracila, Magdalena A ^c,d   Romagnoli, Chiara ^b   Caselli, Emilia ^b   Prati, Fabio ^b   Bonomo, Robert A ^c,d   Powers, Rachel A ^a   Wallar, Bradley J ^a  

^a GRAND VALLEY STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; BETA LACTAMASE INHIBITOR; BORONIC ACID DERIVATIVE; CEFALOTIN; CEFTAZIDIME; CEPHALOSPORINASE; CR 157; CR 161; CR 167; CR 192; S 06017; UNCLASSIFIED DRUG; PROTEIN BINDING;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROGEN BOND; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; STEADY STATE; THERMOSTABILITY; ACINETOBACTER; BINDING SITE; CHEMISTRY; ENZYMOLOGY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ACINETOBACTER; BETA-LACTAMASE INHIBITORS; BINDING SITES; BORONIC ACIDS; CEPHALOSPORINASE; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 85043481496     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.7b00152     Document Type: Article

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