Impaired left atrial systolic function and inter-atrial dyssynchrony may contribute to symptoms of heart failure with preserved left ventricular ejection fraction: A comprehensive assessment by echocardiography

International Journal of Cardiology

Volumn 257, Issue , 2018, Pages 177-181

  Liu, Shuang ^a   Guan, Zhengyu ^a   Zheng, Xianfeng ^a   Meng, Pingping ^a   Wang, Yonghuai ^a   Li, Yang ^a   Zhang, Yan ^a   Yang, Jun ^a   Jia, Dalin ^a   Ma, Chunyan ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DETERIORATION; FEMALE; HEART ATRIUM FUNCTION; HEART FAILURE WITH PRESERVED EJECTION FRACTION; HUMAN; INTERATRIAL DYSSYNCHRONY; LEFT ATRIAL ACTIVE EJECTION FRACTION; LEFT ATRIAL DIASTOLIC FUNCTION; LEFT ATRIAL SYSTOLIC FUNCTION; LEFT VENTRICULAR DIASTOLIC DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; NEW YORK HEART ASSOCIATION CLASS; PEAK ATRIAL CONTRACTION STRAIN; PEAK ATRIAL LONGITUDINAL SYSTOLIC STRAIN; PRIORITY JOURNAL; SPECKLE TRACKING ECHOCARDIOGRAPHY; TISSUE DOPPLER IMAGING; AGED; ATRIAL FIBRILLATION; DIAGNOSTIC IMAGING; DOPPLER ECHOCARDIOGRAPHY; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; STANDARDS;

AGED; ATRIAL FIBRILLATION; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; STROKE VOLUME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 85042664654     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2017.12.042     Document Type: Article

References (33)

1. Laurent, G., Eicher, J.C., Mathe, A., Bertaux, G., Barthez, O., Debin, R., et al. Permanent left atrial pacing therapy may improve symptoms in heart failure patients with preserved ejection fraction and atrial dyssynchrony: a pilot study prior to a national clinical research programme. Eur. J. Heart Fail. 15 (2013), 85–93.
2. Paulus, W.J., Flachskampf, F.A., Smiseth, O.A., Fraser, A.G., How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology: reply. Eur. Heart J. 28 (2007), 2686–2687.
3. Ito, T., Suwa, M., Kobashi, A., Yagi, H., Hirota, Y., Kawamura, K., Reversible left atrial dysfunction possibly due to afterload mismatch in patients with left ventricular dysfunction. J. Am. Soc. Echocardiogr. 11 (1998), 274–279.
4. Morris, D.A., Gailani, M., Vaz Perez, A., Blaschke, F., Dietz, R., Haverkamp, W., et al. Left atrial systolic and diastolic dysfunction in heart failure with normal left ventricular ejection fraction. J. Am. Soc. Echocardiogr. 24 (2011), 651–662.
5. Mondillo, S., Cameli, M., Caputo, M.L., Lisi, M., Palmerini, E., Padeletti, M., et al. Early detection of left atrial strain abnormalities by speckle-tracking in hypertensive and diabetic patients with normal left atrial size. J. Am. Soc. Echocardiogr. 24 (2011), 898–908.
6. Kurt, M., Wang, J., Torre-Amione, G., Nagueh, S.F., Left atrial function in diastolic heart failure. Circ. Cardiovasc. Imaging 2 (2009), 10–15.
7. Singh, A., Addetia, K., Maffessanti, F., Mor-Avi, V., Lang, R.M.L.A., Strain for categorization of LV diastolic dysfunction. JACC Cardiovasc. Imaging 10 (2017), 735–743.
8. Kuppahally, S.S., Akoum, N., Burgon, N.S., Badger, T.J., Kholmovski, E.G., Vijayakumar, S., et al. Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI. Circ. Cardiovasc. Imaging 3 (2010), 231–239.
9. Eicher, J.C., Laurent, G., Mathe, A., Barthez, O., Bertaux, G., Philip, J.L., et al. Atrial dyssynchrony syndrome: an overlooked phenomenon and a potential cause of ‘diastolic’ heart failure. Eur. J. Heart Fail. 14 (2012), 248–258.
10. Sanchis, L., Vannini, L., Gabrielli, L., Duchateau, N., Falces, C., Andrea, R., et al. Interatrial dyssynchrony may contribute to heart failure symptoms in patients with preserved ejection fraction. Echocardiography 32 (2015), 1655–1661.
11. Ramsaran, E.K., Spodick, D.H., Electromechanical delay in the left atrium as a consequence of interatrial block. Am. J. Cardiol. 77 (1996), 1132–1134.
12. Bertini, M., Borleffs, C.J., Delgado, V., Ng, A.C., Piers, S.R., Shanks, M., et al. Prediction of atrial fibrillation in patients with an implantable cardioverter-defibrillator and heart failure. Eur. J. Heart Fail. 12 (2010), 1101–1110.
13. Nagueh, S.F., Smiseth, O.A., Appleton, C.P., Byrd, B.F. 3rd, Dokainish, H., Edvardsen, T., et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J. Am. Soc. Echocardiogr. 29 (2016), 277–314.
14. Lang, R.M., Badano, L.P., Mor-Avi, V., Afilalo, J., Armstrong, A., Ernande, L., et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J. Am. Soc. Echocardiogr. 28 (2015), 1–39 (e14).
15. Nagueh, S.F., Echocardiographic assessment of left ventricular relaxation and cardiac filling pressures. Curr. Heart Fail. Rep. 6 (2009), 154–159.
16. Paraskevaidis, I.A., Dodouras, T., Adamopoulos, S., Kremastinos, D.T., Left atrial functional reserve in patients with nonischemic dilated cardiomyopathy: an echocardiographic dobutamine study. Chest 122 (2002), 1340–1347.
17. Cameli, M., Mandoli, G.E., Loiacono, F., Dini, F.L., Henein, M., Mondillo, S., Left atrial strain: a new parameter for assessment of left ventricular filling pressure. Heart Fail. Rev. 21 (2016), 65–76.
18. Eicher, J.C., Berthier, S., Aho, L.S., Lorcerie, B., Bonnotte, B., Laurent, G., Measurement of interatrial dyssynchrony using tissue Doppler imaging predicts functional capacity and cardiac involvement in systemic sclerosis. Clin. Exp. Rheumatol., 32, 2014, S-171-6.
19. Dabrowska-Kugacka, A., Lewicka-Nowak, E., Rucinski, P., Zagozdzon, P., Raczak, G., Kutarski, A., Atrial electromechanical sequence and contraction synchrony during single- and multisite atrial pacing in patients with brady-tachycardia syndrome. Pacing Clin. Electrophysiol. 32 (2009), 591–603.
20. Melenovsky, V., Hwang, S.J., Redfield, M.M., Zakeri, R., Lin, G., Borlaug, B.A., Left atrial remodeling and function in advanced heart failure with preserved or reduced ejection fraction. Circ. Heart Fail. 8 (2015), 295–303.
21. Santos, A.B., Kraigher-Krainer, E., Gupta, D.K., Claggett, B., Zile, M.R., Pieske, B., et al. Impaired left atrial function in heart failure with preserved ejection fraction. Eur. J. Heart Fail. 16 (2014), 1096–1103.
22. Ho, S.Y., Sanchez-Quintana, D., Cabrera, J.A., Anderson, R.H., Anatomy of the left atrium: implications for radiofrequency ablation of atrial fibrillation. J. Cardiovasc. Electrophysiol. 10 (1999), 1525–1533.
23. Wan, S.H., Vogel, M.W., Chen, H.H., Pre-clinical diastolic dysfunction. J. Am. Coll. Cardiol. 63 (2014), 407–416.
24. Milliez, P., Deangelis, N., Rucker-Martin, C., Leenhardt, A., Vicaut, E., Robidel, E., et al. Spironolactone reduces fibrosis of dilated atria during heart failure in rats with myocardial infarction. Eur. Heart J. 26 (2005), 2193–2199.
25. Sakabe, K., Fukuda, N., Fukuda, Y., Morishita, S., Shinohara, H., Tamura, Y., Interatrial dyssynchrony on tissue Doppler imaging predicts progression to chronic atrial fibrillation in patients with non-valvular paroxysmal atrial fibrillation. Heart 95 (2009), 988–993.
26. Dabrowska-Kugacka, A., Lewicka-Nowak, E., Rucinski, P., Zagozdzon, P., Raczak, G., Kutarski, A., Relationship between P-wave duration and atrial electromechanical delay assessed by tissue Doppler echocardiography. Pacing Clin. Electrophysiol. 34 (2011), 23–31.
27. Manolis, A.G., Katsivas, A.G., Vassilopoulos, C., Koutsogeorgis, D., Louvros, N.E., Prevention of atrial fibrillation by inter-atrial septum pacing guided by electrophysiological testing, in patients with delayed interatrial conduction. Europace 4 (2002), 165–174.
28. Tan, Y.T., Wenzelburger, F., Lee, E., Heatlie, G., Leyva, F., Patel, K., et al. The pathophysiology of heart failure with normal ejection fraction: exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion. J. Am. Coll. Cardiol. 54 (2009), 36–46.
29. Zile, M.R., Baicu, C.F., Gaasch, W.H., Diastolic heart failure—abnormalities in active relaxation and passive stiffness of the left ventricle. N. Engl. J. Med. 350 (2004), 1953–1959.
30. Westermann, D., Kasner, M., Steendijk, P., Spillmann, F., Riad, A., Weitmann, K., et al. Role of left ventricular stiffness in heart failure with normal ejection fraction. Circulation 117 (2008), 2051–2060.
31. Kawaguchi, M., Hay, I., Fetics, B., Kass, D.A., Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: implications for systolic and diastolic reserve limitations. Circulation 107 (2003), 714–720.
32. Kelder, J.C., Cowie, M.R., McDonagh, T.A., Hardman, S.M., Grobbee, D.E., Cost, B., et al. Quantifying the added value of BNP in suspected heart failure in general practice: an individual patient data meta-analysis. Heart 97 (2011), 959–963.
33. Boyd, A.C., Ng, A.C., Tran da, T., Chia, E.M., French, J.K., Leung, D.Y., et al. Left atrial enlargement and phasic function in patients following non-ST elevation myocardial infarction. J. Am. Soc. Echocardiogr. 23 (2010), 1251–1258.