Evolution of a dominant natural isolate of Escherichia coli in the human gut over the course of a year suggests a neutral evolution with reduced effective population size

Applied and Environmental Microbiology

Volumn 84, Issue 6, 2018, Pages

  Ghalayini, Mohamed ^a,b,c   Launay, Adrien ^a,d   Bridier Nahmias, Antoine ^a,d   Clermont, Olivier ^a,d   Denamur, Erick ^a,c,d   Lescat, Mathilde ^a,b,c   Tenaillona, Olivier ^d  

^a UNIVERSITÉ PARIS DIDEROT   (France)

^b UNIVERSITÉ PARIS 13   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

ED1a; Escherichia coli; Human gut; Molecular evolution; Mutation rate; Neutral evolution; Replication rate

Indexed keywords

GENES; MOLECULAR BIOLOGY; POPULATION STATISTICS;

ED1A; HUMAN GUTS; MOLECULAR EVOLUTION; MUTATION RATES; NEUTRAL EVOLUTION;

ESCHERICHIA COLI;

CHROMOSOME; COLIFORM BACTERIUM; DIGESTIVE SYSTEM; EVOLUTIONARY BIOLOGY; EXPERIMENTAL STUDY; GENE; GENOMICS; MOLECULAR ANALYSIS; MUTATION; POPULATION SIZE; RECOMBINATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

ADAPTATION; BACTERIAL CHROMOSOME; BACTERIAL GENE; BIODIVERSITY; ESCHERICHIA COLI; FECES; GASTROINTESTINAL TRACT; GENETIC DRIFT; GENETIC VARIATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; MOLECULAR EVOLUTION; MUTATION; MUTATION RATE; POPULATION DENSITY; SYMBIOSIS;

ADAPTATION, PHYSIOLOGICAL; BIODIVERSITY; CHROMOSOMES, BACTERIAL; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; FECES; GASTROINTESTINAL TRACT; GENES, BACTERIAL; GENETIC DRIFT; GENETIC VARIATION; HUMANS; MUTATION; MUTATION RATE; POPULATION DENSITY; SYMBIOSIS;

EID: 85042660870     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.02377-17     Document Type: Article

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