Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging

New England Journal of Medicine

Volumn 378, Issue 8, 2018, Pages 708-718

  Albers, G W ^a   Marks, M P ^a   Kemp, S ^a   Christensen, S ^a   Tsai, J P ^a   Ortega Gutierrez, S ^a   McTaggart, R A ^a   Torbey, M T ^a   Kim Tenser, M ^a   Leslie Mazwi, T ^b   Sarraj, A ^a   Kasner, S E ^a   Ansari, S A ^a   Yeatts, S D ^c   Hamilton, S ^c   Mlynash, M ^d   Heit, J J ^e   Zaharchuk, G ^d   Kim, S ^f   Carrozzella, J ^k   Palesch, Y Y ^l   Demchuk, A M ^g   Bammer, R ^h   Lavori, P W ⁱ   Broderick, J P ^j   Lansberg, M G ^m   more..

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d BROWN UNIVERSITY   (United States)

^e OHIO STATE UNIVERSITY   (United States)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

^h UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

ⁱ UNIVERSITY OF PENNSYLVANIA   (United States)

^j NORTHWESTERN UNIVERSITY   (United States)

^k MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^l NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m UNIVERSITY OF CALGARY   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR; FIBRINOLYTIC AGENT;

ADULT; AGED; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN SCINTISCANNING; BRAIN SIZE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; HUMAN; INFORMED CONSENT; INTERNAL CAROTID ARTERY OCCLUSION; MAJOR CLINICAL STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MULTICENTER STUDY; OPEN STUDY; PERCUTANEOUS THROMBECTOMY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RANKIN SCALE; SURGICAL MORTALITY; TREATMENT OUTCOME; BRAIN ANGIOGRAPHY; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; DIAGNOSTIC IMAGING; ENDOVASCULAR SURGERY; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; SCINTIGRAPHY; SINGLE BLIND PROCEDURE; THROMBECTOMY; TIME TO TREATMENT;

AGED; BRAIN ISCHEMIA; CEREBRAL ANGIOGRAPHY; COMBINED MODALITY THERAPY; ENDOVASCULAR PROCEDURES; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MALE; MIDDLE AGED; PERFUSION IMAGING; SINGLE-BLIND METHOD; STROKE; THROMBECTOMY; TIME-TO-TREATMENT;

EID: 85042629779     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1713973     Document Type: Article

References (20)

1. Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a metaanalysis of individual patient data from five randomised trials. Lancet 2016;387:1723-31.
2. Powers WJ, Derdeyn CP, Biller J, et al. 2015 American Heart Association/American Stroke Association focused update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2015;46:3020-35.
3. Nogueira RG, Jadhav AP, Haussen DC, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med 2018;378:11-21.
4. Albers GW, Goyal M, Jahan R, et al. Ischemic core and hypoperfusion volumes predict infarct size in SWIFT PRIME. Ann Neurol 2016;79:76-89.
5. Wheeler HM, Mlynash M, Inoue M, et al. Early diffusion-weighted imaging and perfusion-weighted imaging lesion volumes forecast final infarct size in DEFUSE 2. Stroke 2013;44:681-5.
6. Lansberg MG, Straka M, Kemp S, et al. MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study. Lancet Neurol 2012;11:860-7.
7. Lansberg MG, Christensen S, Kemp S, et al. Computed tomographic perfusion to predict response to recanalization in ischemic stroke. Ann Neurol 2017;81:849-56.
8. Straka M, Albers GW, Bammer R. Real-time diffusion-perfusion mismatch analysis in acute stroke. J Magn Reson Imaging 2010;32:1024-37.
9. Albers GW, Lansberg MG, Kemp S, et al. A multicenter randomized controlled trial of endovascular therapy following imaging evaluation for ischemic stroke (DEFUSE 3). Int J Stroke 2017;12:896-905.
10. Jauch EC, Saver JL, Adams HP Jr, et al. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2013;44:870-947.
11. Zaidat OO, Yoo AJ, Khatri P, et al. Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke 2013;44:2650-63.
12. Lai TL, Lavori PW, Liao OY. Adaptive choice of patient subgroup for comparing two treatments. Contemp Clin Trials 2014;39:191-200.
13. Khatri P, Yeatts SD, Mazighi M, et al. Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the Interventional Management of Stroke (IMS III) phase 3 trial. Lancet Neurol 2014;13:567-74.
14. Saver JL, Goyal M, van der Lugt A, et al. Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA 2016;316:1279-88.
15. Fransen PS, Berkhemer OA, Lingsma HF, et al. Time to reperfusion and treatment effect for acute ischemic stroke: a randomized clinical trial. JAMA Neurol 2016;73:190-6.
16. Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372:1009-18.
17. Saver JL, Goyal M, Bonafe A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015;372:2285-95.
18. Albers GW, Goyal M, Jahan R, et al. Relationships between imaging assessments and outcomes in Solitaire with the Intention for Thrombectomy as Primary Endovascular Treatment for acute ischemic stroke. Stroke 2015;46:2786-94.
19. Wheeler HM, Mlynash M, Inoue M, et al. The growth rate of early DWI lesions is highly variable and associated with penumbral salvage and clinical outcomes following endovascular reperfusion. Int J Stroke 2015;10:723-9.
20. Federau C, Mlynash M, Christensen S, et al. Evolution of volume and signal intensity on fluid-attenuated inversion recovery MR images after endovascular stroke therapy. Radiology 2016;280:184-92.