The Opioid Crisis: a Comprehensive Overview

Current Pain and Headache Reports

Volumn 22, Issue 3, 2018, Pages

  Vadivelu, Nalini ^a   Kai, Alice M ^b   Kodumudi, Vijay ^c   Sramcik, Julie ^a   Kaye, Alan D ^d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WINTHROP UNIVERSITY HOSPITAL   (United States)

^c UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^d LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Health policy; Opioids; Overdose deaths; Pain

Indexed keywords

GABAPENTIN; OPIATE; OXYCODONE; OXYCODONE PLUS PARACETAMOL;

ANALGESIA; ARTICLE; CARDIOVASCULAR DISEASE; CHRONIC PAIN; DISEASE EXACERBATION; DRUG DEPENDENCE; DRUG FATALITY; DRUG INDUSTRY; DRUG OVERDOSE; DRUG UTILIZATION; ENDOCRINE DISEASE; EPIDEMIC; FRACTURE; HEALTH CARE ACCESS; HEALTH CARE COST; HEALTH CARE POLICY; HOSPITAL READMISSION; HUMAN; HYPERALGESIA; ILEUS; LENGTH OF STAY; MEDICAL SOCIETY; MEDICATION OVERUSE; NEONATAL ABSTINENCE SYNDROME; OPIATE ADDICTION; PAIN; PNEUMONIA; POSTOPERATIVE PAIN; PREGNANCY; PRESCRIPTION; PREVALENCE; MORTALITY; PRESCRIPTION DRUG MISUSE; STATISTICS AND NUMERICAL DATA; TRENDS; UNITED STATES;

CHRONIC PAIN; HUMANS; OPIOID-RELATED DISORDERS; PRESCRIPTION DRUG MISUSE; UNITED STATES;

EID: 85042540059     PISSN: 15313433     EISSN: 15343081     Source Type: Journal    
DOI: 10.1007/s11916-018-0670-z     Document Type: Article

References (41)

1. • Rudd RA. Increases in Drug and Opioid-Involved Overdose Deaths—United States, 2010–2015. MMWR Morbidity and Mortality Weekly Report. 2016;65. Death count report of opioid-related overdose deaths.
2. Rudd RA, Aleshire N, Zibbell JE, Matthew Gladden R. Increases in drug and opioid overdose deaths—United States, 2000–2014. Am J Transplant. 2016;16(4):1323–7. https://doi.org/10.1111/ajt.13776.
3. Jones CM. Trends in methadone distribution for pain treatment, methadone diversion, and overdose deaths—United States, 2002–2014. MMWR Morbidity and Mortality Weekly Report. 2016;65.
4. Gladden RM. Fentanyl law enforcement submissions and increases in synthetic opioid–involved overdose deaths—27 states, 2013–2014. MMWR Morbidity and Mortality Weekly Report. 2016;65.
5. Peterson AB. Increases in fentanyl-related overdose deaths—Florida and Ohio, 2013–2015. MMWR Morbidity and Mortality Weekly Report. 2016;65.
6. Clarke JL, Skoufalos A, Scranton R. The American opioid epidemic: population health implications and potential solutions. Report from the National Stakeholder Panel. Popul Health Manag. 2016;19(S1):S-1–S-10.
7. Policy SLoD. Harrison Narcotics Tax Act, 1914 [May 14, 2017]. Available from: http://www.druglibrary.org/schaffer/history/e1910/harrisonact.htm.
8. Weiner SG, Malek SK, Price CN. The opioid crisis and its consequences. Transplantation. 2017;101(4):678–81. https://doi.org/10.1097/TP.0000000000001671.
9. Declaration of Montreal 2010. (2017). Available from: http://www.iasp-pain.org/DeclarationofMontreal?
10. Meier B. Pain killer: A" wonder" drug's trail of addiction and death: Rodale; 2003.
11. Portenoy RK, Foley KM. Chronic use of opioid analgesics in non-malignant pain: report of 38 cases. Pain. 1986;25(2):171–86. https://doi.org/10.1016/0304-3959(86)90091-6.
12. Van Zee A. The promotion and marketing of oxycontin: commercial triumph, public health tragedy. Am J Public Health. 2009;99(2):221–7. https://doi.org/10.2105/AJPH.2007.131714.
13. Control CfD, Prevention. CDC grand rounds: prescription drug overdoses—a US epidemic. MMWR Morb Mortal Wkly Rep. 2012;61(1):10.
14. Lipton B CD, Robertson J. Workers Compensation prescription drug study: 2013 update. September 2013 [May 14, 2017]. Available from: https://www.ncci.com/Articles/Documents/II_Prescription_Drugs-2013.pdf.
15. Anderson KO, Green CR, Payne R. Racial and ethnic disparities in pain: causes and consequences of unequal care. J Pain. 2009;10(12):1187–204. https://doi.org/10.1016/j.jpain.2009.10.002.
16. Cintron A, Morrison RS. Pain and ethnicity in the United States: a systematic review. J Palliat Med. 2006;9(6):1454–73. https://doi.org/10.1089/jpm.2006.9.1454.
17. Meghani SH, Byun E, Gallagher RM. Time to take stock: a meta-analysis and systematic review of analgesic treatment disparities for pain in the United States. Pain Med. 2012;13(2):150–74. https://doi.org/10.1111/j.1526-4637.2011.01310.x.
18. Hwang U, Belland LK, Handel DA, Yadav K, Heard K, Rivera-Reyes L, et al. Is all pain is treated equally? A multicenter evaluation of acute pain care by age. Pain. 2014;155(12):2568–74. https://doi.org/10.1016/j.pain.2014.09.017.
19. Society AP. Principles of analgesic use in the treatment of acute pain and cancer pain: American Pain Society; 1999.
20. Frasco PE, Sprung J, Trentman TL. The impact of the joint commission for accreditation of healthcare organizations pain initiative on perioperative opiate consumption and recovery room length of stay. Anesth Analg. 2005;100(1):162–8. https://doi.org/10.1213/01.ANE.0000139354.26208.1C.
21. Rodgers J, Cunningham K, Fitzgerald K, Finnerty E. Opioid consumption following outpatient upper extremity surgery. J Hand Surg. 2012;37(4):645–50. https://doi.org/10.1016/j.jhsa.2012.01.035.
22. • Macintyre P, Huxtable C, Flint S, Dobbin M. Costs and consequences: a review of discharge opioid prescribing for ongoing management of acute pain. Anaesth Intensive Care. 2014;42(5):558–74. The consequences of opioid pain regimens for pain therapy.
23. Martin PR, Finlayson AR. Opioid use disorder during pregnancy in Tennessee: expediency vs. science. Am J Drug Alcohol Abuse. 2015;41(5):367–70. https://doi.org/10.3109/00952990.2015.1047502.
24. Cicero TJ, Ellis MS, Surratt HL, Kurtz SP. The changing face of heroin use in the United States: a retrospective analysis of the past 50 years. JAMA Psychiatry. 2014;71(7):821–6. https://doi.org/10.1001/jamapsychiatry.2014.366.
25. Manchikanti L, Singh A. Therapeutic opioids: a ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids. Pain Physician. 2008;11(2 Suppl):S63–88.
26. Bohnert AS, Ilgen MA, Trafton JA, Kerns RD, Eisenberg A, Ganoczy D, et al. Trends and regional variation in opioid overdose mortality among Veterans Health Administration patients, fiscal year 2001 to 2009. Clin J Pain. 2014;30(7):605–12. https://doi.org/10.1097/AJP.0000000000000011.
27. Seal KH, Shi Y, Cohen G, Cohen BE, Maguen S, Krebs EE, et al. Association of mental health disorders with prescription opioids and high-risk opioid use in US veterans of Iraq and Afghanistan. JAMA. 2012;307(9):940–7. https://doi.org/10.1001/jama.2012.234.
28. Veliz P, Epstein-Ngo QM, Meier E, Ross-Durow PL, McCabe SE, Boyd CJ. Painfully obvious: a longitudinal examination of medical use and misuse of opioid medication among adolescent sports participants. J Adolesc Health. 2014;54(3):333–40. https://doi.org/10.1016/j.jadohealth.2013.09.002.
29. Krans EE, Patrick SW. Opioid use disorder in pregnancy: health policy and practice in the midst of an epidemic. Obstet Gynecol. 2016;128(1):4–10. https://doi.org/10.1097/AOG.0000000000001446.
30. • Psaty BM, Merrill JO. Addressing the opioid epidemic—opportunities in the postmarketing setting. N Engl J Med. 2017;2017(376):1502–4. A review of the evolvement of the public policy surrounding opioid use and how it has shaped pain management.
31. Gan TJ, Robinson SB, Oderda GM, Scranton R, Pepin J, Ramamoorthy S. Impact of postsurgical opioid use and ileus on economic outcomes in gastrointestinal surgeries. Curr Med Res Opin. 2015;31(4):677–86. https://doi.org/10.1185/03007995.2015.1005833.
32. Oderda GM, Gan TJ, Johnson BH, Robinson SB. Effect of opioid-related adverse events on outcomes in selected surgical patients. J Pain Palliat Care Pharmacother. 2013;27(1):62–70. https://doi.org/10.3109/15360288.2012.751956.
33. Kessler ER, Shah M, Gruschkus KS, Raju A. Cost and quality implications of opioid-based postsurgical pain control using administrative claims data from a large health system: opioid-related adverse events and their impact on clinical and economic outcomes. Pharmacother J Hum Pharmacol Drug Ther. 2013;33(4):383–91. https://doi.org/10.1002/phar.1223.
34. Krashin D, Murinova N, Sullivan M. Challenges to treatment of chronic pain and addiction during the “opioid crisis”. Curr Pain Headache Rep. 2016;20(12):65. https://doi.org/10.1007/s11916-016-0596-2.
35. Martin BC, Fan M-Y, Edlund MJ, DeVries A, Braden JB, Sullivan MD. Long-term chronic opioid therapy discontinuation rates from the TROUP study. J Gen Intern Med. 2011;26(12):1450–7. https://doi.org/10.1007/s11606-011-1771-0.
36. Ailes EC, Dawson AL, Lind JN, Gilboa SM, Frey MT, Broussard CS, et al. Opioid prescription claims among women of reproductive age—United States, 2008-2012. MMWR Morb Mortal Wkly Rep. 2015;64(2):37–41.
37. Desai RJ, Hernandez-Diaz S, Bateman BT, Huybrechts KF. Increase in prescription opioid use during pregnancy among Medicaid-enrolled women. Obstet Gynecol. 2014;123(5):997–1002. https://doi.org/10.1097/AOG.0000000000000208.
38. Martin CE, Longinaker N, Terplan M. Recent trends in treatment admissions for prescription opioid abuse during pregnancy. J Subst Abus Treat. 2015;48(1):37–42. https://doi.org/10.1016/j.jsat.2014.07.007.
39. Patrick SW, Dudley J, Martin PR, Harrell FE, Warren MD, Hartmann KE, et al. Prescription opioid epidemic and infant outcomes. Pediatrics. 2015;135(5):842–50. https://doi.org/10.1542/peds.2014-3299.
40. Patrick SW, Davis MM, Lehmann CU, Cooper WO. Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012. J Perinatol. 2015;35(8):650–5. https://doi.org/10.1038/jp.2015.36.
41. • Murthy VH. Ending the opioid epidemic—a call to action. N Engl J Med. 2016;375(25):2413–5. https://doi.org/10.1056/NEJMp1612578. An appeal by the Office of the Surgeon General to the medical community to aid in America’s escalating opioid epidemic.