The American Opioid Epidemic: Population health implications and potential solutions. Report from the national stakeholder panel

Population Health Management

Volumn 19, Issue S1, 2016, Pages S1-S10

  Clarke, Janice L ^a   Skoufalos, Alexis ^a   Scranton, Richard ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b Pacira Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OPIATE; NARCOTIC ANALGESIC AGENT;

ANALGESIA; CHRONIC PAIN; DRUG MISUSE; DRUG OVERDOSE; EPIDEMIC; HOSPITAL COST; HUMAN; OPIATE ADDICTION; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE PAIN; PRESCRIPTION; REVIEW; RISK REDUCTION; SUBSTANCE ABUSE; SURGICAL PATIENT; UNITED STATES; ADVERSE EFFECTS; HEALTH CARE POLICY; MEDICAL SOCIETY; OPIOID-RELATED DISORDERS;

ANALGESICS, OPIOID; EPIDEMICS; HEALTH POLICY; HUMANS; OPIOID-RELATED DISORDERS; PAIN MANAGEMENT; SOCIETIES, MEDICAL; UNITED STATES;

EID: 84959213393     PISSN: 19427891     EISSN: 19427905     Source Type: Journal    
DOI: 10.1089/pop.2015.0144     Document Type: Review

References (68)

1. Centers for Disease Control and Prevention. Vital Signs: opioid painkiller prescribing. July 2014. http://www.cdc.gov/.vitalsigns/opioid-prescribing/. Accessed December. 7, 2015
2. Cullen KA, Hall MJ, Golosinsky A. Ambulatory surgery in the United States, 2006. Natl Health Stat Report. 2009; 11(11): 1-25
3. Alam A, Gomes T, Zheng H, Mamdami MM, Juurlink DN, Bell CM. Long-Term analgesic use after low-risk surgery: a: retrospective cohort study. Arch Intern Med. 2012; 172: 425-430
4. MacQuarrie B. Disparate states, a common horror. August. 8, 2015. https://www.bostonglobe.com/metro/2015/08/09/.kentucky-opioid-epidemic-has-warnings-lessons-for-massa chusetts/ZD90hbbr44Gt4pFfzNErwJ/story.html. Accessed December. 7, 2015
5. Substance Abuse and Mental Health Services Administration. Results from the 2012 National Survey on Drug Use and Health: Summary of National Findings. NSDUH Series H-46, HHS Publication No. (SMA) 13-4795. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2013
6. Volkow ND. America's addiction to opioids: heroin and prescription drug abuse. http://www.drugabuse.gov/about-nida/.legislative-Activities/testimony-To-congress/2015/americasaddiction-To-opioids-heroin-prescription-drug-Abuse. Accessed December. 28, 2015
7. Paulozzi LJ, Budnitz DS, Xi Y. Increasing deaths from opioid analgesics in the United States. Pharmacoepidemiol Drug Saf. 2006; 15: 618-627
8. Centers for Disease Control and Prevention. CDC Vital Signs. Opioid painkillers prescribing: where you live makes a difference. July 2014. http://www.cdc.gov/vitalsigns/opioidprescribing/. Accessed December. 28, 2015
9. Franklin GM. Opioids for chronic noncancer pain. Neurology. 2014; 83: 1277-1284
10. Centers for Disease Control and Prevention. Policy Impact: Prescription painkiller overdoses. November 2011. http://www .cdc.gov/homeandrecreationalsafety/rxbrief/. Accessed December. 7, 2015
11. The National Center on Addiction and Substance Abuse at Columbia University. National Survey of American Attitudes on Substance Abuse XIV: Teens and Parents. New York: CASA Columbia; August 2009
12. National Drug Intelligence Center; Drug Enforcement Administration; US Department of Justice. National Prescription Drug Threat Assessment. 2009. www.justice.gov/.archive/ndic/pubs33/33775/33775p.pdf. Accessed December. 4, 2014
13. Centers for Disease Control and Prevention. 2013 Drug Overdose Mortality Data Announced. January. 12, 2015. http://.www.cdc.gov/media/releases/2015/p0114-drug-overdose.html. Accessed December. 7, 2015
14. Volkow ND. What is the federal government doing to combat the opioid abuse epidemic?May. 1, 2015. http://www .drugabuse.gov/about-nida/legislative-Activities/testimony-Tocongress/.2015/what-federal-government-doing-To-combatopioid-Abuse-epidemic. Accessed December. 28, 2015
15. Edwards J. Yes, Bayer promoted heroin for children. Here are the ads that prove it. http://www.businessinsider.com/.yes-bayer-promoted-heroin-for-children-here-Are-The-Ads-Thatprove-it-2011-11?op=1#ixzz3dRLJqra2. Accessed September. 16, 2015
16. Schaffer Library of Drug Policy. Harrison Narcotics Tax Act, 1914. http://www.druglibrary.org/schaffer/history/.e1910/harrisonact.htm. Accessed December. 7, 2015
17. Federation of State Medical Boards. Model policy on the use of opioid analgesics in the treatment of chronic pain. July 2013. http://www.fsmb.org/Media/Default/PDF/FSMB/.Advocacy/pain-policy-july2013.pdf. Accessed December. 28, 2015
18. Lipton B, Colon D, Robertson J. Workers Compensation prescription drug study: 2013 update. September 2013. https://www.ncci.com/Articles/Documents/II-Prescription-.Drugs-2013.pdf. Accessed December. 28, 2015
19. Seal KH, Shi Y, Cohen G, et al. Association of mental health disorders with prescription opioids and high-risk opioid use in US veterans of Iraq and Afghanistan. JAMA. 2012; 307: 940-947
20. Bohnert ASB, Ilgen MA, Traftfon JA, et al. Trends and regional variations in opioid overdose mortality among Veterans Health Administration patients, fiscal year 2001 to 2009. Clin J Pain. 2014; 30: 605-612
21. American Pain Society. Principles of Analgesic Use in the Treatment of Acute Pain and Cancer Pain. 6th ed. Chicago, IL: American Pain Society; 2008
22. Frasco PE, Sprung J, Trentman TL. The impact of the Joint Commission for Accreditation of Healthcare Organization's pain initiative on perioperative opiate consumption and recovery room length of stay. J Anesth Analg. 2005; 100: 162-168
23. Will lessons learned from the decade of pain control drive better outcomes in pain management?. Painweek.org. http://.www.painweek.org/brainfood-post/will-lessons-learnedfrom-The-decade-of-pain-control-drive-better-outcomes-inpain-management/. Accessed September. 16, 2015
24. Apfelbaum JL, Chen C, Mehta SS, Gan TJ. Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged. Anesth Analg. 2003; 97: 534-540
25. American Society of Anesthesiologists Task Force on Acute Pain Management. Practice guidelines for acute pain management in the perioperative setting: an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Managemen. Anesthesiology. 2004; 100: 1573-1581
26. Perkins FM, Kehlet, H. Chronic pain as an outcome of surgery: a review of predictive factors. Anesthesiology. 2000; 93: 1123-1133
27. Substance Abuse and Mental Health Services Administration. Results from the 2009 National Survey on Drug Use and Health. Volume 1: Summary of National Findings. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2010
28. Macintyre PE, Huxtable CA, Flint SL, Dobbin MD. Costs and consequences: a review of discharge opioid prescribing for ongoing management of acute pain. Anaesth Intensive Care. 2014; 42: 558-574
29. Rodgers J, Cunningham K, Fitzgerald K, Finnerty E. Opioid consumption following outpatient upper extremity surgery. J Hand Surg Am. 2012; 37: 645-650
30. Veliz P, Epstein-Ngo, QM, Meier E, Ross-Durow PL, McCabe SE, Boyd CJ. Painfully obvious: a longitudinal examination of medical use and misuse of opioid medications among adolescent sports participants. J Adolesc Health. 2014; 54: 333-340
31. Furlan AD, Chaparro LE, Irvin E, Mallis-Gagnon A. A comparison between enriched and nonenriched enrollment randomized withdrawal trials of opioids for chronic noncancer pain. Pain Res Manag. 2011; 16: 337-351
32. Noble M, Treadwell JR, Tregear SJ, et al. Long-Term opioid management for chronic noncancer pain. Cochrane Database Syst Rev. 2010; (1): CD006605
33. Singh JA, Lewallen D. Predictors of pain and use of pain medications following primary total hip arthroplasty (THA): 5, 707 THAs at 2-years and 3, 289 THAs at 5-years. BMC Musculoskelet Disord. 2010; 11: 90
34. Carroll I, Barelka P, Wang CK, et al. A pilot cohort study of the determinants of longitudinal opioid use after surgery. Anesth Analg. 2012; 115: 694-702
35. Institute of Medicine. Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education and Research. https://www.iom.edu/./media/Files/Report% 20Files/2011/Relieving-Pain-in-America-A-Blueprint-for-Transforming-Prevention-Care-Education-Research/Pain% 20Research%202011%20Report%20Brief.pdf. Accessed June. 18, 2015
36. The Joint Commission. Revisions to pain management standard effective January. 1, 2015. http://www.jointcommission.org/assets/1/23/jconline-November-12 14.pdf. Accessed November. 19, 2014
37. The Joint Commission. Sentinel Event Alert: Safe Use of Opioids in Hospitals. Oakbrook Terrace, IL: The Joint Commission; 2012
38. U.S. Department of Health and Human Services, Office of Disease Prevention and Health Promotion. National Action Plan for Adverse Drug Event Prevention. Washington, DC: US Department of Health and Human Services; 2014
39. Lennon F, Moss J, Singleton P. The l-opioid receptor in cancer progression: is there a direct effect?. Anesthesiology. 2012; 116(4): 940-945
40. Carr DB, Reines HD, Schaffer J, Polomano RC, Lande S. The impact of technology on the analgesic gap and quality of acute pain management. Reg Anesth Pain Med. 2005; 30: 286-91
41. Kessler R, Shah M, Gruschkus SK, Raju A. Cost and quality implications of opioid-based post-surgical pain control using administrative claims data from a large health system: opioid-related adverse events and their impact on clinical and economic outcomes. Pharmacother. 2013; 33: 383-391
42. Chantler C. The role and education of doctors in the delivery of health care. Lancet. 1999; 353: 1178-1181
43. Association for the Advancement of Medical Instrumentation; Food and Drug Administration. Infusing patients safely: priority issues from the AAMI/FDA infusion device summit. October, 2010. http://s3.amazonaws.com/rdcmsaami/.files/production/public/FileDownloads/Summits/AAMI-.FDA-Summit-Report.pdf. Accessed May. 11, 2014
44. Meissner B, Nelson W, Hicks R, Sikirica V, Gagne J, Schein J. The rate and costs attributable to intravenous patient-controlled analgesia errors. Hospital Pharmacy. 2009; 44: 312-324
45. Miaskowski C. Patient-controlled modalities for acute postoperative pain management. J Perianesth Nurs. 2005; 20: 255-267
46. American Society of Anesthesiologists Task Force on Acute Pain Management. Practice guidelines for acute pain management in the perioperative setting: an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management. Anesthesiology. 2012; 116: 248-273
47. Wells N, Pasero C, McCaffery M. Improving the quality of care through pain assessment and management. In: Hughes RG, ed. Patient Safety and Quality: An Evidence-Based Handbook for Nurses. AHRQ publication No. 80-0043. Rockville, MD: Agency for Healthcare Research and Quality; 2008
48. Centers for Medicare & Medicaid Services. HCAHPS: Patients' perspectives of care survey. http://www.cms.gov/.Medicare/Quality-Initiatives-Patient-Assessment-Instruments/.HospitalQualityInits/HospitalHCAHPS.html. Accessed May. 11, 2015
49. Fenton JJ, Jerant AF, Bertakis KD, Franks P. The cost of satisfaction: a national study of patient satisfaction, health care utilization, expenditures, and mortality. Arch Intern Med. 2012; 172: 405-411
50. Farag E, Ghobrial M, Sessler DI, et al. Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex spine surgery. Anesthesiology. 2013; 119: 932-940
51. Buvanendran A, Kroin JS, Della Valle CJ, Kari M, Moric M, Tuman KJ. Perioperative oral pregabalin reduces chronic pain after total knee arthroplasty: a prospective, randomized, controlled trial. Anesth Analg. 2010; 110: 199-207
52. Burke SM, Shorten GD. Perioperative pregabalin improves pain and functional outcomes 3 months after lumbar discectomy. Anesth Analg. 2010; 110: 1180-0085
53. Kim JC, Choi YS, Kim KN, Shim JK, Lee JY, Kwak YL. Effective dose of peri-operative oral pregabalin as an adjunct to multimodal analgesic regimen in lumbar spinal fusion surgery. Spine. 2011; 36: 428-433
54. Singla N, Rock A, Pavliv L. A multi-center, randomized, double-blinded, placebo-controlled trial of intravenous ibuprofen (IV-ibuprofen) for the treatment of pain in postoperative orthopedic adult patients. Pain Med. 2010; 11: 1284-1293
55. Loftus R, Yeager MP, Clark JA, et al. Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery. Anesthesiology. 2010: 113: 639-646
56. Angst M, Clarke DJ. Ketamine for managing perioperative pain in opioid-dependent patients with chronic pain: a unique indicator?. Anesthesiology. 2010; 113: 514-515
57. Domino EF. Taming the ketamine tiger. Anesthesiology. 2010; 113: 678-686
58. Viscusi ER. Liposomal drug delivery for postoperative pain management. Reg Anesth Pain Med. 2005; 30: 491-496
59. Bottros MM, Christo PJ. Current perspectives on intrathecal drug delivery. J Pain Res. 2014; 7: 615-626
60. Haas E, Onel E, Miller H, Rgupathi M, White PF. A double-blinded, randomized, active-controlled study for post-hemorrhoidectomy pain management with liposome bupivacaine, a novel local analgesic formulation. Am Surg. 2012; 78: 574-581
61. Skolnick A, Thacker J, Lee L, et al. Liposomal bupivacaine improves outcomes in ileostomy reversal surgery and may be effective in more complex enhanced recovery procedures. Paper presented at: World Congress of Enhanced Recovery after Surgery and Perioperative Medicine; May. 10, 2015; Washington, DC
62. Abdelsattar JM, Boughey JC, Mohan AT, et al. Comparative study of liposomal bupivacaine versus paravertebral block for pain control following mastectomy with immediate tissue expander reconstruction. Paper presented at: Plastic Surgery Research Council 60th Annual Meeting, May 14-16, 2015; Seattle, Washington
63. Asche C, Kirkness C. Evaluating clinical and economic outcomes associated with liposomal bupivacaine for postsurgical pain following total knee arthroplasty. Paper presented at: ISPOR 20th Annual Meeting; May 16-20, 2015; Philadelphia, Pennsylvania
64. Killoran A, Kelly MP. Evidence-Based Public Health: Effectiveness and Efficiency. Oxford, United Kingdom: Oxford University Press; 2009: 160
65. Rice JB, Kirson NY, Shei A, et al. The economic burden of diagnosed opioid abuse among commercially insured individuals. Postgrad Med. 2014; 126(4): 53-58
66. Odera GM, Gan TJ, Johnson BH, Robinson SB. Effect of opioid-related adverse events on outcomes in selected surgical patients. J Pain Palliat Care Pharmacother. 2013; 27(1): 62-70
67. Gan TJ, Robinson SB, Oderda GM, Scranton R, Pepin J, Ramamoorthy S. Impact of postsurgical opioid use and ileus on economic outcomes in gastrointestinal surgeries. Curr Med Res Opin. 2015; 31: 677-686
68. Birnbaum HG, White AG, Schiller BA, Waldman T, Cleveland JM, Roland CL. Societal costs of prescription opioid abuse, dependence and misuse in the United States. Pain Med. 2011; 12: 657-667