메뉴 건너뛰기




Volumn 47, Issue 2, 2018, Pages 72-83

Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell?

Author keywords

Chronic kidney disease; Hemodialysis; Hepcidin; Iron; Iron overload; Iron storage disorder; Transferrin

Indexed keywords

FERRITIN; IRON; TRACE ELEMENT;

EID: 85042083271     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000486968     Document Type: Article
Times cited : (60)

References (82)
  • 3
    • 2042546096 scopus 로고    scopus 로고
    • Balancing acts: Molecular control of mammalian iron metabolism
    • Hentze MW, Muckenthaler MU, Andrews NC: Balancing acts: molecular control of mammalian iron metabolism. Cell 2004; 117: 285-297.
    • (2004) Cell , vol.117 , pp. 285-297
    • Hentze, M.W.1    Muckenthaler, M.U.2    Andrews, N.C.3
  • 4
    • 84973130364 scopus 로고    scopus 로고
    • Iron management in chronic kidney disease: Conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) controversies conference
    • Macdougall IC, Bircher AJ, Eckardt KU, et al: Iron management in chronic kidney disease: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) controversies conference. Kidney Int 2016; 89: 28-39.
    • (2016) Kidney Int , vol.89 , pp. 28-39
    • Macdougall, I.C.1    Bircher, A.J.2    Eckardt, K.U.3
  • 5
    • 33846650973 scopus 로고    scopus 로고
    • Molecular control of iron transport
    • Ganz T: Molecular control of iron transport. J Am Soc Nephrol 2007; 18: 394-400.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 394-400
    • Ganz, T.1
  • 6
    • 33748581212 scopus 로고    scopus 로고
    • Hepcidin-the iron regulatory hormone
    • Rossi E: Hepcidin-the iron regulatory hormone. Clin Biochem Rev 2005; 26: 47-49.
    • (2005) Clin Biochem Rev , vol.26 , pp. 47-49
    • Rossi, E.1
  • 7
    • 84962658729 scopus 로고    scopus 로고
    • Iron balance and the role of hepcidin in chronic kidney disease
    • Ganz T, Nemeth E: Iron balance and the role of hepcidin in chronic kidney disease. Semin Nephrol 2016; 36: 87-93.
    • (2016) Semin Nephrol , vol.36 , pp. 87-93
    • Ganz, T.1    Nemeth, E.2
  • 8
    • 85011308989 scopus 로고    scopus 로고
    • Regulation of the iron homeostatic hormone hepcidin
    • Sangkhae V, Nemeth E: Regulation of the iron homeostatic hormone hepcidin. Adv Nutr 2017; 8: 126-136.
    • (2017) Adv Nutr , vol.8 , pp. 126-136
    • Sangkhae, V.1    Nemeth, E.2
  • 9
    • 84931578381 scopus 로고    scopus 로고
    • Estimating tissue iron burden: Current status and future prospects
    • Wood JC: Estimating tissue iron burden: current status and future prospects. Br J Haematol 2015; 170: 15-28.
    • (2015) Br J Haematol , vol.170 , pp. 15-28
    • Wood, J.C.1
  • 10
    • 84995480815 scopus 로고    scopus 로고
    • Effects of intravenous iron on fibroblast growth factor 23 (FGF23) in haemodialysis patients: A randomized controlled trial
    • Roberts MA, Huang L, Lee D, et al: Effects of intravenous iron on fibroblast growth factor 23 (FGF23) in haemodialysis patients: a randomized controlled trial. BMC Nephrol 2016; 17: 177.
    • (2016) BMC Nephrol , vol.17 , pp. 177
    • Roberts, M.A.1    Huang, L.2    Lee, D.3
  • 11
    • 84903578007 scopus 로고    scopus 로고
    • Identification of erythroferrone as an erythroid regulator of iron metabolism
    • Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T: Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet 2014; 46: 678-684.
    • (2014) Nat Genet , vol.46 , pp. 678-684
    • Kautz, L.1    Jung, G.2    Valore, E.V.3    Rivella, S.4    Nemeth, E.5    Ganz, T.6
  • 13
    • 84879458253 scopus 로고    scopus 로고
    • Iron homeostasis in the liver
    • Anderson ER, Shah YM: Iron homeostasis in the liver. Compr Physiol 2013; 3: 315-330.
    • (2013) Compr Physiol , vol.3 , pp. 315-330
    • Anderson, E.R.1    Shah, Y.M.2
  • 17
    • 0015236945 scopus 로고
    • Iatrogenic contribution to anaemia of chronic renal failure
    • Hocken AG, Marwah PK: Iatrogenic contribution to anaemia of chronic renal failure. Lancet 1971; 1: 164-165.
    • (1971) Lancet , vol.1 , pp. 164-165
    • Hocken, A.G.1    Marwah, P.K.2
  • 18
    • 0942268189 scopus 로고    scopus 로고
    • Iron requirements in hemodialysis
    • Sargent JA, Acchiardo SR: Iron requirements in hemodialysis. Blood Purif 2004; 22: 112-123.
    • (2004) Blood Purif , vol.22 , pp. 112-123
    • Sargent, J.A.1    Acchiardo, S.R.2
  • 21
    • 60349120822 scopus 로고    scopus 로고
    • Intravenous iron versus erythropoiesis-stimulating agents: Friends or foes in treating chronic kidney disease anemia
    • Kalantar-Zadeh K, Streja E, Miller JE, Nissenson AR: Intravenous iron versus erythropoiesis-stimulating agents: friends or foes in treating chronic kidney disease anemia? Adv Chronic Kidney Dis 2009; 16: 143-151.
    • (2009) Adv Chronic Kidney Dis , vol.16 , pp. 143-151
    • Kalantar-Zadeh, K.1    Streja, E.2    Miller, J.E.3    Nissenson, A.R.4
  • 22
    • 84995677751 scopus 로고    scopus 로고
    • What are the considerations in balancing benefits and risks in iron treatment?: The benefits of intravenous iron
    • Wish JB: What are the considerations in balancing benefits and risks in iron treatment?: the benefits of intravenous iron. Semin Dial 2017; 30: 20-22.
    • (2017) Semin Dial , vol.30 , pp. 20-22
    • Wish, J.B.1
  • 23
    • 84958865798 scopus 로고    scopus 로고
    • A proton pump inhibitor a day keeps the iron away
    • Handa P, Kowdley KV: A proton pump inhibitor a day keeps the iron away. Clin Gastroenterol Hepatol 2016; 14: 153-155.
    • (2016) Clin Gastroenterol Hepatol , vol.14 , pp. 153-155
    • Handa, P.1    Kowdley, K.V.2
  • 24
    • 85044072408 scopus 로고    scopus 로고
    • Iron deficiency anemia due to the long-term use of a proton pump inhibitor
    • Epub ahead of print
    • Imai R, Higuchi T, Morimoto M, Koyamada R, Okada S: Iron deficiency anemia due to the long-term use of a proton pump inhibitor. Intern Med 2017, Epub ahead of print.
    • (2017) Intern Med
    • Imai, R.1    Higuchi, T.2    Morimoto, M.3    Koyamada, R.4    Okada, S.5
  • 25
    • 69249208830 scopus 로고    scopus 로고
    • Hepcidin-a potential novel biomarker for iron status in chronic kidney disease
    • Zaritsky J, Young B, Wang HJ, et al: Hepcidin-a potential novel biomarker for iron status in chronic kidney disease. Clin J Am Soc Nephrol 2009; 4: 1051-1056.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 1051-1056
    • Zaritsky, J.1    Young, B.2    Wang, H.J.3
  • 26
    • 77953307194 scopus 로고    scopus 로고
    • Reduction of serum hepcidin by hemodialysis in pediatric and adult patients
    • Zaritsky J, Young B, Gales B, et al: Reduction of serum hepcidin by hemodialysis in pediatric and adult patients. Clin J Am Soc Nephrol 2010; 5: 1010-1014.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 1010-1014
    • Zaritsky, J.1    Young, B.2    Gales, B.3
  • 27
    • 84896733066 scopus 로고    scopus 로고
    • The iron cycle in chronic kidney disease (CKD): From genetics and experimental models to CKD patients
    • Zumbrennen-Bullough K, Babitt JL: The iron cycle in chronic kidney disease (CKD): from genetics and experimental models to CKD patients. Nephrol Dial Transplant 2014; 29: 263-273.
    • (2014) Nephrol Dial Transplant , vol.29 , pp. 263-273
    • Zumbrennen-Bullough, K.1    Babitt, J.L.2
  • 28
    • 64049119384 scopus 로고    scopus 로고
    • Iron indices in chronic kidney disease in the National Health and Nutritional Examination Survey 1988-2004
    • Fishbane S, Pollack S, Feldman HI, Joffe MM: Iron indices in chronic kidney disease in the National Health and Nutritional Examination Survey 1988-2004. Clin J Am Soc Nephrol 2009; 4: 57-61.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 57-61
    • Fishbane, S.1    Pollack, S.2    Feldman, H.I.3    Joffe, M.M.4
  • 29
    • 77949559450 scopus 로고    scopus 로고
    • Bone marrow iron, iron indices, and the response to intravenous iron in patients with non-dialysis-dependent CKD
    • Stancu S, Stanciu A, Zugravu A, et al: Bone marrow iron, iron indices, and the response to intravenous iron in patients with non-dialysis-dependent CKD. Am J Kidney Dis 2010; 55: 639-647.
    • (2010) Am J Kidney Dis , vol.55 , pp. 639-647
    • Stancu, S.1    Stanciu, A.2    Zugravu, A.3
  • 31
    • 33846702712 scopus 로고    scopus 로고
    • Assessing iron status: Beyond serum ferritin and transferrin saturation
    • Wish JB: Assessing iron status: beyond serum ferritin and transferrin saturation. Clin J Am Soc Nephrol 2006; 1(suppl 1):S4-S8.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. S4-S8
    • Wish, J.B.1
  • 32
    • 84884333035 scopus 로고    scopus 로고
    • Improving Global Outcomes (KDIGO) Anemia Work Group: KDIGO clinical practice guideline for anemia in chronic kidney disease
    • Kidney Disease
    • Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group: KDIGO clinical practice guideline for anemia in chronic kidney disease. Kidney Int Suppl 2012; 2: 279-335.
    • (2012) Kidney Int Suppl , vol.2 , pp. 279-335
  • 33
    • 84879836673 scopus 로고    scopus 로고
    • Kidney Disease: Improving Global Outcomes guidelines on anaemia management in chronic kidney disease: A European renal best practice position statement
    • Locatelli F, Barany P, Covic A, et al: Kidney Disease: Improving Global Outcomes guidelines on anaemia management in chronic kidney disease: a European renal best practice position statement. Nephrol Dial Transplant 2013; 28: 1346-1359.
    • (2013) Nephrol Dial Transplant , vol.28 , pp. 1346-1359
    • Locatelli, F.1    Barany, P.2    Covic, A.3
  • 34
    • 84886727039 scopus 로고    scopus 로고
    • KDOQI US commentary on the 2012 KDIGO clinical practice guideline for anemia in CKD
    • Kliger AS, Foley RN, Goldfarb DS, et al: KDOQI US commentary on the 2012 KDIGO clinical practice guideline for anemia in CKD. Am J Kidney Dis 2013; 62: 849-859.
    • (2013) Am J Kidney Dis , vol.62 , pp. 849-859
    • Kliger, A.S.1    Foley, R.N.2    Goldfarb, D.S.3
  • 35
    • 84886718491 scopus 로고    scopus 로고
    • Canadian society of nephrology commentary on the 2012 KDIGO clinical practice guideline for anemia in CKD
    • Moist LM, Troyanov S, White CT, et al: Canadian society of nephrology commentary on the 2012 KDIGO clinical practice guideline for anemia in CKD. Am J Kidney Dis 2013; 62: 860-873.
    • (2013) Am J Kidney Dis , vol.62 , pp. 860-873
    • Moist, L.M.1    Troyanov, S.2    White, C.T.3
  • 36
    • 84936804415 scopus 로고    scopus 로고
    • Management of anaemia in chronic kidney disease: Summary of updated NICE guidance
    • Padhi S, Glen J, Pordes BA, Thomas ME: Management of anaemia in chronic kidney disease: summary of updated NICE guidance. BMJ 2015; 350:h2258.
    • (2015) BMJ , vol.350 , pp. h2258
    • Padhi, S.1    Glen, J.2    Pordes, B.A.3    Thomas, M.E.4
  • 37
    • 65349151448 scopus 로고    scopus 로고
    • The importance of iron in long-term survival of maintenance hemodialysis patients treated with epoetin-alfa and intravenous iron: Analysis of 9 5 years of prospectively collected data
    • Pollak VE, Lorch JA, Shukla R, Satwah S: The importance of iron in long-term survival of maintenance hemodialysis patients treated with epoetin-alfa and intravenous iron: analysis of 9. 5 years of prospectively collected data. BMC Nephrol 2009; 10: 6.
    • (2009) BMC Nephrol , vol.10 , pp. 6
    • Pollak, V.E.1    Lorch, J.A.2    Shukla, R.3    Satwah, S.4
  • 38
    • 85044076344 scopus 로고    scopus 로고
    • US-DOPPS (Dialysis and Advanced CKD Outcomes and Practice Patterns Study Program) Practice Monitor. Serum ferritin (3 month average), continuous (ng/mL). December, 2016. (accessed February 10, 2017)
    • US-DOPPS (Dialysis and Advanced CKD Outcomes and Practice Patterns Study Program) Practice Monitor. Serum ferritin (3 month average), continuous (ng/mL). December, 2016. http://www. dopps. org/DPM/ Files/meanferritinngml1-overallTAB. htm (accessed February 10, 2017).
  • 39
    • 84943786773 scopus 로고    scopus 로고
    • Understanding the recent increase in ferritin levels in United States dialysis patients: Potential impact of changes in intravenous iron and erythropoiesis-stimulating agent dosing
    • Karaboyas A, Zee J, Morgenstern H, et al: Understanding the recent increase in ferritin levels in United States dialysis patients: potential impact of changes in intravenous iron and erythropoiesis-stimulating agent dosing. Clin J Am Soc Nephrol 2015; 10: 1814-1821.
    • (2015) Clin J Am Soc Nephrol , vol.10 , pp. 1814-1821
    • Karaboyas, A.1    Zee, J.2    Morgenstern, H.3
  • 40
    • 84920107364 scopus 로고    scopus 로고
    • Data from the Dialysis Outcomes and Practice Patterns Study validate an association between high intravenous iron doses and mortality
    • Bailie GR, Larkina M, Goodkin DA, et al: Data from the Dialysis Outcomes and Practice Patterns Study validate an association between high intravenous iron doses and mortality. Kidney Int 2015; 87: 162-168.
    • (2015) Kidney Int , vol.87 , pp. 162-168
    • Bailie, G.R.1    Larkina, M.2    Goodkin, D.A.3
  • 42
    • 84890012992 scopus 로고    scopus 로고
    • Iron indices and survival in maintenance hemodialysis patients with and without polycystic kidney disease
    • Hatamizadeh P, Ravel V, Lukowsky LR, et al: Iron indices and survival in maintenance hemodialysis patients with and without polycystic kidney disease. Nephrol Dial Transplant 2013; 28: 2889-2898.
    • (2013) Nephrol Dial Transplant , vol.28 , pp. 2889-2898
    • Hatamizadeh, P.1    Ravel, V.2    Lukowsky, L.R.3
  • 43
    • 84870841812 scopus 로고    scopus 로고
    • Intravenous ferric chloride hexahydrate supplementation induced endothelial dysfunction and increased cardiovascular risk among hemodialysis patients
    • Kuo KL, Hung SC, Lin YP, et al: Intravenous ferric chloride hexahydrate supplementation induced endothelial dysfunction and increased cardiovascular risk among hemodialysis patients. PLoS One 2012; 7:e50295.
    • (2012) PLoS One , vol.7 , pp. e50295
    • Kuo, K.L.1    Hung, S.C.2    Lin, Y.P.3
  • 44
    • 84926225569 scopus 로고    scopus 로고
    • Association between hemoglobin variability, serum ferritin levels, and adverse events/mortality in maintenance hemodialysis patients
    • Kuragano T, Matsumura O, Matsuda A, et al: Association between hemoglobin variability, serum ferritin levels, and adverse events/mortality in maintenance hemodialysis patients. Kidney Int 2014; 86: 845-854.
    • (2014) Kidney Int , vol.86 , pp. 845-854
    • Kuragano, T.1    Matsumura, O.2    Matsuda, A.3
  • 45
    • 2542429341 scopus 로고    scopus 로고
    • Administration of parenteral iron and mortality among hemodialysis patients
    • Feldman HI, Joffe M, Robinson B, et al: Administration of parenteral iron and mortality among hemodialysis patients. J Am Soc Nephrol 2004; 15: 1623-1632.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1623-1632
    • Feldman, H.I.1    Joffe, M.2    Robinson, B.3
  • 46
    • 84926442768 scopus 로고    scopus 로고
    • Intravenous iron exposure and mortality in patients on hemodialysis
    • Miskulin DC, Tangri N, Bandeen-Roche K, et al: Intravenous iron exposure and mortality in patients on hemodialysis. Clin J Am Soc Nephrol 2014; 9: 1930-1939.
    • (2014) Clin J Am Soc Nephrol , vol.9 , pp. 1930-1939
    • Miskulin, D.C.1    Tangri, N.2    Bandeen-Roche, K.3
  • 47
    • 84942990469 scopus 로고    scopus 로고
    • A randomized trial of intravenous and oral iron in chronic kidney disease
    • Agarwal R, Kusek JW, Pappas MK: A randomized trial of intravenous and oral iron in chronic kidney disease. Kidney Int 2015; 88: 905-914.
    • (2015) Kidney Int , vol.88 , pp. 905-914
    • Agarwal, R.1    Kusek, J.W.2    Pappas, M.K.3
  • 48
    • 84916928192 scopus 로고    scopus 로고
    • FIND-CKD: A randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia
    • Macdougall IC, Bock AH, Carrera F, et al: FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia. Nephrol Dial Transplant 2014; 29: 2075-2084.
    • (2014) Nephrol Dial Transplant , vol.29 , pp. 2075-2084
    • Macdougall, I.C.1    Bock, A.H.2    Carrera, F.3
  • 49
    • 85018014099 scopus 로고    scopus 로고
    • Safety of intravenous ferric carboxymaltose versus oral iron in patients with nondialysis-dependent CKD: An analysis of the 1-year FINDCKD trial
    • Roger SD, Gaillard CA, Bock AH, et al: Safety of intravenous ferric carboxymaltose versus oral iron in patients with nondialysis-dependent CKD: an analysis of the 1-year FINDCKD trial. Nephrol Dial Transplant 2017; 32: 1530-1539.
    • (2017) Nephrol Dial Transplant , vol.32 , pp. 1530-1539
    • Roger, S.D.1    Gaillard, C.A.2    Bock, A.H.3
  • 50
    • 85042714231 scopus 로고    scopus 로고
    • Intravenous iron therapy in patients with chronic kidney disease: Recent evidence and future directions
    • Macdougall IC: Intravenous iron therapy in patients with chronic kidney disease: recent evidence and future directions. Clin Kidney J 2017; 10(suppl 1):i16-i24.
    • (2017) Clin Kidney J , vol.10 , pp. i16-i24
    • Macdougall, I.C.1
  • 51
    • 84942889564 scopus 로고    scopus 로고
    • Oral or intravenous iron for anemia correction in chronic kidney disease
    • Drueke TB, Massy ZA: Oral or intravenous iron for anemia correction in chronic kidney disease? Kidney Int 2015; 88: 673-675.
    • (2015) Kidney Int , vol.88 , pp. 673-675
    • Drueke, T.B.1    Massy, Z.A.2
  • 53
    • 39049101651 scopus 로고    scopus 로고
    • Ferric gluconate reduces epoetin requirements in hemodialysis patients with elevated ferritin
    • Kapoian T, O'Mara NB, Singh AK, et al: Ferric gluconate reduces epoetin requirements in hemodialysis patients with elevated ferritin. J Am Soc Nephrol 2008; 19: 372-379.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 372-379
    • Kapoian, T.1    O'Mara, N.B.2    Singh, A.K.3
  • 54
    • 33947212276 scopus 로고    scopus 로고
    • Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: Results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) study
    • Coyne DW, Kapoian T, Suki W, et al: Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) study. J Am Soc Nephrol 2007; 18: 975-984.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 975-984
    • Coyne, D.W.1    Kapoian, T.2    Suki, W.3
  • 55
    • 84969506829 scopus 로고    scopus 로고
    • Balance of benefit and risk in intravenous iron treatment in chronic kidney disease
    • Fishbane S: Balance of benefit and risk in intravenous iron treatment in chronic kidney disease. Semin Nephrol 2016; 36: 119-123.
    • (2016) Semin Nephrol , vol.36 , pp. 119-123
    • Fishbane, S.1
  • 56
    • 85010366264 scopus 로고    scopus 로고
    • Ferritin levels and risk of heart failure-the atherosclerosis risk in communities study
    • Silvestre OM, Goncalves A, Nadruz W Jr, et al: Ferritin levels and risk of heart failure-the atherosclerosis risk in communities study. Eur J Heart Fail 2017; 19: 340-347.
    • (2017) Eur J Heart Fail , vol.19 , pp. 340-347
    • Silvestre, O.M.1    Goncalves, A.2    Nadruz, W.3
  • 58
    • 34248337416 scopus 로고    scopus 로고
    • Iron overload syndromes and the liver
    • Batts KP: Iron overload syndromes and the liver. Mod Pathol 2007; 20(suppl 1):S31-S39.
    • (2007) Mod Pathol , vol.20 , pp. S31-S39
    • Batts, K.P.1
  • 59
    • 84977555036 scopus 로고    scopus 로고
    • The role of iron and iron overload in chronic liver disease
    • Milic S, Mikolasevic I, Orlic L, et al: The role of iron and iron overload in chronic liver disease. Med Sci Monit 2016; 22: 2144-2151.
    • (2016) Med Sci Monit , vol.22 , pp. 2144-2151
    • Milic, S.1    Mikolasevic, I.2    Orlic, L.3
  • 60
    • 84969567616 scopus 로고    scopus 로고
    • Iron treatment strategies in dialysis-dependent CKD
    • Pandey R, Daloul R, Coyne DW: Iron treatment strategies in dialysis-dependent CKD. Semin Nephrol 2016; 36: 105-111.
    • (2016) Semin Nephrol , vol.36 , pp. 105-111
    • Pandey, R.1    Daloul, R.2    Coyne, D.W.3
  • 61
    • 70349785761 scopus 로고    scopus 로고
    • A field guide to iron needs in the patient on hemodialysis
    • 396-403
    • Wick G: A field guide to iron needs in the patient on hemodialysis. Nephrol Nurs J 2009; 36: 389-392, 396-403.
    • (2009) Nephrol Nurs J , vol.36 , pp. 389-392
    • Wick, G.1
  • 62
    • 84872791896 scopus 로고    scopus 로고
    • Use of intravenous iron supplementation in chronic kidney disease: An update
    • Macdougall IC, Geisser P: Use of intravenous iron supplementation in chronic kidney disease: an update. Iran J Kidney Dis 2013; 7: 9-22.
    • (2013) Iran J Kidney Dis , vol.7 , pp. 9-22
    • Macdougall, I.C.1    Geisser, P.2
  • 63
    • 84969776989 scopus 로고    scopus 로고
    • Very low doses of direct intravenous iron in each session as maintenance therapy in hemodialysis patients
    • Deira J, Gonzalez-Sanchidrian S, Polanco S, et al: Very low doses of direct intravenous iron in each session as maintenance therapy in hemodialysis patients. Ren Fail 2016; 38: 1076-1081.
    • (2016) Ren Fail , vol.38 , pp. 1076-1081
    • Deira, J.1    Gonzalez-Sanchidrian, S.2    Polanco, S.3
  • 64
    • 84959328814 scopus 로고    scopus 로고
    • Liver and cardiac iron deposition in patients on maintenance hemodialysis by magnetic resonance imaging T2
    • Tolouian R, Mulla ZD, Diaz J, Aguila J, Ramos-Duran L: Liver and cardiac iron deposition in patients on maintenance hemodialysis by magnetic resonance imaging T2. Iran J Kidney Dis 2016; 10: 68-74.
    • (2016) Iran J Kidney Dis , vol.10 , pp. 68-74
    • Tolouian, R.1    Mulla, Z.D.2    Diaz, J.3    Aguila, J.4    Ramos-Duran, L.5
  • 65
    • 85008887074 scopus 로고    scopus 로고
    • Characterization of hepatic and cardiac iron deposition during standard treatment of anaemia in haemodialysis
    • Holman R, Olynyk JK, Kulkarni H, Ferrari P: Characterization of hepatic and cardiac iron deposition during standard treatment of anaemia in haemodialysis. Nephrology (Carlton) 2017; 22: 114-117.
    • (2017) Nephrology (Carlton) , vol.22 , pp. 114-117
    • Holman, R.1    Olynyk, J.K.2    Kulkarni, H.3    Ferrari, P.4
  • 66
    • 84862558474 scopus 로고    scopus 로고
    • Evidence for tissue iron overload in long-term hemodialysis patients and the impact of withdrawing parenteral iron
    • Ghoti H, Rachmilewitz EA, Simon-Lopez R, et al: Evidence for tissue iron overload in long-term hemodialysis patients and the impact of withdrawing parenteral iron. Eur J Haematol 2012; 89: 87-93.
    • (2012) Eur J Haematol , vol.89 , pp. 87-93
    • Ghoti, H.1    Rachmilewitz, E.A.2    Simon-Lopez, R.3
  • 67
    • 85021712676 scopus 로고    scopus 로고
    • HFE gene mutation is a risk factor for tissue iron accumulation in hemodialysis patients
    • Turkmen E, Yildirim T, Yilmaz R, et al: HFE gene mutation is a risk factor for tissue iron accumulation in hemodialysis patients. Hemodial Int 2017; 21: 359-366.
    • (2017) Hemodial Int , vol.21 , pp. 359-366
    • Turkmen, E.1    Yildirim, T.2    Yilmaz, R.3
  • 68
    • 85006781113 scopus 로고    scopus 로고
    • Estimation of body iron stores
    • in Anderson GM, McLaren GD (eds) New York, Springer
    • Woorwood, M: Estimation of body iron stores; in Anderson GM, McLaren GD (eds): Iron Physiology and Pathophysiology in Humans. New York, Springer, 2012, pp 499-528.
    • (2012) Iron Physiology and Pathophysiology in Humans , pp. 499-528
    • Woorwood, M.1
  • 69
    • 79251526560 scopus 로고    scopus 로고
    • Serum iron markers are inadequate for guiding iron repletion in chronic kidney disease
    • Ferrari P, Kulkarni H, Dheda S, et al: Serum iron markers are inadequate for guiding iron repletion in chronic kidney disease. Clin J Am Soc Nephrol 2011; 6: 77-83.
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 77-83
    • Ferrari, P.1    Kulkarni, H.2    Dheda, S.3
  • 70
    • 0346656654 scopus 로고    scopus 로고
    • Association between serum ferritin and measures of inflammation, nutrition and iron in haemodialysis patients
    • Kalantar-Zadeh K, Rodriguez RA, Humphreys MH: Association between serum ferritin and measures of inflammation, nutrition and iron in haemodialysis patients. Nephrol Dial Transplant 2004; 19: 141-149.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 141-149
    • Kalantar-Zadeh, K.1    Rodriguez, R.A.2    Humphreys, M.H.3
  • 71
    • 27144435800 scopus 로고    scopus 로고
    • Intravenous iron supplementation in the anaemia of renal and cardiac failure-a double-edged sword
    • Slotki I: Intravenous iron supplementation in the anaemia of renal and cardiac failure-a double-edged sword? Nephrol Dial Transplant 2005; 20(suppl 7):vii16-vii23.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. vii16-vii23
    • Slotki, I.1
  • 72
    • 0034088831 scopus 로고    scopus 로고
    • Optimization of epoetin therapy with intravenous iron therapy in hemodialysis patients
    • Besarab A, Amin N, Ahsan M, et al: Optimization of epoetin therapy with intravenous iron therapy in hemodialysis patients. J Am Soc Nephrol 2000; 11: 530-538.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 530-538
    • Besarab, A.1    Amin, N.2    Ahsan, M.3
  • 73
    • 2942631560 scopus 로고    scopus 로고
    • Elevated serum transferrin saturation and mortality
    • Mainous AG 3rd, Gill JM, Carek PJ: Elevated serum transferrin saturation and mortality. Ann Fam Med 2004; 2: 133-138.
    • (2004) Ann Fam Med , vol.2 , pp. 133-138
    • Mainous, A.G.1    Gill, J.M.2    Carek, P.J.3
  • 74
    • 84983211453 scopus 로고    scopus 로고
    • Clinical use of iron chelators
    • in Anderson GM, McLaren GD (eds): New York, Springer
    • Porter JB, Hershko C: Clinical use of iron chelators; in Anderson GM, McLaren GD (eds): Iron Physiology and Pathophysiology in Humans. New York, Springer, 2012, pp 591-627.
    • (2012) Iron Physiology and Pathophysiology in Humans , pp. 591-627
    • Porter, J.B.1    Hershko, C.2
  • 75
    • 84904758882 scopus 로고    scopus 로고
    • Use of magnetic resonance imaging to monitor iron overload
    • Wood JC: Use of magnetic resonance imaging to monitor iron overload. Hematol Oncol Clin North Am 2014; 28: 747-764.
    • (2014) Hematol Oncol Clin North Am , vol.28 , pp. 747-764
    • Wood, J.C.1
  • 76
    • 84857373097 scopus 로고    scopus 로고
    • Nontransferrin bound iron: A key role in iron overload and iron toxicity
    • Brissot P, Ropert M, Le Lan C, Loreal O: Nontransferrin bound iron: a key role in iron overload and iron toxicity. Biochim Biophys Acta 2012; 1820: 403-410.
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 403-410
    • Brissot, P.1    Ropert, M.2    Le Lan, C.3    Loreal, O.4
  • 77
    • 21144441802 scopus 로고    scopus 로고
    • Redox active plasma iron in C282Y/C282Y hemochromatosis
    • Le Lan C, Loreal O, Cohen T, et al: Redox active plasma iron in C282Y/C282Y hemochromatosis. Blood 2005; 105: 4527-4531.
    • (2005) Blood , vol.105 , pp. 4527-4531
    • Le Lan, C.1    Loreal, O.2    Cohen, T.3
  • 78
    • 0038122576 scopus 로고    scopus 로고
    • Labile iron in parenteral iron formulations and its potential for generating plasma nontransferrin-bound iron in dialysis patients
    • Esposito BP, Breuer W, Slotki I, Cabantchik ZI: Labile iron in parenteral iron formulations and its potential for generating plasma nontransferrin-bound iron in dialysis patients. Eur J Clin Invest 2002; 32(suppl 1):42-49.
    • (2002) Eur J Clin Invest , vol.32 , pp. 42-49
    • Esposito, B.P.1    Breuer, W.2    Slotki, I.3    Cabantchik, Z.I.4
  • 79
  • 80
    • 85044037487 scopus 로고    scopus 로고
    • EU Clinical Trials Register. (accessed February 11, 2017)
    • EU Clinical Trials Register. https://www. clini c a l t r i a l s r e g i s t e r. e u / c t r-s e a r c h / t r i-al/2013-002267-25/GB (accessed February 11, 2017).
  • 81
    • 84933183002 scopus 로고    scopus 로고
    • Anaemia in kidney disease: Harnessing hypoxia responses for therapy
    • Koury MJ, Haase VH: Anaemia in kidney disease: harnessing hypoxia responses for therapy. Nat Rev Nephrol 2015; 11: 394-410.
    • (2015) Nat Rev Nephrol , vol.11 , pp. 394-410
    • Koury, M.J.1    Haase, V.H.2
  • 82
    • 85021383519 scopus 로고    scopus 로고
    • Improving global outcomes (kdigo) ckd-mbd update work group: Kdigo 2017 clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (ckd-mbd)
    • Kidney Disease
    • Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Update Work Group: KDIGO 2017 clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD). Kidney Int Suppl 2017; 7: 1-59.
    • (2017) Kidney Int Suppl , vol.7 , pp. 1-59


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.