메뉴 건너뛰기




Volumn 137, Issue , 2018, Pages 83-92

Safety and efficacy of sodium-glucose cotransporter 2 (SGLT2) inhibitors in type 1 diabetes: A systematic review and meta-analysis

Author keywords

Meta analysis; Sodium glucose cotransporter 2 inhibitors; Systematic review; Type 1 diabetes

Indexed keywords

CANAGLIFLOZIN; DAPAGLIFLOZIN; EMPAGLIFLOZIN; HEMOGLOBIN A1C; INSULIN; LIRAGLUTIDE; PLACEBO; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SOTAGLIFLOZIN; ANTIDIABETIC AGENT; SLC5A2 PROTEIN, HUMAN; SODIUM GLUCOSE COTRANSPORTER 2;

EID: 85041621110     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2018.01.004     Document Type: Review
Times cited : (33)

References (54)
  • 1
    • 85041598075 scopus 로고    scopus 로고
    • Type 1 diabetes facts. Juvenile diabetes research foundation. [accessed 5.5.17].
    • Type 1 diabetes facts. Juvenile diabetes research foundation. http://www.jdrf.org/about/fact-sheets/type-1-diabetes-facts/ [accessed 5.5.17].
  • 2
    • 85041580545 scopus 로고    scopus 로고
    • National Diabetes Statistics Report. Centers for diabetes control and prevention. [accessed 5.5.17].
    • National Diabetes Statistics Report. Centers for diabetes control and prevention. https://www.cdc.gov/diabetes/data/statistics/2014statisticsreport.html [accessed 5.5.17].
  • 3
    • 84869803914 scopus 로고    scopus 로고
    • Projections of type 1 and type 2 diabetes burden in the U.S. population aged <20 years through 2050
    • Impreatore, G., Boyle, J.P., Thompson, T.J., et al. Projections of type 1 and type 2 diabetes burden in the U.S. population aged <20 years through 2050. Diabetes Care 35:12 (2012), 2515–2520.
    • (2012) Diabetes Care , vol.35 , Issue.12 , pp. 2515-2520
    • Impreatore, G.1    Boyle, J.P.2    Thompson, T.J.3
  • 4
    • 85041629005 scopus 로고    scopus 로고
    • JDRF Impact. [accessed 5.5.17].
    • JDRF Impact. http://www2.jdrf.org/site/DocServer/2016_JDRF_Fact_Sheet.pdf?docID=5143 [accessed 5.5.17].
  • 5
    • 84899869077 scopus 로고    scopus 로고
    • Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009
    • Dabelea, D., Mayer-Davis, E.J., Saydah, S., et al. Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009. JAMA 311:17 (2014), 1778–1786.
    • (2014) JAMA , vol.311 , Issue.17 , pp. 1778-1786
    • Dabelea, D.1    Mayer-Davis, E.J.2    Saydah, S.3
  • 6
    • 84920509071 scopus 로고    scopus 로고
    • Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008–2010
    • Livingstone, S.J., Levin, D., Looker, H.C., et al. Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008–2010. JAMA 313:1 (2015), 37–44.
    • (2015) JAMA , vol.313 , Issue.1 , pp. 37-44
    • Livingstone, S.J.1    Levin, D.2    Looker, H.C.3
  • 7
    • 84964776844 scopus 로고    scopus 로고
    • (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group. Intensive diabetes treatment and cardiovascular outcomes in type 1 diabetes: the DCCT/EDIC study 30-year follow-up
    • The Diabetes Control and Complications Trial, (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group. Intensive diabetes treatment and cardiovascular outcomes in type 1 diabetes: the DCCT/EDIC study 30-year follow-up. Diabetes Care 39 (2016), 686–693.
    • (2016) Diabetes Care , vol.39 , pp. 686-693
    • The Diabetes Control and Complications Trial1
  • 8
    • 84942755473 scopus 로고    scopus 로고
    • Current state of type 1 diabetes treatment in the U.S.: updated data from the T1D exchange clinic registry
    • Miller, K.M., Foster, N.C., Beck, R.W., et al. Current state of type 1 diabetes treatment in the U.S.: updated data from the T1D exchange clinic registry. Diabetes Care 38:6 (2015), 971–978.
    • (2015) Diabetes Care , vol.38 , Issue.6 , pp. 971-978
    • Miller, K.M.1    Foster, N.C.2    Beck, R.W.3
  • 9
    • 84992142852 scopus 로고    scopus 로고
    • Approaches to glycemic treatment. Sec. 7. In standards of medical care in diabetes 2016
    • American Diabetes Association, Approaches to glycemic treatment. Sec. 7. In standards of medical care in diabetes 2016. Diabetes Care 39:1 (2016), S52–S59.
    • (2016) Diabetes Care , vol.39 , Issue.1 , pp. S52-S59
    • American Diabetes Association1
  • 10
    • 84959900934 scopus 로고    scopus 로고
    • Non-insulin drugs to treat hyperglycaemia in type 1 diabetes mellitus
    • Frandsen, C.S., Dejgaard, T.F., Madsbad, S., Non-insulin drugs to treat hyperglycaemia in type 1 diabetes mellitus. Lancet Diabetes Endocrinol 4:9 (2016), 766–780.
    • (2016) Lancet Diabetes Endocrinol , vol.4 , Issue.9 , pp. 766-780
    • Frandsen, C.S.1    Dejgaard, T.F.2    Madsbad, S.3
  • 11
    • 84872714268 scopus 로고    scopus 로고
    • Potential role of non-insulin adjunct therapy in type 1 diabetes
    • George, P., McCrimmon, R.J., Potential role of non-insulin adjunct therapy in type 1 diabetes. Diabetes Med 30:2 (2013), 179–188.
    • (2013) Diabetes Med , vol.30 , Issue.2 , pp. 179-188
    • George, P.1    McCrimmon, R.J.2
  • 12
    • 84922450117 scopus 로고    scopus 로고
    • Efficacy and safety of metformin for patients with type 1 diabetes mellitus: a meta-analysis
    • Liu, C., Wu, D., Zheng, X., et al. Efficacy and safety of metformin for patients with type 1 diabetes mellitus: a meta-analysis. Diabetes Technol Ther 17:2 (2015), 142–148.
    • (2015) Diabetes Technol Ther , vol.17 , Issue.2 , pp. 142-148
    • Liu, C.1    Wu, D.2    Zheng, X.3
  • 13
    • 84949522230 scopus 로고    scopus 로고
    • Effect of metformin added to insulin on glycemic control among overweight/obese adolescents with type 1 diabetes: a randomized clinical trial
    • Libman, I.M., Miller, K.M., DiMeglio, L.A., et al. Effect of metformin added to insulin on glycemic control among overweight/obese adolescents with type 1 diabetes: a randomized clinical trial. JAMA 314:21 (2015), 2241–2250.
    • (2015) JAMA , vol.314 , Issue.21 , pp. 2241-2250
    • Libman, I.M.1    Miller, K.M.2    DiMeglio, L.A.3
  • 14
    • 84889606485 scopus 로고    scopus 로고
    • Effect of pioglitazone on the course of new-onset type 1 diabetes mellitus
    • Tafuri, K.S., Godil, M.A., Lane, A.H., et al. Effect of pioglitazone on the course of new-onset type 1 diabetes mellitus. J Clin Res Pediatr Endocrinol 5:4 (2013), 236–239.
    • (2013) J Clin Res Pediatr Endocrinol , vol.5 , Issue.4 , pp. 236-239
    • Tafuri, K.S.1    Godil, M.A.2    Lane, A.H.3
  • 15
    • 84888860571 scopus 로고    scopus 로고
    • Liraglutide as additional treatment to insulin in obese patients with type 1 diabetes mellitus
    • Kuhadiya, N.D., Malik, R., Bellini, N.J., et al. Liraglutide as additional treatment to insulin in obese patients with type 1 diabetes mellitus. Endocrine Pract 19:6 (2013), 963–967.
    • (2013) Endocrine Pract , vol.19 , Issue.6 , pp. 963-967
    • Kuhadiya, N.D.1    Malik, R.2    Bellini, N.J.3
  • 16
    • 84878622622 scopus 로고    scopus 로고
    • Effect of sitagliptin on post-prandial glucagon and GLP-1 levels in patients with type 1 diabetes: investigator-initiated, double-blind, randomized, placebo-controlled trial
    • Garg, S.K., Moser, E.G., Bode, B.W., et al. Effect of sitagliptin on post-prandial glucagon and GLP-1 levels in patients with type 1 diabetes: investigator-initiated, double-blind, randomized, placebo-controlled trial. Endocrine Pract 19:1 (2013), 19–28.
    • (2013) Endocrine Pract , vol.19 , Issue.1 , pp. 19-28
    • Garg, S.K.1    Moser, E.G.2    Bode, B.W.3
  • 17
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • Rahmoune, H., Thompson, P.W., Ward, J.M., et al. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes 54 (2005), 3427–3434.
    • (2005) Diabetes , vol.54 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3
  • 18
    • 84864283226 scopus 로고    scopus 로고
    • SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects
    • Ferrannini, E., Solini, A., SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects. Nat Rev Endocrinol 8 (2012), 495–502.
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 495-502
    • Ferrannini, E.1    Solini, A.2
  • 19
    • 84858020943 scopus 로고    scopus 로고
    • Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
    • Bolinder, J., Ljunggren, O., Kullberg, J., et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metabol 997 (2012), 1020–1031.
    • (2012) J Clin Endocrinol Metabol , vol.997 , pp. 1020-1031
    • Bolinder, J.1    Ljunggren, O.2    Kullberg, J.3
  • 20
    • 84983452534 scopus 로고    scopus 로고
    • Sodium glucose cotransporter 2 (SGLT2) inhibitors: current status and future perspective
    • Madaan, T., Akhtar, M., Najmi, A.K., Sodium glucose cotransporter 2 (SGLT2) inhibitors: current status and future perspective. Eur J Pharm Sci 93 (2016), 244–252.
    • (2016) Eur J Pharm Sci , vol.93 , pp. 244-252
    • Madaan, T.1    Akhtar, M.2    Najmi, A.K.3
  • 21
    • 84903552407 scopus 로고    scopus 로고
    • Type 1 diabetes through the life span: a position statement of the American Diabetes Association
    • Chiang, J.L., Kirkman, M.S., Laffel, L.M., et al. Type 1 diabetes through the life span: a position statement of the American Diabetes Association. Diabetes Care 37 (2014), 2034–2054.
    • (2014) Diabetes Care , vol.37 , pp. 2034-2054
    • Chiang, J.L.1    Kirkman, M.S.2    Laffel, L.M.3
  • 22
    • 84969915634 scopus 로고    scopus 로고
    • Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis
    • Zaccardi, F., Webb, D.R., Htike, Z.Z., et al. Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis. Diabetes Obes Metab 18:8 (2016), 783–794.
    • (2016) Diabetes Obes Metab , vol.18 , Issue.8 , pp. 783-794
    • Zaccardi, F.1    Webb, D.R.2    Htike, Z.Z.3
  • 23
    • 84960439287 scopus 로고    scopus 로고
    • Comparative effectiveness of sodium-glucose co-transporter 2 inhibitors for controlling hyperglycaemia in patients with type 2 diabetes: protocol for a systematic review and network meta-analysis
    • Chen, M., Xie, C.-G., Gao, H., et al. Comparative effectiveness of sodium-glucose co-transporter 2 inhibitors for controlling hyperglycaemia in patients with type 2 diabetes: protocol for a systematic review and network meta-analysis. BMJ Open, 6(1), 2016, e010252.
    • (2016) BMJ Open , vol.6 , Issue.1 , pp. e010252
    • Chen, M.1    Xie, C.-G.2    Gao, H.3
  • 24
    • 84929676338 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin in subjects with type 2 diabetes: systematic review and meta-analysis
    • Yang, X.P., Lai, D., Zhong, X.Y., et al. Efficacy and safety of canagliflozin in subjects with type 2 diabetes: systematic review and meta-analysis. Eur J Clin Pharmacol 70:10 (2014), 1149–1158.
    • (2014) Eur J Clin Pharmacol , vol.70 , Issue.10 , pp. 1149-1158
    • Yang, X.P.1    Lai, D.2    Zhong, X.Y.3
  • 25
    • 84898854471 scopus 로고    scopus 로고
    • Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis
    • Baker, W.L., Smyth, L.R., Riche, D.M., et al. Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis. J Am Soc Hypertension 8:4 (2014), 262–275.
    • (2014) J Am Soc Hypertension , vol.8 , Issue.4 , pp. 262-275
    • Baker, W.L.1    Smyth, L.R.2    Riche, D.M.3
  • 26
    • 84898791935 scopus 로고    scopus 로고
    • Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials
    • Monami, M., Nardini, C., Mannucci, E., Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Diabetes Obes Metab 16:5 (2014), 457–466.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.5 , pp. 457-466
    • Monami, M.1    Nardini, C.2    Mannucci, E.3
  • 27
    • 84912533839 scopus 로고    scopus 로고
    • Efficacy and safety of empagliflozin for type 2 diabetes: a systematic review and meta-analysis
    • Liakos, A., Karagiannis, T., Athanasiadou, E., et al. Efficacy and safety of empagliflozin for type 2 diabetes: a systematic review and meta-analysis. Diabetes Obes Metab 16 (2014), 984–993.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 984-993
    • Liakos, A.1    Karagiannis, T.2    Athanasiadou, E.3
  • 28
    • 84911942671 scopus 로고    scopus 로고
    • The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozocin diabetes rat model by interfering with oxidative stress and glucotoxicity
    • Oelze, M., Kroller-Schon, S., Welschof, P., et al. The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozocin diabetes rat model by interfering with oxidative stress and glucotoxicity. PLoS ONE, 9(11), 2014, e112394.
    • (2014) PLoS ONE , vol.9 , Issue.11 , pp. e112394
    • Oelze, M.1    Kroller-Schon, S.2    Welschof, P.3
  • 29
    • 84971663895 scopus 로고    scopus 로고
    • The effects of empagliflozin, an SGLT2 inhibitor, on pancreatic β-cell mass and glucose homeostasis in type 1 diabetes
    • Cheng, S.T., Chen, L., Li, S.Y., et al. The effects of empagliflozin, an SGLT2 inhibitor, on pancreatic β-cell mass and glucose homeostasis in type 1 diabetes. PLoS ONE, 11(1), 2016, e0147391.
    • (2016) PLoS ONE , vol.11 , Issue.1 , pp. e0147391
    • Cheng, S.T.1    Chen, L.2    Li, S.Y.3
  • 30
    • 85019870969 scopus 로고    scopus 로고
    • Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose-induced oxidative stress in type 1 diabetic mice
    • Hatanaka, T., Ogawa, D., Tachibana, H., et al. Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose-induced oxidative stress in type 1 diabetic mice. Pharmacol Res Perspect, 4(4), 2016, e00239.
    • (2016) Pharmacol Res Perspect , vol.4 , Issue.4 , pp. e00239
    • Hatanaka, T.1    Ogawa, D.2    Tachibana, H.3
  • 31
    • 84962362243 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to insulin in patients with type 1 diabetes
    • Henry, R.R., Thakkar, P., Tong, C., et al. Efficacy and safety of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to insulin in patients with type 1 diabetes. Diabetes Care 38 (2015), 2258–2265.
    • (2015) Diabetes Care , vol.38 , pp. 2258-2265
    • Henry, R.R.1    Thakkar, P.2    Tong, C.3
  • 32
    • 84988912446 scopus 로고    scopus 로고
    • Dapagliflozin as additional treatment to liraglutide and insulin in patients with type 1 diabetes
    • Kuhadiya, N.D., Ghanim, H., Mehta, A., et al. Dapagliflozin as additional treatment to liraglutide and insulin in patients with type 1 diabetes. J Clin Endocrinol Metab 101:9 (2016), 3506–3515.
    • (2016) J Clin Endocrinol Metab , vol.101 , Issue.9 , pp. 3506-3515
    • Kuhadiya, N.D.1    Ghanim, H.2    Mehta, A.3
  • 33
    • 84939621365 scopus 로고    scopus 로고
    • Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes
    • Sands, A.T., Zambrowicz, B.P., Rosenstock, J., et al. Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, as adjunct therapy to insulin in type 1 diabetes. Diabetes Care 38 (2015), 1181–1188.
    • (2015) Diabetes Care , vol.38 , pp. 1181-1188
    • Sands, A.T.1    Zambrowicz, B.P.2    Rosenstock, J.3
  • 34
    • 84942258219 scopus 로고    scopus 로고
    • Empagliflozin as adjunct to insulin in patients with type 1 diabetes: a 4-week, randomized, placebo-controlled trial (EASE-1)
    • Pieber, T.R., Famulla, S., Eilbracht, et al. Empagliflozin as adjunct to insulin in patients with type 1 diabetes: a 4-week, randomized, placebo-controlled trial (EASE-1). Diabetes Obes Metab 17 (2015), 928–935.
    • (2015) Diabetes Obes Metab , vol.17 , pp. 928-935
    • Pieber, T.R.1    Famulla, S.2    Eilbracht3
  • 35
    • 84982890345 scopus 로고    scopus 로고
    • Glycemic effects of SGLT-2 inhibitor canagliflozin in type 1 diabetes patients using the Dexcom G4 platinum CGM
    • Argento, N.B., Nakamura, K., Glycemic effects of SGLT-2 inhibitor canagliflozin in type 1 diabetes patients using the Dexcom G4 platinum CGM. Endocrine Pract 22:3 (2016), 315–322.
    • (2016) Endocrine Pract , vol.22 , Issue.3 , pp. 315-322
    • Argento, N.B.1    Nakamura, K.2
  • 36
    • 84899105421 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter 2 inhibition and glycemic control in type 1 diabetes: results of an 8-week open-label proof-of-concept trial
    • Perkins, B.A., Cherney, D.Z., Partridge, H., et al. Sodium-glucose cotransporter 2 inhibition and glycemic control in type 1 diabetes: results of an 8-week open-label proof-of-concept trial. Diabetes Care 37:5 (2014), 1480–1483.
    • (2014) Diabetes Care , vol.37 , Issue.5 , pp. 1480-1483
    • Perkins, B.A.1    Cherney, D.Z.2    Partridge, H.3
  • 37
    • 84943329171 scopus 로고    scopus 로고
    • Dapagliflozin as adjunct therapy to insulin in the treatment of patients with type 1 diabetes mellitus
    • Tamez, H.E., Tamez, A.L., Garza, L.A., et al. Dapagliflozin as adjunct therapy to insulin in the treatment of patients with type 1 diabetes mellitus. J Diabetes Metabol Disord, 14, 2015, 78.
    • (2015) J Diabetes Metabol Disord , vol.14 , pp. 78
    • Tamez, H.E.1    Tamez, A.L.2    Garza, L.A.3
  • 38
    • 84892959743 scopus 로고    scopus 로고
    • The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus
    • Cherney, D.Z., Perkins, B.A., Soleymanlou, N., et al. The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus. Cardiovasc Diabetol, 13, 2014, 28.
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 28
    • Cherney, D.Z.1    Perkins, B.A.2    Soleymanlou, N.3
  • 39
    • 84893214045 scopus 로고    scopus 로고
    • Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus
    • Cherney, D.Z., Perkins, B.A., Soleymanlou, N., et al. Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation 129:5 (2014), 587–597.
    • (2014) Circulation , vol.129 , Issue.5 , pp. 587-597
    • Cherney, D.Z.1    Perkins, B.A.2    Soleymanlou, N.3
  • 40
    • 84952682963 scopus 로고    scopus 로고
    • Diurnal glycemic patterns during an 8-week open-label proof-of-concept trial of empagliflozin in type 1 diabetes
    • Perkins, B.A., Cherney, D.Z., Soleymanlou, N., et al. Diurnal glycemic patterns during an 8-week open-label proof-of-concept trial of empagliflozin in type 1 diabetes. PLoS ONE, 10(11), 2015, e0141085.
    • (2015) PLoS ONE , vol.10 , Issue.11 , pp. e0141085
    • Perkins, B.A.1    Cherney, D.Z.2    Soleymanlou, N.3
  • 41
    • 85011650209 scopus 로고    scopus 로고
    • The effect of canagliflozin, a sodium glucose cotransporter 2 inhibitor, on glycemic end points assessed by continuous glucose monitoring and patient-reported outcomes among people with type 1 diabetes
    • Rodbard, H.W., Peters, A.L., Slee, A., et al. The effect of canagliflozin, a sodium glucose cotransporter 2 inhibitor, on glycemic end points assessed by continuous glucose monitoring and patient-reported outcomes among people with type 1 diabetes. Diabetes Care 40:2 (2017), 171–180.
    • (2017) Diabetes Care , vol.40 , Issue.2 , pp. 171-180
    • Rodbard, H.W.1    Peters, A.L.2    Slee, A.3
  • 42
    • 85041583242 scopus 로고    scopus 로고
    • Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011]. The Cochrane Collaboration. Available from
    • Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from http://handbook.cochrane.org.
    • (2011)
    • Higgins, J.P.T.1    Green, S.2
  • 44
    • 68049122102 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • Moher, D., Liberati, A., Tetzlaff, J., et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med, 6(7), 2009, e1000097.
    • (2009) PLoS Med , vol.6 , Issue.7 , pp. e1000097
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 45
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group, The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329 (1993), 977–986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
    • The Diabetes Control and Complications Trial Research Group1
  • 46
    • 84903552407 scopus 로고    scopus 로고
    • Type 1 diabetes through the life span: a position statement of the American Diabetes Association
    • Chiang, J.L., Kirkman, M.S., Laffel, L.M.B., et al. Type 1 diabetes through the life span: a position statement of the American Diabetes Association. Diabetes Care 37 (2014), 2034–2054.
    • (2014) Diabetes Care , vol.37 , pp. 2034-2054
    • Chiang, J.L.1    Kirkman, M.S.2    Laffel, L.M.B.3
  • 47
    • 84959890006 scopus 로고    scopus 로고
    • Characterization and comparison of sodium-glucose cotransporter 2 inhibitors in pharmacokinetics, pharmacodynamics, and pharmacologic effects
    • Tahara, A., Takasu, T., Yokono, M., et al. Characterization and comparison of sodium-glucose cotransporter 2 inhibitors in pharmacokinetics, pharmacodynamics, and pharmacologic effects. J Pharmacol Sci 130:3 (2016), 159–169.
    • (2016) J Pharmacol Sci , vol.130 , Issue.3 , pp. 159-169
    • Tahara, A.1    Takasu, T.2    Yokono, M.3
  • 48
    • 0035998739 scopus 로고    scopus 로고
    • Unresolved challenges with insulin therapy in type 1 and type 2 diabetes: potential benefit of replacing amylin, a second β-cell hormone
    • Edelman, S.V., Weyer, C., Unresolved challenges with insulin therapy in type 1 and type 2 diabetes: potential benefit of replacing amylin, a second β-cell hormone. Diabetes Technol Ther 4:2 (2004), 175–189.
    • (2004) Diabetes Technol Ther , vol.4 , Issue.2 , pp. 175-189
    • Edelman, S.V.1    Weyer, C.2
  • 49
    • 84939142605 scopus 로고    scopus 로고
    • SGLT2 inhibitors may predispose to ketoacidosis
    • Taylor, S.I., Blau, J.E., Rother, K.I., SGLT2 inhibitors may predispose to ketoacidosis. J Clin Endocrinol Metab 100:8 (2015), 2849–2852.
    • (2015) J Clin Endocrinol Metab , vol.100 , Issue.8 , pp. 2849-2852
    • Taylor, S.I.1    Blau, J.E.2    Rother, K.I.3
  • 50
    • 85021627131 scopus 로고    scopus 로고
    • Biopsychosocial aspects of weight management in type 1 diabetes: a review and next steps
    • Driscoll, K.A., Corbin, K.D., Maahs, D.M., et al. Biopsychosocial aspects of weight management in type 1 diabetes: a review and next steps. Curr DiabRep, 17(8), 2017, 58.
    • (2017) Curr DiabRep , vol.17 , Issue.8 , pp. 58
    • Driscoll, K.A.1    Corbin, K.D.2    Maahs, D.M.3
  • 51
    • 85041611202 scopus 로고    scopus 로고
    • FDA drug safety communication: FDA warns that SGLT2 inhibitors for diabetes may result in a serious condition of too much acid in the blood. Available from: [accessed 11.21.17].
    • Food and Drug Administration. FDA drug safety communication: FDA warns that SGLT2 inhibitors for diabetes may result in a serious condition of too much acid in the blood. Available from: https://www.fda.gov/safety/medwatch/safetyinformation/safetyalertsforhumanmedicalproducts/ucm475553.htm [accessed 11.21.17].
    • Food and Drug Administration1
  • 52
    • 85019751779 scopus 로고    scopus 로고
    • Effects of SGLT-2 inhibitors on diabetic ketoacidosis: a meta-analysis of randomised controlled trials
    • Monami, M., Nreu, B., Zannoni, S., et al. Effects of SGLT-2 inhibitors on diabetic ketoacidosis: a meta-analysis of randomised controlled trials. Diabetes Res Clin Pract 130 (2017), 53–60.
    • (2017) Diabetes Res Clin Pract , vol.130 , pp. 53-60
    • Monami, M.1    Nreu, B.2    Zannoni, S.3
  • 53
    • 85014928963 scopus 로고    scopus 로고
    • The efficacy and safety of SGLT2 inhibitors for adjunctive treatment of type 1 diabetes: a systematic review and meta-analysis
    • Chen, J., Fan, F., Wang, J., et al. The efficacy and safety of SGLT2 inhibitors for adjunctive treatment of type 1 diabetes: a systematic review and meta-analysis. Sci Rep, 7, 2017, 44128.
    • (2017) Sci Rep , vol.7 , pp. 44128
    • Chen, J.1    Fan, F.2    Wang, J.3
  • 54
    • 85021810641 scopus 로고    scopus 로고
    • Efficacy and safety of SGLT2 inhibitors in patients with type 1 diabetes: a meta-analysis of randomized controlled trials
    • Yang, Y., Pan, H., Wang, B., et al. Efficacy and safety of SGLT2 inhibitors in patients with type 1 diabetes: a meta-analysis of randomized controlled trials. Chin Med Sci J 32:1 (2017), 22–27.
    • (2017) Chin Med Sci J , vol.32 , Issue.1 , pp. 22-27
    • Yang, Y.1    Pan, H.2    Wang, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.