ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer

Oncotarget

Volumn 9, Issue 10, 2018, Pages 8823-8835

  Pilling, Amanda B ^a,b   Kim, Jihye ^a   Estrada Bernal, Adriana ^a   Zhou, Qiong ^a   Le, Anh T ^a   Singleton, Katherine R ^a   Heasley, Lynn E ^a   Tan, Aik Choon ^a   DeGregori, James ^a   Doebele, Robert C ^a  

^a UNIVERSITY OF COLORADO CANCER CENTER   (United States)

^b Henry Ford Transplant Institute   (United States)

Author keywords

ALK; MYC; NSCLC; ROS1; Synthetic lethality

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; CRIZOTINIB; MESSENGER RNA; MYC PROTEIN; SHORT HAIRPIN RNA;

ALK GENE; ARTICLE; CANCER RESISTANCE; CANCER SURVIVAL; CELL DEATH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; GENE EXPRESSION; GENE REARRANGEMENT; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; MYCBP GENE; NCI-H2228 CELL LINE; NCI-H3122 CELL LINE; NON SMALL CELL LUNG CANCER; ONCOGENE; ONCOGENE C MYC; PROTEIN FUNCTION; PROTEIN STABILITY; RNA SEQUENCE; SLIC GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 85041399074     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.24260     Document Type: Article

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