Resolving systematic errors in widely used enhancer activity assays in human cells

Nature Methods

Volumn 15, Issue 2, 2018, Pages 141-149

  Muerdter, Felix ^a   Boryn, Łukasz M ^a   Woodfin, Ashley R ^a   Neumayr, Christoph ^a   Rath, Martina ^a   Zabidi, Muhammad A ^a   Pagani, Michaela ^a   Haberle, Vanja ^a   Kazmar, Tomáš ^a   Catarino, Rui R ^a   Schernhuber, Katharina ^a   Arnold, Cosmas D ^a   Stark, Alexander ^a,b  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; DOUBLE STRANDED RNA; EXTRACHROMOSOMAL DNA; I KAPPA B KINASE; INTERFERON; INTERFERON REGULATORY FACTOR 3; MAX PROTEIN; MESSENGER RNA; MYC PROTEIN; PROTEIN C JUN; PROTEIN KINASE R; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN;

ARTICLE; CELL ASSAY; CHROMATIN; COMPARATIVE STUDY; CONTROLLED STUDY; DNA REPLICATION ORIGIN; DNA TRANSFECTION; ENHANCER REGION; EPISOME; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; GENE EXPRESSION; GENE ONTOLOGY; GENETIC TRANSFECTION; HCT 116 CELL LINE; HELA S3 CELL LINE; HUMAN; HUMAN CELL; HUMAN GENOME; LUCIFERASE ASSAY; NEXT GENERATION SEQUENCING; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; SYSTEMATIC ERROR; CHROMOSOMAL MAPPING; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; REPORTER GENE;

CHROMATIN; CHROMOSOME MAPPING; ENHANCER ELEMENTS, GENETIC; FALSE NEGATIVE REACTIONS; GENE EXPRESSION REGULATION; GENES, REPORTER; GENOME, HUMAN; HELA CELLS; HUMANS; PROMOTER REGIONS, GENETIC;

EID: 85041354653     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.4534     Document Type: Article

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