Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility

Proceedings of the National Academy of Sciences of the United States of America

Volumn 115, Issue 5, 2018, Pages 1111-1116

  Heshmati, Mitra ^a   Aleyasin, Hossein ^a   Menard, Caroline ^a   Christoffel, Daniel J ^b   Flanigan, Meghan E ^a   Pfau, Madeline L ^a   Hodes, Georgia E ^a,g   Lepack, Ashley E ^a   Bicks, Lucy K ^a   Takahashi, Aki ^a,c   Chandra, Ramesh ^d   Turecki, Gustavo ^e   Lobo, Mary Kay ^d   Maze, Ian ^a   Golden, Sam A ^f   Russo, Scott J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e MCGILL UNIVERSITY   (Canada)

^f NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^g VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Depression; Dominance; Medium spiny neuron; Neuroligin 2; Social defeat stress

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; ANTIDEPRESSANT AGENT; MESSENGER RNA; MICRORNA; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; NEUROLIGIN 2;

ADULT; AGGRESSION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SPECIFICITY; CHRONIC STRESS; CONTROLLED STUDY; COPING BEHAVIOR; DEFENSIVE BEHAVIOR; DOMINANCE BEHAVIOR; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE KNOCKDOWN; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR DEPRESSION; MALE; MOUSE; NLGN 2 GENE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CELL LINE; DISEASE MODEL; DOMINANT-SUBORDINATE RELATIONSHIP; HETEROZYGOTE; MENTAL STRESS; METABOLISM; PATHOPHYSIOLOGY; SOCIAL BEHAVIOR; SYNAPSE; TRANSGENIC MOUSE;

AGGRESSION; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; CELL ADHESION MOLECULES, NEURONAL; CELL LINE; DEPRESSIVE DISORDER, MAJOR; DISEASE MODELS, ANIMAL; DOMINANCE-SUBORDINATION; HETEROZYGOTE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRORNAS; NERVE TISSUE PROTEINS; NUCLEUS ACCUMBENS; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RNA, MESSENGER; SOCIAL BEHAVIOR; STRESS, PSYCHOLOGICAL; SYNAPSES;

EID: 85041235765     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1719014115     Document Type: Article

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