Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens

Biological Psychiatry

Volumn 79, Issue 11, 2016, Pages 898-905

  Khibnik, Lena A ^a   Beaumont, Michael ^a   Doyle, Marie ^a   Heshmati, Mitra ^a   Slesinger, Paul A ^a   Nestler, Eric J ^a   Russo, Scott J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic social defeat stress; Cocaine addiction; Dendritic spine; Glutamate uncaging; Nucleus accumbens; Synaptic transmission

Indexed keywords

COCAINE; DOPAMINE 1 RECEPTOR; GLUTAMIC ACID; DOPAMINE 2 RECEPTOR; DOPAMINE UPTAKE INHIBITOR; DRD1A PROTEIN, MOUSE; DRD2 PROTEIN, MOUSE; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL DENSITY; CHRONIC STRESS; CONTROLLED STUDY; DENDRITIC SPINE; DOWN REGULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; LASER MICROSCOPY; LOCOMOTION; LONG TERM EXPOSURE; MALE; MEMBRANE CURRENT; MOUSE; MUSHROOM SPINE; NONHUMAN; NUCLEUS ACCUMBENS SHELL; PLACE PREFERENCE; PRIORITY JOURNAL; SOCIAL STRESS; SYNAPTIC STRENGTH; SYNAPTIC TRANSMISSION; UPREGULATION; VENTRAL TEGMENTUM; WHOLE CELL PATCH CLAMP; ANIMAL; C57BL MOUSE; CONFOCAL MICROSCOPY; DRUG EFFECTS; GENETICS; MENTAL STRESS; METABOLISM; NUCLEUS ACCUMBENS; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; PHYSIOLOGY; SOCIAL DOMINANCE; TISSUE CULTURE TECHNIQUE; TRANSGENIC MOUSE; WITHDRAWAL SYNDROME;

ANIMALS; COCAINE; DENDRITIC SPINES; DOMINANCE-SUBORDINATION; DOPAMINE UPTAKE INHIBITORS; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUTAMIC ACID; GREEN FLUORESCENT PROTEINS; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; NUCLEUS ACCUMBENS; PATCH-CLAMP TECHNIQUES; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; STRESS, PSYCHOLOGICAL; SUBSTANCE WITHDRAWAL SYNDROME; SYNAPTIC TRANSMISSION; TISSUE CULTURE TECHNIQUES;

EID: 84936818722     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2015.05.022     Document Type: Article

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