Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression

Nature Medicine

Volumn 19, Issue 3, 2013, Pages 337-344

  Golden, Sam A ^a   Christoffel, Daniel J ^a   Heshmati, Mitra ^a   Hodes, Georgia E ^a   Magida, Jane ^a   Davis, Keithara ^a   Cahill, Michael E ^a   Dias, Caroline ^a   Ribeiro, Efrain ^a   Ables, Jessica L ^b   Kennedy, Pamela J ^a   Robison, Alfred J ^a   Gonzalez Maeso, Javier ^a   Neve, Rachael L ^c   Turecki, Gustavo ^d   Ghose, Subroto ^e   Tamminga, Carol A ^e   Russo, Scott J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COFILIN; RAC1 PROTEIN;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC SOCIAL DEFEAT STRESS; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; ENZYME INHIBITION; EPIGENETICS; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SOCIAL AVOIDANCE BEHAVIOR; SOCIAL STRESS; SYNAPTOGENESIS;

ACTIN DEPOLYMERIZING FACTORS; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BEHAVIOR, ANIMAL; DENDRITIC SPINES; DEPRESSIVE DISORDER, MAJOR; EPIGENESIS, GENETIC; GENE EXPRESSION PROFILING; HISTONES; HUMANS; IMIPRAMINE; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NUCLEUS ACCUMBENS; PROMOTER REGIONS, GENETIC; RAC1 GTP-BINDING PROTEIN; SOCIAL BEHAVIOR; STRESS DISORDERS, TRAUMATIC; STRESS, PSYCHOLOGICAL; TRANSCRIPTION, GENETIC;

MUS; RODENTIA;

EID: 84875164187     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3090     Document Type: Article

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