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Volumn 6, Issue 12, 2017, Pages 1-5

A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay

Author keywords

Cellular morphology; High content screening; Image based screening; Phenotypic profiling; Small molecule library; U2OS

Indexed keywords

CELL ASSAY; CELL PAINTING ASSAY; CELL STRUCTURE; COMPUTATIONAL FLUID DYNAMICS; IMAGE ANALYSIS; INFORMATION PROCESSING; MICROSCOPY; NOTE; PHENOTYPE; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; CELL LINE; CELLS; DRUG EFFECT; HUMAN; IMAGE PROCESSING; MOLECULAR LIBRARY; ULTRASTRUCTURE;

EID: 85040750802     PISSN: None     EISSN: 2047217X     Source Type: Journal    
DOI: 10.1093/gigascience/giw014     Document Type: Note
Times cited : (127)

References (27)
  • 1
    • 77149130553 scopus 로고    scopus 로고
    • Automated microscopy for highcontent RNAi screening
    • Conrad C, Gerlich DW. Automated microscopy for highcontent RNAi screening. J Cell Biol 2010;188(4):453-61
    • (2010) J Cell Biol , vol.188 , Issue.4 , pp. 453-461
    • Conrad, C.1    Gerlich, D.W.2
  • 2
    • 77949408218 scopus 로고    scopus 로고
    • High-content screening: a decade of evolution
    • Thomas N. High-content screening: a decade of evolution. J Biomol Screen 2010;15(1):1-9
    • (2010) J Biomol Screen , vol.15 , Issue.1 , pp. 1-9
    • Thomas, N.1
  • 3
    • 77955985403 scopus 로고    scopus 로고
    • The beautiful cell: high-content screening in drug discovery
    • Bickle M. The beautiful cell: high-content screening in drug discovery. Anal Bioanal Chem 2010;398(1):219-26
    • (2010) Anal Bioanal Chem , vol.398 , Issue.1 , pp. 219-226
    • Bickle, M.1
  • 4
    • 84949495449 scopus 로고    scopus 로고
    • Microscopy-based highcontent screening
    • Boutros M, Heigwer F, Laufer C. Microscopy-based highcontent screening. Cell 2015;163(6):1314-25
    • (2015) Cell , vol.163 , Issue.6 , pp. 1314-1325
    • Boutros, M.1    Heigwer, F.2    Laufer, C.3
  • 5
    • 0037213715 scopus 로고    scopus 로고
    • Gene expression and the myth of the average cell
    • Levsky JM, Singer RH. Gene expression and the myth of the average cell. Trends Cell Biol 2003;13(1):4-6
    • (2003) Trends Cell Biol , vol.13 , Issue.1 , pp. 4-6
    • Levsky, J.M.1    Singer, R.H.2
  • 6
    • 78951470515 scopus 로고    scopus 로고
    • Origins of regulated cell-to-cell variability
    • Snijder B, Pelkmans L. Origins of regulated cell-to-cell variability. Nat Rev Mol Cell Biol 2011;12(2):119-25
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.2 , pp. 119-125
    • Snijder, B.1    Pelkmans, L.2
  • 7
    • 77952474987 scopus 로고    scopus 로고
    • Cellular heterogeneity: do differences make a difference?
    • Altschuler SJ, Wu LF. Cellular heterogeneity: do differences make a difference? Cell 2010 14;141(4):559-63
    • (2010) Cell , vol.141 , Issue.4 , pp. 559-563
    • Altschuler, S.J.1    Wu, L.F.2
  • 8
    • 84905046441 scopus 로고    scopus 로고
    • Toward performancediverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling
    • Wawer MJ, Li K, Gustafsdottir SM et al. Toward performancediverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling. Proc Natl Acad Sci U S A 2014;111(30):10911-6
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.30 , pp. 10911-10916
    • Wawer, M.J.1    Li, K.2    Gustafsdottir, S.M.3
  • 9
    • 85015335626 scopus 로고    scopus 로고
    • Cell Painting, a highcontent image-based assay for morphological profiling usingmultiplexed fluorescent dyes
    • Bray M, Singh S, Han H et al. Cell Painting, a highcontent image-based assay for morphological profiling usingmultiplexed fluorescent dyes. Nat Protoc 2016;11(9):1757-74
    • (2016) Nat Protoc , vol.11 , Issue.9 , pp. 1757-1774
    • Bray, M.1    Singh, S.2    Han, H.3
  • 10
    • 8444225024 scopus 로고    scopus 로고
    • Molecular biology: NIH molecular libraries initiative
    • Austin CP, Brady LS, Insel TR et al. Molecular biology: NIH molecular libraries initiative. Science 2004;306(5699): 1138-9
    • (2004) Science , vol.306 , Issue.5699 , pp. 1138-1139
    • Austin, C.P.1    Brady, L.S.2    Insel, T.R.3
  • 11
    • 85042385108 scopus 로고    scopus 로고
    • Human U2OS cells-compound cell-painting experiment
    • Accessed 2 October 2017
    • Gustafsdottir SM, Ljosa V, Sokolnicki KL et al. Human U2OS cells-compound cell-painting experiment. The Cell Image Library 2015. http://www.cellimagelibrary.org/pages/project 20269. Accessed 2 October 2017
    • (2015) The Cell Image Library
    • Gustafsdottir, S.M.1    Ljosa, V.2    Sokolnicki, K.L.3
  • 12
    • 85026475117 scopus 로고    scopus 로고
    • The image data resource: a bioimage data integration and publication platform
    • Williams E, Moore J, Li SW et al. The image data resource: a bioimage data integration and publication platform. Nat Methods 2017;14(8):775-81
    • (2017) Nat Methods , vol.14 , Issue.8 , pp. 775-781
    • Williams, E.1    Moore, J.2    Li, S.W.3
  • 13
    • 85042371610 scopus 로고    scopus 로고
    • Accessed 2 October 2017
    • IDR0016 from the Image Data Resource. http://idr. openmicroscopy.org/webclient/?show=screen-1251. Accessed 2 October 2017
    • IDR0016 from the Image Data Resource
  • 14
    • 79954500285 scopus 로고    scopus 로고
    • Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software
    • Kamentsky L, Jones TR, Fraser A et al. Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software. Bioinformatics 2011;27(8):1179-80
    • (2011) Bioinformatics , vol.27 , Issue.8 , pp. 1179-1180
    • Kamentsky, L.1    Jones, T.R.2    Fraser, A.3
  • 15
    • 84911493504 scopus 로고    scopus 로고
    • Pipeline for illumination correction of images for high-throughput microscopy
    • Singh S, Bray M-A, Jones TR et al. Pipeline for illumination correction of images for high-throughput microscopy. J Microsc 2014;256(3):231-6
    • (2014) J Microsc , vol.256 , Issue.3 , pp. 231-236
    • Singh, S.1    Bray, M.-A.2    Jones, T.R.3
  • 16
    • 84856292873 scopus 로고    scopus 로고
    • Workflow and metrics for image quality control in large-scale high-content screens
    • Bray M, Fraser AN, Hasaka TP et al. Workflow and metrics for image quality control in large-scale high-content screens. J Biomol Screen 2012;17(2):266-74
    • (2012) J Biomol Screen , vol.17 , Issue.2 , pp. 266-274
    • Bray, M.1    Fraser, A.N.2    Hasaka, T.P.3
  • 17
    • 85032644960 scopus 로고    scopus 로고
    • Quality control for high-throughput imaging experiments using machine learning in CellProfiler
    • Bray M-A, Carpenter AE. Quality control for high-throughput imaging experiments using machine learning in CellProfiler. Methods Mol Biol 2018;1683:89-112
    • (2018) Methods Mol Biol , vol.1683 , pp. 89-112
    • Bray, M.-A.1    Carpenter, A.E.2
  • 18
    • 85042352545 scopus 로고    scopus 로고
    • Supporting data for "A dataset of images andmorphological profiles of 30,000 small-molecule treatments using the Cell Painting assay."
    • Bray AM, Gustafsdottir SM, Singh S et al. Supporting data for "A dataset of images andmorphological profiles of 30,000 small-molecule treatments using the Cell Painting assay." GigaScience Database 2017. http://dx.doi.org/10.5524/100351
    • (2017) GigaScience Database
    • Bray, A.M.1    Gustafsdottir, S.M.2    Singh, S.3
  • 19
    • 85042376074 scopus 로고    scopus 로고
    • Source code from "A dataset of images and morphological profiles of 30,000 small-molecule treatments using the Cell Painting assay."
    • Source code from "A dataset of images and morphological profiles of 30,000 small-molecule treatments using the Cell Painting assay." GitHub 2017. https://github.com/gigascience/paper-bray2017. Accessed 2 October 2017
    • (2017) GitHub
  • 20
    • 85042379261 scopus 로고    scopus 로고
    • Supporting data files, documentation, and updated tips for "Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes."
    • Accessed 2 October 2017
    • Supporting data files, documentation, and updated tips for "Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes." GitHub 2017. https://github.com/carpenterlab/2016 bray natprot. Accessed 2 October 2017
    • (2017) GitHub
  • 21
    • 84887943419 scopus 로고    scopus 로고
    • Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment
    • Ljosa V, Caie PD, TerHorst R et al. Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment. J Biomol Screen 2013;18(10): 1321-9
    • (2013) J Biomol Screen , vol.18 , Issue.10 , pp. 1321-1329
    • Ljosa, V.1    Caie, P.D.2    Ter Horst, R.3
  • 22
    • 85042354968 scopus 로고    scopus 로고
    • Cytominer: methods for image-based cell profiling
    • Accessed 2 October 2017
    • Cytominer: methods for image-based cell profiling. GitHub 2017 https://github.com/cytomining/cytominer. Accessed 2 October 2017
    • (2017) GitHub
  • 23
    • 85028727120 scopus 로고    scopus 로고
    • Data-analysis strategies for image-based cell profiling
    • Caicedo JC, Cooper S, Heigwer F et al. Data-analysis strategies for image-based cell profiling. Nat Methods 2017;14(9):849-63
    • (2017) Nat Methods , vol.14 , Issue.9 , pp. 849-863
    • Caicedo, J.C.1    Cooper, S.2    Heigwer, F.3
  • 25
    • 84891388151 scopus 로고    scopus 로고
    • Multiplex cytological profiling assay to measure diverse cellular states
    • Gustafsdottir SM, Ljosa V, Sokolnicki KL et al. Multiplex cytological profiling assay to measure diverse cellular states. PLoS One 2013;8(12):e80999
    • (2013) PLoS One , vol.8 , Issue.12
    • Gustafsdottir, S.M.1    Ljosa, V.2    Sokolnicki, K.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.