Comprehensive computational design of ordered peptide macrocycles

Science

Volumn 358, Issue 6369, 2017, Pages 1461-1466

  Hosseinzadeh, Parisa ^a   Bhardwaj, Gaurav ^a   Mulligan, Vikram Khipple ^e   Shortridge, Matthew D ^b   Craven, Timothy W ^a   Pardo Avila, Fátima ^c   Rettie, Stephen A ^a   Kim, David E ^a   Silva, Daniel Adriano ^a   Ibrahim, Yehia M ^d   Webb, Ian K ^d   Cort, John R ^d   Adkins, Joshua N ^d   Varani, Gabriele ^b   Baker, David ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DEXTRO AMINO ACID; MACROCYCLIC COMPOUND; MACROCYCLIC PEPTIDE; PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID; DRUG; EXPERIMENTAL DESIGN; NUCLEAR MAGNETIC RESONANCE; PEPTIDE; PREDICTION; SAMPLING;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; ENERGY; MOLECULAR LIBRARY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; CHEMICAL MODEL; CHEMISTRY; COMPUTER AIDED DESIGN; COMPUTER SIMULATION; PROTEIN FOLDING; PROTEIN STABILITY;

COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; DRUG DESIGN; MODELS, CHEMICAL; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PROTEIN FOLDING; PROTEIN STABILITY;

EID: 85040187593     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aap7577     Document Type: Article

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