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Volumn 36, Issue 1, 2018, Pages 7-13

Dabrafenib and trametinib treatment in patients with locally advanced or metastatic BRAF V600–mutant anaplastic thyroid cancer

(14)  Subbiah, Vivek a   Cabanillas, Maria E a   Kreitman, Robert J b   Wainberg, Zev A c   Cho, Jae Yong d   Keam, Bhumsuk e   Schellens, Jan H M f,g   Soria, Jean Charles h   Wen, Patrick Y i   Zielinski, Christoph j   Urbanowitz, Gladys k   Mookerjee, Bijoyesh k   Wang, Dazhe k   Rangwala, Fatima k  


Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DABRAFENIB; TRAMETINIB; ANTINEOPLASTIC AGENT; BRAF PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; OXIME; PYRIDONE DERIVATIVE; PYRIMIDINONE DERIVATIVE;

EID: 85039975292     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2017.73.6785     Document Type: Article
Times cited : (649)

References (30)
  • 1
    • 0031028402 scopus 로고    scopus 로고
    • Prognostic factors for thyroid carcinoma. A population-based study of 15,698 cases from the Surveillance, Epidemiology and End Results (SEER) Program 1973-1991
    • Gilliland FD, Hunt WC, Morris DM, et al: Prognostic factors for thyroid carcinoma. A population-based study of 15,698 cases from the Surveillance, Epidemiology and End Results (SEER) Program 1973-1991. Cancer 79:564-573, 1997
    • (1997) Cancer , vol.79 , pp. 564-573
    • Gilliland, F.D.1    Hunt, W.C.2    Morris, D.M.3
  • 2
    • 15744362272 scopus 로고    scopus 로고
    • Anaplastic thyroid carcinoma. Treatment outcome and prognostic factors
    • Kebebew E, Greenspan FS, Clark OH, et al: Anaplastic thyroid carcinoma. Treatment outcome and prognostic factors. Cancer 103:1330-1335, 2005
    • (2005) Cancer , vol.103 , pp. 1330-1335
    • Kebebew, E.1    Greenspan, F.S.2    Clark, O.H.3
  • 3
    • 85018322461 scopus 로고    scopus 로고
    • Patterns of treatment failure in anaplastic thyroid carcinoma
    • Rao SN, Zafereo M, Dadu R, et al: Patterns of treatment failure in anaplastic thyroid carcinoma. Thyroid 27:672-681, 2017
    • (2017) Thyroid , vol.27 , pp. 672-681
    • Rao, S.N.1    Zafereo, M.2    Dadu, R.3
  • 5
    • 84986216553 scopus 로고    scopus 로고
    • Recurrence and survival after gross total removal of resectable undifferentiated or poorly differentiated thyroid carcinoma
    • Lee DY, Won JK, Choi HS, et al: Recurrence and survival after gross total removal of resectable undifferentiated or poorly differentiated thyroid carcinoma. Thyroid 26:1259-1268, 2016
    • (2016) Thyroid , vol.26 , pp. 1259-1268
    • Lee, D.Y.1    Won, J.K.2    Choi, H.S.3
  • 6
    • 84885348643 scopus 로고    scopus 로고
    • Genetic mutations in the treatment of anaplastic thyroid cancer: A systematic review
    • Guerra A, Di Crescenzo V, Garzi A, et al: Genetic mutations in the treatment of anaplastic thyroid cancer: A systematic review. BMC Surg 13:S44, 2013 (suppl 2)
    • (2013) BMC Surg , vol.13 , pp. S44
    • Guerra, A.1    Di Crescenzo, V.2    Garzi, A.3
  • 7
    • 84926511800 scopus 로고    scopus 로고
    • Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing
    • Kunstman JW, Juhlin CC, Goh G, et al: Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing. Hum Mol Genet 24:2318-2329, 2015
    • (2015) Hum Mol Genet , vol.24 , pp. 2318-2329
    • Kunstman, J.W.1    Juhlin, C.C.2    Goh, G.3
  • 8
    • 84959862166 scopus 로고    scopus 로고
    • Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
    • Landa I, Ibrahimpasic T, Boucai L, et al: Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers. J Clin Invest 126:1052-1066, 2016
    • (2016) J Clin Invest , vol.126 , pp. 1052-1066
    • Landa, I.1    Ibrahimpasic, T.2    Boucai, L.3
  • 9
    • 85009135117 scopus 로고    scopus 로고
    • Real-time genomic characterization utilizing circulating cell-free DNA in patients with anaplastic thyroid carcinoma
    • Sandulache VC, Williams MD, Lai SY, et al: Real-time genomic characterization utilizing circulating cell-free DNA in patients with anaplastic thyroid carcinoma. Thyroid 27:81-87, 2017
    • (2017) Thyroid , vol.27 , pp. 81-87
    • Sandulache, V.C.1    Williams, M.D.2    Lai, S.Y.3
  • 10
    • 0035666788 scopus 로고    scopus 로고
    • Anaplastic thyroid carcinoma: A 50-year experience at a single institution
    • McIver B, Hay ID, Giuffrida DF, et al: Anaplastic thyroid carcinoma: A 50-year experience at a single institution. Surgery 130:1028-1034, 2001
    • (2001) Surgery , vol.130 , pp. 1028-1034
    • McIver, B.1    Hay, I.D.2    Giuffrida, D.F.3
  • 11
    • 84898411721 scopus 로고    scopus 로고
    • P53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer
    • McFadden DG, Vernon A, Santiago PM, et al: p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer. Proc Natl Acad Sci USA 111:E1600-E1609, 2014
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E1600-E1609
    • McFadden, D.G.1    Vernon, A.2    Santiago, P.M.3
  • 12
    • 84868224906 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
    • Flaherty KT, Infante JR, Daud A, et al: Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 367:1694-1703, 2012
    • (2012) N Engl J Med , vol.367 , pp. 1694-1703
    • Flaherty, K.T.1    Infante, J.R.2    Daud, A.3
  • 13
    • 84908257665 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma
    • Long GV, Stroyakovskiy D, Gogas H, et al: Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma. N Engl J Med 371: 1877-1888, 2014
    • (2014) N Engl J Med , vol.371 , pp. 1877-1888
    • Long, G.V.1    Stroyakovskiy, D.2    Gogas, H.3
  • 14
    • 85034257560 scopus 로고    scopus 로고
    • Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: Long-term survival and safety analysis of a phase 3 study
    • Long GV, Flaherty KT, Stroyakovskiy D, et al: Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: Long-term survival and safety analysis of a phase 3 study. Ann Oncol 28:1631-1639, 2017
    • (2017) Ann Oncol , vol.28 , pp. 1631-1639
    • Long, G.V.1    Flaherty, K.T.2    Stroyakovskiy, D.3
  • 15
    • 84991059363 scopus 로고    scopus 로고
    • Dabrafenib plus trametinib in patients with previously treated BRAF(V600E)-mutant metastatic non-small cell lung cancer: An open-label, multicentre phase 2 trial
    • Planchard D, Besse B, Groen HJM, et al: Dabrafenib plus trametinib in patients with previously treated BRAF(V600E)-mutant metastatic non-small cell lung cancer: An open-label, multicentre phase 2 trial. Lancet Oncol 17:984-993, 2016
    • (2016) Lancet Oncol , vol.17 , pp. 984-993
    • Planchard, D.1    Besse, B.2    Groen, H.J.M.3
  • 16
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, et al: New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205-216, 2000
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 17
    • 77951625266 scopus 로고    scopus 로고
    • Updated response assessment criteria for high-grade gliomas: Response Assessment in Neuro-Oncology Working Group
    • Wen PY, Macdonald DR, Reardon DA, et al: Updated response assessment criteria for high-grade gliomas: Response Assessment in Neuro-Oncology Working Group. J Clin Oncol 28:1963-1972, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 1963-1972
    • Wen, P.Y.1    Macdonald, D.R.2    Reardon, D.A.3
  • 18
    • 79957516708 scopus 로고    scopus 로고
    • Response Assessment in Neuro-Oncology (a report of the RANO Group): Assessment of outcome in trials of diffuse low-grade gliomas
    • van den Bent MJ, Wefel JS, Schiff D, et al: Response Assessment in Neuro-Oncology (a report of the RANO Group): Assessment of outcome in trials of diffuse low-grade gliomas. Lancet Oncol 12: 583-593, 2011
    • (2011) Lancet Oncol , vol.12 , pp. 583-593
    • Van Den Bent, M.J.1    Wefel, J.S.2    Schiff, D.3
  • 19
    • 0020396015 scopus 로고
    • Toxicity and response criteria of the Eastern Cooperative Oncology Group
    • Oken MM, Creech RH, Tormey DC, et al: Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 5:649-655, 1982
    • (1982) Am J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.H.2    Tormey, D.C.3
  • 21
    • 85024112725 scopus 로고    scopus 로고
    • Management of treatment-related adverse events with agents targeting the MAPK pathway in patients with metastatic melanoma
    • Daud A, Tsai K: Management of treatment-related adverse events with agents targeting the MAPK pathway in patients with metastatic melanoma. Oncologist 22:823-833, 2017
    • (2017) Oncologist , vol.22 , pp. 823-833
    • Daud, A.1    Tsai, K.2
  • 22
    • 84055191090 scopus 로고    scopus 로고
    • Small-molecule MAPK inhibitors restore radio-iodine incorporation in mouse thyroid cancers with conditional BRAF activation
    • Chakravarty D, Santos E, Ryder M, et al: Small-molecule MAPK inhibitors restore radio-iodine incorporation in mouse thyroid cancers with conditional BRAF activation. J Clin Invest 121: 4700-4711, 2011
    • (2011) J Clin Invest , vol.121 , pp. 4700-4711
    • Chakravarty, D.1    Santos, E.2    Ryder, M.3
  • 23
    • 79957909599 scopus 로고    scopus 로고
    • Mu-tationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse
    • Charles RP, Iezza G, Amendola E, et al: Mu-tationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse. Cancer Res 71: 3863-3871, 2011
    • (2011) Cancer Res , vol.71 , pp. 3863-3871
    • Charles, R.P.1    Iezza, G.2    Amendola, E.3
  • 24
    • 79952180384 scopus 로고    scopus 로고
    • Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice
    • Franco AT, Malaguarnera R, Refetoff S, et al: Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. Proc Natl Acad Sci USA 108:1615-1620, 2011
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1615-1620
    • Franco, A.T.1    Malaguarnera, R.2    Refetoff, S.3
  • 25
    • 84939864059 scopus 로고    scopus 로고
    • Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations
    • Hyman DM, Puzanov I, Subbiah V, et al: Vemurafenib in multiple nonmelanoma cancers with BRAF V600 mutations. N Engl J Med 373:726-736, 2015
    • (2015) N Engl J Med , vol.373 , pp. 726-736
    • Hyman, D.M.1    Puzanov, I.2    Subbiah, V.3
  • 26
    • 84933040790 scopus 로고    scopus 로고
    • Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations
    • Ahronian LG, Sennott EM, Van Allen EM, et al: Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations. Cancer Discov 5:358-367, 2015
    • (2015) Cancer Discov , vol.5 , pp. 358-367
    • Ahronian, L.G.1    Sennott, E.M.2    Van Allen, E.M.3
  • 27
    • 84959536816 scopus 로고    scopus 로고
    • Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms
    • Johnson DB, Menzies AM, Zimmer L, et al: Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms. Eur J Cancer 51:2792-2799, 2015
    • (2015) Eur J Cancer , vol.51 , pp. 2792-2799
    • Johnson, D.B.1    Menzies, A.M.2    Zimmer, L.3
  • 28
    • 85012012638 scopus 로고    scopus 로고
    • MET-driven resistance to dual EGFR and BRAF blockade may be overcome by switching from EGFR to MET inhibition in BRAF-mutated colorectal cancer
    • Pietrantonio F, Oddo D, Gloghini A, et al: MET-driven resistance to dual EGFR and BRAF blockade may be overcome by switching from EGFR to MET inhibition in BRAF-mutated colorectal cancer. Cancer Discov 6:963-971, 2016
    • (2016) Cancer Discov , vol.6 , pp. 963-971
    • Pietrantonio, F.1    Oddo, D.2    Gloghini, A.3
  • 29
    • 84891899026 scopus 로고    scopus 로고
    • MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition
    • Wagle N, Van Allen EM, Treacy DJ, et al: MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition. Cancer Discov 4:61-68, 2014
    • (2014) Cancer Discov , vol.4 , pp. 61-68
    • Wagle, N.1    Van Allen, E.M.2    Treacy, D.J.3
  • 30
    • 84971542818 scopus 로고    scopus 로고
    • Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model
    • Danysh BP, Rieger EY, Sinha DK, et al: Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model. Oncotarget 7: 30907-30923, 2016
    • (2016) Oncotarget , vol.7 , pp. 30907-30923
    • Danysh, B.P.1    Rieger, E.Y.2    Sinha, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.