Hypoxia-increased RAGE expression regulates chemotaxis and pro-inflammatory cytokines release through nuclear translocation of NF-κ B and HIF1α in THP-1 cells

Biochemical and Biophysical Research Communications

Volumn 495, Issue 3, 2018, Pages 2282-2288

  Bai, Wei ^a   Zhou, Jing ^a   Zhou, Na ^b   Liu, Qin ^a   Cui, Jian ^a   Zou, Wei ^c   Zhang, Wei ^a  

^a NANCHANG UNIVERSITY   (China)

^b Nanchang Third Hospital   (China)

^c Maternal and Child Health Hospital of Hunan Province   (China)

Author keywords

Chemotaxis; HIF 1 ; Hypoxia; Inflammation; NF B; The receptor for advanced glycation end products (RAGE)

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CHEMOKINE RECEPTOR CCR2; CYTOKINE; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR; AUTACOID; HIF1A PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; MOK PROTEIN, HUMAN; TUMOR ANTIGEN;

ARTICLE; CELL HYPOXIA; CELL VIABILITY; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; THP-1 CELL LINE; UPREGULATION; CELL NUCLEUS; IMMUNOLOGY; NUCLEOCYTOPLASMIC TRANSPORT;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTIGENS, NEOPLASM; CELL HYPOXIA; CELL NUCLEUS; CHEMOTAXIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION MEDIATORS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; THP-1 CELLS; UP-REGULATION;

EID: 85039072544     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.12.084     Document Type: Article

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