Social cognitive dysfunction as a clinical marker: A systematic review of meta-analyses across 30 clinical conditions

Neuroscience and Biobehavioral Reviews

Volumn 84, Issue , 2018, Pages 92-99

  Cotter, Jack ^a   Granger, Kiri ^a   Backx, Rosa ^a   Hobbs, Matthew ^a   Looi, Chung Yen ^a,b   Barnett, Jennifer H ^a,c  

^a CAMBRIDGE COGNITION   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Emotion; Meta analysis; Social cognition; Systematic review; Theory of mind; Transdiagnostic

Indexed keywords

COGNITIVE DEFECT; DEVELOPMENTAL BIOLOGY; DISEASE MARKER; EMOTIONALITY; EXECUTIVE FUNCTION; FACIAL EXPRESSION; FACIAL RECOGNITION; HUMAN; MEMORY; MENTAL PERFORMANCE; MENTAL TASK; META ANALYSIS (TOPIC); PHENOTYPE; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; SOCIAL COGNITION; SYSTEMATIC REVIEW; TASK PERFORMANCE; THEORY OF MIND; ANTISOCIAL PERSONALITY DISORDER; COMPLICATION; DEVELOPMENTAL DISORDER; ENDOPHENOTYPE; MENTAL DISEASE; META ANALYSIS; NEUROLOGIC DISEASE; PSYCHOLOGY;

COGNITIVE DYSFUNCTION; DEVELOPMENTAL DISABILITIES; ENDOPHENOTYPES; FACIAL RECOGNITION; HUMANS; MENTAL DISORDERS; NERVOUS SYSTEM DISEASES; SOCIAL BEHAVIOR DISORDERS; THEORY OF MIND;

EID: 85035754020     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2017.11.014     Document Type: Review

References (96)

1. Adolphs, R., Neural systems for recognizing emotion. Curr. Opin. Neurobiol. 12:2 (2002), 169–177.
2. Aydemir, O., Akkaya, C., Uykur, B., Erol, A., Effect of facial emotion recognition on subjective psychosocial functioning in bipolar patients. Acta Psychiatr. Scand. 127:5 (2013), 412–413.
3. Babbage, D.R., Yim, J., Zupan, B., Neumann, D., Tomita, M.R., Willer, B., Meta-analysis of facial affect recognition difficulties after traumatic brain injury. Neuropsychology 25:3 (2011), 277–285.
4. Barkl, S.J., Lah, S., Harris, A.W., Williams, L.M., Facial emotion identification in early-onset and first-episode psychosis: a systematic review with meta-analysis. Schizophr. Res. 159:1 (2014), 62–69.
5. Baron-Cohen, S., Leslie, A.M., Frith, U., Does the autistic child have a theory of mind?. Cognition 21:1 (1985), 37–46.
6. Baron-Cohen, S., Wheelwright, S., Hill, J., Raste, Y., Plumb, I., The Reading the Mind in the Eyes Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J. Child Psychol. Psychiatry 42:2 (2001), 241–251.
7. Batista, S., d'Almeida, O.C., Afonso, A., Freitas, S., Macário, C., Sousa, L., Castelo-Branco, M., Santana, I., Cunha, L., Impairment of social cognition in multiple sclerosis: amygdala atrophy is the main predictor. Mult. Scler. 23:10 (2017), 1358–1366.
8. Batista, S., Alves, C., d'Almedia, O.C., Afonso, A., Félix-Morais, R., Pereira, J., Macário, C., Sousa, L., Castelo-Branco, M., Santana, I., Cunha, L., Disconnection as a mechanism for social cognition impairment in multiple sclerosis. Neurology 89:1 (2017), 38–45.
9. Beeldman, E., Raaphorst, J., Klein Twennaar, M., de Visser, M., Schmand, B.A., de Haan, R.J., The cognitive profile of ALS: a systematic review and meta-analysis update. J. Neurol. Neurosurg. Psychiatry 87:6 (2016), 611–619.
10. Bertoux, M., Hornberger, M., ‘Try to see it my way’: which theory of mind tests best distinguish bvFTD and AD?. J. Neurol. Neurosurg. Psychiatry, 86(7), 2015, 706.
11. Bertoux, M., O'Callaghan, C., Dubois, B., Hornberger, M., In two minds: executive functioning versus theory of mind in behavioural variant frontotemporal dementia. J. Neurol. Neurosurg. Psychiatry 87:3 (2016), 231–234.
12. Bishop-Fitzpatrick, L., Mazefsky, C.A., Eack, S.M., Minshew, N.J., Correlates of social functioning in autism spectrum disorder: the role of social cognition. Res. Autism Spectr. Disord. 35 (2017), 25–34.
13. Bland, A.R., Roiser, J.P., Mehta, M.A., Schei, T., Boland, H., Campbell-Meiklejohn, D.K., Emsley, R.A., Munafo, M.R., Penton-Voak, I.S., Seara-Cardoso, A., Viding, E., Voon, V., Sahakian, B.J., Robbins, T.W., Elliott, R., EMOTICOM: a neuropsychological test battery to evaluate emotion, motivation, impulsivity, and social cognition. Front. Behav. Neurosci., 10, 2016, 25.
14. Bora, E., Berk, M., Theory of mind in major depressive disorder: a meta-analysis. J. Affect. Disord. 191 (2016), 49–55.
15. Bora, E., Köse, S., Meta-analysis of theory of mind in anorexia nervosa and bulimia nervosa: a specific impairment of cognitive perspective taking in anorexia nervosa?. Int. J. Eat. Disord. 49:8 (2016), 739–749.
16. Bora, E., Meletti, S., Social cognition in temporal lobe epilepsy: a systematic review and meta-analysis. Epilepsy Behav. 60 (2016), 50–57.
17. Bora, E., Pantelis, C., Theory of mind impairments in first-episode psychosis, individuals at ultra-high risk for psychosis and in first-degree relatives of schizophrenia: systematic review and meta-analysis. Schizophr. Res. 144:1–3 (2013), 31–36.
18. Bora, E., Pantelis, C., Meta-analysis of social cognition in attention-deficit/hyperactivity disorder (ADHD): comparison with healthy controls and autistic spectrum disorder. Psychol. Med. 46:4 (2016), 699–716.
19. Bora, E., Yener, G.G., Meta-analysis of social cognition in mild cognitive impairment. J. Geriatr. Psychiatry Neurol. 30:4 (2017), 206–213.
20. Bora, E., Zorlu, N., Social cognition in alcohol use disorder: a meta-analysis. Addiction 112:1 (2017), 40–48.
21. Bora, E., Walterfang, M., Velakoulis, D., Theory of mind in behavioural-variant frontotemporal dementia and Alzheimer's disease: a meta-analysis. J. Neurol. Neurosurg. Psychiatry 86:7 (2015), 714–719.
22. Bora, E., Walterfang, M., Velakoulis, D., Theory of mind in Parkinson's disease: a meta-analysis. Behav. Brain Res. 292 (2015), 515–520.
23. Bora, E., Velakoulis, D., Walterfang, M., Meta-analysis of facial emotion recognition in behavioral variant frontotemporal dementia: comparison with alzheimer disease and healthy controls. J. Geriatr. Psychiatry Neurol. 29:4 (2016), 205–211.
24. Bora, E., Velakoulis, D., Walterfang, M., Social cognition in Huntington's disease: a meta-analysis. Behav. Brain Res. 297 (2016), 131–140.
25. Bora, E., Bartholomeusz, C., Pantelis, C., Meta-analysis of theory of mind (ToM) impairment in bipolar disorder. Psychol. Med. 46:2 (2016), 253–264.
26. Bora, E., Meta-analysis of social cognition in amyotrophic lateral sclerosis. Cortex 88 (2017), 1–7.
27. Bradley, E.R., Woolley, J.D., Oxytocin effects in schizophrenia: reconciling mixed findings and moving forward. Neurosci. Biobehav. Rev. 80 (2017), 36–56.
28. Caglar-Nazali, H.P., Corfield, F., Cardi, V., Ambwani, S., Leppanen, J., Olabintan, O., Deriziotis, S., Hadjimichalis, A., Scognamiglio, P., Eshkevari, E., Micali, N., Treasure, J., A systematic review and meta-analysis of ‘Systems for Social Processes’ in eating disorders. Neurosci. Biobehav. Rev. 42 (2014), 55–92.
29. Castellano, F., Bartoli, F., Crocamo, C., Gamba, G., Tremolada, M., Santambrogio, J., Clerici, M., Carrà, G., Facial emotion recognition in alcohol and substance use disorders: a meta-analysis. Neurosci. Biobehav. Rev. 59 (2015), 147–154.
30. Cecchetto, C., Aiello, M., D'Amico, D., Cutuli, D., Cargnelutti, D., Eleopra, R., Rumiati, R.I., Facial and bodily emotion recognition in multiple sclerosis: the role of alexithymia and other characteristics of the disease. J. Int. Neuropsychol. Soc. 20:10 (2014), 1004–1014.
31. Chung, Y.S., Barch, D., Strube, M., A meta-analysis of mentalizing impairments in adults with schizophrenia and autism spectrum disorder. Schizophr. Bull. 40:3 (2014), 602–616.
32. Cohen, J., Statistical Power Analysis for the Behavioral Sciences. 1988, Lawrence Erlbaum Associates, USA.
33. Corcoran, R., Mercer, G., Frith, C.D., Schizophrenia, symptomatology and social inference: investigating theory of mind in people with schizophrenia. Schizophr. Res. 17:1 (1995), 5–13.
34. Cotter, J., Firth, J., Enzinger, C., Kontopantelis, E., Yung, A.R., Elliott, R., Drake, R.J., Social cognition in multiple sclerosis: a systematic review and meta-analysis. Neurology 87:16 (2016), 1727–1736.
35. Cotter, J., Bartholomeusz, C., Papas, A., Allott, K., Nelson, B., Yung, A.R., Thompson, A., Examining the association between social cognition and functioning in individuals at ultra-high risk for psychosis. Aust. N. Z. J. Psychiatry 51:1 (2017), 83–92.
36. Couture, S.M., Penn, D.L., Roberts, D.L., The functional significance of social cognition in schizophrenia: a review. Schizophr. Bull. 32:Suppl. 1 (2006), S44–63.
37. Cusi, A.M., Nazarov, A., Holshausen, K., Macqueen, G.M., McKinnon, M.C., Systematic review of the neural basis of social cognition in patients with mood disorders. J. Psychiatry Neurosci. 37:3 (2012), 154–169.
38. Dalili, M.N., Penton-Voak, I.S., Harmer, C.J., Munafò, M.R., Meta-analysis of emotion recognition deficits in major depressive disorder. Psychol. Med. 45:6 (2015), 1135–1144.
39. Daros, A.R., Zakzanis, K.K., Ruocco, A.C., Facial emotion recognition in borderline personality disorder. Psychol. Med. 43:9 (2013), 1953–1963.
40. Demetriou, E.A., Lampit, A., Quintana, D.S., Naismith, S.L., Song, Y.J.C., Pye, J.E., Hickie, I., Guastella, A.J., Autism spectrum disorders: a meta-analysis of executive function. Mol. Psychiatry, 2017, 10.1038/mp.2017.75 in press.
41. Derntl, B., Habel, U., Deficits in social cognition: a marker for psychiatric disorders?. Eur. Arch. Psychiatry Clin. Neurosci. 261:Suppl. 2 (2011), S145–9.
42. Ekman, P., Friesen, W.V., Pictures of Facial Affect. 1976, Consulting Psychologists Press, Palo Alto, CA.
43. Fanning, J.R., Bell, M.D., Fiszdon, J.M., Is it possible to have impaired neurocognition but good social cognition in schizophrenia?. Schizophr. Res. 135:1–3 (2012), 68–71.
44. Fett, A.K., Viechtbauer, W., Dominguez, M.D., Penn, D.L., van Os, J., Krabbendam, L., The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: a meta-analysis. Neurosci. Biobehav. Rev. 35:3 (2011), 573–588.
45. Fioravanti, M., Bianchi, V., Cinti, M.E., Cognitive deficits in schizophrenia: an updated metanalysis of the scientific evidence. BMC Psychiatry, 12, 2012, 64.
46. Forbes, C.E., Grafman, J., The role of the human prefrontal cortex in social cognition and moral judgment. Annu. Rev. Neurosci. 33 (2010), 299–324.
47. Frith, C.D., Social cognition. Phil. Trans. R. Soc. B: Biol. Sci. 363:1499 (2008), 2033–2039.
48. Fusar-Poli, P., Nelson, B., Valmaggia, L., Yung, A.R., McGuire, P.K., Comorbid depressive and anxiety disorders in 509 individuals with an at-risk mental state: impact on psychopathology and transition to psychosis. Schizophr. Bull. 40:1 (2014), 120–131.
49. Galderisi, S., Rossi, A., Rocca, P., Bertolino, A., Mucci, A., Bucci, P., Rucci, P., Gibertoni, D., Aguglia, E., Amore, M., Bellomo, A., Biondi, M., Brugnoli, R., Dell'Osso, L., De Ronchi, D., Di Emidio, G., Di Giannantonio, M., Fagiolini, A., Marchesi, C., Monteleone, P., Oldani, L., Pinna, F., Roncone, R., Sacchetti, E., Santonastaso, P., Siracusano, A., Vita, A., Zeppegno, P., Maj, M., Italian Network for Research on Psychoses, The influence of illness-related variables, personal resources and context-related factors on real-life functioning of people with schizophrenia. World Psychiatry 13:3 (2014), 275–287.
50. García-Casal, J.A., Goñi-Imizcoz, M., Perea-Bartolomé, M.V., Soto-Pérez, F., Smith, S.J., Calvo-Simal, S., Franco-Martín, M., The efficacy of emotion recognition rehabilitation for people with Alzheimer's disease. J. Alzheimer's Dis. 57:3 (2017), 937–951.
51. Gray, H.M., Tickle-Degnen, L., A meta-analysis of performance on emotion recognition tasks in Parkinson's disease. Neuropsychology 24:2 (2010), 176–191.
52. Green, M.F., Penn, D.L., Bentall, R., Carpenter, W.T., Gaebel, W., Gur, R.C., Kring, A.M., Park, S., Silverstein, S.M., Heinssen, R., Social cognition in schizophrenia: an NIMH workshop on definitions, assessment, and research opportunities. Schizophr. Bull. 34:6 (2008), 1211–1220.
53. Green, M.F., Horan, W.P., Lee, J., Social cognition in schizophrenia. Nat. Rev. Neurosci. 16 (2015), 620–631.
54. Green, M.F., Impact of cognitive and social cognitive impairment on functional outcomes in patients with schizophrenia. J. Clin. Psychiatry 77:Suppl. 2 (2016), 8–11.
55. Gregory, C., Lough, S., Stone, V., Erzinclioglu, S., Martin, L., Baron-Cohen, S., Hodges, J.R., Theory of mind in patients with frontal variant frontotemporal dementia and Alzheimer's disease: theoretical and practical implications. Brain 125:Pt 4 (2002), 752–764.
56. Happé, F., Frith, U., The neuropsychology of autism. Brain 119:Pt 4 (1996), 1377–1400.
57. Henry, J.D., Cowan, D.G., Lee, T., Sachdev, P.S., Recent trends in testing social cognition. Curr. Opin. Psychiatry 28:2 (2015), 133–140.
58. Henry, J.D., von Hippel, W., Molenberghs, P., Lee, T., Sachdev, P.S., Clinical assessment of social cognitive function in neurological disorders. Nat. Rev. Neurol. 12:1 (2016), 28–39.
59. Higgins, J.P.T., Green, S., (eds.) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011], 2011, The Cochrane Collaboration Available from www.handbook.cochrane.org.
60. Hutchinson, A.D., Mathias, J.L., Neuropsychological deficits in frontotemporal dementia and Alzheimer's disease: a meta-analytic review. J. Neurol. Neurosurg. Psychiatry 78:9 (2007), 917–928.
61. Iacoviello, B.M., Wu, G., Alvarez, E., Huryk, K., Collins, K.A., Murrough, J.W., Iosifescu, D.V., Charney, D.S., Cognitive-emotional training as an intervention for major depressive disorder. Depress. Anxiety 31:8 (2014), 699–706.
62. Kohler, C.G., Walker, J.B., Martin, E.A., Healey, K.M., Moberg, P.J., Facial emotion perception in schizophrenia: a meta-analytic review. Schizophr. Bull. 36:5 (2010), 1009–1019.
63. Kohler, C.G., Hoffman, L.J., Eastman, L.B., Healey, K., Moberg, P.J., Facial emotion perception in depression and bipolar disorder: a quantitative review. Psychiatry Res. 188:3 (2011), 303–309.
64. Kurtz, M.M., Gagen, E., Rocha, N.B., Machado, S., Penn, D.L., Comprehensive treatments for social cognitive deficits in schizophrenia: s critical review and effect-size analysis of controlled studies. Clin. Psychol. Rev. 43 (2016), 80–89.
65. Lagravinese, G., Avanzino, L., Raffo De Ferrari, A., Marchese, R., Serrati, C., Mandich, P., Abbruzzese, G., Pelosin, E., Theory of mind is impaired in mild to moderate Huntington's Disease independently from global cognitive functioning. Front. Psychol., 8, 2017, 80.
66. Lakens, D., Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. Front. Psychol., 4, 2013, 863.
67. Lavin, C., Melis, C., Mikulan, E., Gelormini, C., Huepe, D., Ibañez, A., The anterior cingulate cortex: an integrative hub for human socially-driven interactions. Front. Neurosci., 7, 2013, 64.
68. Leppanen, J., Ng, K.W., Tchanturia, K., Treasure, J., Meta-analysis of the effects of intranasal oxytocin on interpretation and expression of emotions. Neurosci. Biobehav. Rev. 78 (2017), 125–144.
69. Lindquist, K.A., Wager, T.D., Kober, H., Bliss-Moreau, E., Barrett, L.F., The brain basis of emotion: a meta-analytic review. Behav. Brain Sci. 35:3 (2012), 121–143.
70. Mehta, U.M., Thirthalli, J., Subbakrishna, D.K., Gangadhar, B.N., Eack, S.M., Keshavan, M.S., Social and neuro-cognition as distinct cognitive factors in schizophrenia: a systematic review. Schizophr. Res. 148:1–3 (2013), 3–11.
71. Mercedes Perez-Rodriguez, M., Mahon, K., Russo, M., Ungar, A.K., Burdick, K.E., Oxytocin and social cognition in affective and psychotic disorders. Eur. Neuropsychopharmacol. 25:2 (2015), 265–282.
72. Meyer-Lindenberg, A., Domes, G., Kirsch, P., Heinrichs, M., Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine. Nat. Rev. Neurosci. 12:9 (2011), 524–538.
73. Mitchell, R.L., Phillips, L.H., The overlapping relationship between emotion perception and theory of mind. Neuropsychologia 70 (2015), 1–10.
74. Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., PRISMA Group, Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ, 339, 2009, b2535.
75. Molenberghs, P., Johnson, H., Henry, J.D., Mattingley, J.B., Understanding the minds of others: a neuroimaging meta-analysis. Neurosci. Biobehav. Rev. 65 (2016), 276–291.
76. Nilsson, K.K., de López, K.J., Theory of mind in children with specific language impairment: a systematic review and meta-analysis. Child Dev. 87:1 (2016), 143–153.
77. Patriquin, M.A., DeRamus, T., Libero, L.E., Laird, A., Kana, R.K., Neuroanatomical and neurofunctional markers of social cognition in autism spectrum disorder. Hum. Brain Map. 37:11 (2016), 3957–3978.
78. Penton-Voak, I.S., Bate, H., Lewis, G., Munafò, M.R., Effects of emotion perception training on mood in undergraduate students: randomised controlled trial. Br. J. Psychiatry 201:1 (2012), 71–72.
79. Penton-Voak, I., Munafo, M., Looi, C.Y., Biased facial emotion perception in mental health disorders: a possible target for psychological intervention?. Curr. Dir. Psychol. Sci. 26:3 (2017), 294–301.
80. Phillips, L.H., Henry, J.D., Scott, C., Summers, F., Whyte, M., Cook, M., Specific impairments of emotion perception in multiple sclerosis. Neuropsychology 25:1 (2011), 131–136.
81. Pinkham, A.E., Penn, D.L., Green, M.F., Harvey, P.D., Social cognition psychometric evaluation: results of the initial psychometric study. Schizophr. Bull. 42:2 (2016), 494–504.
82. Plana, I., Lavoie, M.A., Battaglia, M., Achim, A.M., A meta-analysis and scoping review of social cognition performance in social phobia, posttraumatic stress disorder and other anxiety disorders. J. Anxiety Disord. 28:2 (2014), 169–177.
83. Poletti, M., Enrici, I., Adenzato, M., Cognitive and affective Theory of Mind in neurodegenerative diseases: neuropsychological, neuroanatomical and neurochemical levels. Neurosci. Biobehav. Rev. 36:9 (2012), 2147–2164.
84. Prakash, R.S., Snook, E.M., Lewis, J.M., Motl, R.W., Kramer, A.F., Cognitive impairments in relapsing-remitting multiple sclerosis: a meta-analysis. Mult. Scler. 14:9 (2008), 1250–1261.
85. Preti, A., Melis, M., Siddi, S., Vellante, M., Doneddu, G., Fadda, R., Oxytocin and autism: a systematic review of randomized controlled trials. J. Child Adolesc. Psychopharmacol. 24:2 (2014), 54–68.
86. Richman, M.J., Unoka, Z., Mental state decoding impairment in major depression and borderline personality disorder: meta-analysis. Br. J. Psychiatry 207:6 (2015), 483–489.
87. Savla, G.N., Vella, L., Armstrong, C.C., Penn, D.L., Twamley, E.W., Deficits in domains of social cognition in schizophrenia: a meta-analysis of the empirical evidence. Schizophr. Bull. 39:5 (2013), 979–992.
88. Seeley, W.W., Crawford, R.K., Zhou, J., Miller, B.L., Greicius, M.D., Neurodegenerative diseases target large-scale human brain networks. Neuron 62:1 (2009), 42–52.
89. Siegert, R.J., Abernethy, D.A., Depression in multiple sclerosis: a review Journal of Neurology. Neurosurg. Psychiatry 76:4 (2005), 469–475.
90. Stewart, E., Catroppa, C., Lah, S., Theory of mind in patients with epilepsy: a systematic review and meta-analysis. Neuropsychol. Rev. 26:1 (2016), 3–24.
91. Trevisan, D.A., Birmingham, E., Are emotion recognition abilities related to everyday social functioning in ASD? A meta-analysis. Res. Autism Spectr. Disord. 32 (2016), 24–42.
92. Ulfvebrand, S., Birgegård, A., Norring, C., Högdahl, L., von Hausswolff-Juhlin, Y., Psychiatric comorbidity in women and men with eating disorders results from a large clinical database. Psychiatry Res. 230:2 (2015), 294–299.
93. van Donkersgoed, R.J., Wunderink, L., Nieboer, R., Aleman, A., Pijnenborg, G.H., Social cognition in individuals at ultra-high risk for psychosis: a meta-analysis. PLoS One, 10(10), 2015, e0141075.
94. Van Overwalle, F., Social cognition and the brain: a meta-analysis. Hum. Brain Map. 30:3 (2009), 829–858.
95. Vaskinn, A., Sundet, K., Østefjells, T., Nymo, K., Melle, I., Ueland, T., Reading emotions from body movement: a generalized impairment in schizophrenia. Front. Psychol., 6, 2016, 2058.
96. Yirmiya, N., Erel, O., Shaked, M., Solomonica-Levi, D., Meta-analyses comparing theory of mind abilities of individuals with autism, individuals with mental retardation, and normally developing individuals. Psychol. Bull. 124:3 (1998), 283–307.