Decreased Serum Brain-Derived Neurotrophic Factor May Indicate the Development of Poststroke Depression in Patients with Acute Ischemic Stroke: A Meta-Analysis

Journal of Stroke and Cerebrovascular Diseases

Volumn 27, Issue 3, 2018, Pages 709-715

  Xu, Hong Bo ^a,c   Xu, Yu Hong ^b,c   He, Ying ^b   Xue, Fang ^a   Wei, Jing ^a   Zhang, Haigang ^a   Wu, Jinglan ^a  

^a The 6th Affiliated Hospital of Shenzhen University Health Science Center   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c NONE

Author keywords

BDNF; biomarker; meta analysis; Poststroke depression

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BIOLOGICAL MARKER; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN;

ARTICLE; BRAIN ISCHEMIA; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; HIGH RISK PATIENT; HUMAN; META ANALYSIS; POST-STROKE DEPRESSION; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; SYSTEMATIC REVIEW; BLOOD; CEREBROVASCULAR ACCIDENT; CHI SQUARE DISTRIBUTION; COMPLICATION; DEPRESSION; DOWN REGULATION; PREDICTIVE VALUE; PROGNOSIS; PSYCHOLOGY; RISK FACTOR;

BIOMARKERS; BRAIN ISCHEMIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHI-SQUARE DISTRIBUTION; DEPRESSION; DOWN-REGULATION; HUMANS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK FACTORS; STROKE;

EID: 85034569130     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2017.10.003     Document Type: Article

References (36)

1. Hackett, M.L., Pickles, K., Part I: frequency of depression after stroke: an updated systematic review and meta-analysis of observational studies. Int J Stroke 9 (2014), 1017–1025.
2. Brown, C., Hasson, H., Thyselius, V., et al. Post-stroke depression and functional independence: a conundrum. Acta Neurol Scand 126 (2012), 45–51.
3. Robinson, R.G., Jorge, R.E., Post-stroke depression: a review. Am J Psychiatry 173 (2016), 221–231.
4. Fuentes, B., Ortiz, X., Sanjose, B., et al. Post-stroke depression: can we predict its development from the acute stroke phase?. Acta Neurol Scand 120 (2009), 150–156.
5. Krishnan, V., Nestler, E.J., The molecular neurobiology of depression. Nature 455 (2008), 894–902.
6. Castren, E., Rantamaki, T., Role of brain-derived neurotrophic factor in the aetiology of depression: implications for pharmacological treatment. CNS Drugs 24 (2010), 1–7.
7. Li, J., Zhao, Y.D., Zeng, J.W., et al. Serum brain-derived neurotrophic factor levels in post-stroke depression. J Affect Disord 168 (2014), 373–379.
8. Yang, L., Zhang, Z., Sun, D., et al. Low serum BDNF may indicate the development of PSD in patients with acute ischemic stroke. Int J Geriatr Psychiatry 26 (2011), 495–502.
9. Zhou, Z., Lu, T., Xu, G., et al. Decreased serum brain-derived neurotrophic factor (BDNF) is associated with post-stroke depression but not with BDNF gene Val66Met polymorphism. Clinical Clin Chem Lab Med 49 (2011), 185–189.
10. Moher, D., Liberati, A., Tetzlaff, J., et al. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement. PLoS Med, 6, 2009 e1000097.
11. Wells, G., Shea, B., O'Connell, D., et al. The Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Hospital Research Institute web site; Available at: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp. (Accessed 24 May 2017)
12. Wan, X., Wang, W., Liu, J., et al. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol, 14, 2014, 135.
13. Luo, D., Wan, X., Liu, J., et al. Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range. Stat Methods Med Res, 2016 https://doi.org/10.1177/0962280216669183.
14. Mitchell, M., Muftakhidinov, B., Winchen, T., et al. Engauge Digitizer software. Available at: http://markummitchell.github.io/engauge-digitizer. (Accessed 24 May 2017)
15. Patsopoulos, N.A., Evangelou, E., Ioannidis, J.P., Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol 37 (2008), 1148–1157.
16. Li, J., Zou, D.H., Xu, B.C., et al. Correlation between serum brain-derived neurotrophic factor level and depression after ischemic stroke. Int J Cerebrovasc Dis 24 (2016), 815–818.
17. Liu, W., Ge, T., Leng, Y., et al. The role of neural plasticity in depression: from hippocampus to prefrontal cortex. Neural Plast, 2017, 2017, 6871089.
18. Sen, S., Duman, R., Sanacora, G., Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry 64 (2008), 527–532.
19. Brunoni, A.R., Lopes, M., Fregni, F., A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol 11 (2008), 1169–1180.
20. Golden, E., Emiliano, A., Maudsley, S., et al. Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging. PLoS ONE, 5, 2010 e10099.
21. Schabitz, W.R., Sommer, C., Zoder, W., et al. Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia. Stroke 31 (2000), 2212–2217.
22. Han, J., Pollak, J., Yang, T., et al. Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic stroke. Stroke 43 (2012), 1918–1924.
23. Pikula, A., Beiser, A.S., Chen, T.C., et al. Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study. Stroke 44 (2013), 2768–2775.
24. Loubinoux, I., Kronenberg, G., Endres, M., et al. Post-stroke depression: mechanisms, translation and therapy. J Cell Mol Med 16 (2012), 1961–1969.
25. Strbian, D., Durukan, A., Pitkonen, M., et al. The blood-brain barrier is continuously open for several weeks following transient focal cerebral ischemia. Neuroscience 153 (2008), 175–181.
26. Pan, W., Banks, W.A., Fasold, M.B., et al. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37 (1998), 1553–1561.
27. Jimenez, I., Sobrino, T., Rodriguez-Yanez, M., et al. High serum levels of leptin are associated with post-stroke depression. Psychol Med 39 (2009), 1201–1209.
28. Noonan, K., Carey, L.M., Crewther, S.G., Meta-analyses indicate associations between neuroendocrine activation, deactivation in neurotrophic and neuroimaging markers in depression after stroke. J Stroke Cerebrovasc Dis 22 (2013), e124–e135.
29. Numakawa, T., Yokomaku, D., Richards, M., et al. Functional interactions between steroid hormones and neurotrophin BDNF. World J Biol Chem 1 (2010), 133–143.
30. You, Z., Luo, C., Zhang, W., et al. Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: involvement in depression. Behav Brain Res 225 (2011), 135–141.
31. Kim, J.M., Stewart, R., Kim, S.W., et al. BDNF genotype potentially modifying the association between incident stroke and depression. Neurobiol Aging 29 (2008), 789–792.
32. Dai, M.H., Li, D.Q., Han, Y., Effect of venlafaxine on cognitive function and hippocampal brain-derived neurotrophic factor expression in rats with post-stroke depression. Zhejiang Da Xue Xue Bao Yi Xue Ban 40 (2011), 527–534.
33. Gelenberg, A.J., Hopkins, H.S., Assessing and treating depression in primary care medicine. Am J Med 120 (2007), 105–108.
34. Dwyer Hollender, K., Screening, diagnosis, and treatment of post-stroke depression. J Neurosci Nurs 46 (2014), 135–141.
35. Ramasubbu, R., Therapy for prevention of post-stroke depression. Expert Opin Pharmacother 12 (2011), 2177–2187.
36. Salter, K.L., Foley, N.C., Zhu, L., et al. Prevention of poststroke depression: does prophylactic pharmacotherapy work?. J Stroke Cerebrovasc Dis 22 (2013), 1243–1251.