Decreased serum brain-derived neurotrophic factor (BDNF) is associated with post-stroke depression but not with BDNF gene Val66Met polymorphism

Clinical Chemistry and Laboratory Medicine

Volumn 49, Issue 2, 2011, Pages 185-189

  Zhou, Zhiming ^a,b   Lu, Tingting ^a   Xu, Gelin ^a   Yue, Xuanye ^a,c   Zhu, Wusheng ^a   Ma, Minmin ^a   Liu, Wenhua ^a   Zhu, Shuanggen ^a,d   Liu, Xinfeng ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b WANNAN MEDICAL COLLEGE   (China)

^c HUBEI UNIVERSITY OF MEDICINE   (China)

^d ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

brain derived neurotrophic factor; neurotrophins; polymorphism; post stroke depression; stroke

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE SEVERITY; FEMALE; FOLLOW UP; GENETIC POLYMORPHISM; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POSTSTROKE DEPRESSION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN-DERIVED NEUROTROPHIC FACTOR; CASE-CONTROL STUDIES; DEPRESSIVE DISORDER; FEMALE; FOLLOW-UP STUDIES; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; STROKE; YOUNG ADULT;

ANIMALIA;

EID: 79952094919     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2011.039     Document Type: Article

References (35)

1. Hackett ML, Yapa C, Parag V, Anderson CS. Frequency of depression after stroke: a systematic review of observational studies. Stroke 2005;36:1330-40.
2. Sackley C, Brittle N, Patel S, Ellins J, Scott M, Wright C, et al. The prevalence of joint contractures, pressure sores, painful shoulder, other pain, falls, and depression in the year after a severely disabling stroke. Stroke 2008;39:3329-34.
3. Astrom M, Adolfsson R, Asplund K. Major depression in stroke patients. A 3-year longitudinal study. Stroke 1993;24:976-82.
4. Fuh JL, Liu HC, Wang SJ, Liu CY, Wang PN. Poststroke depression among the Chinese elderly in a rural community. Stroke 1997;28:1126-9.
5. Carota A, Berney A, Aybek S, Iaria G, Staub F, Ghika-Schmid F, et al. A prospective study of predictors of poststroke depression. Neurology 2005;64:428-33. (Pubitemid 40189858)
6. Nannetti L, Paci M, Pasquini J, Lombardi B, Taiti PG. Motor and functional recovery in patients with post-stroke depression. Disabil Rehabil 2005;27:170-5. (Pubitemid 40468157)
7. Gainotti G, Antonucci G, Marra C, Paolucci S. Relation between depression after stroke, antidepressant therapy, and functional recovery. J Neurol Neurosurg Psychiatry 2001;71: 258-61. (Pubitemid 32675158)
8. Fang J, Cheng Q. Etiological mechanisms of post-stroke depression: a review. Neurol Res 2009;31:904-9.
9. Guillin O, Griffon N, Diaz J, Le Foll B, Bezard E, Gross C, et al. Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway. Int Rev Neurobiol 2004;59: 425-44. (Pubitemid 39752423)
10. Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry 2008;64:527-32.
11. Duman RS, Monteggia LM. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 2006;59:1116-27.
12. Karege F, Perret G, Bondolfi G, Schwald M, Bertschy G, Aubry JM. Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res 2002;109:143-8. (Pubitemid 34258493)
13. Bocchio-Chiavetto L, Bagnardi V, Zanardini R, Molteni R, Gabriela Nielsen M, Placentino A, et al. Serum and plasma BDNF levels in major depression: a replication study and meta-analyses. World J Biol Psychiatry 2010;11:763-73.
14. Karege F, Schwald M, Cisse M. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 2002;328:261-4. (Pubitemid 34876661)
15. Weickert CS, Hyde TM, Lipska BK, Herman MM, Weinberger DR, Kleinman JE. Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Mol Psychiatry 2003;8:592-610. (Pubitemid 36898018)
16. Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003;112:257-69. (Pubitemid 36144114)
17. Cattaneo A, Bocchio-Chiavetto L, Zanardini R, Marchina E, Bellotti D, Milanesi E, et al. BDNF Val66Met polymorphism and protein levels in amniotic fluid. BMC Neurosci 2010;11:16.
18. Stroke-1989. Recommendations on stroke prevention, diagnosis, and therapy. Report of the WHO Task Force on Stroke and other Cerebrovascular Disorders. Stroke 1989;20:1407-31.
19. Brott T, Adams HP Jr, Olinger CP, Marler JR, Barsan WG, Biller J, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989;20:864-70. (Pubitemid 19188240)
20. Uyttenboogaart M, Stewart RE, Vroomen PC, De Keyser J, Luijckx GJ. Optimizing cutoff scores for the Barthel index and the modified Rankin scale for defining outcome in acute stroke trials. Stroke 2005;36:1984-7. (Pubitemid 41266538)
21. Endicott J, Cohen J, Nee J, Fleiss J, Sarantakos S. Hamilton depression rating scale. Extracted from regular and change versions of the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 1981;38:98-103.
22. Czeh B, Michaelis T, Watanabe T, Frahm J, de Biurrun G, van Kampen M, et al. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci USA 2001;98:12796-801. (Pubitemid 33020024)
23. Karege F, Bondolfi G, Gervasoni N, Schwald M, Aubry JM, Bertschy G. Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biol Psychiatry 2005;57:1068-72. (Pubitemid 40613035)
24. Matrisciano F, Bonaccorso S, Ricciardi A, Scaccianoce S, Panaccione I, Wang L, et al. Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine. J Psychiatr Res 2009;43:247-54.
25. Lang UE, Hellweg R, Sander T, Gallinat J. The Met allele of the BDNF Val66Met polymorphism is associated with increased BDNF serum concentrations. Mol Psychiatry 2009; 14:120-2.
26. Piccinni A, Marazziti D, Catena M, Domenici L, Del Debbio A, Bianchi C, et al. Plasma and serum brain-derived neurotrophic factor (BDNF) in depressed patients during 1 year of antidepressant treatments. J Affect Disord 2008;105:279-83. (Pubitemid 350245688)
27. Rantamaki T, Knuuttila JE, Hokkanen ME, Castren E. The effects of acute and long-term lithium treatments on trkB neurotrophin receptor activation in the mouse hippocampus and anterior cingulate cortex. Neuropharmacology 2006;50:421-7. (Pubitemid 43209038)
28. Jimenez I, Sobrino T, Rodriguez-Yanez M, Pouso M, Cristobo I, Sabucedo M, et al. High serum levels of leptin are associated with post-stroke depression. Psychol Med 2009;39:1201-9.
29. Matsumoto T, Rauskolb S, Polack M, Klose J, Kolbeck R, Korte M, et al. Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat Neurosci 2008;11:131-3. (Pubitemid 351170498)
30. Ozan E, Okur H, Eker C, Eker OD, Gonul AS, Akarsu N. The effect of depression, BDNF gene val66met polymorphism and gender on serum BDNF levels. Brain Res Bull 2010;81:61-5.
31. Jiang H, Wang R, Liu Y, Zhang Y, Chen ZY. BDNF Val66Met polymorphism is associated with unstable angina. Clin Chim Acta 2009;400:3-7.
32. Terracciano A, Martin B, Ansari D, Tanaka T, Ferrucci L, Maudsley S, et al. Plasma BDNF concentration, Val66Met genetic variant and depression-related personality traits. Genes Brain Behav 2010;9:512-8.
33. Lee BH, Kim YK. Reduced platelet BDNF level in patients with major depression. Prog Neuropsychopharmacol Biol Psychiatry 2009;33:849-53.
34. Fujimura H, Altar CA, Chen R, Nakamura T, Nakahashi T, Kambayashi J, et al. Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thromb Haemost 2002;87:728-34. (Pubitemid 34302963)
35. Gervasoni N, Aubry JM, Bondolfi G, Osiek C, Schwald M, Bertschy G, et al. Partial normalization of serum brain-derived neurotrophic factor in remitted patients after a major depressive episode. Neuropsychobiology 2005;51:234-8. (Pubitemid 40976406)