Drug abusers have impaired cerebral oxygenation and cognition during exercise

PLoS ONE

Volumn 12, Issue 11, 2017, Pages

  Grandjean da Costa, Kell ^a   Soares Rachetti, Vanessa ^a   Quirino Alves Da Silva, Weslley ^a   Aranha Rego Cabral, Daniel ^a   Gomes da Silva Machado, Daniel ^a,b   Caldas Costa, Eduardo ^a   Menezes Forti, Rodrigo ^c,d   Coelho Mesquita, Rickson ^c,d   Mohamed Elsangedy, Hassan ^a   Hideki Okano, Alexandre ^b,e   Bodnariuc Fontes, Eduardo ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^b STATE UNIVERSITY OF LONDRINA   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

^d Brazilian Institute of Neuroscience and Neurotechnology (BRAINN)   (Brazil)

^e UNIVERSIDADE FEDERAL DO ABC   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

OXYHEMOGLOBIN;

ADULT; ARTICLE; BICYCLE ERGOMETRY; BRAIN BLOOD FLOW; BRAIN TISSUE; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CRAVING; CROSS-SECTIONAL STUDY; DRUG DEPENDENCE; EXERCISE INTENSITY; EXERCISE TEST; HEMODYNAMICS; HUMAN; IMPAIRED CEREBRAL OXYGENATION; KINESIOTHERAPY; MEASUREMENT; MENTAL PERFORMANCE; OXYGEN CONSUMPTION; PERCEPTION; PREFRONTAL CORTEX; RESPONSE TIME; STROOP TEST; TISSUE OXYGENATION; VALIDATION STUDY; ADOLESCENT; BRAIN; COGNITION; EXERCISE; FEMALE; MALE; METABOLISM; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; BRAIN; COGNITION; EXERCISE; FEMALE; HUMANS; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; YOUNG ADULT;

EID: 85033602536     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0188030     Document Type: Article

References (53)

1. Ali SF, Onaivi ES, Dodd PR, Cadet JL, Schenk S, Kuhar MJ, et al. Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists. Curr Neuropharmacol. 2011 Mar; 9(1):2–7. https://doi.org/10.2174/157015911795017245 PMID: 21886551
2. Hasin DS, O’Brien CP, Auriacombe M, Borges G, Bucholz K, Budney A, et al. DSM-5 Criteria for Substance Use Disorders: Recommendations and Rationale. Am J Psychiatry. 2013 Aug 1; 170(8):834–51. https://doi.org/10.1176/appi.ajp.2013.12060782 PMID: 23903334
3. Volkow ND, Li T-K. Drugs and alcohol: treating and preventing abuse, addiction and their medical consequences. Pharmacol Ther. 2005 Oct; 108(1):3–17. https://doi.org/10.1016/j.pharmthera.2005.06.021 PMID: 16098597
4. Volkow ND, Koob G. Brain disease model of addiction: why is it so controversial? Lancet Psychiatry. 2015 Aug; 2(8):677–9. https://doi.org/10.1016/S2215-0366(15)00236-9 PMID: 26249284
5. Hart CL. Viewing addiction as a brain disease promotes social injustice. Nat Hum Behav. 2017 Feb 17; 1:0055.
6. Kelley AE, Berridge KC. The neuroscience of natural rewards: relevance to addictive drugs. J Neurosci Off J Soc Neurosci. 2002 May 1; 22(9):3306–11.
7. Goldstein RZ, Volkow ND. Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am J Psychiatry. 2002 Oct; 159(10):1642–52. https://doi.org/10.1176/appi.ajp.159.10.1642 PMID: 12359667
8. Goldstein RZ, Volkow ND. Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nat Rev Neurosci. 2011 Nov; 12(11):652–69. https://doi.org/10.1038/nrn3119 PMID: 22011681
9. Asensio S, Morales JL, Senabre I, Romero MJ, Beltran MA, Flores-Bellver M, et al. Magnetic resonance imaging structural alterations in brain of alcohol abusers and its association with impulsivity. Addict Biol. 2016 Jul; 21(4):962–71. https://doi.org/10.1111/adb.12257 PMID: 25988724
10. Pahng AR, McGinn MA, Paulsen RI, Edwards S. The Prefrontal Cortex as a Critical Gate of Negative Affect and Motivation in Alcohol Use Disorder. Curr Opin Behav Sci. 2017 Feb; 13:139–43. https://doi.org/10.1016/j.cobeha.2016.11.004 PMID: 28111628
11. Schecklmann M, Ehlis A-C, Plichta MM, Boutter HK, Metzger FG, Fallgatter AJ. Altered frontal brain oxygenation in detoxified alcohol dependent patients with unaffected verbal fluency performance. Psychiatry Res. 2007 Nov 15; 156(2):129–38. https://doi.org/10.1016/j.pscychresns.2007.01.009 PMID: 17888635
12. Wang J, Fan Y, Dong Y, Ma M, Ma Y, Dong Y, et al. Alterations in Brain Structure and Functional Connectivity in Alcohol Dependent Patients and Possible Association with Impulsivity. PloS One. 2016; 11 (8):e0161956. https://doi.org/10.1371/journal.pone.0161956 PMID: 27575491
13. Volkow ND, Koob GF, McLellan AT. Neurobiologic Advances from the Brain Disease Model of Addiction. N Engl J Med. 2016 Jan 28; 374(4):363–71. https://doi.org/10.1056/NEJMra1511480 PMID: 26816013
14. Bechara A. Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. Nat Neurosci. 2005 Nov; 8(11):1458–63. https://doi.org/10.1038/nn1584 PMID: 16251988
15. Buchowski MS, Meade NN, Charboneau E, Park S, Dietrich MS, Cowan RL, et al. Aerobic exercise training reduces cannabis craving and use in non-treatment seeking cannabis-dependent adults. PloS One. 2011; 6(3):e17465. https://doi.org/10.1371/journal.pone.0017465 PMID: 21408154
16. Wang D, Wang Y, Wang Y, Li R, Zhou C. Impact of physical exercise on substance use disorders: a meta-analysis. PloS One. 2014; 9(10):e110728. https://doi.org/10.1371/journal.pone.0110728 PMID: 25330437
17. Roessler KK. Exercise treatment for drug abuse—a Danish pilot study. Scand J Public Health. 2010 Aug; 38(6):664–9. https://doi.org/10.1177/1403494810371249 PMID: 20529968
18. Raichlen DA, Polk JD. Linking brains and brawn: exercise and the evolution of human neurobiology. Proc Biol Sci. 2013 Jan 7; 280(1750):20122250. https://doi.org/10.1098/rspb.2012.2250 PMID: 23173208
19. Bediz CS, Oniz A, Guducu C, Ural Demirci E, Ogut H, Gunay E, et al. Acute Supramaximal Exercise Increases the Brain Oxygenation in Relation to Cognitive Workload. Front Hum Neurosci. 2016; 10:174. https://doi.org/10.3389/fnhum.2016.00174 PMID: 27148022
20. Erickson KI, Kramer AF. Aerobic exercise effects on cognitive and neural plasticity in older adults. Br J Sports Med. 2009 Jan; 43(1):22–4. https://doi.org/10.1136/bjsm.2008.052498 PMID: 18927158
21. Jung R, Moser M, Baucsek S, Dern S, Schneider S. Activation patterns of different brain areas during incremental exercise measured by near-infrared spectroscopy. Exp Brain Res. 2015 Apr; 233(4):1175–80. https://doi.org/10.1007/s00221-015-4201-4 PMID: 25579663
22. Rooks CR, Thom NJ, McCully KK, Dishman RK. Effects of incremental exercise on cerebral oxygenation measured by near-infrared spectroscopy: a systematic review. Prog Neurobiol. 2010 Oct; 92 (2):134–50. https://doi.org/10.1016/j.pneurobio.2010.06.002 PMID: 20542078
23. Balady GJ, Arena R, Sietsema K, Myers J, Coke L, Fletcher GF, et al. Clinician’s Guide to cardiopulmonary exercise testing in adults: a scientific statement from the American Heart Association. Circulation. 2010 Jul 13; 122(2):191–225. https://doi.org/10.1161/CIR.0b013e3181e52e69 PMID: 20585013
24. Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982; 14(5):377–81. PMID: 7154893
25. Batista EK, Klauss J, Fregni F, Nitsche MA, Nakamura-Palacios EM. A Randomized Placebo-Controlled Trial of Targeted Prefrontal Cortex Modulation with Bilateral tDCS in Patients with Crack-Cocaine Dependence. Int J Neuropsychopharmacol [Internet]. 2015 Jun 10 [cited 2016 Sep 16];18(12). Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675977/
26. Thompson PD, Arena R, Riebe D, Pescatello LS, American College of Sports Medicine. ACSM’s new preparticipation health screening recommendations from ACSM’s guidelines for exercise testing and prescription, ninth edition. Curr Sports Med Rep. 2013 Aug; 12(4):215–7. https://doi.org/10.1249/JSR. 0b013e31829a68cf PMID: 23851406
27. Humeniuk R, Ali R, Babor T, Souza-Formigoni MLO, de Lacerda RB, Ling W, et al. A randomized controlled trial of a brief intervention for illicit drugs linked to the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in clients recruited from primary health-care settings in four countries. Addict Abingdon Engl. 2012 May; 107(5):957–66.
28. Sussner BD, Smelson DA, Rodrigues S, Kline A, Losonczy M, Ziedonis D. The validity and reliability of a brief measure of cocaine craving. Drug Alcohol Depend. 2006 Jul 27; 83(3):233–7. https://doi.org/10.1016/j.drugalcdep.2005.11.022 PMID: 16384655
29. Araujo RB, Pedroso RS, Castro M da GT de. Transcultural adaptation into Portuguese language of the Cocaine Craving Questionnaire—Brief. Arch Clin Psychiatry São Paulo. 2010; 37(5):195–8.
30. Dafoe W. Principles of Exercise Testing and Interpretation. Can J Cardiol. 2007 Mar 15; 23(4):274.
31. Ekkekakis P. Illuminating the black box: investigating prefrontal cortical hemodynamics during exercise with near-infrared spectroscopy. J Sport Exerc Psychol. 2009 Aug; 31(4):505–53. PMID: 19842545
32. Huppert TJ, Diamond SG, Franceschini MA, Boas DA. HomER: a review of time-series analysis methods for near-infrared spectroscopy of the brain. Appl Opt. 2009 Apr 1; 48(10):D280–298. PMID: 19340120
33. Schack B, Chen AC, Mescha S, Witte H. Instantaneous EEG coherence analysis during the Stroop task. Clin Neurophysiol Off J Int Fed Clin Neurophysiol. 1999 Aug; 110(8):1410–26.
34. Lassen NA. Control of cerebral circulation in health and disease. Circ Res. 1974 Jun; 34(6):749–60. PMID: 4598993
35. Madsen PL, Schmidt JF, Wildschiødtz G, Friberg L, Holm S, Vorstrup S, et al. Cerebral O2 metabolism and cerebral blood flow in humans during deep and rapid-eye-movement sleep. J Appl Physiol Bethesda Md 1985. 1991 Jun; 70(6):2597–601.
36. Ogoh S, Ainslie PN. Cerebral blood flow during exercise: mechanisms of regulation. J Appl Physiol Bethesda Md 1985. 2009 Nov; 107(5):1370–80.
37. Perrey S. Non-invasive NIR spectroscopy of human brain function during exercise. Methods San Diego Calif. 2008 Aug; 45(4):289–99.
38. Tempest GD, Davranche K, Brisswalter J, Perrey S, Radel R. The differential effects of prolonged exercise upon executive function and cerebral oxygenation. Brain Cogn. 2017 Apr; 113:133–41. https://doi.org/10.1016/j.bandc.2017.02.001 PMID: 28235695
39. Volkow ND, Fowler JS, Wang GJ, Baler R, Telang F. Imaging dopamine’s role in drug abuse and addiction. Neuropharmacology. 2009; 56 Suppl 1:3–8.
40. Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: exercise effects on brain and cognition. Nat Rev Neurosci. 2008 Jan; 9(1):58–65. https://doi.org/10.1038/nrn2298 PMID: 18094706
41. Rosenbloom MH, Schmahmann JD, Price BH. The functional neuroanatomy of decision-making. J Neu-ropsychiatry Clin Neurosci. 2012; 24(3):266–77. https://doi.org/10.1176/appi.neuropsych.11060139 PMID: 23037641
42. Hillman CH, Drobes DJ. Physical Activity and Cognitive Control: Implications for Drug Abuse. Child Dev Perspect. 2012 Dezembro; 6(4):367–73.
43. Robertson CV, Marino FE. A role for the prefrontal cortex in exercise tolerance and termination. J Appl Physiol Bethesda Md 1985. 2016 Feb 15; 120(4):464–6.
44. Tempest G, Parfitt G. Self-reported tolerance influences prefrontal cortex hemodynamics and affective responses. Cogn Affect Behav Neurosci. 2016 Feb; 16(1):63–71. https://doi.org/10.3758/s13415-015-0374-3 PMID: 26337703
45. Damasio AR. The somatic marker hypothesis and the possible functions of the prefrontal cortex. Philos Trans R Soc Lond B Biol Sci. 1996 Oct 29; 351(1346):1413–20. https://doi.org/10.1098/rstb.1996.0125 PMID: 8941953
46. Ochsner KN, Ray RD, Cooper JC, Robertson ER, Chopra S, Gabrieli JDE, et al. For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion. NeuroImage. 2004 Oct; 23(2):483–99. https://doi.org/10.1016/j.neuroimage.2004.06.030 PMID: 15488398
47. Verdejo-Garcia A, Clark L, Dunn BD. The role of interoception in addiction: a critical review. Neurosci Biobehav Rev. 2012 Sep; 36(8):1857–69. https://doi.org/10.1016/j.neubiorev.2012.05.007 PMID: 22659642
48. Petzinger GM, Walsh JP, Akopian G, Hogg E, Abernathy A, Arevalo P, et al. Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. J Neurosci Off J Soc Neurosci. 2007 May 16; 27(20):5291–300.
49. Greenwood BN, Foley TE, Le TV, Strong PV, Loughridge AB, Day HEW, et al. Long-term voluntary wheel running is rewarding and produces plasticity in the mesolimbic reward pathway. Behav Brain Res. 2011 Mar 1; 217(2):354–62. https://doi.org/10.1016/j.bbr.2010.11.005 PMID: 21070820
50. Wang D, Zhou C, Zhao M, Wu X, Chang Y-K. Dose-response relationships between exercise intensity, cravings, and inhibitory control in methamphetamine dependence: An ERPs study. Drug Alcohol Depend. 2016 Apr 1; 161:331–9. https://doi.org/10.1016/j.drugalcdep.2016.02.023 PMID: 26946990
51. Mekari S, Fraser S, Bosquet L, Bonnéry C, Labelle V, Pouliot P, et al. The relationship between exercise intensity, cerebral oxygenation and cognitive performance in young adults. Eur J Appl Physiol. 2015 Oct; 115(10):2189–97. https://doi.org/10.1007/s00421-015-3199-4 PMID: 26063061
52. Gomez-Pinilla F, Hillman C. The Influence of Exercise on Cognitive Abilities. Compr Physiol. 2013 Jan; 3(1):403–28. https://doi.org/10.1002/cphy.c110063 PMID: 23720292
53. Ding Y-H, Li J, Zhou Y, Rafols JA, Clark JC, Ding Y. Cerebral angiogenesis and expression of angio-genic factors in aging rats after exercise. Curr Neurovasc Res. 2006 Feb; 3(1):15–23. PMID: 16472122