A biosynthetic route for polysialylating proteins in Escherichia coli

Metabolic Engineering

Volumn 44, Issue , 2017, Pages 293-301

  Keys, Timothy G ^a   Wetter, Michael ^b   Hang, Ivan ^a   Rutschmann, Christoph ^b   Russo, Simona ^b   Mally, Manuela ^b   Steffen, Michael ^b   Zuppiger, Matthias ^b   Müller, Fabian ^b   Schneider, Jörg ^b   Faridmoayer, Amirreza ^b   Lin, Chia wei ^a   Aebi, Markus ^a  

^a ETH ZURICH   (Switzerland)

^b LimmaTech Biologics   (Switzerland)

Author keywords

DARPin; Glycoengineering; N glycosyltransferase; Polysialic acid; Stealth polymer

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CYTOLOGY; ESCHERICHIA COLI;

BIOSYNTHETIC PATHWAY; CAPSULAR POLYSACCHARIDES; DARPIN; GLYCOENGINEERING; GLYCOSYL TRANSFERASE; GREEN FLUORESCENT PROTEIN; POLYSIALIC ACID; POST-TRANSLATIONAL MODIFICATIONS;

RECOMBINANT PROTEINS;

AMPICILLIN; CHLORAMPHENICOL; ESCHERICHIA COLI PROTEIN; GLYCOSYLTRANSFERASE; GREEN FLUORESCENT PROTEIN; IMIDAZOLE; LIPOOLIGOSACCHARIDE; LIPOPOLYSACCHARIDE; POLYSACCHARIDE; POLYSIALIC ACID; RECOMBINANT PROTEIN; SPECTINOMYCIN; TRIMETHOPRIM; SIALIC ACID DERIVATIVE;

ADDITION REACTION; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; CYTOPLASM; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN TARGETING; SIALYLATION; GENETICS; GLYCOSYLATION; METABOLISM; TRANSLATIONAL PROTEIN MODIFICATION;

ESCHERICHIA COLI; GLYCOSYLATION; GREEN FLUORESCENT PROTEINS; PROTEIN MODIFICATION, TRANSLATIONAL; RECOMBINANT PROTEINS; SIALIC ACIDS;

EID: 85033599068     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2017.10.012     Document Type: Article

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