Production of the bioactive isoflavone O-desmethylangolensin by Enterococcus faecium INIA P553 with high efficiency

Journal of Functional Foods

Volumn 40, Issue , 2018, Pages 180-186

  Gaya, Pilar ^a   Peirotén, Ángela ^a   Álvarez, Inmaculada ^b   Medina, Margarita ^a   Landete, José Mª ^a  

^a INIA   (Spain)

^b INSTITUTE OF FOOD SCIENCE   (Spain)

Author keywords

Enterococcus faecium; Food; Isoflavones; O desmethylangolensin; Probiotic

Indexed keywords

EID: 85033448335     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2017.11.008     Document Type: Article

References (27)

1. Atkinson, C., Frankenfeld, C.L., Lampe, J.W., Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health. Experimental Biology and Medicine 230:3 (2005), 155–170.
2. Barbosa, J., Borges, S., Teixeia, P., Selection of potential probiotic Enterococcus faecium isolated from Portuguese fermented food. International Journal of Food Microbiology 191 (2014), 144–148.
3. Choi, E.J., Kim, G.H., O-desmethylangolensin inhibits the proliferation of human breast cancer MCF-7 cells by inducing apoptosis and promoting cell cycle arrest. Oncology Letters 6:6 (2013), 1784–1788, 10.3892/ol.2013.1601.
4. Choi, E.J., Lee, J.-I., Kim, G.-H., Anticancer effects of O-desmethylangolensin are mediated through cell cycle arrest at the G2/M phase and mitochondrial-dependent apoptosis in Hep3B human hepatocellular carcinoma cells. International Journal of Molecular Medicine 31 (2013), 726–730.
5. Coldham, N.G., Howells, L.C., Santi, A., Montesissa, C., Langlais, C., King, L.J., Sauer, M.J., Biotransformation of genistein in the rat: Elucidation of metabolite structure by product ion mass fragmentology. The Journal of Steroid Biochemistry and Molecular Biology 70 (1999), 169–184.
6. Delmonte, P., Perry, J., Rader, J.I., Determination of isoflavones in dietary supplements containing soy, Red Clover and kudzu: Extraction followed by basic or acid hydrolysis. Journal of Chromatography A 1107:1–2 (2006), 59–69.
7. Dixon, R.A., Phytoestrogens. Annual Review of Plant Biology 55 (2004), 225–261.
8. EFSA Panel on additives and products or substances used in animal Feed (FEEDAP), Guidance on the assessment of bacterial susceptibility to antimicrobials of human and veterinary importance. EFSA Journal, 10(6), 2012, 2740, 10.2903/j.efsa.2012.2740.
9. Frankenfeld, C.L., O-Desmethylangolensin: The importance of equol's lesser known cousin to human health. Advances in Nutrition 2 (2011), 317–324.
10. Frankenfeld, C.L., Atkinson, C., Thomas, W.K., González, A., High concordance of daidzein-metabolizing phenotypes in individuals measured 1 to 3 years apart. British Journal of Nutrition 94 (2005), 873–876.
11. Franz, C.M.A.P., Huch, M., Abriouel, H., Holzapfel, W., Gálvez, A., Enterococci as probiotics and their implication in food safety. International Journal of Food Microbiology 151 (2011), 125–140.
12. Gaya, P., Arqués, J.L., Medina, M., Álvarez, I., Landete, J.M., A new HPLC-PAD/HPLC-ESI-MS method for the analysis of phytoestrogens produced by bacterial metabolism. Food Analytical Methods 9:2 (2016), 537–547, 10.1007/s12161-015-0226-3.
13. Gaya, P., Medina, M., Sánchez-Jiménez, A., Landete, J.M., Phytoestrogen metabolism by adult human gut microbiota. Molecules, 21(8), 2016, 10.3390/molecules21081034.
14. Giraffa, G., Functionality of enterococci in dairy products. International Journal of Food Microbiology 88 (2003), 215–222.
15. Heinonen, S.-T., Wähälä, K., Adlercreutz, H., Identification of urinary metabolites of the red clover isoflavones formononetin and biochanin A in human subjects. Journal of Agricultural and Food Chemistry 52:22 (2004), 6802–6809.
16. Hodgson, J.M., Croft, K.D., Puddey, I.B., Mori, T.A., Beilin, L.J., Soybean isoflavonoids and their metabolic products inhibit in vitro lipoprotein oxidation in serum. Journal of Nutritional Biochemistry 7 (1996), 664–669.
17. Hur, H.-G., Beger, R.D., Heinze, T.M., Lay, J.O., Freeman, J.P., Dore, J., Rafii, F., Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein. Archives of Microbiology 178 (2002), 8–12.
18. Jin, S., Zhang, Q.Y., Kang, X.M., Wang, J.X., Zhao, W.H., Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway. Annals of Oncology 21:2 (2009), 263–268, 10.1093/annonc/mdp499.
19. Khaodhiar, L., Ricciotti, H.A., Li, L., Pan, W., Schickel, M., Zhou, J., Blackburn, G.L., Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women. Menopause 15:1 (2008), 125–132.
20. Klein, G., Taxonomy, ecology and antibiotic resistance of enterococci from food and the gastro-intestinal tract. International Journal of Food Microbiology 88 (2003), 123–131.
21. Landete, J.M., Arqués, J.L., Medina, M., Gaya, P., de las Rivas, B., Muñoz, R., Bioactivation of phytoestrogens: Intestinal bacteria and health. Critical Review in Food Science and Nutrition 56:11 (2016), 1826–1843.
22. Li, M., Li, H., Zhang, X.L., Chen, B.-H., Hao, Q.H., Wang, S.Y., Enhanced biosynthesis of O-desmethylangolensin from daidzein by a novel oxygen-tolerant cock intestinal bacterium in the presence of atmospheric oxygen. Journal of Applied Microbiology 118 (2015), 619–628.
23. Martín, R., Langa, S., Reviriego, C., Jiménez, E., Marín, M.L., Xaus, J., Rodríguez, J.M., Human milk is a source of lactic acid bacteria for the infant gut. Journal of Pediatrics 143 (2003), 754–758.
24. Moreno, M.R.F., Sarantinopoulos, P., Tsakalidou, E., De Vuys, L., The role and application of enterococci in food and health. International Journal of Food Microbiology 106 (2006), 1–24.
25. Schoefer, L., Mohan, R., Braune, A., Birringer, M., Blaut, M., Anaerobic C-ring cleavage of genistein and daidzein by Eubacterium ramulus. FEMS Microbiology Letters 208 (2002), 197–202.
26. Setchell, K.D., Brown, N.M., Desai, P., Zimmer-Nechemias, L., Wolfe, B.E., Brashear, W.T., Heubi, J.E., Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements. The Journal of Nutrition 131:4S (2001), 1362S–1375S.
27. Yokoyama, S.-I., Niwa, T., Osawa, T., Suzuki, T., Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces. Archives of Microbiology 192 (2010), 15–22.