Nanomechanical testing of drug activities at the cellular level: Case study for endothelium-targeted drugs

Pharmacological Reports

Volumn 69, Issue 6, 2017, Pages 1165-1172

  Kolodziejczyk, Agnieszka M ^a,b   Targosz Korecka, Marta ^a   Szymonski, Marek ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b Bionanopark Ltd   (Poland)

Author keywords

Endothelium cell; Endothelium targeted drugs; Force spectroscopy; Pyridine derivatives; Simvastatin

Indexed keywords

1 METHYLPYRIDINIUM CHLORIDE; 1,4 DIMETHYLPYRIDINE CHLORIDE; F ACTIN; METHYL GROUP; PYRIDINE DERIVATIVE; SIMVASTATIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 1-METHYLPYRIDINIUM; ACTIN; ANTIINFLAMMATORY AGENT; PYRIDINIUM DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL LABELING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG TARGETING; ELASTICITY; FORCE SPECTROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; MOLECULAR MECHANICS; SPECTROSCOPY; ATOMIC FORCE MICROSCOPY; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENDOTHELIUM CELL; INFLAMMATION; METABOLISM; MICROVASCULATURE; PATHOLOGY; PROSPECTIVE STUDY; VASCULAR ENDOTHELIUM;

ACTINS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; ELASTICITY; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; INFLAMMATION; MICROSCOPY, ATOMIC FORCE; MICROVESSELS; PROSPECTIVE STUDIES; PYRIDINIUM COMPOUNDS; SIMVASTATIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85033437131     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/j.pharep.2017.06.007     Document Type: Article

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