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Volumn 74, Issue 2, 2018, Pages 201-208

Antidepressants and suicidal behaviour in late life: a prospective population-based study of use patterns in new users aged 75 and above

Author keywords

Aged; Antidepressants; Cohort study; Pharmacoepidemiology; Suicide

Indexed keywords

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; CITALOPRAM; DULOXETINE; ESCITALOPRAM; HYPNOTIC AGENT; MIRTAZAPINE; MOOD STABILIZER; NEUROLEPTIC AGENT; NOOTROPIC AGENT; NORADRENALIN UPTAKE INHIBITOR; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 85032807892     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-017-2360-x     Document Type: Article
Times cited : (11)

References (47)
  • 1
    • 85040350846 scopus 로고    scopus 로고
    • [In Swedish] Accessed 17 Aug 2017
    • Statistics Sweden (2016) Statistics on Causes of Death 2015 [In Swedish]. http://www.socialstyrelsen.se/publikationer2016/2016-8-4. Accessed 17 Aug 2017
    • (2016) Statistics on Causes of Death , pp. 2015
    • Sweden, S.1
  • 2
    • 84867386138 scopus 로고    scopus 로고
    • Global suicide mortality rates—a light at the end of the tunnel?
    • PID: 22935272
    • Bertolote JM, De Leo D (2012) Global suicide mortality rates—a light at the end of the tunnel? Crisis 33(5):249–253
    • (2012) Crisis , vol.33 , Issue.5 , pp. 249-253
    • Bertolote, J.M.1    De Leo, D.2
  • 3
    • 0036197120 scopus 로고    scopus 로고
    • A case control study of suicide and attempted suicide in older adults
    • PID: 11931007
    • Beautrais AL (2002) A case control study of suicide and attempted suicide in older adults. Suicide Life Threat Behav 32(1):1–9
    • (2002) Suicide Life Threat Behav , vol.32 , Issue.1 , pp. 1-9
    • Beautrais, A.L.1
  • 4
    • 61449149600 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors and risk of suicide: a systematic review of observational studies
    • Barbui C, Esposito E, Cipriani A (2009) Selective serotonin reuptake inhibitors and risk of suicide: a systematic review of observational studies. Can Med Assoc J 180(3):291–297
    • (2009) Can Med Assoc J , vol.180 , Issue.3 , pp. 291-297
    • Barbui, C.1    Esposito, E.2    Cipriani, A.3
  • 5
    • 13244288648 scopus 로고    scopus 로고
    • The relationship between antidepressant medication use and rate of suicide
    • COI: 1:CAS:528:DC%2BD2MXhvFGmsLg%3D, PID: 15699293
    • Gibbons RD, Hur K, Bhaumik DK, Mann JJ (2005) The relationship between antidepressant medication use and rate of suicide. Arch Gen Psychiatry 62(2):165–172
    • (2005) Arch Gen Psychiatry , vol.62 , Issue.2 , pp. 165-172
    • Gibbons, R.D.1    Hur, K.2    Bhaumik, D.K.3    Mann, J.J.4
  • 6
    • 0034112529 scopus 로고    scopus 로고
    • Antidepressants in the elderly: challenges for study design and their interpretation
    • COI: 1:CAS:528:DC%2BD3cXks1Snsb4%3D, PID: 10848717
    • Parikh C (2000) Antidepressants in the elderly: challenges for study design and their interpretation. Br J Clin Pharmacol 49(6):539–547
    • (2000) Br J Clin Pharmacol , vol.49 , Issue.6 , pp. 539-547
    • Parikh, C.1
  • 7
    • 0032710433 scopus 로고    scopus 로고
    • Antidepressant drug interactions in the elderly: understanding the P-450 system is half the battle in reducing risks
    • COI: 1:STN:280:DC%2BD3c%2Fktleitg%3D%3D, PID: 10576014
    • Cadieux RJ (1999) Antidepressant drug interactions in the elderly: understanding the P-450 system is half the battle in reducing risks. Postgrad Med 106(6):231–249
    • (1999) Postgrad Med , vol.106 , Issue.6 , pp. 231-249
    • Cadieux, R.J.1
  • 8
    • 0029786161 scopus 로고    scopus 로고
    • Treatment outcome in recurrent major depression: a post hoc comparison of elderly (“young old”) and midlife patients
    • PID: 8831436
    • Reynolds CF III, Frank E, Kupfer DJ, Thase ME (1996) Treatment outcome in recurrent major depression: a post hoc comparison of elderly (“young old”) and midlife patients. Am J Psychiatry 153(10):1288
    • (1996) Am J Psychiatry , vol.153 , Issue.10 , pp. 1288
    • Reynolds, C.F.1    Frank, E.2    Kupfer, D.J.3    Thase, M.E.4
  • 10
    • 0036669286 scopus 로고    scopus 로고
    • Risk factors for suicide in later life
    • PID: 12182926
    • Conwell Y, Duberstein PR, Caine ED (2002) Risk factors for suicide in later life. Biol Psychiatry 52(3):193–204
    • (2002) Biol Psychiatry , vol.52 , Issue.3 , pp. 193-204
    • Conwell, Y.1    Duberstein, P.R.2    Caine, E.D.3
  • 11
    • 42549111771 scopus 로고    scopus 로고
    • Increased use of antidepressants and decreasing suicide rates: a population-based study using Danish register data
    • COI: 1:STN:280:DC%2BD1c3ltlClsg%3D%3D, PID: 18413459
    • Erlangsen A, Canudas-Romo V, Conwell Y (2008) Increased use of antidepressants and decreasing suicide rates: a population-based study using Danish register data. J Epidemiol Community Health 62(5):448–454
    • (2008) J Epidemiol Community Health , vol.62 , Issue.5 , pp. 448-454
    • Erlangsen, A.1    Canudas-Romo, V.2    Conwell, Y.3
  • 12
    • 80052913150 scopus 로고    scopus 로고
    • Antidepressant use and risk of adverse outcomes in older people: population based cohort study
    • PID: 21810886
    • Coupland C, Dhiman P, Morriss R, Arthur A, Barton G, Hippisley-Cox J (2011) Antidepressant use and risk of adverse outcomes in older people: population based cohort study. BMJ 343:d4551
    • (2011) BMJ , vol.343 , pp. d4551
    • Coupland, C.1    Dhiman, P.2    Morriss, R.3    Arthur, A.4    Barton, G.5    Hippisley-Cox, J.6
  • 14
    • 8444225846 scopus 로고    scopus 로고
    • Psychotropic prescriptions and elderly suicide rates
    • PID: 15296248
    • Lodhi LM, Shah A (2004) Psychotropic prescriptions and elderly suicide rates. Med Sci Law 44(3):236–244
    • (2004) Med Sci Law , vol.44 , Issue.3 , pp. 236-244
    • Lodhi, L.M.1    Shah, A.2
  • 15
    • 67650708888 scopus 로고    scopus 로고
    • Are sedatives and hypnotics associated with increased suicide risk of suicide in the elderly?
    • PID: 19497093
    • Carlsten A, Waern M (2009) Are sedatives and hypnotics associated with increased suicide risk of suicide in the elderly? BMC Geriatr 9:20
    • (2009) BMC Geriatr , vol.9 , pp. 20
    • Carlsten, A.1    Waern, M.2
  • 16
    • 70449521194 scopus 로고    scopus 로고
    • The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research
    • PID: 19504049
    • Ludvigsson JF, Otterblad-Olausson P, Pettersson BU, Ekbom A (2009) The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research. Eur J Epidemiol 24(11):659–667
    • (2009) Eur J Epidemiol , vol.24 , Issue.11 , pp. 659-667
    • Ludvigsson, J.F.1    Otterblad-Olausson, P.2    Pettersson, B.U.3    Ekbom, A.4
  • 17
    • 0142157169 scopus 로고    scopus 로고
    • Evaluating medication effects outside of clinical trials: new-user designs
    • PID: 14585769
    • Ray WA (2003) Evaluating medication effects outside of clinical trials: new-user designs. Am J Epidemiol 158(9):915–920
    • (2003) Am J Epidemiol , vol.158 , Issue.9 , pp. 915-920
    • Ray, W.A.1
  • 19
    • 85035204918 scopus 로고    scopus 로고
    • Accessed 17 Aug 2017, Swedish National Board of Health and Welfare
    • Swedish National Board of Health and Welfare (2016) The National Patient Register. http://www.socialstyrelsen.se/register/halsodataregister/patientregistret/inenglish. Accessed 17 Aug 2017
    • (2016) The National Patient Register
  • 20
    • 79955419071 scopus 로고    scopus 로고
    • Guidelines for ATC classification and DDD assignment 2013
    • WHO Collaborating Centre for Drug Statistics Methodology
    • WHO Collaborating Centre for Drug Statistics Methodology (2012) Guidelines for ATC classification and DDD assignment 2013. Oslo
    • (2012) Oslo
  • 21
    • 68849111657 scopus 로고    scopus 로고
    • To what extent does the indicator “concurrent use of three or more psychotropic drugs” capture use of potentially inappropriate psychotropics among the elderly?
    • PID: 19219427
    • Lesén E, Petzold M, Andersson K, Carlsten A (2009) To what extent does the indicator “concurrent use of three or more psychotropic drugs” capture use of potentially inappropriate psychotropics among the elderly? Eur J Clin Pharmacol 65(6):635–642
    • (2009) Eur J Clin Pharmacol , vol.65 , Issue.6 , pp. 635-642
    • Lesén, E.1    Petzold, M.2    Andersson, K.3    Carlsten, A.4
  • 23
    • 84865527258 scopus 로고    scopus 로고
    • Heartache and heartbreak—the link between depression and cardiovascular disease
    • COI: 1:CAS:528:DC%2BC38Xht1GjtrvP, PID: 22733213
    • Nemeroff CB, Goldschmidt-Clermont PJ (2012) Heartache and heartbreak—the link between depression and cardiovascular disease. Nat Rev Cardiol 9(9):526–539
    • (2012) Nat Rev Cardiol , vol.9 , Issue.9 , pp. 526-539
    • Nemeroff, C.B.1    Goldschmidt-Clermont, P.J.2
  • 24
    • 84942549524 scopus 로고    scopus 로고
    • Physical diseases as predictors of suicide in older adults: a nationwide, register-based cohort study
    • PID: 25835959
    • Erlangsen A, Stenager E, Conwell Y (2015) Physical diseases as predictors of suicide in older adults: a nationwide, register-based cohort study. Soc Psychiatry Psychiatr Epidemiol 50(9):1427–1439
    • (2015) Soc Psychiatry Psychiatr Epidemiol , vol.50 , Issue.9 , pp. 1427-1439
    • Erlangsen, A.1    Stenager, E.2    Conwell, Y.3
  • 27
    • 1542532754 scopus 로고    scopus 로고
    • A proportional hazards model for the subdistribution of a competing risk
    • Fine JP, Gray RJ (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94(446):496–509
    • (1999) J Am Stat Assoc , vol.94 , Issue.446 , pp. 496-509
    • Fine, J.P.1    Gray, R.J.2
  • 28
    • 0037132876 scopus 로고    scopus 로고
    • Bias and causal associations in observational research
    • PID: 11812579
    • Grimes DA, Schulz KF (2002) Bias and causal associations in observational research. Lancet 359(9302):248–252
    • (2002) Lancet , vol.359 , Issue.9302 , pp. 248-252
    • Grimes, D.A.1    Schulz, K.F.2
  • 31
    • 74349105941 scopus 로고    scopus 로고
    • Attempted suicide in the elderly: characteristics of suicide attempters 70 years and older and a general population comparison group
    • PID: 20094019
    • Wiktorsson S, Runeson B, Skoog I, Östling S, Waern M (2010) Attempted suicide in the elderly: characteristics of suicide attempters 70 years and older and a general population comparison group. Am J Geriatr Psychiatry 18(1):57–67
    • (2010) Am J Geriatr Psychiatry , vol.18 , Issue.1 , pp. 57-67
    • Wiktorsson, S.1    Runeson, B.2    Skoog, I.3    Östling, S.4    Waern, M.5
  • 32
    • 84874984153 scopus 로고    scopus 로고
    • Suicidal feelings in the twilight of life: a cross-sectional population-based study of 97-year-olds
    • PID: 23377994
    • Fässberg MM, Östling S, Börjesson-Hanson A, Skoog I, Wærn M (2013) Suicidal feelings in the twilight of life: a cross-sectional population-based study of 97-year-olds. BMJ Open 3(2):e002260
    • (2013) BMJ Open , vol.3 , Issue.2
    • Fässberg, M.M.1    Östling, S.2    Börjesson-Hanson, A.3    Skoog, I.4    Wærn, M.5
  • 33
    • 70350780206 scopus 로고    scopus 로고
    • Good research practices for comparative effectiveness research: approaches to mitigate bias and confounding in the design of nonrandomized studies of treatment effects using secondary data sources: the International Society for Pharmacoeconomics and Outcomes Research Good Research Practices for Retrospective Database Analysis Task Force Report—Part II
    • PID: 19744292
    • Cox E, Martin BC, Van Staa T, Garbe E, Siebert U, Johnson ML (2009) Good research practices for comparative effectiveness research: approaches to mitigate bias and confounding in the design of nonrandomized studies of treatment effects using secondary data sources: the International Society for Pharmacoeconomics and Outcomes Research Good Research Practices for Retrospective Database Analysis Task Force Report—Part II. Value Health 12(8):1053–1061
    • (2009) Value Health , vol.12 , Issue.8 , pp. 1053-1061
    • Cox, E.1    Martin, B.C.2    Van Staa, T.3    Garbe, E.4    Siebert, U.5    Johnson, M.L.6
  • 34
    • 0038294698 scopus 로고    scopus 로고
    • Alcohol dependence and misuse in elderly suicides
    • PID: 12711660
    • Waern M (2003) Alcohol dependence and misuse in elderly suicides. Alcohol Alcohol 38(3):249–254
    • (2003) Alcohol Alcohol , vol.38 , Issue.3 , pp. 249-254
    • Waern, M.1
  • 35
    • 0030434199 scopus 로고    scopus 로고
    • Comorbid depression and anxiety spectrum disorders
    • PID: 9166648
    • Gorman JM (1996) Comorbid depression and anxiety spectrum disorders. Depress Anxiety 4(4):160–168
    • (1996) Depress Anxiety , vol.4 , Issue.4 , pp. 160-168
    • Gorman, J.M.1
  • 36
    • 0031007193 scopus 로고    scopus 로고
    • Course of depression in patients with comorbid anxiety disorders
    • COI: 1:STN:280:DyaK2szjtVegtA%3D%3D, PID: 9186795
    • Sherbourne CD, Wells KB (1997) Course of depression in patients with comorbid anxiety disorders. J Affect Disord 43(3):245–250
    • (1997) J Affect Disord , vol.43 , Issue.3 , pp. 245-250
    • Sherbourne, C.D.1    Wells, K.B.2
  • 37
    • 84866658177 scopus 로고    scopus 로고
    • Anxiety symptoms and suicidal feelings in a population sample of 70-year-olds without dementia
    • PID: 22647285
    • Jonson M, Skoog I, Marlow T, Fässberg MM, Waern M (2012) Anxiety symptoms and suicidal feelings in a population sample of 70-year-olds without dementia. Int Psychogeriatr 24(11):1865–1871
    • (2012) Int Psychogeriatr , vol.24 , Issue.11 , pp. 1865-1871
    • Jonson, M.1    Skoog, I.2    Marlow, T.3    Fässberg, M.M.4    Waern, M.5
  • 38
    • 84896740322 scopus 로고    scopus 로고
    • Secular changes in at-risk drinking in Sweden: birth cohort comparisons in 75-year-old men and women 1976–2006
    • PID: 24067499
    • Waern M, Marlow T, Morin J, Östling S, Skoog I (2013) Secular changes in at-risk drinking in Sweden: birth cohort comparisons in 75-year-old men and women 1976–2006. Age Ageing 43(2):228–234
    • (2013) Age Ageing , vol.43 , Issue.2 , pp. 228-234
    • Waern, M.1    Marlow, T.2    Morin, J.3    Östling, S.4    Skoog, I.5
  • 39
    • 84971516878 scopus 로고    scopus 로고
    • Switching and stopping antidepressants
    • PID: 27346915
    • Keks N, Hope J, Keogh S (2016) Switching and stopping antidepressants. Aust Prescr 39(3):76–83
    • (2016) Aust Prescr , vol.39 , Issue.3 , pp. 76-83
    • Keks, N.1    Hope, J.2    Keogh, S.3
  • 40
    • 77949426913 scopus 로고    scopus 로고
    • Pharmacologic approaches to treatment resistant depression: a re-examination for the modern era
    • COI: 1:CAS:528:DC%2BC3cXivFWmtLg%3D, PID: 20151847
    • Philip NS, Carpenter LL, Tyrka AR, Price LH (2010) Pharmacologic approaches to treatment resistant depression: a re-examination for the modern era. Expert Opin Pharmacother 11(5):709–722
    • (2010) Expert Opin Pharmacother , vol.11 , Issue.5 , pp. 709-722
    • Philip, N.S.1    Carpenter, L.L.2    Tyrka, A.R.3    Price, L.H.4
  • 41
    • 0033963172 scopus 로고    scopus 로고
    • Managing antipsychotic-induced acute and chronic akathisia
    • COI: 1:STN:280:DC%2BD3c7ht1GjsQ%3D%3D, PID: 10647977
    • Miller CH, Fleischhacker WW (2000) Managing antipsychotic-induced acute and chronic akathisia. Drug Saf 22(1):73–81
    • (2000) Drug Saf , vol.22 , Issue.1 , pp. 73-81
    • Miller, C.H.1    Fleischhacker, W.W.2
  • 42
    • 76749149554 scopus 로고    scopus 로고
    • Acute antipsychotic-induced akathisia revisited
    • PID: 20118449
    • Poyurovsky M (2010) Acute antipsychotic-induced akathisia revisited. Br J Psychiatry 196(2):89–91
    • (2010) Br J Psychiatry , vol.196 , Issue.2 , pp. 89-91
    • Poyurovsky, M.1
  • 44
    • 44649096951 scopus 로고    scopus 로고
    • Hospital-diagnosed dementia and suicide: a longitudinal study using prospective, nationwide register data
    • PID: 18310552
    • Erlangsen A, Zarit SH, Conwell Y (2008) Hospital-diagnosed dementia and suicide: a longitudinal study using prospective, nationwide register data. Am J Geriatr Psychiatry 16(3):220–228
    • (2008) Am J Geriatr Psychiatry , vol.16 , Issue.3 , pp. 220-228
    • Erlangsen, A.1    Zarit, S.H.2    Conwell, Y.3
  • 45
    • 70349982864 scopus 로고    scopus 로고
    • Early discontinuation of antidepressant treatment and suicide risk among persons aged 50 and over: a population-based register study
    • COI: 1:CAS:528:DC%2BD1MXht1Ogt7vN, PID: 19376594
    • Erlangsen A, Agerbo E, Hawton K, Conwell Y (2009) Early discontinuation of antidepressant treatment and suicide risk among persons aged 50 and over: a population-based register study. J Affect Disord 119(1):194–199
    • (2009) J Affect Disord , vol.119 , Issue.1 , pp. 194-199
    • Erlangsen, A.1    Agerbo, E.2    Hawton, K.3    Conwell, Y.4
  • 46
    • 34547858080 scopus 로고    scopus 로고
    • Increased use of antidepressants at the end of life: population-based study among people aged 65 years and above
    • PID: 17537746
    • Hansen DG, Rosholm J-U, Gichangi A, Vach W (2007) Increased use of antidepressants at the end of life: population-based study among people aged 65 years and above. Age Ageing 36(4):449–454
    • (2007) Age Ageing , vol.36 , Issue.4 , pp. 449-454
    • Hansen, D.G.1    Rosholm, J.-U.2    Gichangi, A.3    Vach, W.4
  • 47
    • 85040328416 scopus 로고    scopus 로고
    • Accessed 17 Oct 2017, National Board of Health and Welfare
    • National Board of Health and Welfare (2016). Statistical database for causes of death [In Swedish]. http://www.socialstyrelsen.se/statistik/statistikdatabas/dodsorsaker. Accessed 17 Oct 2017
    • (2016) Statistical database for causes of death [In Swedish


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