Tumor necrosis factor-alpha levels in blood cord is directly correlated with the body weight of mothers

Obesity Science and Practice

Volumn 2, Issue 2, 2016, Pages 210-214

  de Toledo Baldi, E ^a   Dias Bobbo V C ^a   Melo Lima, M H ^a   Velloso, L A ^a   Pereira de Araujo, E ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Inflammation; obesity; offspring; tumour necrosis factor alpha

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TUMOR NECROSIS FACTOR;

ADULT; ARTICLE; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL OBESITY; PREDICTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN LOCALIZATION; UMBILICAL CORD BLOOD;

EID: 85032618243     PISSN: None     EISSN: 20552238     Source Type: Journal    
DOI: 10.1002/osp4.47     Document Type: Article

References (21)

1. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993; 259: 87–91.
2. Hotamisligil GS: Mechanisms of TNF-alpha-induced insulin resistance. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1999;107:119–125
3. Velloso LA, Folli F, Saad MJ. TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation. Endocr Rev 2015; 36: 245–271.
4. Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860–867.
5. Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006; 444: 840–846.
6. Jager J, Gremeaux T, Cormont M, Le Marchand-Brustel Y, Tanti JF. Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression. Endocrinology 2007; 148: 241–251.
7. Alessi MC, Bastelica D, Morange P, et al. Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. Diabetes 2000; 49: 1374–1380.
8. Koska J, Stefan N, Dubois S, et al. mRNA concentrations of MIF in subcutaneous abdominal adipose cells are associated with adipocyte size and insulin action. International journal of obesity 2009; 33: 842–850.
9. Ghanim H, Aljada A, Daoud N, Deopurkar R, Chaudhuri A, Dandona P. Role of inflammatory mediators in the suppression of insulin receptor phosphorylation in circulating mononuclear cells of obese subjects. Diabetologia 2007; 50: 278–285.
10. Osborn O, Olefsky JM. The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 2012; 18: 363–374.
11. Desai M, Jellyman JK, Ross MG. Epigenomics, gestational programming and risk of metabolic syndrome. International journal of obesity 2015; 39: 633–641.
12. Howie GJ, Sloboda DM, Kamal T, Vickers MH. Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet. J Physiol 2009; 587: 905–915.
13. Dunn GA, Bale TL. Maternal high-fat diet effects on third-generation female body size via the paternal lineage. Endocrinology 2011; 152: 2228–2236.
14. White CL, Purpera MN, Morrison CD. Maternal obesity is necessary for programming effect of high-fat diet on offspring. American journal of physiology Regulatory, integrative and comparative physiology 2009; 296: R1464–1472.
15. Kim DW, Young SL, Grattan DR, Jasoni CL. Obesity during pregnancy disrupts placental morphology, cell proliferation, and inflammation in a sex-specific manner across gestation in the mouse. Biology of reproduction 2014; 90: 130.
16. Ingvorsen C, Thysen AH, Fernandez-Twinn D, et al. Effects of pregnancy on obesity-induced inflammation in a mouse model of fetal programming. International journal of obesity 2014; 38: 1282–1289.
17. Atalah E, Castillo C, Castro R. Aldea A: [Proposal of a new standard for the nutritional assessment of pregnant women]. Rev Med Chil 1997; 125: 1429–1436.
18. Varastehpour A, Radaelli T, Minium J, et al. Activation of phospholipase A2 is associated with generation of placental lipid signals and fetal obesity. The Journal of clinical endocrinology and metabolism 2006; 91: 248–255.
19. Challier JC, Basu S, Bintein T, et al. Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta. Placenta 2008; 29: 274–281.
20. Aye IL, Lager S, Ramirez VI, et al. Increasing maternal body mass index is associated with systemic inflammation in the mother and the activation of distinct placental inflammatory pathways. Biology of reproduction 2014; 90: 129.
21. Barker DJ. The developmental origins of adult disease. Journal of the American College of Nutrition 2004; 23: 588S–595S.