Prebiotics for the prevention of allergies: A systematic review and meta-analysis of randomized controlled trials

Clinical and Experimental Allergy

Volumn 47, Issue 11, 2017, Pages 1468-1477

  Cuello Garcia, C ^a   Fiocchi, A ^b   Pawankar, R ^c   Yepes Nunez J J ^a,d   Morgano, G P ^a   Zhang, Y ^a   Agarwal, A ^e   Gandhi, S ^e   Terracciano, L ^f   Schunemann H J ^a   Brozek, J L ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^c NIPPON MEDICAL SCHOOL   (Japan)

^d UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF MILAN   (Italy)

Author keywords

allergy; prebiotics; prevention; systematic review

Indexed keywords

PREBIOTIC AGENT;

ALLERGY; ARTICLE; ASTHMA; BODY WEIGHT; DIET SUPPLEMENTATION; DRUG EFFECT; ECZEMA; FOOD ALLERGY; GROWTH RATE; HUMAN; META ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTEMATIC REVIEW; WHEEZING; BREAST FEEDING; DIETARY SUPPLEMENT; FEMALE; FOLLOW UP; HYPERSENSITIVITY; IMMUNOLOGY; INFANT; ODDS RATIO; PREGNANCY; PUBLISHING;

BREAST FEEDING; DIETARY SUPPLEMENTS; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERSENSITIVITY; INFANT; ODDS RATIO; PREBIOTICS; PREGNANCY; PUBLICATION BIAS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 85032285202     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.13042     Document Type: Article

References (41)

1. Warner JO, Kaliner MA, Crisci CD, et al. Allergy practice worldwide: a report by the World Allergy Organization Specialty and Training Council. Int Arch Allergy Immunol. 2006;139:166-174.
2. Arshad SH, Kurukulaaratchy RJ, Fenn M, Matthews S. Early life risk factors for current wheeze, asthma, and bronchial hyperresponsiveness at 10 years of age. Chest. 2005;127:502-508.
3. Ait-Khaled N, Pearce N, Anderson HR, et al. Global map of the prevalence of symptoms of rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three. Allergy. 2009;64:123-148.
4. Lai CK, Beasley R, Crane J, et al. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2009;64:476-483.
5. Odhiambo JA, Williams HC, Clayton TO, Robertson CF, Asher MI, Group IPTS. Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three. J Allergy Clin Immunol. 2009;124:1251-1258 e23.
6. Lodge CJ, Allen KJ, Lowe AJ, Dharmage SC. Overview of evidence in prevention and aetiology of food allergy: a review of systematic reviews. Int J Environ Res Public Health. 2013;10:5781-5806.
7. Rastall RA, Gibson GR. Recent developments in prebiotics to selectively impact beneficial microbes and promote intestinal health. Curr Opin Biotechnol. 2015;32:42-46.
8. Okada H, Kuhn C, Feillet H, Bach JF. The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update. Clin Exp Immunol. 2010;160:1-9.
9. Osborn DA, Sinn JK. Prebiotics in infants for prevention of allergy. Cochrane Database Syst Rev. 2013;3:CD006474.
10. Cuello-Garcia CA, Brozek JL, Fiocchi A, et al. Probiotics for the prevention of allergy: a systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol. 2015;136:952-961.
11. Perkin MR, Logan K, Tseng A, et al. Randomized trial of introduction of allergenic foods in breast-fed infants. N Engl J Med. 2016;374:1733-1743.
12. Cuello-Garcia CA, Fiocchi A, Pawankar R, et al. World allergy organization-mcmaster university guidelines for allergic disease prevention (GLAD-P): prebiotics. World Allergy Organ J. 2016;9:10.
13. Yepes-Nunez JJ, Fiocchi A, Pawankar R, et al. World allergy organization-mcmaster university guidelines for allergic disease prevention (GLAD-P): vitamin D. World Allergy Organ J. 2016;9:17.
14. Higgins J, Green S. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. London: The Cochrane Collaboration; 2011.
15. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-560.
16. Guyatt GH, Oxman AD, Kunz R, et al. GRADE guidelines: 2. Framing the question and deciding on important outcomes. J Clin Epidemiol. 2011;64:395-400.
17. Bozensky J, Hill M, Zelenka R, Skyba T. Prebiotics do not influence the severity of atopic dermatitis in infants: a randomised controlled trial. PLoS One. 2015;10:e0142897.
18. Moro G, Arslanoglu S, Stahl B, Jelinek J, Wahn U, Boehm G. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age. Arch Dis Child. 2006;91:814-819.
19. Arslanoglu S, Moro GE, Boehm G, Wienz F, Stahl B, Bertino E. Early neutral prebiotic oligosaccharide supplementation reduces the incidence of some allergic manifestations in the first 5 years of life. J Biol Regul Homeost Agents. 2012;26:49-59.
20. Arslanoglu S, Moro GE, Schmitt J, Tandoi L, Rizzardi S, Boehm G. Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life. J Nutr. 2008;138:1091-1095.
21. Gruber C, van Stuijvenberg M, Mosca F, et al. Reduced occurrence of early atopic dermatitis because of immunoactive prebiotics among low-atopy-risk infants. J All Clin Immunol. 2010;126:791-797.
22. Ivakhnenko OS, Nyankovskyy SL. Effect of the specific infant formula mixture of oligosaccharides on local immunity and development of allergic and infectious disease in young children: randomized study. Pediatr Pol. 2013;88:398-404.
23. Lista G, Marangione P, Porcelli F, Menchini M, Castoldi F. Effects of hypoallergenic formula plus oligosaccharides on Faecal pH, Growth pattern and Atopia: A RCT study in newborn infants at risk for allergy, Toronto May 3.8.2007.
24. Ziegler E, Vanderhoof JA, Petschow B, et al. Term infants fed formula supplemented with selected blends of prebiotics grow normally and have soft stools similar to those reported for breast-fed infants. J Pediatr Gastroenterol Nutr. 2007;44:359-364.
25. Boyle R, Tang M-K, Chiang W, et al. Prebiotic-supplemented partially hydrolysed cow's milk formula for the prevention of eczema in high-risk infants: a randomized controlled trial. Allergy. 2016;71:701-710.
26. Sierra C, Bernal MJ, Blasco J, et al. Prebiotic effect during the first year of life in healthy infants fed formula containing GOS as the only prebiotic: a multicentre, randomised, double-blind and placebo-controlled trial. Eur J Nutr. 2015;54:89-99.
27. Ashley C, Johnston WH, Harris CL, Stolz SI, Wampler JL, Berseth CL. Growth and tolerance of infants fed formula supplemented with polydextrose (PDX) and/or galactooligosaccharides (GOS): double-blind, randomized, controlled trial. Nutr J. 2012;11:38.
28. Closa-Monasterolo R, Gispert-Llaurado M, Luque V, et al. Safety and efficacy of inulin and oligofructose supplementation in infant formula: results from a randomized clinical trial. Clin Nutr. 2013;32:918-927.
29. Costalos C, Kapiki A, Apostolou M, Papathoma E. The effect of a prebiotic supplemented formula on growth and stool microbiology of term infants. Early Human Dev. 2008;84:45-49.
30. Moore N, Chao C, Yang LP, Storm H, Oliva-Hemker M, Saavedra JM. Effects of fructo-oligosaccharide-supplemented infant cereal: a double-blind, randomized trial. Br J Nutr. 2003;90:581-587.
31. Piemontese P, Gianni ML, Braegger CP, et al. Tolerance and safety evaluation in a large cohort of healthy infants fed an innovative prebiotic formula: a randomized controlled trial. PLoS One. 2011;6:e28010-e.
32. Scholtens PA, Alliet P, Raes M, et al. Fecal secretory immunoglobulin A is increased in healthy infants who receive a formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides. J Nutr. 2008;138:1141-1147.
33. Wernimont S, Northington R, Kullen MJ, Yao M, Bettler J. Effect of an ?-lactalbumin-enriched infant formula supplemented with oligofructose on fecal microbiota, stool characteristics, and hydration status: a randomized, double-blind, controlled trial. Clin Pediatr. 2015;54:359-370.
34. Bruzzese E, Volpicelli M, Squeglia V, et al. A formula containing galacto- and fructo-oligosaccharides prevents intestinal and extra-intestinal infections: an observational study. Clin Nutr. 2009;28:156-161.
35. Duggan C, Penny ME, Hibberd P, et al. Oligofructose-supplemented infant cereal: 2 randomized, blinded, community-based trials in Peruvian infants. Am J Clin Nutr. 2003;77:937-942.
36. Magne F, Hachelaf W, Suau A, et al. Effects on faecal microbiota of dietary and acidic oligosaccharides in children during partial formula feeding. J Pediatr Gastroenterol Nutr. 2008;46:580-588.
37. Moro G, Minoli I, Mosca M, et al. Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants. J Pediatr Gastroenterol Nutr. 2002;34:291-295.
38. Partty A, Luoto R, Kalliomaki M, Salminen S, Isolauri E. Effects of early prebiotic and probiotic supplementation on development of gut microbiota and fussing and crying in preterm infants: a randomized, double-blind, placebo-controlled trial. J Pediatr. 2013;163:1272-1277.e1-2.
39. Salvini F, Riva E, Salvatici E, et al. A specific prebiotic mixture added to starting infant formula has long-lasting bifidogenic effects. J Nutr. 2011;141:1335-1339.
40. Veereman-Wauters G, Staelens S, Van de Broek H, et al. Physiological and bifidogenic effects of prebiotic supplements in infant formulae. J Pediatr Gastroenterol Nutr. 2011;52:763-771.
41. Ripoll C, Chappuis E, Respondek F, Wagner A, Gottrand F. ScFOS supplemented follow-on formula in healthy infants: impact on vaccine specific faecal secretory IGA response, faecal bifidobacteria, growth and digestive tolerance. Bioactive Carbohydr Diet Fibre. 2015;5:169-178.