A Homer 1 gene variant influences brain structure and function, lithium effects on white matter, and antidepressant response in bipolar disorder: A multimodal genetic imaging study

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 81, Issue , 2018, Pages 88-95

  Benedetti, Francesco ^a   Poletti, Sara ^a,b   Locatelli, Clara ^a   Mazza, Elena ^a   Lorenzi, Cristina ^a   Vitali, Alice ^a   Riberto, Martina ^a   Brioschi, Silvia ^a,b   Vai, Benedetta ^a   Bollettini, Irene ^a   Melloni, Elisa ^a   Aggio, Veronica ^a   Falini, Andrea ^a,b   De Bartolomeis, Andrea ^c   Colombo, Cristina ^a,b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Antidepressant; Bipolar disorder; Brain imaging; Depression; fMRI; Glutamate; Grey matter; Homer; White matter

Indexed keywords

ANTIDEPRESSANT AGENT; LITHIUM SALT; PROTEIN HOMER 1; HOMER SCAFFOLDING PROTEIN; HOMER1 PROTEIN, HUMAN; LITHIUM DERIVATIVE; OXYGEN;

ADULT; ANTERIOR CINGULATE; ARTICLE; BIPOLAR DISORDER; BIPOLAR I DISORDER; BOLD SIGNAL; BRAIN FUNCTION; BRAIN SIZE; CONTROLLED STUDY; FEMALE; FRACTIONAL ANISOTROPY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE; GENETIC VARIABILITY; GENOTYPE; GRAY MATTER; HOMER 1 GENE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MEDIAL PREFRONTAL CORTEX; NEUROIMAGING; PHOTOTHERAPY; SINGLE NUCLEOTIDE POLYMORPHISM; SLEEP DEPRIVATION; VOXEL BASED MORPHOMETRY; WHITE MATTER; BLOOD; BRAIN; BRAIN CIRCULATION; BRAIN MAPPING; CAUCASIAN; DIAGNOSTIC IMAGING; DIFFUSION TENSOR IMAGING; DRUG EFFECT; EMOTION; GENETIC VARIATION; GENETICS; MIDDLE AGED; MULTIMODAL IMAGING; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TREATMENT OUTCOME;

ANTIDEPRESSIVE AGENTS; BIPOLAR DISORDER; BRAIN; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; DEPRESSIVE DISORDER, MAJOR; DIFFUSION TENSOR IMAGING; EMOTIONS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC VARIATION; GRAY MATTER; HOMER SCAFFOLDING PROTEINS; HUMANS; LITHIUM COMPOUNDS; MALE; MIDDLE AGED; MULTIMODAL IMAGING; NEUROPSYCHOLOGICAL TESTS; OXYGEN; PHOTOTHERAPY; SLEEP DEPRIVATION; TREATMENT OUTCOME; WHITE MATTER;

EID: 85032274851     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2017.10.011     Document Type: Article

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