Homer1a drives homeostatic scaling-down of excitatory synapses during sleep

Science

Volumn 355, Issue 6324, 2017, Pages 511-515

  Diering, Graham H ^a   Nirujogi, Raja S ^a   Roth, Richard H ^a   Worley, Paul F ^a   Pandey, Akhilesh ^a   Huganir, Richard L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CHLORPHENIRAMINE MALEATE PLUS PHENYLEPHRINE; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; NORADRENALIN; PROTEIN HOMER 1A; GRM5 PROTEIN, MOUSE; HOMER SCAFFOLDING PROTEIN; HOMER1 PROTEIN, MOUSE; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; METABOTROPIC RECEPTOR 5;

BIOCHEMISTRY; CHEMORECEPTION; GENE EXPRESSION; HOMEOSTASIS; IMAGING METHOD; LEARNING; MEMORY; NERVOUS SYSTEM; NEUROLOGY; PROTEOMICS; RODENT; SLEEP;

ANIMAL EXPERIMENT; AROUSAL; ARTICLE; BIOCHEMISTRY; CELL FRACTIONATION; DEPHOSPHORYLATION; ELECTROCONVULSIVE THERAPY; FIRING RATE; FOREBRAIN; GENE EXPRESSION; IMAGING; MEMORY CONSOLIDATION; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PHENOTYPE; POSTSYNAPTIC DENSITY; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PROTEOMICS; PYRAMIDAL NERVE CELL; SIGNAL NOISE RATIO; SLEEP; SLEEP DEPRIVATION; SYNAPSE; SYNAPTOSOME; WAKEFULNESS; ANIMAL; CELL COUNT; CELL CULTURE; COGNITION; CYTOLOGY; DRUG EFFECTS; GENETICS; HOMEOSTASIS; LEARNING; METABOLISM; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

MUS;

ADENOSINE; ANIMALS; CELL COUNT; CELLS, CULTURED; COGNITION; HOMEOSTASIS; HOMER SCAFFOLDING PROTEINS; LEARNING; MICE; NEURONS; NOREPINEPHRINE; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, METABOTROPIC GLUTAMATE 5; RECEPTORS, METABOTROPIC GLUTAMATE; SLEEP; SYNAPSES; WAKEFULNESS;

EID: 85011325678     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aai8355     Document Type: Article

References (30)

1. S. Diekelmann, J. Born, Nat. Rev. Neurosci. 11, 114-126 (2010).
2. C. G. Vecsey et al., Nature 461, 1122-1125 (2009).
3. V. V. Vyazovskiy, C. Cirelli, M. Pfister-Genskow, U. Faraguna, G. Tononi, Nat. Neurosci. 11, 200-208 (2008).
4. Z. W. Liu, U. Faraguna, C. Cirelli, G. Tononi, X. B. Gao, J. Neurosci. 30, 8671-8675 (2010).
5. G. Tononi, C. Cirelli, Neuron 81, 12-34 (2014).
6. G. G. Turrigiano, Cell 135, 422-435 (2008).
7. A. Goel, H. K. Lee, J. Neurosci. 27, 6692-6700 (2007).
8. K. B. Hengen, A. Torrado Pacheco, J. N. McGregor, S. D. Van Hooser, G. G. Turrigiano, Cell 165, 180-191 (2016).
9. G. H. Diering, A. S. Gustina, R. L. Huganir, Neuron 84, 790-805 (2014).
10. J. H. Hu et al., Neuron 68, 1128-1142 (2010).
11. R. J. O'Brien et al., Neuron 21, 1067-1078 (1998).
12. R. L. Huganir, R. A. Nicoll, Neuron 80, 704-717 (2013).
13. Y. Zhang, R. H. Cudmore, D. T. Lin, D. J. Linden, R. L. Huganir, Nat. Neurosci. 18, 402-407 (2015).
14. J. C. Tu et al., Neuron 21, 717-726 (1998).
15. P. R. Brakeman et al., Nature 386, 284-288 (1997).
16. N. Naidoo et al., PLOS ONE 7, e35174 (2012).
17. A. Ahnaou, X. Langlois, T. Steckler, J. M. Bartolome-Nebreda, W. H. Drinkenburg, Psychopharmacology 232, 1107-1122 (2015).
18. A. Ahnaou, L. Raeymaekers, T. Steckler, W. H. Drinkenbrug, Behav. Brain Res. 282, 218-226 (2015).
19. S. Maret et al., Proc. Natl. Acad. Sci. U.S.A. 104, 20090-20095 (2007).
20. M. Mackiewicz, B. Paigen, N. Naidoo, A. I. Pack, Physiol. Genomics 33, 91-99 (2008).
21. J. C. Tu et al., Neuron 23, 583-592 (1999).
22. F. Ango et al., Nature 411, 962-965 (2001).
23. K. L. Eckel-Mahan et al., Nat. Neurosci. 11, 1074-1082 (2008).
24. S. Thandi, J. L. Blank, R. A. Challiss, J. Neurochem. 83, 1139-1153 (2002).
25. D. Chaudhury, C. S. Colwell, Behav. Brain Res. 133, 95-108 (2002).
26. G. Aston-Jones, F. E. Bloom, J. Neurosci. 1, 876-886 (1981).
27. T. E. Bjorness et al., J. Neurosci. 36, 3709-3721 (2016).
28. Z. Chen et al., J. Neurosci. 34, 9621-9643 (2014).
29. T. Serchov et al., Neuron 87, 549-562 (2015).
30. B. O. Watson, D. Levenstein, J. P. Greene, J. N. Gelinas, G. Buzsáki, Neuron 90, 839-852 (2016).