Reduction in necrotizing enterocolitis and improved outcomes in preterm infants following routine supplementation with Lactobacillus GG in combination with bovine lactoferrin

Journal of Neonatal-Perinatal Medicine

Volumn 10, Issue 3, 2017, Pages 249-255

  Meyer, Michael P ^a,b   Alexander, Tanith ^a  

^a MIDDLEMORE HOSPITAL   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Lactobacillus GG; lactoferrin; Necrotizing enterocolitis; preterm infant; probiotics

Indexed keywords

LACTOFERRIN; PROBIOTIC AGENT;

ADVERSE OUTCOME; ARTICLE; BIRTH WEIGHT; BLOOD CULTURE; BLOOD TRANSFUSION; CEREBROSPINAL FLUID CULTURE; CLINICAL PRACTICE; COHORT ANALYSIS; COLONY FORMING UNIT; CONTROLLED STUDY; COST CONTROL; DISEASE COURSE; FEMALE; GESTATIONAL AGE; HUMAN; INCIDENCE; INFANT; LACTOBACILLUS; LACTOBACILLUS GG; LACTOBACILLUS RHAMNOSUS; NECROTIZING ENTEROCOLITIS; NONHUMAN; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; PREMATURITY; PRIORITY JOURNAL; PROPHYLAXIS; RETINOPATHY; RETROSPECTIVE STUDY; SEPSIS; SUPPLEMENTATION; ANIMAL; BOVINE; CASE CONTROL STUDY; DIETARY SUPPLEMENT; EXTREMELY LOW BIRTH WEIGHT; MALE; NEW ZEALAND; NEWBORN; NEWBORN SEPSIS; SEVERITY OF ILLNESS INDEX; VERY LOW BIRTH WEIGHT;

ANIMALS; CASE-CONTROL STUDIES; CATTLE; COHORT STUDIES; DIETARY SUPPLEMENTS; ENTEROCOLITIS, NECROTIZING; FEMALE; HUMANS; INFANT, EXTREMELY LOW BIRTH WEIGHT; INFANT, EXTREMELY PREMATURE; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, VERY LOW BIRTH WEIGHT; LACTOBACILLUS RHAMNOSUS; LACTOFERRIN; MALE; NEONATAL SEPSIS; NEW ZEALAND; PROBIOTICS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 85031824996     PISSN: 19345798     EISSN: 18784429     Source Type: Journal    
DOI: 10.3233/NPM-16130     Document Type: Article

References (38)

1. Neu J. Probiotics and necrotizing enterocolitis. Clin Perinatol 2014;41:267-78.
2. Neu J, Walker WA. Necrotizing enterocolitis. New Engl J Med 2011;364:255-64.
3. Kasivajjula H, Maheshwari A. Pathophysiology and current management of necrotizing enterocolitis. Indian J Pediatr 2014;81:489-97.
4. Chow SSW, Le Marsney R, Hossain S, et al. Report of the Australian and New Zealand Neonatal Network 2013, Sydney: ANZNN 2015.
5. Gordon P, Christensen R, Weitkamp JH, et al. Mapping the new world of necrotizing enterocolitis (NEC): Review and opinion. EJ Neonatol Res 2012;2:145-72.
6. Cotton CM, Taylor S, Stoll E, et al. Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of nectrotizing enterocolitis and death for extremely low birth weight infants. Pediatrics 2009;123:58- 66.
7. Claud EC. Neonatal necrotizing enterocolitis-inflammation and intestinal immaturity. Antiinflamm Antiallergy Agents Med Chem 2009;8:248-59.
8. Sullivan S, Schanler RJ, Kim JH, et al. An exclusively human milk-based diet is associated with a lower rate of necrotizing enterocolitis than a diet of human milk and bovine milk-based products. J Pediatr 2010;156:562e1-7e1.
9. AlFaleh K, Anabrees J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev 2014;(4). Art. No.:CD005496.
10. Manzoni P, Rinaldi M, Cattani S, et al. Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: A randomized trial. JAMA 2009;302:1421-8.
11. Sanchez, CalvoM, Brock JH. Biological role of lactoferrin. Arch Dis Child 1992;67:657-61.
12. Pammi M, Abrams SA. Oral lactoferrin in the prevention of sepsis and enterocolitis in preterm infants. Cochrane Database Syst Rev 2015;(2). Art. No:CD007137.
13. Manzoni P, Meyer M, Stolfi I, et al. Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: A randomized clinical trial. Early Hum Dev 2014;90(Suppl 1):S60-5.
14. Hickey L, Garland SM, Jacobs SE, et al. Cross-colonization of infants with probiotic organisms in a neonatal unit. J Hosp Infect 2014;88:226-9.
15. Bell MJ, Ternberg JL, Feigin RD, et al. Neonatal necrotizing enterocolitis: Therapeutic decisions based upon clinical staging. Ann Surg 1978;187:1-7.
16. Gordon PV. Understanding intestinal vulnerability to perforation in the extremely low birth weight infant. Pediatr Res 2009;65:138-44.
17. American Academy of Pediatrics. Screening examination of premature infants for retinopathy of prematurity. Pediatrics 2013;131:189-95.
18. Early treatment for retinopathy of prematurity cooperative group. Revised indications for the treatment of retinopathy of prematurity: Results of the early treatment for retinopathy of prematurity randomised trial. Arch Ophthalmol 2013;121:1684-94.
19. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Multicenter trial of cryotherapy for retinopathy of prematurity: Preliminary results. Pediatrics 1988;81:697- 706.
20. Patel BK, Shah JS. Necrotizing enterocolitis in very low birth weight infants:Asystemic review. ISRN Gastroenterol 2012;2012:562594.
21. Meyer M, Manzoni P. Lactobacillus GG as probiotic for prevention of necrotizing enterocolitis or late onset sepsis in preterm infants: An updated meta-analysis. [abstract] Early Human Dev 2013;89SI:S75-91.
22. Luoto R, Isolauri E, Lehtonen L. Safety of Lactobacillus GG probiotic in infants with very low birth weight: Twelve years of experience. Clin Infect Dis 2010;50:1327-8.
23. Luoto R, Matomäki J, Isolauri E, et al. Incidence of necrotizing enterocolitis in very-low-birth-weight infants related to the use of Lactobacillus GG. Acta Paediatrica 2010;99:1135-8.
24. Rahman MM, Kim WS, Ito T, et al. Growth promotion and cell binding ability of bovine lactoferrin to Bifidobacterium longum. Anaerobe 2009;15:133-7.
25. Bonsante F, Iacobelli S, Gouyon JB. Routine probiotic use in very preterm infants: Retrospective comparison of two cohorts. Am J Perinatol 2013;30:41-6.
26. Costeloe K,Wilks M, Hardy P, et al. Bifidobacterium breve BBG-001 (B Breve) to prevent nectrotizing enterocolitis (NEC), late onset sepsis (LOS) and death: The PIPS trial. [abstract] J Paediatric Child Health 2015;51(Suppl 1):67.
27. Manzoni P, Lista G, Gallo E. Routine Lactobacillus rhamnosusGGadministration inVLBWinfants:Aretrospective, 6-year cohort study. Early Hum Dev 2011;87S:S35-8.
28. Kunz AN, Noel JM, Fairchok MP. Two cases of Lactobacilus bacteremia during probiotic treatment of short gut syndrome. J Pediatr Gastroenterol Nutr 2004;38:457-8.
29. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
30. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60:924-7.
31. Jenke A, Ruf EM, Hoppe T, et al. Bifidobacterium septicaemia in an extremely low-birthweight infant under probiotic therapy. Arch Dis Child Fetal Neonatal Ed 2012;97:F217-8.
32. Tran L, Bégué RE, Penn D. Lactobacillus rhamnosus sepsis in an infant without probiotic use: A case report and literature review. J Neonatal Perinatal Med 2011;4:163-7.
33. Weisz B, Hogen L, Yinon Y, et al. Perinatal outcome of monochorionic twins with selective IUGR compared with uncomplicated monochorionic twins. Twin Res Hum Genet 2011;14:457-62.
34. Bisquera JA, Cooper TR, Berseth CL. Impact of necrotizing enterocolitis on length of stay and hospital charges in very low birth weight infants. Pediatrics 2002;109:423-8.
35. Ganapathy V, Hay JW, Kim JH. Costs of necrotizing enterocolitis and cost-effectiveness of exclusively human milk-based products in feeding extremely premature infants. Breastfeed Med 2012;7:29-37.
36. Stey A, Barnert ES, Tseng CH, et al. Outcomes and costs of surgical treatments of necrotizing enterocolitis. Pediatrics 2015;135:e1190-7.
37. Li S-Y, Fu ZJ, Lo AC. Hypoxia-induced oxidative stress in ischemic retinopathy. Oxid Med Cell Longev 2012;2012:426769.
38. Meyer MP. Bronchopulmonary dysplasia and erythropoietin. Neonatology 2013;103:123.