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Volumn 18, Issue 11, 2017, Pages 1228-1237

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8 + T cell response

(20)  Culshaw, Abigail a   Ladell, Kristin b   Gras, Stephanie c   McLaren, James E b   Miners, Kelly L b   Farenc, Carine c   Van Den Heuvel, Heleen c   Gostick, Emma b   Dejnirattisai, Wanwisa a   Wangteeraprasert, Apirath a,j   Duangchinda, Thaneeya d   Chotiyarnwong, Pojchong a,g,j   Limpitikul, Wannee e   Vasanawathana, Sirijitt f   Malasit, Prida g   Dong, Tao h   Rossjohn, Jamie b,c   Mongkolsapaya, Juthathip a,g   Price, David A b,i   Screaton, Gavin R a  


Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; T LYMPHOCYTE RECEPTOR; COMPLEMENTARITY DETERMINING REGION; HLA A ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; NS3 PROTEASE, DENGUE VIRUS; SERINE PROTEINASE;

EID: 85031784242     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3850     Document Type: Article
Times cited : (34)

References (56)
  • 1
    • 84876804736 scopus 로고    scopus 로고
    • The global distribution and burden of dengue
    • Bhatt, S. et al. The global distribution and burden of dengue. Nature 496, 504-507 (2013).
    • (2013) Nature , vol.496 , pp. 504-507
    • Bhatt, S.1
  • 2
    • 0021702322 scopus 로고
    • Risk factors in dengue shock syndrome: A prospective epidemiologic study in Rayong, Thailand. I. The 1980 outbreak
    • Sangkawibha, N. et al. Risk factors in dengue shock syndrome: A prospective epidemiologic study in Rayong, Thailand. I. The 1980 outbreak. Am. J. Epidemiol. 120, 653-669 (1984).
    • (1984) Am. J. Epidemiol. , vol.120 , pp. 653-669
    • Sangkawibha, N.1
  • 3
    • 0034331203 scopus 로고    scopus 로고
    • Epidemiologic studies on Dengue in Santiago de Cuba, 1997
    • discussion 804
    • Guzmán, M. G. et al. Epidemiologic studies on Dengue in Santiago de Cuba, 1997. Am. J. Epidemiol. 152, 793-799, discussion 804 (2000).
    • (2000) Am. J. Epidemiol. , vol.152 , pp. 793-799
    • Guzmán, M.G.1
  • 4
    • 0642287817 scopus 로고    scopus 로고
    • Neutralization and antibody-dependent enhancement of dengue viruses
    • Halstead, S. B. Neutralization and antibody-dependent enhancement of dengue viruses. Adv. Virus Res. 60, 421-467 (2003).
    • (2003) Adv. Virus Res. , vol.60 , pp. 421-467
    • Halstead, S.B.1
  • 5
    • 0023181358 scopus 로고
    • Study of the distribution of antibodydependent enhancement determinants on dengue 2 isolates using dengue 2-derived monoclonal antibodies
    • Morens, D. M., Larsen, L. K. & Halstead, S. B. Study of the distribution of antibodydependent enhancement determinants on dengue 2 isolates using dengue 2-derived monoclonal antibodies. J. Med. Virol. 22, 163-167 (1987).
    • (1987) J. Med. Virol. , vol.22 , pp. 163-167
    • Morens, D.M.1    Larsen, L.K.2    Halstead, S.B.3
  • 6
    • 0025361063 scopus 로고
    • Human IgG Fc receptor II mediates antibodydependent enhancement of dengue virus infection
    • Littaua, R., Kurane, I. & Ennis, F. A. Human IgG Fc receptor II mediates antibodydependent enhancement of dengue virus infection. J. Immunol. 144, 3183-3186 (1990).
    • (1990) J. Immunol. , vol.144 , pp. 3183-3186
    • Littaua, R.1    Kurane, I.2    Ennis, F.A.3
  • 7
    • 0015795032 scopus 로고
    • Studies on the pathogenesis of dengue infection in monkeys. 3. Sequential distribution of virus in primary and heterologous infections
    • Marchette, N. J., Halstead, S. B., Falkler, W. A. Jr., Stenhouse, A. & Nash, D. Studies on the pathogenesis of dengue infection in monkeys. 3. Sequential distribution of virus in primary and heterologous infections. J. Infect. Dis. 128, 23-30 (1973).
    • (1973) J. Infect. Dis. , vol.128 , pp. 23-30
    • Marchette, N.J.1    Halstead, S.B.2    Falkler, W.A.3    Stenhouse, A.4    Nash, D.5
  • 8
    • 0015784492 scopus 로고
    • Studies on the pathogenesis of dengue infection in monkeys. II. Clinical laboratory responses to heterologous infection
    • Halstead, S. B., Shotwell, H. & Casals, J. Studies on the pathogenesis of dengue infection in monkeys. II. Clinical laboratory responses to heterologous infection. J. Infect. Dis. 128, 15-22 (1973).
    • (1973) J. Infect. Dis. , vol.128 , pp. 15-22
    • Halstead, S.B.1    Shotwell, H.2    Casals, J.3
  • 9
    • 76249103868 scopus 로고    scopus 로고
    • Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease
    • Zellweger, R. M., Prestwood, T. R. & Shresta, S. Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease. Cell Host Microbe 7, 128-139 (2010).
    • (2010) Cell Host Microbe , vol.7 , pp. 128-139
    • Zellweger, R.M.1    Prestwood, T.R.2    Shresta, S.3
  • 10
    • 0036569001 scopus 로고    scopus 로고
    • Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections
    • Libraty, D. H. et al. Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections. J. Infect. Dis. 185, 1213-1221 (2002).
    • (2002) J. Infect. Dis. , vol.185 , pp. 1213-1221
    • Libraty, D.H.1
  • 11
    • 20244381983 scopus 로고    scopus 로고
    • Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections
    • Simmons, C. P. et al. Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections. J. Virol. 79, 5665-5675 (2005).
    • (2005) J. Virol. , vol.79 , pp. 5665-5675
    • Simmons, C.P.1
  • 12
    • 78049244414 scopus 로고    scopus 로고
    • Immunodominant T-cell responses to dengue virus NS3 are associated with DHF
    • Duangchinda, T. et al. Immunodominant T-cell responses to dengue virus NS3 are associated with DHF. Proc. Natl. Acad. Sci. USA 107, 16922-16927 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 16922-16927
    • Duangchinda, T.1
  • 13
    • 84878446213 scopus 로고    scopus 로고
    • Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells
    • Weiskopf, D. et al. Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells. Proc. Natl. Acad. Sci. USA 110, E2046-E2053 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. E2046-E2053
    • Weiskopf, D.1
  • 14
    • 84887312543 scopus 로고    scopus 로고
    • Role of humoral versus cellular responses induced by a protective dengue vaccine candidate
    • Zellweger, R. M. et al. Role of humoral versus cellular responses induced by a protective dengue vaccine candidate. PLoS Pathog. 9, e1003723 (2013).
    • (2013) PLoS Pathog. , vol.9 , pp. e1003723
    • Zellweger, R.M.1
  • 15
    • 84929598310 scopus 로고    scopus 로고
    • CD8+ T cells can mediate short-term protection against heterotypic dengue virus reinfection in mice
    • Zellweger, R. M. et al. CD8+ T cells can mediate short-term protection against heterotypic dengue virus reinfection in mice. J. Virol. 89, 6494-6505 (2015).
    • (2015) J. Virol. , vol.89 , pp. 6494-6505
    • Zellweger, R.M.1
  • 16
    • 84920585186 scopus 로고    scopus 로고
    • Efficacy of a tetravalent dengue vaccine in children in Latin America
    • Villar, L. et al. Efficacy of a tetravalent dengue vaccine in children in Latin America. N. Engl. J. Med. 372, 113-123 (2015).
    • (2015) N. Engl. J. Med. , vol.372 , pp. 113-123
    • Villar, L.1
  • 17
    • 0030960866 scopus 로고    scopus 로고
    • HLA-A,-B,-DRB1,-DQA1, and-DQB1 polymorphism in Thais
    • Chandanayingyong, D. et al. HLA-A,-B,-DRB1,-DQA1, and-DQB1 polymorphism in Thais. Hum. Immunol. 53, 174-182 (1997).
    • (1997) Hum. Immunol. , vol.53 , pp. 174-182
    • Chandanayingyong, D.1
  • 18
    • 77953646070 scopus 로고    scopus 로고
    • Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue
    • Dung, N. T. et al. Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue. J. Immunol. 184, 7281-7287 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 7281-7287
    • Dung, N.T.1
  • 19
    • 0038379214 scopus 로고    scopus 로고
    • Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever
    • Mongkolsapaya, J. et al. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat. Med. 9, 921-927 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 921-927
    • Mongkolsapaya, J.1
  • 20
    • 83055179941 scopus 로고    scopus 로고
    • Structural and biophysical determinants of T-cell antigen recognition
    • Bridgeman, J. S., Sewell, A. K., Miles, J. J., Price, D. A. & Cole, D. K. Structural and biophysical determinants of T-cell antigen recognition. Immunology 135, 9-18 (2012).
    • (2012) Immunology , vol.135 , pp. 9-18
    • Bridgeman, J.S.1    Sewell, A.K.2    Miles, J.J.3    Price, D.A.4    Cole, D.K.5
  • 21
    • 84927661328 scopus 로고    scopus 로고
    • T cell antigen receptor recognition of antigen-presenting molecules
    • Rossjohn, J. et al. T cell antigen receptor recognition of antigen-presenting molecules. Annu. Rev. Immunol. 33, 169-200 (2015).
    • (2015) Annu. Rev. Immunol. , vol.33 , pp. 169-200
    • Rossjohn, J.1
  • 22
    • 84944879331 scopus 로고    scopus 로고
    • T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex
    • Beringer, D. X. et al. T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nat. Immunol. 16, 1153-1161 (2015).
    • (2015) Nat. Immunol. , vol.16 , pp. 1153-1161
    • Beringer, D.X.1
  • 23
    • 84994885777 scopus 로고    scopus 로고
    • Reversed T cell receptor docking on a major histocompatibility class i complex limits involvement in the immune response
    • Gras, S. et al. Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response. Immunity 45, 749-760 (2016).
    • (2016) Immunity , vol.45 , pp. 749-760
    • Gras, S.1
  • 24
    • 79959353928 scopus 로고    scopus 로고
    • Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses
    • Day, E. B. et al. Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses. Proc. Natl. Acad. Sci. USA 108, 9536-9541 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 9536-9541
    • Day, E.B.1
  • 25
    • 77954411152 scopus 로고    scopus 로고
    • Allelic polymorphism in the T cell receptor and its impact on immune responses
    • Gras, S. et al. Allelic polymorphism in the T cell receptor and its impact on immune responses. J. Exp. Med. 207, 1555-1567 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 1555-1567
    • Gras, S.1
  • 26
    • 24744457740 scopus 로고    scopus 로고
    • CTL recognition of a bulged viral peptide involves biased TCR selection
    • Miles, J. J. et al. CTL recognition of a bulged viral peptide involves biased TCR selection. J. Immunol. 175, 3826-3834 (2005).
    • (2005) J. Immunol. , vol.175 , pp. 3826-3834
    • Miles, J.J.1
  • 27
    • 84952639169 scopus 로고    scopus 로고
    • Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity
    • Adams, J. J. et al. Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat. Immunol. 17, 87-94 (2016).
    • (2016) Nat. Immunol. , vol.17 , pp. 87-94
    • Adams, J.J.1
  • 28
    • 34548128306 scopus 로고    scopus 로고
    • Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
    • Feng, D., Bond, C. J., Ely, L. K., Maynard, J. & Garcia, K. C. Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'. Nat. Immunol. 8, 975-983 (2007).
    • (2007) Nat. Immunol. , vol.8 , pp. 975-983
    • Feng, D.1    Bond, C.J.2    Ely, L.K.3    Maynard, J.4    Garcia, K.C.5
  • 29
    • 81955161800 scopus 로고    scopus 로고
    • A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands
    • Stadinski, B. D. et al. A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands. Immunity 35, 694-704 (2011).
    • (2011) Immunity , vol.35 , pp. 694-704
    • Stadinski, B.D.1
  • 30
    • 0035577034 scopus 로고    scopus 로고
    • Strong HLA class I-restricted T cell responses in dengue hemorrhagic fever: A double-edged sword
    • Loke, H. et al. Strong HLA class I-restricted T cell responses in dengue hemorrhagic fever: A double-edged sword J. Infect. Dis. 184, 1369-1373 (2001).
    • (2001) J. Infect. Dis. , vol.184 , pp. 1369-1373
    • Loke, H.1
  • 31
    • 56149090610 scopus 로고    scopus 로고
    • Protective and enhancing HLA alleles, HLA-DRB10901 and HLA-A24, for severe forms of dengue virus infection, dengue hemorrhagic fever and dengue shock syndrome
    • Nguyen, T. P. et al. Protective and enhancing HLA alleles, HLA-DRB10901 and HLA-A24, for severe forms of dengue virus infection, dengue hemorrhagic fever and dengue shock syndrome. PLoS Negl. Trop. Dis. 2, e304 (2008).
    • (2008) PLoS Negl. Trop. Dis. , vol.2 , pp. e304
    • Nguyen, T.P.1
  • 32
    • 77958570771 scopus 로고    scopus 로고
    • Susceptible and protective HLA class 1 alleles against dengue fever and dengue hemorrhagic fever patients in a Malaysian population
    • Appanna, R., Ponnampalavanar, S., Lum Chai See, L. & Sekaran, S. D. Susceptible and protective HLA class 1 alleles against dengue fever and dengue hemorrhagic fever patients in a Malaysian population. PLoS One 5, e13029 (2010).
    • (2010) PLoS One , vol.5 , pp. e13029
    • Appanna, R.1    Ponnampalavanar, S.2    Lum Chai See, L.3    Sekaran, S.D.4
  • 33
    • 79958244258 scopus 로고    scopus 로고
    • HLA class i and class II associations in dengue viral infections in a Sri Lankan population
    • Malavige, G. N. et al. HLA class I and class II associations in dengue viral infections in a Sri Lankan population. PLoS One 6, e20581 (2011).
    • (2011) PLoS One , vol.6 , pp. e20581
    • Malavige, G.N.1
  • 34
    • 0036818735 scopus 로고    scopus 로고
    • HLA-A and-B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais
    • Stephens, H. A. et al. HLA-A and-B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens 60, 309-318 (2002).
    • (2002) Tissue Antigens , vol.60 , pp. 309-318
    • Stephens, H.A.1
  • 35
    • 84940775622 scopus 로고    scopus 로고
    • HLA class i supertype associations with clinical outcome of secondary dengue virus infections in ethnic Thais
    • Vejbaesya, S. et al. HLA class I supertype associations with clinical outcome of secondary dengue virus infections in ethnic Thais. J. Infect. Dis. 212, 939-947 (2015).
    • (2015) J. Infect. Dis. , vol.212 , pp. 939-947
    • Vejbaesya, S.1
  • 36
    • 0024446830 scopus 로고
    • Dengue haemorrhagic fever/ dengue shock syndrome: Lessons from the Cuban epidemic, 1981
    • Kouri, G. P., Guzmán, M. G., Bravo, J. R. & Triana, C. Dengue haemorrhagic fever/ dengue shock syndrome: lessons from the Cuban epidemic, 1981. Bull. World Health Organ. 67, 375-380 (1989).
    • (1989) Bull. World Health Organ. , vol.67 , pp. 375-380
    • Kouri, G.P.1    Guzmán, M.G.2    Bravo, J.R.3    Triana, C.4
  • 37
    • 33747310786 scopus 로고    scopus 로고
    • Dengue hemorrhagic fever caused by sequential dengue 1-3 virus infections over a long time interval: Havana epidemic, 2001-2002
    • Alvarez, M. et al. Dengue hemorrhagic fever caused by sequential dengue 1-3 virus infections over a long time interval: Havana epidemic, 2001-2002. Am. J. Trop. Med. Hyg. 75, 1113-1117 (2006).
    • (2006) Am. J. Trop. Med. Hyg. , vol.75 , pp. 1113-1117
    • Alvarez, M.1
  • 38
    • 84255168505 scopus 로고    scopus 로고
    • Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity
    • OhAinle, M. et al. Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity. Sci. Transl. Med. 3, 114ra128 (2011).
    • (2011) Sci. Transl. Med. , vol.3 , pp. 114ra128
    • OhAinle, M.1
  • 39
    • 33644838912 scopus 로고    scopus 로고
    • T cell responses in dengue hemorrhagic fever: Are crossreactive T cells suboptimal
    • Mongkolsapaya, J. et al. T cell responses in dengue hemorrhagic fever: Are crossreactive T cells suboptimal J. Immunol. 176, 3821-3829 (2006).
    • (2006) J. Immunol , vol.176 , pp. 3821-3829
    • Mongkolsapaya, J.1
  • 40
    • 48749095596 scopus 로고    scopus 로고
    • Dengue in Vietnamese infants-results of infection-enhancement assays correlate with age-related disease epidemiology, and cellular immune responses correlate with disease severity
    • Chau, T. N. et al. Dengue in Vietnamese infants-results of infection-enhancement assays correlate with age-related disease epidemiology, and cellular immune responses correlate with disease severity. J. Infect. Dis. 198, 516-524 (2008).
    • (2008) J. Infect. Dis. , vol.198 , pp. 516-524
    • Chau, T.N.1
  • 41
    • 78651083977 scopus 로고    scopus 로고
    • Memory CD8+ T cells from naturally acquired primary dengue virus infection are highly cross-reactive
    • Friberg, H. et al. Memory CD8+ T cells from naturally acquired primary dengue virus infection are highly cross-reactive. Immunol. Cell Biol. 89, 122-129 (2011).
    • (2011) Immunol. Cell Biol. , vol.89 , pp. 122-129
    • Friberg, H.1
  • 42
    • 0030154667 scopus 로고    scopus 로고
    • Rapid detection and identification of dengue viruses by polymerase chain reaction (PCR)
    • Yenchitsomanus, P. T. et al. Rapid detection and identification of dengue viruses by polymerase chain reaction (PCR). Southeast Asian J. Trop. Med. Public Health 27, 228-236 (1996).
    • (1996) Southeast Asian J. Trop. Med. Public Health , vol.27 , pp. 228-236
    • Yenchitsomanus, P.T.1
  • 43
    • 0024580765 scopus 로고
    • An enzyme-linked immunosorbent assay to characterize dengue infections where dengue and Japanese encephalitis co-circulate
    • Innis, B. L. et al. An enzyme-linked immunosorbent assay to characterize dengue infections where dengue and Japanese encephalitis co-circulate. Am. J. Trop. Med. Hyg. 40, 418-427 (1989).
    • (1989) Am. J. Trop. Med. Hyg. , vol.40 , pp. 418-427
    • Innis, B.L.1
  • 44
    • 0030669795 scopus 로고    scopus 로고
    • The microfocus reduction neutralization test for determining dengue and Japanese encephalitis neutralizing antibodies in volunteers vaccinated against dengue
    • Jirakanjanakit, N., Sanohsomneing, T., Yoksan, S. & Bhamarapravati, N. The microfocus reduction neutralization test for determining dengue and Japanese encephalitis neutralizing antibodies in volunteers vaccinated against dengue. Trans. R. Soc. Trop. Med. Hyg. 91, 614-617 (1997).
    • (1997) Trans. R. Soc. Trop. Med. Hyg. , vol.91 , pp. 614-617
    • Jirakanjanakit, N.1    Sanohsomneing, T.2    Yoksan, S.3    Bhamarapravati, N.4
  • 46
    • 80055056100 scopus 로고    scopus 로고
    • Unbiased molecular analysis of T cell receptor expression using template-switch anchored RT-PCR
    • Unit 10:33 Wiley
    • Quigley, M. F., Almeida, J. R., Price, D. A. & Douek, D. C. Unbiased molecular analysis of T cell receptor expression using template-switch anchored RT-PCR. in Current Protocols in Immunology. Ch. 10, Unit 10:33 (Wiley, 2011).
    • (2011) Current Protocols in Immunology. Ch. 10
    • Quigley, M.F.1    Almeida, J.R.2    Price, D.A.3    Douek, D.C.4
  • 47
    • 13444312023 scopus 로고    scopus 로고
    • IMGT, the international ImMunoGeneTics information system
    • Lefranc, M. P. et al. IMGT, the international ImMunoGeneTics information system. Nucleic Acids Res. 33, D593-D597 (2005).
    • (2005) Nucleic Acids Res. , vol.33 , pp. D593-D597
    • Lefranc, M.P.1
  • 48
    • 60149111426 scopus 로고    scopus 로고
    • The shaping of T cell receptor recognition by self-tolerance
    • Gras, S. et al. The shaping of T cell receptor recognition by self-tolerance. Immunity 30, 193-203 (2009).
    • (2009) Immunity , vol.30 , pp. 193-203
    • Gras, S.1
  • 49
    • 14244273313 scopus 로고    scopus 로고
    • The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state
    • Clements, C. S. et al. The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state. Acta Crystallogr. D Biol. Crystallogr. 58, 2131-2134 (2002).
    • (2002) Acta Crystallogr. D Biol. Crystallogr. , vol.58 , pp. 2131-2134
    • Clements, C.S.1
  • 50
    • 0029881469 scopus 로고    scopus 로고
    • Production and crystallization of MHC class i B allele single peptide complexes
    • Reid, S. W. et al. Production and crystallization of MHC class I B allele single peptide complexes. FEBS Lett. 383, 119-123 (1996).
    • (1996) FEBS Lett. , vol.383 , pp. 119-123
    • Reid, S.W.1
  • 53
    • 0035788107 scopus 로고    scopus 로고
    • Pushing the boundaries of molecular replacement with maximum likelihood
    • Read, R. J. Pushing the boundaries of molecular replacement with maximum likelihood. Acta Crystallogr. D Biol. Crystallogr. 57, 1373-1382 (2001).
    • (2001) Acta Crystallogr. D Biol. Crystallogr. , vol.57 , pp. 1373-1382
    • Read, R.J.1
  • 54
    • 68949108186 scopus 로고    scopus 로고
    • Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope
    • Gras, S. et al. Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J. Immunol. 183, 430-437 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 430-437
    • Gras, S.1
  • 56
    • 13944262009 scopus 로고    scopus 로고
    • The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition
    • Borg, N. A. et al. The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition. Nat. Immunol. 6, 171-180 (2005).
    • (2005) Nat. Immunol. , vol.6 , pp. 171-180
    • Borg, N.A.1


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