A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome

Kidney International

Volumn 93, Issue 2, 2018, Pages 439-449

  Nair, Viji ^a,h   Komorowsky, Claudiu V ^a,h,i   Weil, E Jennifer ^b   Yee, Berne ^c   Hodgin, Jeffrey ^d   Harder, Jennifer L ^a   Godfrey, Bradley ^a   Ju, Wenjun ^a,d   Boustany Kari, Carine M ^e   Schwarz, Margrit ^e   Lemley, Kevin V ^f   Nelson, Peter J ^g   Nelson, Robert G ^b   Kretzler, Matthias ^a,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c Southwest Kidney Institute   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^g UNIVERSITY OF MUNICH   (Germany)

^h NONE

ⁱ UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

diabetic nephropathy; longitudinal phenotype; morphogenomics; pathway networks; transcriptomic profiling

Indexed keywords

ALBUMIN; CREATININE; PROTEIN P53; MESSENGER RNA; TRANSCRIPTOME;

ADULT; ARTICLE; CLINICAL ARTICLE; CREATININE URINE LEVEL; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; FUNCTIONAL ASSESSMENT; GENE EXPRESSION PROFILING; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN TISSUE; INDIAN; KIDNEY BIOPSY; KIDNEY CORTEX; KIDNEY STRUCTURE; LONGITUDINAL STUDY; MALE; MOLECULAR DYNAMICS; MORPHOMETRY; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN URINE LEVEL; QUANTITATIVE ANALYSIS; TRANSCRIPTION REGULATION; UPREGULATION; AMERICAN INDIAN; CHEMISTRY; DISEASE EXACERBATION; EPIDEMIOLOGY; ETHNOLOGY; GENE REGULATORY NETWORK; GENETIC MARKER; GENETIC PREDISPOSITION; GENETIC TRANSCRIPTION; GENETICS; KIDNEY; MIDDLE AGED; PHENOTYPE; PROCEDURES; RANDOMIZED CONTROLLED TRIAL (TOPIC); SIGNAL TRANSDUCTION; TIME FACTOR; ULTRASTRUCTURE; UNITED STATES;

ADULT; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GLOMERULAR FILTRATION RATE; HUMANS; INDIANS, NORTH AMERICAN; KIDNEY; MALE; MIDDLE AGED; PHENOTYPE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTOME; UNITED STATES;

EID: 85031670298     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2017.08.013     Document Type: Article

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