Antidiabetic effects of Salvia triloba and Thymus praecox subsp. Skorpilii var. skorpilii in a rat model of streptozotocin/nicotinamide-induced diabetes

Marmara Pharmaceutical Journal

Volumn 21, Issue 4, 2017, Pages 818-827

  Çam, Muhammet Emin ^a   Yildiz, Sıla ^a   Ertaş, Büşra ^a   Acar, Ayşe Eda ^a   Taşkin, Turgut ^a   Kabasakal, Levent ^a  

^a MARMARA UNIVERSITY   (Turkey)

Author keywords

Antidiabetic; Herbal medicines; Salvia triloba; Streptozotocin Nicotinamide; Thymuspraecox; Type II diabetes mellitus

Indexed keywords

ANTIDIABETIC AGENT; HUMAN INSULIN; METFORMIN; SALVIA TRILOBA EXTRACT; THYMUS PRAECOX EXTRACT; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; LAMIACEAE; MEDICINAL PLANT; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; RAT; SALVIA TRILOBA; SOXHLET EXTRACTION; STREPTOZOTOCIN NICOTINAMIDE-INDUCED DIABETES MELLITUS; THYMUS PRAECOX;

EID: 85031413374     PISSN: None     EISSN: 13090801     Source Type: Journal    
DOI: 10.12991/mpj.2017.8     Document Type: Article

References (24)

1. Azaz AD, Irtem HA, Kurkcuoglu M, Baser KHC. Composition and the in vitro antimicrobial activities of the essential oils of some Thymus species. Z Naturforsch 2004; 59c: 75-80.
2. Soleimani Farsani M, Behbahani M, Isfahani HZ. The effect of root, shoot and seed extracts of the Iranian Thymus L. (Family: Lamiaceae) species on HIV-1 replication and CD4 Expression. Cell J 2016; 18: 255-61.
3. Ozen T, Demirtas I, Aksit H. Determination of antioxidant activities of various extracts and essential oil compositions of Thymus praecox subsp. skorpilii var. skorpilii. Food Chem 2011; 124: 58-64.
4. Cvetkovikj I, Stefkov G, Karapandzova M, Kulevanova S. Essential oil composition of Salvia fruticosa Mill. populations from Balkan Peninsula. Macedonian Pharm Bull 2015; 61: 19-26.
5. Yucel E, Guney F, Yucel Sengun I. The wild plants consumed as a food in Mihalıççık district (Eskişehir:Turkey) and consumption forms of these plants. Biol Divers Conserv 2010; 3: 158-75.
6. American Diabetes A. Standards of medical care in diabetes-2016. Diabetes Care 2016; 39: 1-112.
7. American Diabetes A. Diagnosis and classification of diabetes mellitus. Diabetes Care 2012; 35: 64-71.
8. Abdelhafiz AH, Koay L, Sinclair AJ. The effect of frailty should be considered in the management plan of older people with Type 2 diabetes. Future Sci OA 2016; 2: FSO102.
9. Or T, Lm T, Mr P. Type 2 diabetes mellitus in children and adolescents: a relatively new clinical problem within pediatric practice. J Med Life 2016; 9: 235-9.
10. Shewamene Z, Abdelwuhab M, Birhanu Z. Methanolic leaf exctract of Otostegia integrifolia Benth reduces blood glucose levels in diabetic, glucose loaded and normal rodents. BMC Complement Altern Med 2015; 15: 19.
11. Abu-Abeeleh M. A preliminary study of the use of human adipose tissue-derived stem cells for the treatment of streptozotocin-induced diabetes mellitus in a rat model. Future Sci OA 2016; 2: FSO102.
12. Szkudelski T. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 2001; 50: 537-46.
13. Srinivasan K, Ramarao P. Animal models in type 2 diabetes research: An overview. Indian J Med Res 2007; 125: 451-72.
14. Deeds MC, Anderson JM, Armstrong AS, Gastineau DA, Hiddinga HJ, Jahangir A, Eberhardt JL, Kudva YC. Single dose streptozotocin induced diabetes: Considerations for study design in islet transplantation models. Lab Anim 2011; 45: 131-40.
15. Turkkan A, Savas HB, Yavuz B, Yigit A, Uz E, Bayram NA, Kale B. The prophylactic effect of Viscum album in streptozotocin-induced diabetic rats. North Clin Istanbul 2016; 3: 83-9.
16. Hossain MS, Ahmed M, Islam A. Hypolipidemic and hepatoprotective effect of different fraction of methanolic extract of Momordica charantia (Linn.) in alloxan induced diabetic rats. Int J Pharm Sci Res 2011; 2: 601-7.
17. Groop L. Genetics of the metabolic syndrome. Br J Nutr 2000; 83: 39-48.
18. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998; 15: 539-53.
19. Roberts CK, Hevener AL, Barnard RJ. Metabolic syndrome and insulin resistance: Underlying causes and modification by exercise training. Compr Physiol 2013; 3: 1-58.
20. Adam SH, Giribabu N, Rao PV, Sayem AS, Arya A, Panichayupakaranant P, Korla PK, Salleh N. Rhinacanthin C ameliorates hyperglycaemia, hyperlipidemia and pancreatic destruction in streptozotocin-nicotinamide induced adult male diabetic rats. Eur J Pharmacol 2016; 771: 173-90.
21. Emordi JE, Agbaje EO, Oreagba IA, Iribhogbe OI. Antidiabetic and hypolipidemic activities of hydroethanolic root extract of Uvaria chamae in streptozotocin induced diabetic albino rats. BMC Complement Altern Med 2016; 16: 468.
22. Bonora E, Moghetti P, Zancanaro C, Cigolini M, Querena M, Cacciatori V, Corgnati A, Muggeo M. Estimates of in vivo insulin action in man: Comparison of insulin tolerance tests with euglycemic and hyperglycemic glucose clamp studies. J Clin Endocrinol Metab 1989; 68: 374-8.
23. Tovchiga OV. The influence of goutweed (Aegopodium podagraria L.) tincture and metformin on the carbohydrate and lipid metabolism in dexamethasone-treated rats. BMC Complement Altern Med 2016; 16: 235.
24. Korec R. Diabetes diagnosis following intravenous and oral glucose load: animal experiment principles. Z Gesamte Inn Med 1988; 43: 427-9.