Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study

Clinical Immunology

Volumn 183, Issue , 2017, Pages 325-335

  Duffy, Darragh ^a,b   Rouilly, Vincent ^a   Braudeau, Cecile ^c,d   Corbière, Véronique ^e   Djebali, Raouf ^a   Ungeheuer, Marie Noelle ^a   Josien, Regis ^c,d,f   LaBrie, Samuel T ^g   Lantz, Olivier ^h   Louis, Delphine ^h   Martinez Caceres, Eva ⁱ   Mascart, Francoise ^e,j   Ruiz de Morales, Jose G ^k   Ottone, Catherine ^a   Redjah, Lydia ^e   Guen, Nina Salabert Le ^c,d,f   Savenay, Alain ^h   Schmolz, Manfred ^l   Toubert, Antoine ^h   Albert, Matthew L ^a,b,m  

^a INSTITUT PASTEUR   (France)

^b INSTITUT PASTEUR   (France)

^c NANTES UNIVERSITY HOSPITAL   (France)

^d UNIVERSITÉ DE NANTES   (France)

^e UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^f LabEx IGO Immunotherapy   (France)

^g Myriad RBM   (United States)

^h INSERM   (France)

ⁱ HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^j ERASME HOSPITAL   (Belgium)

^k Gerencia Regional de Salud de Castilla y León   (Spain)

^l HOT Screen GmbH   (Germany)

^m GENENTECH INC   (United States)

more..

Author keywords

Cytokines; Functional immune responses; Immunomonitoring; Multi center clinical studies; PBMCs; Whole blood

Indexed keywords

ALPHA INTERFERON; BLOOD CLOTTING FACTOR 7; BRAIN DERIVED NEUROTROPHIC FACTOR; CD28 ANTIGEN; CD3 ANTIBODY; DICKKOPF 1 PROTEIN; EOTAXIN; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; IMMUNOGLOBULIN E; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 16; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 3; INTERLEUKIN 31; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; STROMELYSIN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR; ANTIBODY; BIOLOGICAL MARKER; CD3 ANTIGEN; CD8 ANTIGEN; CYTOKINE;

ADAPTIVE IMMUNITY; ADULT; ARTICLE; BLOOD ANALYSIS; CHEMILUMINESCENCE IMMUNOASSAY; CLINICAL ASSESSMENT; CLINICAL PRACTICE; CLINICAL STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOASSAY; IMMUNOSTIMULATION; IMMUNOTHERAPY; LABORATORY TEST; MALE; MULTICENTER STUDY; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; POINT OF CARE TESTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; VACCINATION; BLOOD; BLOOD DONOR; CLINICAL TRIAL; DEVICES; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGICAL PROCEDURES; IMMUNOLOGY; METABOLISM; POINT OF CARE SYSTEM; PROCEDURES;

ANTIBODIES; BIOMARKERS; BLOOD DONORS; CD3 COMPLEX; CD8 ANTIGENS; CYTOKINES; GENE EXPRESSION REGULATION; HUMANS; IMMUNOLOGIC TESTS; LIPOPOLYSACCHARIDES; POINT-OF-CARE SYSTEMS;

EID: 85030632273     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2017.09.019     Document Type: Article

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