메뉴 건너뛰기




Volumn 5, Issue 7, 2017, Pages 987-996

Use of inhibitors of the renin–angiotensin system is associated with longer survival in patients with hepatocellular carcinoma

Author keywords

angiotensin II receptor blocker; angiotensin converting enzyme inhibitor; Hepatocellular carcinoma; renin angiotensin system; sorafenib

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ASPARTATE AMINOTRANSFERASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENZYME INHIBITOR; RAS INHIBITOR; SORAFENIB; UNCLASSIFIED DRUG;

EID: 85030548706     PISSN: 20506406     EISSN: 20506414     Source Type: Journal    
DOI: 10.1177/2050640617695698     Document Type: Article
Times cited : (41)

References (70)
  • 2
    • 83155175343 scopus 로고    scopus 로고
    • Clinical characteristics of patients with hepatocellular carcinoma in Austria – is there a need for a structured screening program?
    • Hucke F, Sieghart W, Schoniger-Hekele M, Clinical characteristics of patients with hepatocellular carcinoma in Austria – is there a need for a structured screening program? Wien Klin Wochenschr 2011; 123: 542–551.
    • (2011) Wien Klin Wochenschr , vol.123 , pp. 542-551
    • Hucke, F.1    Sieghart, W.2    Schoniger-Hekele, M.3
  • 3
    • 84858658381 scopus 로고    scopus 로고
    • EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma
    • European Association for the Study of the Liver. EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 2012; 56: 908–943.
    • (2012) J Hepatol , vol.56 , pp. 908-943
  • 4
    • 84994649513 scopus 로고    scopus 로고
    • Cancer and liver cirrhosis: implications on prognosis and management
    • Pinter M, Trauner M, Peck-Radosavljevic M, Cancer and liver cirrhosis: implications on prognosis and management. ESMO Open 2016; 1: e000042–e000042.
    • (2016) ESMO Open , vol.1 , pp. e000042
    • Pinter, M.1    Trauner, M.2    Peck-Radosavljevic, M.3
  • 5
    • 84890562275 scopus 로고    scopus 로고
    • Hepatocellular cancer: the impact of obesity, type 2 diabetes and a multidisciplinary team
    • Dyson J, Jaques B, Chattopadyhay D, Hepatocellular cancer: the impact of obesity, type 2 diabetes and a multidisciplinary team. J Hepatol 2014; 60: 110–117.
    • (2014) J Hepatol , vol.60 , pp. 110-117
    • Dyson, J.1    Jaques, B.2    Chattopadyhay, D.3
  • 6
    • 57349191046 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • Llovet JM, Ricci S, Mazzaferro V, Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378–390.
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3
  • 7
    • 85010444964 scopus 로고    scopus 로고
    • Efficacy and safety of regorafenib versus placebo in patients with hepatocellular carcinoma (HCC) progressing on sorafenib: results of the international, randomized phase 3 RESORCE trial
    • Bruix J, Merle P, Granito A, Efficacy and safety of regorafenib versus placebo in patients with hepatocellular carcinoma (HCC) progressing on sorafenib: results of the international, randomized phase 3 RESORCE trial. Ann Oncol 2016; 27(Suppl 2): ii140–ii140.
    • (2016) Ann Oncol , vol.27 , pp. ii140
    • Bruix, J.1    Merle, P.2    Granito, A.3
  • 8
    • 84898989382 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial design
    • Llovet JM, Hernandez-Gea V. Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial design. Clin Cancer Res 2014; 20: 2072–2079.
    • (2014) Clin Cancer Res , vol.20 , pp. 2072-2079
    • Llovet, J.M.1    Hernandez-Gea, V.2
  • 9
    • 80054848246 scopus 로고    scopus 로고
    • Reduced risk of breast cancer recurrence in patients using ACE inhibitors, ARBs, and/or statins
    • Chae YK, Valsecchi ME, Kim J, Reduced risk of breast cancer recurrence in patients using ACE inhibitors, ARBs, and/or statins. Cancer Invest 2011; 29: 585–593.
    • (2011) Cancer Invest , vol.29 , pp. 585-593
    • Chae, Y.K.1    Valsecchi, M.E.2    Kim, J.3
  • 10
    • 84982946597 scopus 로고    scopus 로고
    • Increased tumor response to neoadjuvant therapy among rectal cancer patients taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers
    • Morris ZS, Saha S, Magnuson WJ, Increased tumor response to neoadjuvant therapy among rectal cancer patients taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. Cancer 2016; 122: 2487–2495.
    • (2016) Cancer , vol.122 , pp. 2487-2495
    • Morris, Z.S.1    Saha, S.2    Magnuson, W.J.3
  • 11
    • 80051889719 scopus 로고    scopus 로고
    • Angiotensin system inhibitors and outcome of sunitinib treatment in patients with metastatic renal cell carcinoma: a retrospective examination
    • Keizman D, Huang P, Eisenberger MA, Angiotensin system inhibitors and outcome of sunitinib treatment in patients with metastatic renal cell carcinoma: a retrospective examination. Eur J Cancer 2011; 47: 1955–1961.
    • (2011) Eur J Cancer , vol.47 , pp. 1955-1961
    • Keizman, D.1    Huang, P.2    Eisenberger, M.A.3
  • 12
    • 78650224339 scopus 로고    scopus 로고
    • Inhibition of renin–angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine
    • Nakai Y, Isayama H, Ijichi H, Inhibition of renin–angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine. Br J Cancer 2010; 103: 1644–1648.
    • (2010) Br J Cancer , vol.103 , pp. 1644-1648
    • Nakai, Y.1    Isayama, H.2    Ijichi, H.3
  • 13
    • 69049113864 scopus 로고    scopus 로고
    • Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy
    • Wilop S, von Hobe S, Crysandt M, Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy. J Cancer Res Clin Oncol 2009; 135: 1429–1435.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 1429-1435
    • Wilop, S.1    von Hobe, S.2    Crysandt, M.3
  • 14
    • 84938060465 scopus 로고    scopus 로고
    • Hypertension and angiotensin system inhibitors: impact on outcome in sunitinib-treated patients for metastatic renal cell carcinoma
    • Izzedine H, Derosa L, Le Teuff G, Hypertension and angiotensin system inhibitors: impact on outcome in sunitinib-treated patients for metastatic renal cell carcinoma. Ann Oncol 2015; 26: 1128–1133.
    • (2015) Ann Oncol , vol.26 , pp. 1128-1133
    • Izzedine, H.1    Derosa, L.2    Le Teuff, G.3
  • 15
    • 84939464030 scopus 로고    scopus 로고
    • Impact of renin–angiotensin system blockade on clinical outcome in glioblastoma
    • Januel E, Ursu R, Alkhafaji A, Impact of renin–angiotensin system blockade on clinical outcome in glioblastoma. Eur J Neurol 2015; 22: 1304–1309.
    • (2015) Eur J Neurol , vol.22 , pp. 1304-1309
    • Januel, E.1    Ursu, R.2    Alkhafaji, A.3
  • 16
    • 84994891094 scopus 로고    scopus 로고
    • Effect of angiotensin system inhibitors on survival in patients receiving chemotherapy for advanced non-small-cell lung cancer
    • Epub ahead of print 20 August 2016
    • Menter AR, Carroll NM, Sakoda LC, Effect of angiotensin system inhibitors on survival in patients receiving chemotherapy for advanced non-small-cell lung cancer. Clin Lung Cancer. Epub ahead of print 20 August 2016. DOI: 10.1016/j.cllc.2016.07.008.
    • Clin Lung Cancer
    • Menter, A.R.1    Carroll, N.M.2    Sakoda, L.C.3
  • 17
    • 84958909053 scopus 로고    scopus 로고
    • Angiotensin system inhibitors and survival in patients with metastatic renal cell carcinoma treated with VEGF-targeted therapy: a pooled secondary analysis of clinical trials
    • Sorich MJ, Kichenadasse G, Rowland A, Angiotensin system inhibitors and survival in patients with metastatic renal cell carcinoma treated with VEGF-targeted therapy: a pooled secondary analysis of clinical trials. Int J Cancer 2016; 138: 2293–2299.
    • (2016) Int J Cancer , vol.138 , pp. 2293-2299
    • Sorich, M.J.1    Kichenadasse, G.2    Rowland, A.3
  • 18
    • 84943595231 scopus 로고    scopus 로고
    • Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients
    • Facciorusso A, Del Prete V, Crucinio N, Angiotensin receptor blockers improve survival outcomes after radiofrequency ablation in hepatocarcinoma patients. J Gastroenterol Hepatol 2015; 30: 1643–1650.
    • (2015) J Gastroenterol Hepatol , vol.30 , pp. 1643-1650
    • Facciorusso, A.1    Del Prete, V.2    Crucinio, N.3
  • 19
    • 80053494651 scopus 로고    scopus 로고
    • Combination of branched-chain amino acids and angiotensin-converting enzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma: a randomized control trial
    • Yoshiji H, Noguchi R, Ikenaka Y, Combination of branched-chain amino acids and angiotensin-converting enzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma: a randomized control trial. Oncol Rep 2011; 26: 1547–1553.
    • (2011) Oncol Rep , vol.26 , pp. 1547-1553
    • Yoshiji, H.1    Noguchi, R.2    Ikenaka, Y.3
  • 20
    • 67649158636 scopus 로고    scopus 로고
    • Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma
    • Yoshiji H, Noguchi R, Toyohara M, Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma. J Hepatol 2009; 51: 315–321.
    • (2009) J Hepatol , vol.51 , pp. 315-321
    • Yoshiji, H.1    Noguchi, R.2    Toyohara, M.3
  • 21
    • 84919467172 scopus 로고    scopus 로고
    • Combination of sorafenib and angiotensin-II receptor blocker attenuates preneoplastic lesion development in a non-diabetic rat model of steatohepatitis
    • Yoshiji H, Noguchi R, Namisaki T, Combination of sorafenib and angiotensin-II receptor blocker attenuates preneoplastic lesion development in a non-diabetic rat model of steatohepatitis. J Gastroenterol 2014; 49: 1421–1429.
    • (2014) J Gastroenterol , vol.49 , pp. 1421-1429
    • Yoshiji, H.1    Noguchi, R.2    Namisaki, T.3
  • 22
    • 44449085884 scopus 로고    scopus 로고
    • Design and endpoints of clinical trials in hepatocellular carcinoma
    • Llovet JM, Di Bisceglie AM, Bruix J, Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst 2008; 100: 698–711.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 698-711
    • Llovet, J.M.1    Di Bisceglie, A.M.2    Bruix, J.3
  • 23
    • 77955304201 scopus 로고    scopus 로고
    • Renin–angiotensin–aldosterone inhibitors in the reduction of portal pressure: a systematic review and meta-analysis
    • Tandon P, Abraldes JG, Berzigotti A, Renin–angiotensin–aldosterone inhibitors in the reduction of portal pressure: a systematic review and meta-analysis. J Hepatol 2010; 53: 273–282.
    • (2010) J Hepatol , vol.53 , pp. 273-282
    • Tandon, P.1    Abraldes, J.G.2    Berzigotti, A.3
  • 24
    • 51849135397 scopus 로고    scopus 로고
    • The renin–angiotensin system and malignancy
    • Ager EI, Neo J, Christophi C. The renin–angiotensin system and malignancy. Carcinogenesis 2008; 29: 1675–1684.
    • (2008) Carcinogenesis , vol.29 , pp. 1675-1684
    • Ager, E.I.1    Neo, J.2    Christophi, C.3
  • 25
    • 77958502224 scopus 로고    scopus 로고
    • The renin–angiotensin system and cancer: old dog, new tricks
    • George AJ, Thomas WG, Hannan RD. The renin–angiotensin system and cancer: old dog, new tricks. Nat Rev Cancer 2010; 10: 745–759.
    • (2010) Nat Rev Cancer , vol.10 , pp. 745-759
    • George, A.J.1    Thomas, W.G.2    Hannan, R.D.3
  • 26
    • 83555174926 scopus 로고    scopus 로고
    • The effects of sorafenib on the portal hypertensive syndrome in patients with liver cirrhosis and hepatocellular carcinoma: a pilot study
    • Pinter M, Sieghart W, Reiberger T, The effects of sorafenib on the portal hypertensive syndrome in patients with liver cirrhosis and hepatocellular carcinoma: a pilot study. Aliment Pharmacol Ther 2012; 35: 83–91.
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 83-91
    • Pinter, M.1    Sieghart, W.2    Reiberger, T.3
  • 27
    • 84885129359 scopus 로고    scopus 로고
    • Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
    • Chauhan VP, Martin JD, Liu H, Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels. Nat Commun 2013; 4: 2516–2516.
    • (2013) Nat Commun , vol.4 , pp. 2516
    • Chauhan, V.P.1    Martin, J.D.2    Liu, H.3
  • 28
    • 0034120267 scopus 로고    scopus 로고
    • Angiotensin II induces contraction and proliferation of human hepatic stellate cells
    • Bataller R, Gines P, Nicolas JM, Angiotensin II induces contraction and proliferation of human hepatic stellate cells. Gastroenterology 2000; 118: 1149–1156.
    • (2000) Gastroenterology , vol.118 , pp. 1149-1156
    • Bataller, R.1    Gines, P.2    Nicolas, J.M.3
  • 30
    • 84876993950 scopus 로고    scopus 로고
    • Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers
    • Jain RK. Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers. J Clin Oncol 2013; 31: 2205–2218.
    • (2013) J Clin Oncol , vol.31 , pp. 2205-2218
    • Jain, R.K.1
  • 31
    • 0034802566 scopus 로고    scopus 로고
    • Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats
    • Yoshiji H, Kuriyama S, Yoshii J, Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats. Hepatology 2001; 34: 745–750.
    • (2001) Hepatology , vol.34 , pp. 745-750
    • Yoshiji, H.1    Kuriyama, S.2    Yoshii, J.3
  • 32
    • 84896732545 scopus 로고    scopus 로고
    • The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltration
    • Watt J, Kocher HM. The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltration. Oncoimmunology 2013; 2: e26788–e26788.
    • (2013) Oncoimmunology , vol.2 , pp. e26788
    • Watt, J.1    Kocher, H.M.2
  • 33
    • 84905103883 scopus 로고    scopus 로고
    • Fibroblast heterogeneity in the cancer wound
    • Ohlund D, Elyada E, Tuveson D. Fibroblast heterogeneity in the cancer wound. J Exp Med 2014; 211: 1503–1523.
    • (2014) J Exp Med , vol.211 , pp. 1503-1523
    • Ohlund, D.1    Elyada, E.2    Tuveson, D.3
  • 34
    • 84890281217 scopus 로고    scopus 로고
    • Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
    • Feig C, Jones JO, Kraman M, Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proc Natl Acad Sci USA 2013; 110: 20212–20217.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 20212-20217
    • Feig, C.1    Jones, J.O.2    Kraman, M.3
  • 35
    • 85016496640 scopus 로고    scopus 로고
    • Can targeting stroma pave the way to enhanced antitumor immunity and immunotherapy of solid tumors?
    • Pure E, Lo A. Can targeting stroma pave the way to enhanced antitumor immunity and immunotherapy of solid tumors? Cancer Immunol Res 2016; 4: 269–278.
    • (2016) Cancer Immunol Res , vol.4 , pp. 269-278
    • Pure, E.1    Lo, A.2
  • 36
    • 84904323068 scopus 로고    scopus 로고
    • The role of mechanical forces in tumor growth and therapy
    • Jain RK, Martin JD, Stylianopoulos T. The role of mechanical forces in tumor growth and therapy. Annu Rev Biomed Eng 2014; 16: 321–346.
    • (2014) Annu Rev Biomed Eng , vol.16 , pp. 321-346
    • Jain, R.K.1    Martin, J.D.2    Stylianopoulos, T.3
  • 37
    • 84912096468 scopus 로고    scopus 로고
    • Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia
    • Jain RK. Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. Cancer Cell 2014; 26: 605–622.
    • (2014) Cancer Cell , vol.26 , pp. 605-622
    • Jain, R.K.1
  • 38
    • 84904720194 scopus 로고    scopus 로고
    • Role of desmoplasia in cholangiocarcinoma and hepatocellular carcinoma
    • Lee JI, Campbell JS. Role of desmoplasia in cholangiocarcinoma and hepatocellular carcinoma. J Hepatol 2014; 61: 432–434.
    • (2014) J Hepatol , vol.61 , pp. 432-434
    • Lee, J.I.1    Campbell, J.S.2
  • 39
    • 84896492282 scopus 로고    scopus 로고
    • Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice
    • Chen Y, Huang Y, Reiberger T, Differential effects of sorafenib on liver versus tumor fibrosis mediated by stromal-derived factor 1 alpha/C-X-C receptor type 4 axis and myeloid differentiation antigen-positive myeloid cell infiltration in mice. Hepatology 2014; 59: 1435–1447.
    • (2014) Hepatology , vol.59 , pp. 1435-1447
    • Chen, Y.1    Huang, Y.2    Reiberger, T.3
  • 40
    • 77950608186 scopus 로고    scopus 로고
    • Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats
    • Moreno M, Gonzalo T, Kok RJ, Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology 2010; 51: 942–952.
    • (2010) Hepatology , vol.51 , pp. 942-952
    • Moreno, M.1    Gonzalo, T.2    Kok, R.J.3
  • 41
    • 0034961836 scopus 로고    scopus 로고
    • Angiotensin–converting enzyme inhibition attenuates the progression of rat hepatic fibrosis
    • Jonsson JR, Clouston AD, Ando Y, Angiotensin–converting enzyme inhibition attenuates the progression of rat hepatic fibrosis. Gastroenterology 2001; 121: 148–155.
    • (2001) Gastroenterology , vol.121 , pp. 148-155
    • Jonsson, J.R.1    Clouston, A.D.2    Ando, Y.3
  • 42
    • 0034849945 scopus 로고    scopus 로고
    • Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis
    • Paizis G, Gilbert RE, Cooper ME, Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis. J Hepatol 2001; 35: 376–385.
    • (2001) J Hepatol , vol.35 , pp. 376-385
    • Paizis, G.1    Gilbert, R.E.2    Cooper, M.E.3
  • 43
    • 0035991447 scopus 로고    scopus 로고
    • Inhibition of renin–angiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats
    • Yoshiji H, Yoshii J, Ikenaka Y, Inhibition of renin–angiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats. J Hepatol 2002; 37: 22–30.
    • (2002) J Hepatol , vol.37 , pp. 22-30
    • Yoshiji, H.1    Yoshii, J.2    Ikenaka, Y.3
  • 44
    • 64749115204 scopus 로고    scopus 로고
    • The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C
    • Corey KE, Shah N, Misdraji J, The effect of angiotensin-blocking agents on liver fibrosis in patients with hepatitis C. Liver Int 2009; 29: 748–753.
    • (2009) Liver Int , vol.29 , pp. 748-753
    • Corey, K.E.1    Shah, N.2    Misdraji, J.3
  • 45
    • 4544342831 scopus 로고    scopus 로고
    • Beneficial effect of angiotensin-blocking agents on graft fibrosis in hepatitis C recurrence after liver transplantation
    • Rimola A, Londono MC, Guevara G, Beneficial effect of angiotensin-blocking agents on graft fibrosis in hepatitis C recurrence after liver transplantation. Transplantation 2004; 78: 686–691.
    • (2004) Transplantation , vol.78 , pp. 686-691
    • Rimola, A.1    Londono, M.C.2    Guevara, G.3
  • 46
    • 18644369234 scopus 로고    scopus 로고
    • Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C
    • Terui Y, Saito T, Watanabe H, Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C. Hepatology 2002; 36: 1022–1022.
    • (2002) Hepatology , vol.36 , pp. 1022
    • Terui, Y.1    Saito, T.2    Watanabe, H.3
  • 47
    • 57349090407 scopus 로고    scopus 로고
    • Gene expression in fixed tissues and outcome in hepatocellular carcinoma
    • Hoshida Y, Villanueva A, Kobayashi M, Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 2008; 359: 1995–2004.
    • (2008) N Engl J Med , vol.359 , pp. 1995-2004
    • Hoshida, Y.1    Villanueva, A.2    Kobayashi, M.3
  • 48
    • 80055017402 scopus 로고    scopus 로고
    • Safety and efficacy of sorafenib in hepatocellular carcinoma: the impact of the Child-Pugh score
    • Hollebecque A, Cattan S, Romano O, Safety and efficacy of sorafenib in hepatocellular carcinoma: the impact of the Child-Pugh score. Aliment Pharmacol Ther 2011; 34: 1193–1201.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 1193-1201
    • Hollebecque, A.1    Cattan, S.2    Romano, O.3
  • 49
    • 80053217954 scopus 로고    scopus 로고
    • Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib
    • Pinter M, Sieghart W, Hucke F, Prognostic factors in patients with advanced hepatocellular carcinoma treated with sorafenib. Aliment Pharmacol Ther 2011; 34: 949–959.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 949-959
    • Pinter, M.1    Sieghart, W.2    Hucke, F.3
  • 50
    • 84927788483 scopus 로고    scopus 로고
    • Sorafenib therapy for hepatocellular carcinoma with extrahepatic spread: treatment outcome and prognostic factors
    • Sohn W, Paik YH, Cho JY, Sorafenib therapy for hepatocellular carcinoma with extrahepatic spread: treatment outcome and prognostic factors. J Hepatol 2015; 62: 1112–1121.
    • (2015) J Hepatol , vol.62 , pp. 1112-1121
    • Sohn, W.1    Paik, Y.H.2    Cho, J.Y.3
  • 51
    • 84880998463 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme and the tumor microenvironment: mechanisms beyond angiogenesis
    • Okwan-Duodu D, Landry J, Shen XZ, Angiotensin-converting enzyme and the tumor microenvironment: mechanisms beyond angiogenesis. Am J Physiol Regul Integr Comp Physiol 2013; 305: R205–R215.
    • (2013) Am J Physiol Regul Integr Comp Physiol , vol.305 , pp. R205-R215
    • Okwan-Duodu, D.1    Landry, J.2    Shen, X.Z.3
  • 52
    • 85047693609 scopus 로고    scopus 로고
    • Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth
    • Egami K, Murohara T, Shimada T, Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth. J Clini Invest 2003; 112: 67–75.
    • (2003) J Clini Invest , vol.112 , pp. 67-75
    • Egami, K.1    Murohara, T.2    Shimada, T.3
  • 53
    • 13844255555 scopus 로고    scopus 로고
    • Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth
    • Fujita M, Hayashi I, Yamashina S, Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth. Carcinogenesis 2005; 26: 271–279.
    • (2005) Carcinogenesis , vol.26 , pp. 271-279
    • Fujita, M.1    Hayashi, I.2    Yamashina, S.3
  • 54
    • 59049088369 scopus 로고    scopus 로고
    • Blockade of an angiotensin type I receptor enhances effects of radiation on tumor growth and tumor-associated angiogenesis by reducing vascular endothelial growth factor expression
    • Ohnuma Y, Toda M, Fujita M, Blockade of an angiotensin type I receptor enhances effects of radiation on tumor growth and tumor-associated angiogenesis by reducing vascular endothelial growth factor expression. Biomed Pharmacother 2009; 63: 136–145.
    • (2009) Biomed Pharmacother , vol.63 , pp. 136-145
    • Ohnuma, Y.1    Toda, M.2    Fujita, M.3
  • 55
    • 77951891161 scopus 로고    scopus 로고
    • Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma
    • Otake AH, Mattar AL, Freitas HC, Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma. Cancer Chemother Pharmacol 2010; 66: 79–87.
    • (2010) Cancer Chemother Pharmacol , vol.66 , pp. 79-87
    • Otake, A.H.1    Mattar, A.L.2    Freitas, H.C.3
  • 56
    • 0347995046 scopus 로고    scopus 로고
    • Combination of interferon-beta and the angiotensin-converting enzyme inhibitor, perindopril, attenuates murine hepatocellular carcinoma development and angiogenesis
    • Noguchi R, Yoshiji H, Kuriyama S, Combination of interferon-beta and the angiotensin-converting enzyme inhibitor, perindopril, attenuates murine hepatocellular carcinoma development and angiogenesis. Clin Cancer Res 2003; 9: 6038–6045.
    • (2003) Clin Cancer Res , vol.9 , pp. 6038-6045
    • Noguchi, R.1    Yoshiji, H.2    Kuriyama, S.3
  • 57
    • 15044356179 scopus 로고    scopus 로고
    • Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in mice
    • Yoshiji H, Noguchi R, Kuriyama S, Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in mice. Oncol Rep 2005; 13: 491–495.
    • (2005) Oncol Rep , vol.13 , pp. 491-495
    • Yoshiji, H.1    Noguchi, R.2    Kuriyama, S.3
  • 58
    • 84886514953 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor antagonist prevents hepatic carcinoma in rats with nonalcoholic steatohepatitis
    • Tamaki Y, Nakade Y, Yamauchi T, Angiotensin II type 1 receptor antagonist prevents hepatic carcinoma in rats with nonalcoholic steatohepatitis. J Gastroenterol 2013; 48: 491–503.
    • (2013) J Gastroenterol , vol.48 , pp. 491-503
    • Tamaki, Y.1    Nakade, Y.2    Yamauchi, T.3
  • 59
    • 33947720545 scopus 로고    scopus 로고
    • Synergistic inhibition of hepatocellular carcinoma growth and hepatocarcinogenesis by combination of 5–fluorouracil and angiotensin-converting enzyme inhibitor via anti-angiogenic activities
    • Yanase K, Yoshiji H, Ikenaka Y, Synergistic inhibition of hepatocellular carcinoma growth and hepatocarcinogenesis by combination of 5–fluorouracil and angiotensin-converting enzyme inhibitor via anti-angiogenic activities. Oncol Rep 2007; 17: 441–446.
    • (2007) Oncol Rep , vol.17 , pp. 441-446
    • Yanase, K.1    Yoshiji, H.2    Ikenaka, Y.3
  • 60
    • 84893791372 scopus 로고    scopus 로고
    • Targeting different angiogenic pathways with combination of curcumin, leflunomide and perindopril inhibits diethylnitrosamine-induced hepatocellular carcinoma in mice
    • Nasr M, Selima E, Hamed O, Targeting different angiogenic pathways with combination of curcumin, leflunomide and perindopril inhibits diethylnitrosamine-induced hepatocellular carcinoma in mice. Eur J Pharmacol 2014; 723: 267–275.
    • (2014) Eur J Pharmacol , vol.723 , pp. 267-275
    • Nasr, M.1    Selima, E.2    Hamed, O.3
  • 61
    • 0034907881 scopus 로고    scopus 로고
    • The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor
    • Yoshiji H, Kuriyama S, Kawata M, The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor. Clin Cancer Res 2001; 7: 1073–1078.
    • (2001) Clin Cancer Res , vol.7 , pp. 1073-1078
    • Yoshiji, H.1    Kuriyama, S.2    Kawata, M.3
  • 62
    • 20144389070 scopus 로고    scopus 로고
    • Combination of vitamin K2 and the angiotensin-converting enzyme inhibitor, perindopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppression
    • Yoshiji H, Kuriyama S, Noguchi R, Combination of vitamin K2 and the angiotensin-converting enzyme inhibitor, perindopril, attenuates the liver enzyme-altered preneoplastic lesions in rats via angiogenesis suppression. J Hepatol 2005; 42: 687–693.
    • (2005) J Hepatol , vol.42 , pp. 687-693
    • Yoshiji, H.1    Kuriyama, S.2    Noguchi, R.3
  • 63
    • 33644877833 scopus 로고    scopus 로고
    • Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities
    • Yoshiji H, Kuriyama S, Noguchi R, Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities. Oncol Rep 2006; 15: 155–159.
    • (2006) Oncol Rep , vol.15 , pp. 155-159
    • Yoshiji, H.1    Kuriyama, S.2    Noguchi, R.3
  • 64
    • 77953324172 scopus 로고    scopus 로고
    • Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats
    • Yoshiji H, Noguchi R, Kaji K, Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats. J Gastroenterol 2010; 45: 443–450.
    • (2010) J Gastroenterol , vol.45 , pp. 443-450
    • Yoshiji, H.1    Noguchi, R.2    Kaji, K.3
  • 65
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57–70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 66
    • 59349121044 scopus 로고    scopus 로고
    • Angiogenesis in liver disease
    • Fernandez M, Semela D, Bruix J, Angiogenesis in liver disease. J Hepatol 2009; 50: 604–620.
    • (2009) J Hepatol , vol.50 , pp. 604-620
    • Fernandez, M.1    Semela, D.2    Bruix, J.3
  • 67
    • 0037903052 scopus 로고    scopus 로고
    • Portal pressure response to losartan compared with propranolol in patients with cirrhosis
    • De BK, Bandyopadhyay K, Das TK, Portal pressure response to losartan compared with propranolol in patients with cirrhosis. Am J Gastroenterol 2003; 98: 1371–1376.
    • (2003) Am J Gastroenterol , vol.98 , pp. 1371-1376
    • De, B.K.1    Bandyopadhyay, K.2    Das, T.K.3
  • 68
    • 34247633516 scopus 로고    scopus 로고
    • AT1 receptor antagonist Candesartan in selected cirrhotic patients: effect on portal pressure and liver fibrosis markers
    • Debernardi-Venon W, Martini S, Biasi F, AT1 receptor antagonist Candesartan in selected cirrhotic patients: effect on portal pressure and liver fibrosis markers. J Hepatol 2007; 46: 1026–1033.
    • (2007) J Hepatol , vol.46 , pp. 1026-1033
    • Debernardi-Venon, W.1    Martini, S.2    Biasi, F.3
  • 69
    • 0035433365 scopus 로고    scopus 로고
    • Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis
    • Gonzalez-Abraldes J, Albillos A, Banares R, Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis. Gastroenterology 2001; 121: 382–388.
    • (2001) Gastroenterology , vol.121 , pp. 382-388
    • Gonzalez-Abraldes, J.1    Albillos, A.2    Banares, R.3
  • 70
    • 0032988091 scopus 로고    scopus 로고
    • Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis
    • Schneider AW, Kalk JF, Klein CP. Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis. Hepatology 1999; 29: 334–339.
    • (1999) Hepatology , vol.29 , pp. 334-339
    • Schneider, A.W.1    Kalk, J.F.2    Klein, C.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.