-
1
-
-
0037648348
-
The case for early detection
-
Etzioni, R. et al. The case for early detection. Nat. Rev. Cancer 3, 243-252 (2003).
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 243-252
-
-
Etzioni, R.1
-
3
-
-
84869024683
-
Survival afer liver resection in metastatic colorectal cancer: Review and meta-analysis of prognostic factors
-
Kanas, G. P. et al. Survival afer liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors. Clin. Epidemiol. 4, 283-301 (2012).
-
(2012)
Clin. Epidemiol.
, vol.4
, pp. 283-301
-
-
Kanas, G.P.1
-
4
-
-
0036498788
-
Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: A meta-analysis
-
Bristow, R. E., Tomacruz, R. S., Armstrong, D. K., Trimble, E. L. & Montz, F. J. Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis. J. Clin. Oncol. 20, 1248-1259 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1248-1259
-
-
Bristow, R.E.1
Tomacruz, R.S.2
Armstrong, D.K.3
Trimble, E.L.4
Montz, F.J.5
-
5
-
-
84896390476
-
The prognostic signifcance of pre- and post-treatment CA-125 in grade 1 serous ovarian carcinoma: A gynecologic Oncology Group study
-
Fader, A. N. et al. The prognostic signifcance of pre- and post-treatment CA-125 in grade 1 serous ovarian carcinoma: a gynecologic Oncology Group study. Gynecol. Oncol. 132, 560-565 (2014).
-
(2014)
Gynecol. Oncol.
, vol.132
, pp. 560-565
-
-
Fader, A.N.1
-
6
-
-
84884183059
-
Long-term mortality afer screening for colorectal cancer
-
Shaukat, A. et al. Long-term mortality afer screening for colorectal cancer. N. Engl. J. Med. 369, 1106-1114 (2013).
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 1106-1114
-
-
Shaukat, A.1
-
7
-
-
50549102118
-
New technologies for human cancer imaging
-
Frangioni, J. V. New technologies for human cancer imaging. J. Clin. Oncol. 26, 4012-4021 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 4012-4021
-
-
Frangioni, J.V.1
-
8
-
-
81455150067
-
Mathematical model identifies blood biomarker-based early cancer detection strategies and limitations
-
Hori, S. S. & Gambhir, S. S. Mathematical model identifies blood biomarker-based early cancer detection strategies and limitations. Sci. Transl. Med. 3, 109ra116 (2011).
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 109ra116
-
-
Hori, S.S.1
Gambhir, S.S.2
-
10
-
-
84872176550
-
Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease
-
Kwong, G. A. et al. Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease. Nat. Biotechnol. 31, 63-70 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 63-70
-
-
Kwong, G.A.1
-
11
-
-
84896277174
-
Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfuidics
-
Warren, A. D., Kwong, G. A., Wood, D. K., Lin, K. Y. & Bhatia, S. N. Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfuidics. Proc. Natl Acad. Sci. USA 111, 3671-3676 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 3671-3676
-
-
Warren, A.D.1
Kwong, G.A.2
Wood, D.K.3
Lin, K.Y.4
Bhatia, S.N.5
-
12
-
-
0034651996
-
Unraveling the role of proteases in cancer
-
Koblinski, J. E., Ahram, M. & Sloane, B. F. Unraveling the role of proteases in cancer. Clin. Chim. Acta 291, 113-135 (2000).
-
(2000)
Clin. Chim. Acta
, vol.291
, pp. 113-135
-
-
Koblinski, J.E.1
Ahram, M.2
Sloane, B.F.3
-
13
-
-
84944088971
-
Mathematical framework for activity-based cancer biomarkers
-
Kwong, G. A. et al. Mathematical framework for activity-based cancer biomarkers. Proc. Natl Acad. Sci. USA 112, 12627-12632 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 12627-12632
-
-
Kwong, G.A.1
-
14
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock, K., Plaks, V. & Werb, Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141, 52-67 (2010).
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
15
-
-
84893352943
-
Gelatinase B/MMP-9 in tumour pathogenesis and progression
-
Farina, A. R. & Mackay, A. R. Gelatinase B/MMP-9 in tumour pathogenesis and progression. Cancers 6, 240-296 (2014).
-
(2014)
Cancers
, vol.6
, pp. 240-296
-
-
Farina, A.R.1
Mackay, A.R.2
-
16
-
-
40749099079
-
Prognostic signifcance of MMP-9 and TIMP-1 serum and tissue expression in breast cancer
-
Wu, Z.-S. et al. Prognostic signifcance of MMP-9 and TIMP-1 serum and tissue expression in breast cancer. Int. J. Cancer 122, 2050-2056 (2008).
-
(2008)
Int. J. Cancer
, vol.122
, pp. 2050-2056
-
-
Wu, Z.-S.1
-
17
-
-
55549134994
-
Kinetics of enzyme attack on substrates covalently attached to solid surfaces: Infuence of spacer chain length, immobilized substrate surface concentration and surface charge
-
Deere, J. et al. Kinetics of enzyme attack on substrates covalently attached to solid surfaces: infuence of spacer chain length, immobilized substrate surface concentration and surface charge. Langmuir 24, 11762-11769 (2008).
-
(2008)
Langmuir
, vol.24
, pp. 11762-11769
-
-
Deere, J.1
-
18
-
-
0029758751
-
Human matrix metalloproteinase specifcity studies using collagen sequence-based synthetic peptides
-
Nagase, H. & Fields, G. B. Human matrix metalloproteinase specifcity studies using collagen sequence-based synthetic peptides. Peptide Sci. 40, 399-416 (1996).
-
(1996)
Peptide Sci.
, vol.40
, pp. 399-416
-
-
Nagase, H.1
Fields, G.B.2
-
19
-
-
79953746083
-
Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities
-
Miller, M. A. et al. Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities. Integr. Biol. 3, 422-438 (2011).
-
(2011)
Integr. Biol.
, vol.3
, pp. 422-438
-
-
Miller, M.A.1
-
20
-
-
84954509620
-
A mouse-human phase 1 co-clinical trial of a protease-activated fuorescent probe for imaging cancer
-
Whitley, M. J. et al. A mouse-human phase 1 co-clinical trial of a protease-activated fuorescent probe for imaging cancer. Sci. Transl. Med. 8, 320ra4 (2016).
-
(2016)
Sci. Transl. Med.
, vol.8
, pp. 320ra4
-
-
Whitley, M.J.1
-
21
-
-
84886423341
-
Tumor-specifc activation of an EGFR-targeting probody enhances therapeutic index
-
Desnoyers, L. R. et al. Tumor-specifc activation of an EGFR-targeting probody enhances therapeutic index. Sci. Transl. Med. 5, 207ra144 (2013).
-
(2013)
Sci. Transl. Med.
, vol.5
, pp. 207ra144
-
-
Desnoyers, L.R.1
-
22
-
-
84947811317
-
Predicting therapeutic nanomedicine efcacy using a companion magnetic resonance imaging nanoparticle
-
Miller, M. A. et al. Predicting therapeutic nanomedicine efcacy using a companion magnetic resonance imaging nanoparticle. Sci. Transl. Med. 7, 314ra183 (2015).
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 314ra183
-
-
Miller, M.A.1
-
23
-
-
84896699451
-
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
-
Bertrand, N., Wu, J., Xu, X., Kamaly, N. & Farokhzad, O. C. Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv. Drug Deliv. Rev. 66, 2-25 (2014).
-
(2014)
Adv. Drug Deliv. Rev.
, vol.66
, pp. 2-25
-
-
Bertrand, N.1
Wu, J.2
Xu, X.3
Kamaly, N.4
Farokhzad, O.C.5
-
24
-
-
85016350463
-
Analysis of nanoparticle delivery to tumours
-
Wilhelm, S. et al. Analysis of nanoparticle delivery to tumours. Nat. Rev. Mater. 1, 16014 (2016).
-
(2016)
Nat. Rev. Mater.
, vol.1
, pp. 16014
-
-
Wilhelm, S.1
-
25
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
Davis, M. E. et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 464, 1067-1070 (2010).
-
(2010)
Nature
, vol.464
, pp. 1067-1070
-
-
Davis, M.E.1
-
26
-
-
84858665432
-
Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a diferentiated pharmacological profle
-
Hrkach, J. et al. Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a diferentiated pharmacological profle. Sci. Transl. Med. 4, 128ra39 (2012).
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 128ra39
-
-
Hrkach, J.1
-
27
-
-
0036488496
-
Specialization of tumour vasculature
-
Ruoslahti, E. Specialization of tumour vasculature. Nat. Rev. Cancer 2, 83-90 (2002).
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 83-90
-
-
Ruoslahti, E.1
-
28
-
-
77949762340
-
Targeting of drugs and nanoparticles to tumors
-
Ruoslahti, E. & Bhatia, S. N. & Sailor, M. J. Targeting of drugs and nanoparticles to tumors. J. Cell Biol. 188, 759-768 (2010).
-
(2010)
J. Cell Biol.
, vol.188
, pp. 759-768
-
-
Ruoslahti, E.1
Bhatia, S.N.2
Sailor, M.J.3
-
29
-
-
84915809304
-
Drug-induced amplifcation of nanoparticle targeting to tumors
-
Lin, K. Y., Kwon, E. J., Lo, J. H. & Bhatia, S. N. Drug-induced amplifcation of nanoparticle targeting to tumors. Nano Today 9, 550-559 (2014).
-
(2014)
Nano Today
, vol.9
, pp. 550-559
-
-
Lin, K.Y.1
Kwon, E.J.2
Lo, J.H.3
Bhatia, S.N.4
-
30
-
-
84930654052
-
An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability
-
Pang, H.-B. et al. An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability. Nat. Commun. 5, 4904 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 4904
-
-
Pang, H.-B.1
-
31
-
-
52049123781
-
Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma
-
Fogal, V., Zhang, L., Krajewski, S. & Ruoslahti, E. Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma. Cancer Res. 68, 7210-7218 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 7210-7218
-
-
Fogal, V.1
Zhang, L.2
Krajewski, S.3
Ruoslahti, E.4
-
32
-
-
79960414991
-
Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9
-
Dufour, A. et al. Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res. 71, 4977-4988 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 4977-4988
-
-
Dufour, A.1
-
33
-
-
0023931167
-
An initial analysis of preoperative serum CA 125 levels in patients with early stage ovarian carcinoma
-
Zurawski, V. R. et al. An initial analysis of preoperative serum CA 125 levels in patients with early stage ovarian carcinoma. Gynecol. Oncol. 30, 7-14 (1988).
-
(1988)
Gynecol. Oncol.
, vol.30
, pp. 7-14
-
-
Zurawski, V.R.1
-
34
-
-
84867795473
-
Identifcation and characterization of receptor-specifc peptides for siRNA delivery
-
Ren, Y., Hauert, S., Lo, J. H. & Bhatia, S. N. Identifcation and characterization of receptor-specifc peptides for siRNA delivery. ACS Nano 6, 8620-8631 (2012).
-
(2012)
ACS Nano
, vol.6
, pp. 8620-8631
-
-
Ren, Y.1
Hauert, S.2
Lo, J.H.3
Bhatia, S.N.4
-
35
-
-
16844374909
-
Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
-
Drapkin, R. et al. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res. 65, 2162-2169 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 2162-2169
-
-
Drapkin, R.1
-
36
-
-
77957375963
-
AXL is an essential factor and therapeutic target for metastatic ovarian cancer
-
Rankin, E. B. et al. AXL is an essential factor and therapeutic target for metastatic ovarian cancer. Cancer Res. 70, 7570-7579 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 7570-7579
-
-
Rankin, E.B.1
-
37
-
-
0035913613
-
Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells
-
Alper, Ö. et al. Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells. J. Natl Cancer Inst. 93, 1375-1384 (2001).
-
(2001)
J. Natl Cancer Inst.
, vol.93
, pp. 1375-1384
-
-
Alper, Ö.1
-
38
-
-
68049122014
-
The preclinical natural history of serous ovarian cancer: Defining the target for early detection
-
Brown, P. O. & Palmer, C. The preclinical natural history of serous ovarian cancer: defining the target for early detection. PLoS Med. 6, e1000114 (2009).
-
(2009)
PLoS Med.
, vol.6
, pp. e1000114
-
-
Brown, P.O.1
Palmer, C.2
-
39
-
-
70749103751
-
Tissue-penetrating delivery of compounds and nanoparticles into tumors
-
Sugahara, K. N. et al. Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell 16, 510-520 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 510-520
-
-
Sugahara, K.N.1
-
40
-
-
72949119124
-
Integrins in cancer: Biological implications and therapeutic opportunities
-
Desgrosellier, J. S. & Cheresh, D. A. Integrins in cancer: biological implications and therapeutic opportunities. Nat. Rev. Cancer 10, 9-22 (2010).
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
41
-
-
1542359063
-
Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer
-
Yao, M., Lam, E. C., Kelly, C. R., Zhou, W. & Wolfe, M. M. Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer. Br. J. Cancer 90, 712-719 (2004).
-
(2004)
Br. J. Cancer
, vol.90
, pp. 712-719
-
-
Yao, M.1
Lam, E.C.2
Kelly, C.R.3
Zhou, W.4
Wolfe, M.M.5
-
42
-
-
85027954865
-
Update of human and mouse matrix metalloproteinase families
-
Jackson, B. C., Nebert, D. W. & Vasiliou, V. Update of human and mouse matrix metalloproteinase families. Hum. Genomics 4, 194-201 (2010).
-
(2010)
Hum. Genomics
, vol.4
, pp. 194-201
-
-
Jackson, B.C.1
Nebert, D.W.2
Vasiliou, V.3
-
43
-
-
84902181290
-
Activity-based profiling of proteases
-
Sanman, L. E. & Bogyo, M. Activity-based profiling of proteases. Annu. Rev. Biochem. 83, 249-273 (2014).
-
(2014)
Annu. Rev. Biochem.
, vol.83
, pp. 249-273
-
-
Sanman, L.E.1
Bogyo, M.2
-
44
-
-
84979862414
-
Labeling of active proteases in fresh-frozen tissues by topical application of quenched activity-based probes
-
Withana, N. P. et al. Labeling of active proteases in fresh-frozen tissues by topical application of quenched activity-based probes. Nat. Protoc. 11, 184-191 (2016).
-
(2016)
Nat. Protoc.
, vol.11
, pp. 184-191
-
-
Withana, N.P.1
-
45
-
-
77952901022
-
Coadministration of a tumor-penetrating peptide enhances the efcacy of cancer drugs
-
Sugahara, K. N. et al. Coadministration of a tumor-penetrating peptide enhances the efcacy of cancer drugs. Science 328, 1031-1035 (2010).
-
(2010)
Science
, vol.328
, pp. 1031-1035
-
-
Sugahara, K.N.1
-
46
-
-
79952280663
-
HE4 and CA125 as a diagnostic test in ovarian cancer: Prospective validation of the Risk of Ovarian Malignancy Algorithm
-
Van Gorp, T. et al. HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm. Br. J. Cancer 104, 863-870 (2011).
-
(2011)
Br. J. Cancer
, vol.104
, pp. 863-870
-
-
Van Gorp, T.1
-
47
-
-
79952036664
-
Contribution of power Doppler blood fow mapping to gray-scale ultrasound for predicting malignancy of adnexal masses in symptomatic and asymptomatic women
-
Alcázar, J. L., Guerriero, S., Laparte, C, Ajossa, S. & Jurado, M. Contribution of power Doppler blood fow mapping to gray-scale ultrasound for predicting malignancy of adnexal masses in symptomatic and asymptomatic women. Eur. J. Obstet. Gynecol Reprod. Biol 155, 99-105 (2011).
-
(2011)
Eur. J. Obstet. Gynecol Reprod. Biol
, vol.155
, pp. 99-105
-
-
Alcázar, J.L.1
Guerriero, S.2
Laparte Ajossa C, S.3
Jurado, M.4
-
48
-
-
63149196010
-
Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting.
-
Park, J.-H. et al Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting. Small 5, 694-700 (2009).
-
(2009)
Small
, vol.5
, pp. 694-700
-
-
Park, J.-H.1
|