메뉴 건너뛰기




Volumn 7, Issue 1, 2017, Pages

Epicutaneous allergen application preferentially boosts specific T cell responses in sensitized patients

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CYTOKINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G;

EID: 85029524598     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-10278-1     Document Type: Article
Times cited : (19)

References (30)
  • 1
    • 33750504243 scopus 로고    scopus 로고
    • EAACI/GA2LEN position paper: Present status of the atopy patch test
    • Turjanmaa, K., et al. EAACI/GA2LEN position paper: Present status of the atopy patch test. Allergy 61, 1377-84 (2006).
    • (2006) Allergy , vol.61 , pp. 1377-1384
    • Turjanmaa, K.1
  • 2
    • 76349094087 scopus 로고    scopus 로고
    • Developments in allergen-specific immunotherapy: From allergen extracts to allergy vaccines bypassing allergen-specific immunoglobulin E and T cell reactivity
    • Focke, M., Swoboda, I., Marth, K., Valenta, R. Developments in allergen-specific immunotherapy: From allergen extracts to allergy vaccines bypassing allergen-specific immunoglobulin E and T cell reactivity. Clin Exp Allergy 40, 385-97 (2010).
    • (2010) Clin Exp Allergy , vol.40 , pp. 385-397
    • Focke, M.1    Swoboda, I.2    Marth, K.3    Valenta, R.4
  • 3
    • 0033591638 scopus 로고    scopus 로고
    • Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions
    • Haselden, B. M., Kay, A. B., Larché, M. Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions. J Exp Med 189, 1885-94 (1999).
    • (1999) J Exp Med , vol.189 , pp. 1885-1894
    • Haselden, B.M.1    Kay, A.B.2    Larché, M.3
  • 4
    • 46849121475 scopus 로고    scopus 로고
    • Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives
    • Purohit, A., et al. Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives. Clin Exp Allergy 38, 1514-25 (2008).
    • (2008) Clin Exp Allergy , vol.38 , pp. 1514-1525
    • Purohit, A.1
  • 5
    • 38949213679 scopus 로고    scopus 로고
    • Non-IgE-mediated chronic allergic skin inflammation revealed with rBet v 1 fragments
    • Campana, R., et al. Non-IgE-mediated chronic allergic skin inflammation revealed with rBet v 1 fragments. J Allergy Clin Immunol 121, 528-30 (2008).
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 528-530
    • Campana, R.1
  • 6
    • 84957962861 scopus 로고    scopus 로고
    • Frequent occurrence of T cell-mediated late reactions revealed by atopy patch testing with hypoallergenic rBet v 1 fragments
    • Campana, R., et al. Frequent occurrence of T cell-mediated late reactions revealed by atopy patch testing with hypoallergenic rBet v 1 fragments. J Allergy Clin Immunol 137, 601-09 (2016).
    • (2016) J Allergy Clin Immunol , vol.137 , pp. 601-609
    • Campana, R.1
  • 7
    • 33846239232 scopus 로고    scopus 로고
    • Antigens drive memory IgE responses in human allergy via the nasal mucosa
    • Niederberger, V., et al. Antigens drive memory IgE responses in human allergy via the nasal mucosa. Int Arch Allergy Immunol 142, 133-44 (2007).
    • (2007) Int Arch Allergy Immunol , vol.142 , pp. 133-144
    • Niederberger, V.1
  • 8
    • 78649828969 scopus 로고    scopus 로고
    • Nasal application of rBet v 1 or non-IgE-reactive T-cell epitope-containing rBet v 1 fragments has different effects on systemic allergen-specific antibody responses
    • Egger, C., Horak, F., Vrtala, S., Valenta, R., Niederberger, V. Nasal application of rBet v 1 or non-IgE-reactive T-cell epitope-containing rBet v 1 fragments has different effects on systemic allergen-specific antibody responses. J Allergy Clin Immunol 126, 1312-15 (2010).
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 1312-1315
    • Egger, C.1    Horak, F.2    Vrtala, S.3    Valenta, R.4    Niederberger, V.5
  • 9
    • 0030937231 scopus 로고    scopus 로고
    • Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: Candidates for a novel form of specific immunotherapy
    • Vrtala, S., et al. Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: Candidates for a novel form of specific immunotherapy. J Clin Invest 99, 1673-81 (1997).
    • (1997) J Clin Invest , vol.99 , pp. 1673-1681
    • Vrtala, S.1
  • 10
    • 0025368379 scopus 로고
    • Comparion of diversity and function of house dust mite-specific T lymphocyte clones from atopic and non-atopic donors
    • Wierenga, E. A., Snoek, M., Bos, J. D., Jansen, H. M., Kapsenberg, M. L. Comparion of diversity and function of house dust mite-specific T lymphocyte clones from atopic and non-atopic donors. Eur J Immunol 20, 1519-26 (1990).
    • (1990) Eur J Immunol , vol.20 , pp. 1519-1526
    • Wierenga, E.A.1    Snoek, M.2    Bos, J.D.3    Jansen, H.M.4    Kapsenberg, M.L.5
  • 11
    • 0027324603 scopus 로고
    • T cell epitope specificity in human allergic and nonallergic subjects to bee venom phospholipase A2
    • Carballido, J. M., et al. T cell epitope specificity in human allergic and nonallergic subjects to bee venom phospholipase A2. J Immunol 150, 3582-91 (1993).
    • (1993) J Immunol , vol.150 , pp. 3582-3591
    • Carballido, J.M.1
  • 12
    • 0028873098 scopus 로고
    • Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients
    • Ebner, C., et al. Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients. J Immunol 154, 1932-40 (1995).
    • (1995) J Immunol , vol.154 , pp. 1932-1940
    • Ebner, C.1
  • 13
    • 44449145067 scopus 로고    scopus 로고
    • Assessment of Bet v 1-specific CD4+T cell responses in allergic and nonallergic individuals using MHC class II peptides tetramers
    • Van Overtvelt, L., et al. Assessment of Bet v 1-specific CD4+T cell responses in allergic and nonallergic individuals using MHC class II peptides tetramers. J Immunol 180, 4514-22 (2008).
    • (2008) J Immunol , vol.180 , pp. 4514-4522
    • Van Overtvelt, L.1
  • 14
    • 84979243112 scopus 로고    scopus 로고
    • Specific IgE and IgG measured by MeDALL allergen-chip depend on allergen and route of exposure: The EGEA study
    • Siroux, V., et al. Specific IgE and IgG measured by MeDALL allergen-chip depend on allergen and route of exposure: The EGEA study. J Allergy Clin Immunol 139, 643-54 (2017).
    • (2017) J Allergy Clin Immunol , vol.139 , pp. 643-654
    • Siroux, V.1
  • 15
    • 84990061237 scopus 로고    scopus 로고
    • Heat-labile Escherichia coli toxin enhances the induction of allergen-specific IgG antibodies in epicutaneous patch vaccination
    • Cabauatan, C. R., et al. Heat-labile Escherichia coli toxin enhances the induction of allergen-specific IgG antibodies in epicutaneous patch vaccination. Allergy 72, 164-68 (2017).
    • (2017) Allergy , vol.72 , pp. 164-168
    • Cabauatan, C.R.1
  • 16
    • 0033968962 scopus 로고    scopus 로고
    • Sensitization to inhaled antigen by intratracheal instillation of dendritic cells
    • Lambrecht, B. N., Peleman, R. A., Bullock, G. R., Pauwels, R. A. Sensitization to inhaled antigen by intratracheal instillation of dendritic cells. Clin Exp Allergy 30, 214-24 (2000).
    • (2000) Clin Exp Allergy , vol.30 , pp. 214-224
    • Lambrecht, B.N.1    Peleman, R.A.2    Bullock, G.R.3    Pauwels, R.A.4
  • 17
    • 0037661991 scopus 로고    scopus 로고
    • Characterization of dendritic cells from human oral mucosa: A new Langerhans' cell type with high constitutive FcepsilonRI expression
    • Allam, J. P., et al. Characterization of dendritic cells from human oral mucosa: A new Langerhans' cell type with high constitutive FcepsilonRI expression. J Allergy Clin Immunol 112, 141-48 (2003).
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 141-148
    • Allam, J.P.1
  • 18
    • 77956383005 scopus 로고    scopus 로고
    • Phl p 5 resorption in human oral mucosa leads to dose-dependent and time-dependent allergen binding by oral mucosal Langerhans cells, attenuates their maturation, and enhances their migratory and TGF-beta1 and IL-10-producing properties
    • Allam, J. P., et al. Phl p 5 resorption in human oral mucosa leads to dose-dependent and time-dependent allergen binding by oral mucosal Langerhans cells, attenuates their maturation, and enhances their migratory and TGF-beta1 and IL-10-producing properties. J Allergy Clin Immunol 126, 638-45 (2010).
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 638-645
    • Allam, J.P.1
  • 19
    • 84901786828 scopus 로고    scopus 로고
    • Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: A pilot study
    • Allam, J. P., et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: A pilot study. J Allergy Clin Immunol 133, 1757-59 (2014).
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 1757-1759
    • Allam, J.P.1
  • 20
    • 84923633972 scopus 로고    scopus 로고
    • Effects of nasal corticosteroids on boosts of systemic allergen-specific IgE production induced by nasal allergen exposure
    • Egger, C., et al. Effects of nasal corticosteroids on boosts of systemic allergen-specific IgE production induced by nasal allergen exposure. PLoS One 10, e0114991 (2015).
    • (2015) PLoS One , vol.10 , pp. e0114991
    • Egger, C.1
  • 21
    • 0034108370 scopus 로고    scopus 로고
    • Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4
    • Herrick, C. A., MacLeod, H., Glusac, E., Tigelaar, R. E., Bottomly, K. Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4. J Clin Invest 105, 765-75 (2000).
    • (2000) J Clin Invest , vol.105 , pp. 765-775
    • Herrick, C.A.1    MacLeod, H.2    Glusac, E.3    Tigelaar, R.E.4    Bottomly, K.5
  • 22
    • 84908636834 scopus 로고    scopus 로고
    • Skin exposure promotes a Th2-dependent sensitization to peanut allergens
    • Tordesillas, L., et al. Skin exposure promotes a Th2-dependent sensitization to peanut allergens. J Clin Invest 124, 4965-75 (2014).
    • (2014) J Clin Invest , vol.124 , pp. 4965-4975
    • Tordesillas, L.1
  • 23
    • 0032523018 scopus 로고    scopus 로고
    • Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice
    • Spergel, J. M., et al. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest 101, 1614-22 (1998).
    • (1998) J Clin Invest , vol.101 , pp. 1614-1622
    • Spergel, J.M.1
  • 24
    • 24144463721 scopus 로고    scopus 로고
    • Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice
    • Akei, H. S., Mishra, A., Blanchard, C., Rothenberg, M. E. Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice. Gastroenterology 129, 985-94 (2005).
    • (2005) Gastroenterology , vol.129 , pp. 985-994
    • Akei, H.S.1    Mishra, A.2    Blanchard, C.3    Rothenberg, M.E.4
  • 25
    • 79956201500 scopus 로고    scopus 로고
    • Epicutaneous immunotherapy results in rapid allergen uptake by dendritic cells through intact skin and downregulates the allergen-specific response in sensitized mice
    • Dioszeghy, V., et al. Epicutaneous immunotherapy results in rapid allergen uptake by dendritic cells through intact skin and downregulates the allergen-specific response in sensitized mice. J Immunol. 186, 5629-37 (2011).
    • (2011) J Immunol. , vol.186 , pp. 5629-5637
    • Dioszeghy, V.1
  • 26
    • 77958013242 scopus 로고    scopus 로고
    • Epicutaneous immunotherapy using a new epicutaneous delivery system in mice sensitized to peanuts
    • Mondoulet, L., et al. Epicutaneous immunotherapy using a new epicutaneous delivery system in mice sensitized to peanuts. Int Arch Allergy Immunol 154, 299-309 (2011).
    • (2011) Int Arch Allergy Immunol , vol.154 , pp. 299-309
    • Mondoulet, L.1
  • 27
    • 84901234714 scopus 로고    scopus 로고
    • The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long-term protection from eosinophilic disorders in peanut-sensitized mice
    • Dioszeghy, V., et al. The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long-term protection from eosinophilic disorders in peanut-sensitized mice. Clin Exp Allergy 44, 867-81 (2014).
    • (2014) Clin Exp Allergy , vol.44 , pp. 867-881
    • Dioszeghy, V.1
  • 28
    • 84894280387 scopus 로고    scopus 로고
    • Epicutaneous immune modulation with Bet v 1 plus R848 suppresses allergic asthma in a murine model
    • Siebeneicher, S., et al. Epicutaneous immune modulation with Bet v 1 plus R848 suppresses allergic asthma in a murine model. Allergy 69, 328-37 (2014).
    • (2014) Allergy , vol.69 , pp. 328-337
    • Siebeneicher, S.1
  • 29
    • 78650590515 scopus 로고    scopus 로고
    • Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer
    • Campana, R., et al. Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer. Mol Immunol 48, 431-41 (2011).
    • (2011) Mol Immunol , vol.48 , pp. 431-441
    • Campana, R.1
  • 30
    • 79951809149 scopus 로고    scopus 로고
    • Genetic engineering of trimers of hypoallergenic fragments of the major birch pollen allergen Bet v 1, for allergy vaccination
    • Vrtala, S., et al. Genetic engineering of trimers of hypoallergenic fragments of the major birch pollen allergen, Bet v 1, for allergy vaccination. Vaccine 29, 2140-48 (2011).
    • (2011) Vaccine , vol.29 , pp. 2140-2148
    • Vrtala, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.