Distinct PKC-mediated posttranscriptional events set cytokine production kinetics in CD8+ T cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 36, 2017, Pages 9677-9682

  Salerno, Fiamma ^a   Paolini, Nahuel A ^a   Stark, Regina ^a   Von Lindern, Marieke ^a   Wolkers, Monika C ^a  

^a SANQUIN RESEARCH   (Netherlands)

Author keywords

Cytokine production; MRNA stability; PKC; T cells; Translation efficiency

Indexed keywords

CALCIUM; GAMMA INTERFERON; INTERLEUKIN 2; IONOMYCIN; PROTEIN KINASE C; RAPAMYCIN; RUBOXISTAURIN; SOTRASTAURIN; TUMOR NECROSIS FACTOR; CYTOKINE; IFNG PROTEIN, MOUSE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE EXPRESSION; IMMUNOSTIMULATION; KINETICS; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PI3K/AKT SIGNALING; POLYSOME; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA TRANSLATION; T LYMPHOCYTE ACTIVATION; TRANSLATION INITIATION; ANIMAL; BIOSYNTHESIS; CALCIUM SIGNALING; ENZYMOLOGY; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; RNA PROCESSING; RNA STABILITY; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM SIGNALING; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; INTERFERON-GAMMA; INTERLEUKIN-2; KINETICS; LYMPHOCYTE ACTIVATION; MICE; PROTEIN BIOSYNTHESIS; PROTEIN KINASE C; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85029222724     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1704227114     Document Type: Article

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