-
1
-
-
70249100293
-
Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity
-
Sallusto F, Lanzavecchia A (2009) Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity. Eur J Immunol 39:2076-2082.
-
(2009)
Eur J Immunol
, vol.39
, pp. 2076-2082
-
-
Sallusto, F.1
Lanzavecchia, A.2
-
2
-
-
41149096579
-
T-cell quality in memory and protection: Implications for vaccine design
-
DOI 10.1038/nri2274, PII NRI2274
-
Seder RA, Darrah PA, Roederer M (2008) T-cell quality in memory and protection: Implications for vaccine design. Nat Rev Immunol 8:247-258. (Pubitemid 351432801)
-
(2008)
Nature Reviews Immunology
, vol.8
, Issue.4
, pp. 247-258
-
-
Seder, R.A.1
Darrah, P.A.2
Roederer, M.3
-
3
-
-
55949116720
-
Phenotype and function of human T lymphocyte subsets: Consensus and issues
-
Appay V, van Lier RAW, Sallusto F, Roederer M (2008) Phenotype and function of human T lymphocyte subsets: Consensus and issues. Cytometry A 73:975-983.
-
(2008)
Cytometry A
, vol.73
, pp. 975-983
-
-
Appay, V.1
Van Lier, R.A.W.2
Sallusto, F.3
Roederer, M.4
-
4
-
-
65549115862
-
Plasticity of CD4+ T cell lineage differentiation
-
Zhou L, Chong MMW, Littman DR (2009) Plasticity of CD4+ T cell lineage differentiation. Immunity 30:646-655.
-
(2009)
Immunity
, vol.30
, pp. 646-655
-
-
Zhou, L.1
Chong, M.M.W.2
Littman, D.R.3
-
5
-
-
33646686040
-
+ T cells
-
DOI 10.1182/blood-2005-12-4818
-
Betts MR, et al. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107:4781-4789. (Pubitemid 43882629)
-
(2006)
Blood
, vol.107
, Issue.12
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
De Rosa, S.C.4
Migueles, S.A.5
Abraham, J.6
Lederman, M.M.7
Benito, J.M.8
Goepfert, P.A.9
Connors, M.10
Roederer, M.11
Koup, R.A.12
-
6
-
-
42249096487
-
Polyfunctional T cell responses are a hallmark of HIV-2 infection
-
Duvall MG, et al. (2008) Polyfunctional T cell responses are a hallmark of HIV-2 infection. Eur J Immunol 38:350-363.
-
(2008)
Eur J Immunol
, vol.38
, pp. 350-363
-
-
Duvall, M.G.1
-
7
-
-
77956108181
-
Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection
-
Caccamo N, et al. (2010) Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection. Eur J Immunol 40:2211-2220.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2211-2220
-
-
Caccamo, N.1
-
8
-
-
34250327922
-
+ T cell responses
-
DOI 10.1084/jem.20062363
-
Precopio ML, et al. (2007) Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. J Exp Med 204:1405-1416. (Pubitemid 46919878)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.6
, pp. 1405-1416
-
-
Precopio, M.L.1
Betts, M.R.2
Parrino, J.3
Price, D.A.4
Gostick, E.5
Ambrozak, D.R.6
Asher, T.E.7
Douek, D.C.8
Harari, A.9
Pantaleo, G.10
Bailer, R.11
Graham, B.S.12
Roederer, M.13
Koup, R.A.14
-
9
-
-
34250303350
-
H1 cells define a correlate of vaccine-mediated protection against Leishmania major
-
DOI 10.1038/nm1592, PII NM1592
-
Darrah PA, et al. (2007) Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 13:843-850. (Pubitemid 47038186)
-
(2007)
Nature Medicine
, vol.13
, Issue.7
, pp. 843-850
-
-
Darrah, P.A.1
Patel, D.T.2
De Luca, P.M.3
Lindsay, R.W.B.4
Davey, D.F.5
Flynn, B.J.6
Hoff, S.T.7
Andersen, P.8
Reed, S.G.9
Morris, S.L.10
Roederer, M.11
Seder, R.A.12
-
10
-
-
67649216110
-
Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells
-
Lindenstrøm T, et al. (2009) Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells. J Immunol 182:8047-8055.
-
(2009)
J Immunol
, vol.182
, pp. 8047-8055
-
-
Lindenstrøm, T.1
-
11
-
-
33644909067
-
Cytokine detection by multiplex technology useful for assessing antigen specific cytokine profiles and kinetics in whole blood cultured up to seven days
-
Lagrelius M, Jones P, Franck K, Gaines H (2006) Cytokine detection by multiplex technology useful for assessing antigen specific cytokine profiles and kinetics in whole blood cultured up to seven days. Cytokine 33:156-165.
-
(2006)
Cytokine
, vol.33
, pp. 156-165
-
-
Lagrelius, M.1
Jones, P.2
Franck, K.3
Gaines, H.4
-
12
-
-
0033050060
-
Expression and kinetics of cytokines determined by intracellular staining using flow cytometry
-
DOI 10.1016/S0022-1759(98)00200-2, PII S0022175998002002
-
Mascher B, Schlenke P, Seyfarth M (1999) Expression and kinetics of cytokines determined by intracellular staining using flow cytometry. J Immunol Methods 223:115-121. (Pubitemid 29096243)
-
(1999)
Journal of Immunological Methods
, vol.223
, Issue.1
, pp. 115-121
-
-
Mascher, B.1
Schlenke, P.2
Seyfarth, M.3
-
13
-
-
0031567888
-
Visualization of Antigen-Specific T Cell Activation and Cytokine Expression in Vivo
-
Rogers WO, et al. (1997) Visualization of antigen-specific T cell activation and cytokine expression in vivo. J Immunol 158:649-657. (Pubitemid 127492642)
-
(1997)
Journal of Immunology
, vol.158
, Issue.2
, pp. 649-657
-
-
Rogers, W.O.1
Weaver, C.T.2
Kraus, L.A.3
Li, J.4
Li, L.5
Bucy, R.P.6
-
14
-
-
2442496266
-
+ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition
-
Sojka DK, Bruniquel D, Schwartz RH, Singh NJ (2004) IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition. J Immunol 172: 6136-6143. (Pubitemid 38621218)
-
(2004)
Journal of Immunology
, vol.172
, Issue.10
, pp. 6136-6143
-
-
Sojka, D.K.1
Bruniquel, D.2
Schwartz, R.H.3
Singh, N.J.4
-
16
-
-
59249091240
-
Multiplexed Elispot assay
-
Harriman WD, et al. (2009) Multiplexed Elispot assay. J Immunol Methods 341:127-134.
-
(2009)
J Immunol Methods
, vol.341
, pp. 127-134
-
-
Harriman, W.D.1
-
17
-
-
10744223436
-
A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokines
-
DOI 10.1016/j.jim.2003.08.013
-
Gazagne A, et al. (2003) A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokines. J Immunol Methods 283:91-98. (Pubitemid 37501061)
-
(2003)
Journal of Immunological Methods
, vol.283
, Issue.1-2
, pp. 91-98
-
-
Gazagne, A.1
Claret, E.2
Wijdenes, J.3
Yssel, H.4
Bousquet, F.5
Levy, E.6
Vielh, P.7
Scotte, F.8
Goupil, T.L.9
Fridman, W.H.10
Tartour, E.11
-
18
-
-
79958122357
-
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
-
Ma C, et al. (2011) A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nat Med 17:738-743.
-
(2011)
Nat Med
, vol.17
, pp. 738-743
-
-
Ma, C.1
-
19
-
-
33646380363
-
Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases
-
Pantaleo G, Harari A (2006) Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases. Nat Rev Immunol 6:417-423.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 417-423
-
-
Pantaleo, G.1
Harari, A.2
-
20
-
-
0024328679
-
Mechanisms of T cell activation by the calcium ionophore ionomycin
-
Chatila T, Silverman L, Miller R, Geha R (1989) Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol 143:1283-1289. (Pubitemid 19211362)
-
(1989)
Journal of Immunology
, vol.143
, Issue.4
, pp. 1283-1289
-
-
Chatila, T.1
Silverman, L.2
Miller, R.3
Geha, R.4
-
21
-
-
77952635983
-
Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving
-
Han Q, Bradshaw EM, Nilsson B, Hafler DA, Love JC (2010) Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving. Lab Chip 10:1391-1400.
-
(2010)
Lab Chip
, vol.10
, pp. 1391-1400
-
-
Han, Q.1
Bradshaw, E.M.2
Nilsson, B.3
Hafler, D.A.4
Love, J.C.5
-
22
-
-
0035400055
-
+ T lymphocytes
-
Sandberg JK, Fast NM, Nixon DF (2001) Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytes. J Immunol 167:181-187. (Pubitemid 32567776)
-
(2001)
Journal of Immunology
, vol.167
, Issue.1
, pp. 181-187
-
-
Sandberg, J.K.1
Fast, N.M.2
Nixon, D.F.3
-
23
-
-
50149090966
-
Variability and robustness in T cell activation from regulated heterogeneity in protein levels
-
Feinerman O, Veiga J, Dorfman JR, Germain RN, Altan-Bonnet G (2008) Variability and robustness in T cell activation from regulated heterogeneity in protein levels. Science 321:1081-1084.
-
(2008)
Science
, vol.321
, pp. 1081-1084
-
-
Feinerman, O.1
Veiga, J.2
Dorfman, J.R.3
Germain, R.N.4
Altan-Bonnet, G.5
-
24
-
-
41449097790
-
Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression
-
Podtschaske M, et al. (2007) Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression. PLoS ONE 2:e935.
-
(2007)
PLoS ONE
, vol.2
-
-
Podtschaske, M.1
-
25
-
-
49049117606
-
Biphasic regulation of Il2 transcription in CD4+ T cells: Roles for TNF-alpha receptor signaling and chromatin structure
-
McKarns SC, Schwartz RH (2008) Biphasic regulation of Il2 transcription in CD4+ T cells: Roles for TNF-alpha receptor signaling and chromatin structure. J Immunol 181:1272-1281.
-
(2008)
J Immunol
, vol.181
, pp. 1272-1281
-
-
McKarns, S.C.1
Schwartz, R.H.2
-
26
-
-
77951107351
-
Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression
-
Mariani L, et al. (2010) Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression. Molec Sys Biol 6:359.
-
(2010)
Molec Sys Biol
, vol.6
, pp. 359
-
-
Mariani, L.1
-
27
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, et al. (2000) A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100:655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
28
-
-
0030373901
-
The application of cluster analysis in strategic management research: An analysis and critique
-
Ketchen DJ, Shook CL (1996) The application of cluster analysis in strategic management research: An analysis and critique. Strateg Manage J 17:441-458.
-
(1996)
Strateg Manage J
, vol.17
, pp. 441-458
-
-
Ketchen, D.J.1
Shook, C.L.2
-
29
-
-
0036225712
-
T-cell antigen receptor signal transduction
-
Cantrell DA (2002) T-cell antigen receptor signal transduction. Immunology 105:369-374.
-
(2002)
Immunology
, vol.105
, pp. 369-374
-
-
Cantrell, D.A.1
-
30
-
-
58249092059
-
Digital signaling and hysteresis characterize ras activation in lymphoid cells
-
Das J, et al. (2009) Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell 136:337-351.
-
(2009)
Cell
, vol.136
, pp. 337-351
-
-
Das, J.1
-
31
-
-
39449094869
-
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation
-
DOI 10.1038/ni1559, PII NI1559
-
Henrickson SE, et al. (2008) T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat Immunol 9:282-291. (Pubitemid 351267325)
-
(2008)
Nature Immunology
, vol.9
, Issue.3
, pp. 282-291
-
-
Henrickson, S.E.1
Mempel, T.R.2
Mazo, I.B.3
Liu, B.4
Artyomov, M.N.5
Zheng, H.6
Peixoto, A.7
Flynn, M.P.8
Senman, B.9
Junt, T.10
Wong, H.C.11
Chakraborty, A.K.12
Von, A.U.H.13
-
32
-
-
33745470929
-
Robustness trade-offs and host-microbial symbiosis in the immune system
-
Kitano H, Oda K (2006) Robustness trade-offs and host-microbial symbiosis in the immune system. Mol Syst Biol, 2006.0022.
-
(2006)
Mol Syst Biol
, vol.2006
, pp. 0022
-
-
Kitano, H.1
Oda, K.2
-
33
-
-
58049203835
-
Systems biology of innate immunity
-
Zak DE, Aderem A (2009) Systems biology of innate immunity. Immunol Rev 227:264-282.
-
(2009)
Immunol Rev
, vol.227
, pp. 264-282
-
-
Zak, D.E.1
Aderem, A.2
-
34
-
-
41349119880
-
Stochastic switching as a survival strategy in fluctuating environments
-
DOI 10.1038/ng.110, PII NG110
-
Acar M, Mettetal JT, van Oudenaarden A (2008) Stochastic switching as a survival strategy in fluctuating environments. Nat Genet 40:471-475. (Pubitemid 351450880)
-
(2008)
Nature Genetics
, vol.40
, Issue.4
, pp. 471-475
-
-
Acar, M.1
Mettetal, J.T.2
Van Oudenaarden, A.3
-
35
-
-
4644343922
-
Bacterial persistence as a phenotypic switch
-
DOI 10.1126/science.1099390
-
Balaban NQ, Merrin J, Chait R, Kowalik L, Leibler S (2004) Bacterial persistence as a phenotypic switch. Science 305:1622-1625. (Pubitemid 39296357)
-
(2004)
Science
, vol.305
, Issue.5690
, pp. 1622-1625
-
-
Balaban, N.Q.1
Merrin, J.2
Chait, R.3
Kowalik, L.4
Leibler, S.5
-
36
-
-
45149086183
-
Nongenetic individuality in the host-phage interaction
-
Pearl S, Gabay C, Kishony R, Oppenheim A, Balaban NQ (2008) Nongenetic individuality in the host-phage interaction. PLoS Biol 6:e120.
-
(2008)
PLoS Biol
, vol.6
-
-
Pearl, S.1
Gabay, C.2
Kishony, R.3
Oppenheim, A.4
Balaban, N.Q.5
-
37
-
-
73849110167
-
Heterogeneity and plasticity of T helper cells
-
Zhu J, Paul WE (2010) Heterogeneity and plasticity of T helper cells. Cell Res 20:4-12.
-
(2010)
Cell Res
, vol.20
, pp. 4-12
-
-
Zhu, J.1
Paul, W.E.2
-
38
-
-
77649242104
-
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
-
Busse D, et al. (2010) Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proc Natl Acad Sci USA 107:3058-3063.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3058-3063
-
-
Busse, D.1
-
39
-
-
78649875958
-
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response
-
Feinerman O, et al. (2010) Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response. Mol Syst Biol 6:437.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 437
-
-
Feinerman, O.1
|