Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death

Science

Volumn 357, Issue 6355, 2017, Pages 1037-1041

  Shlezinger, Neta ^a   Irmer, Henriette ^b   Dhingra, Sourabh ^c   Beattie, Sarah R ^c   Cramer, Robert A ^c   Braus, Gerhard H ^b   Sharon, Amir ^d   Hohl, Tobias M ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AFBIR1 PROTEIN; CASPASE 3; CASPASE 7; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; DOUBLE STRANDED DNA; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FUNGAL PROTEIN; HISTONE H2A; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; RED FLUORESCENT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SURVIVIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; N-NITROSOALLYL-2,3-DIHYDROXYPROPYLAMINE; NITROSAMINE;

APOPTOSIS; CELLS AND CELL COMPONENTS; FUNGUS; GENE EXPRESSION; GENETIC ANALYSIS; GERMINATION; IMMUNE RESPONSE; IMMUNITY; PHYSIOLOGY;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASPERGILLUS FUMIGATUS; CELL KILLING; CONIDIUM; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; FLUORESCENCE IMAGING; FUNGAL CELL; GENETIC ANALYSIS; GERMINATION; HOST SUSCEPTIBILITY; HUMAN; HUMAN CELL; IMMUNITY; IMMUNOSURVEILLANCE; INSTRUMENT STERILIZATION; LUNG; LUNG ASPERGILLOSIS; LUNG CLEARANCE; MOULD; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BONE MARROW CELL; FUNGUS SPORE; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MOUSE;

ASPERGILLUS FUMIGATUS; MURINAE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ASPERGILLUS FUMIGATUS; FUNGAL PROTEINS; IMMUNOLOGIC SURVEILLANCE; LUNG; MICE; MYELOID CELLS; NADPH OXIDASES; NEUTROPHILS; NITROSAMINES; PULMONARY ASPERGILLOSIS; SPORES, FUNGAL;

EID: 85029209355     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aan0365     Document Type: Article

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