Treating breathlessness via the brain: Changes in brain activity over a course of pulmonary rehabilitation

European Respiratory Journal

Volumn 50, Issue 3, 2017, Pages

  Herigstad, Mari ^a,b   Faull, Olivia K ^a   Hayen, Anja ^a,c   Evans, Eleanor ^a   Hardinge, F Maxine ^d   Wiech, Katja ^a   Pattinson, Kyle T S ^a,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF READING   (United Kingdom)

^d OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANXIETY; ARTICLE; ATTENTION; BRAIN FUNCTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE SEVERITY; DYSPNEA; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MALE; NERVE POTENTIAL; PERCEPTION; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; PULMONARY REHABILITATION; BEHAVIOR ASSESSMENT; BRAIN CORTEX; CASE CONTROL STUDY; DIAGNOSTIC IMAGING; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PSYCHOLOGY; SELF REPORT; VISUAL ANALOG SCALE;

AGED; ANXIETY; BEHAVIOR RATING SCALE; CASE-CONTROL STUDIES; CEREBRAL CORTEX; DYSPNEA; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SELF REPORT; VISUAL ANALOG SCALE;

EID: 85029155786     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/13993003.01029-2017     Document Type: Article

References (44)

1. Carel H. Illness: The Cry of the Flesh. Stocksfield, Acumen, 2008.
2. Hayen A, Herigstad M, Pattinson KT. Understanding dyspnea as a complex individual experience. Maturitas 2013; 76: 45-50.
3. Parshall MB, Schwartzstein RM, Adams L, et al. An official American Thoracic Society statement: Update on the mechanisms, assessment, and management of dyspnea. Am J Respir Crit Care Med 2012; 185: 435-452.
4. McCarthy B, Casey D, Devane D, et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2015; 2: CD003793.
5. Carrieri-Kohlman V, Donesky-Cuenco D, Park SK, et al. Additional evidence for the affective dimension of dyspnea in patients with COPD. Res Nurs Health 2010; 33: 4-19.
6. National COPD Audit Programme. Pulmonary rehabilitation: Steps to breathe better. National Chronic Obstructive Pulmonary Disease (COPD) Audit Programme: Clinical audit of pulmonary rehabilitation services in England and Wales 2015. 2016. www.rcplondon.ac.uk/projects/outputs/pulmonary-rehabilitation-steps-breathebetter Date last accessed: July 21, 2017.
7. Van den Bergh O, Witthoft M, Petersen S, et al. Symptoms and the body: Taking the inferential leap. Neurosci Biobehav Rev 2017; 74: 185-203.
8. Lansing RW, Gracely RH, Banzett RB. The multiple dimensions of dyspnea: Review and hypotheses. Respir Physiol Neurobiol 2009; 167: 53-60.
9. Barrett LF, Simmons WK. Interoceptive predictions in the brain. Nat Rev Neurosci 2015; 16: 419-429.
10. Faull OK, Jenkinson M, Ezra M, et al. Conditioned respiratory threat in the subdivisions of the human periaqueductal gray. Elife 2016; 5: E12047.
11. Faull OK, Pattinson KT. The cortical connectivity of the periaqueductal gray and the conditioned response to the threat of breathlessness. Elife 2017; 6: E21749.
12. Pappens M, Vandenbossche E, Van den Bergh O, et al. Interoceptive fear learning to mild breathlessness as a laboratory model for unexpected panic attacks. Front Psychol 2015; 6: 1150.
13. Van Diest I, De Peuter S, Piedfort K, et al. Acquired lightheadedness in response to odors after hyperventilation. Psychosom Med 2006; 68: 340-347.
14. Hayen A, Wanigasekera V, Faull OK, et al. Opioid suppression of conditioned anticipatory brain responses to breathlessness. Neuroimage 2017; 150: 383-394.
15. Faull OK, Hayen A, Pattinson KTS. Breathlessness and the body: neuroimaging clues for the inferential leap. Cortex 2017; in press. [https://doi.org/10.1016/j.cortex.2017.07.019]
16. Stoeckel MC, Esser RW, Gamer M, et al. Brain responses during the anticipation of dyspnea. Neural Plast 2016; 2016: 6434987.
17. von Leupoldt A, Kenn K. The psychology of chronic obstructive pulmonary disease. Curr Opin Psychiatry 2013; 26: 458-463.
18. Carrieri-Kohlman V, Gormley JM, Eiser S, et al. Dyspnea and the affective response during exercise training in obstructive pulmonary disease. Nurs Res 2001; 50: 136-146.
19. Wadell K, Webb KA, Preston ME, et al. Impact of pulmonary rehabilitation on the major dimensions of dyspnea in COPD. COPD 2013; 10: 425-435.
20. Herigstad M, Hayen A, Reinecke A, et al. Development of a dyspnoea word cue set for studies of emotional processing in COPD. Respir Physiol Neurobiol 2016; 223: 37-42.
21. Herigstad M, Hayen A, Evans E, et al. Dyspnea-related cues engage the prefrontal cortex: Evidence from functional brain imaging in COPD. Chest 2015; 148: 953-961.
22. Radloff L. A self-report depression scale for research in the general population. Appl Psychol Meas 1977; 1: 385-401.
23. Spielberger CD, Gorsuch RL, Lushene R, et al. Manual for the State-Trait Anxiety Inventory. Palo Alto, Consulting Psychologists Press, 1989.
24. Krupp LB, LaRocca NG, Muir-Nash J, et al. The Fatigue Severity Scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 1989; 46: 1121-1123.
25. Jones PW, Quirk FH, Baveystock CM, et al. A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire. Am Rev Respir Dis 1992; 145: 1321-1327.
26. Bestall JC, Paul EA, Garrod R, et al. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax 1999; 54: 581-586.
27. Yorke J, Moosavi SH, Shuldham C, et al. Quantification of dyspnoea using descriptors: Development and initial testing of the Dyspnoea-12. Thorax 2010; 65: 21-26.
28. De Peuter S, Lemaigre V, Van Diest I, et al. Illness-specific catastrophic thinking and overperception in asthma. Health Psychol 2008; 27: 93-99.
29. McCracken LM. "Attention" to pain in persons with chronic pain: A behavioral approach. Behav Ther 1997; 28: 271-284.
30. Carver CS, White TL. Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: The BIS/BAS scales. J Pers Soc Psychol 1994; 67: 319-333.
31. Levy ML, Quanjer PH, Booker R, et al. Diagnostic spirometry in primary care: Proposed standards for general practice compliant with American Thoracic Society and European Respiratory Society recommendations: A General Practice Airways Group (GPIAG) document, in association with the Association for Respiratory Technology & Physiology (ARTP) and Education for Health. Prim Care Respir J 2009; 18: 130-147.
32. Wager TD, Davidson ML, Hughes BL, et al. Prefrontal-subcortical pathways mediating successful emotion regulation. Neuron 2008; 59: 1037-1050.
33. Worsley KJ, Evans AC, Marrett S, et al. A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab 1992; 12: 900-918.
34. Jones PW. St. George's Respiratory Questionnaire: MCID. COPD 2005; 2: 75-79.
35. Parreira VF, Janaudis-Ferreira T, Evans RA, et al. Measurement properties of the incremental shuttle walk test. A systematic review. Chest 2014; 145: 1357-1369.
36. Yorke J, Lloyd-Williams M, Smith J, et al. Management of the respiratory distress symptom cluster in lung cancer: A randomised controlled feasibility trial. Support Care Cancer 2015; 23: 3373-3384.
37. Scioscia G, Blanco I, Arismendi E, et al. Different dyspnoea perception in COPD patients with frequent and infrequent exacerbations. Thorax 2017; 72: 117-121.
38. Leech R, Sharp DJ. The role of the posterior cingulate cortex in cognition and disease. Brain 2014; 137: 12-32.
39. Yang Y, Lueken U, Wittmann A, et al. Neural correlates of individual differences in anxiety sensitivity: An fMRI study using semantic priming. Soc Cogn Affect Neurosci 2016; 11: 1245-1254.
40. Goldin PR, Manber T, Hakimi S, et al. Neural bases of social anxiety disorder: Emotional reactivity and cognitive regulation during social and physical threat. Arch Gen Psychiatry 2009; 66: 170-180.
41. Hayen A, Herigstad M, Kelly M, et al. The effects of altered intrathoracic pressure on resting cerebral blood flow and its response to visual stimulation. Neuroimage 2012; 66C: 479-488.
42. Janssens T, De Peuter S, Stans L, et al. Dyspnea perception in COPD: Association between anxiety, dyspnea-related fear, and dyspnea in a pulmonary rehabilitation program. Chest 2011; 140: 618-625.
43. Singewald N, Schmuckermair C, Whittle N, et al. Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacol Ther 2015; 149: 150-190.
44. Borge CR, Hagen KB, Mengshoel AM, et al. Effects of controlled breathing exercises and respiratory muscle training in people with chronic obstructive pulmonary disease: Results from evaluating the quality of evidence in systematic reviews. BMC Pulm Med 2014; 14: 184.