Management of the respiratory distress symptom cluster in lung cancer: a randomised controlled feasibility trial

Supportive Care in Cancer

Volumn 23, Issue 11, 2015, Pages 3373-3384

  Yorke, Janelle ^a,b   Lloyd Williams, Mari ^c   Smith, Jacky ^d,e   Blackhall, Fiona ^b,e   Harle, Amelie ^b   Warden, June ^a   Ellis, Jackie ^c   Pilling, Mark ^a   Haines, Jemma ^f   Luker, Karen ^a   Molassiotis, Alex ^a,g  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f LANCASHIRE TEACHING HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^g HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Breathlessness; Cough; Dyspnoea; Fatigue; Lung cancer; Non pharmacological intervention; Respiratory symptoms; Self management; Symptom cluster; Symptoms

Indexed keywords

ANTINEOPLASTIC AGENT;

AGED; ARTICLE; CANCER FATIGUE; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CONTROLLED STUDY; COUGHING; DISEASE SEVERITY; DYSPNEA; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RESPIRATORY DISTRESS SYNDROME; SAMPLE SIZE; TELEPHONE; ACUPRESSURE; BREATHING EXERCISE; CLINICAL TRIAL; COMPLICATION; COUGH; FATIGUE; LUNG TUMOR; PATIENT EDUCATION; PROCEDURES; SYNDROME;

ACUPRESSURE; AGED; BREATHING EXERCISES; COUGH; DYSPNEA; FATIGUE; FEASIBILITY STUDIES; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; PATIENT EDUCATION AS TOPIC; SYNDROME;

EID: 84942500064     PISSN: 09414355     EISSN: 14337339     Source Type: Journal    
DOI: 10.1007/s00520-015-2810-x     Document Type: Article

References (42)

1. Molassiotis A, Lowe M, Blackhall F, Lorigan P (2011) A qualitative exploration of a respiratory distress symptom cluster in lung cancer: cough, breathlessness and fatigue. Lung Cancer 71(1):94–102
2. Cheville AL, Novotny PJ, Sloan JA, Basford JR, Wampfler JA, Garces YI, Jatoi A, Yang P (2011) Fatigue, dyspnea, and cough comprise a persistent symptom cluster up to five years after diagnosis with lung cancer. J Pain Symptom Manag 42(2):202–12
3. Edmonds P, Higginson I, Altmann D, Sen-Gupta G, McDonnell M (2000) Is the presence of dyspnea a risk factor for morbidity in cancer patients? J Pain Symptom Manag 19(1):15–22
4. Molassiotis A, Lowe M, Ellis J, Wagland R, Bailey C, Lloyd-Williams M, Tishelman C, Smith J (2011) The experience of cough in patients diagnosed with lung cancer. Support Care Cancer 19(12):1997–2004
5. Hofman M, Ryan JL, Figueroa-Mosele CD, Jean-Pierre P, Morrow GR (2007) Cancer related fatigue: the scale of the problem. Oncologist 12(Suppl 1):4–10
6. Dodd MJ, Miaskowski C, Paul SM (2001) Symptom clusters and their effect on the functional status of patients with cancer. Oncol Nurs Forum 28(3):465–470
7. Molassiotis A, Uyterlinde W, Hollen PJ, Sarna L, Palmer P, Krishnasamy M (2015) Supportive care in lung cancer: milestones over the past 40 years. J Thorac Oncol 10(1):10–18
8. Yorke J, Brettle A, Molassiotis A (2012) 12. Nonpharmacological interventions for managing respiratory symptoms in lung cancer. Chron Respir Dis 9(2):117–29
9. Bausewein C, Booth S, Gysels M, Higginson I (2008) Non-pharmacological interventions for breathlessness in advances stages of malignant and non-malignant disease. Cochrane Database Syst Rev 2, CD005623
10. Farquhar MC, Prevost AB, McCrone P, Brafman-Price B, Bentley A, Higginson IJ, Todd C, Booth S (2014) Is a specialist breathlessness service more effective and cost effective for patients with advanced cancer and their carers than standard care? Findings of a mixed-method randomised controlled trial. BMC Med 12:194
11. Zick SM, Alrawi S, Merel G, Burris B, Sen A, Litzinger A, Harris RE (2011) Relaxation acupressure reduces persistent cancer-related fatigue. Evidence-based Complemen Altern Med; Article ID 142913, 10 pages
12. Molassiotis A, Sylt P, Diggins H (2007) The management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomized controlled trial. Complement Ther Med 15(4):228–237
13. Vickers AJ, Straus DJ, Fearon B, Cassileth BR (2004) Acupuncture for post chemotherapy fatigue: a phase II study. J Clin Oncol 22(9):1731–1735
14. Chamberlain S, Birring SS, Garrod R (2014) Non-pharmacological interventions for refractory chronic cough patients: systematic review. Lung 192:75–85
15. Vertigan AE, Theodoros DG, Gibson PG, Winkworth AL (2006) Efficacy of speech pathology management for chronic cough: a randomised placebo controlled. Thorax 61:1065–69
16. Medical Research Council (2000) A framework for development and evaluation of RCTSs for complex interventions to improve health. London
17. Ellis J, Wagland R, Tishelman C, Williams ML, Bailey CD, Haines J, Caress AC, Lorigan P, Smith JA, Booton R, Blackhall F, Molassiotis A (2012) Considerations in developing and delivering a non-pharmacological intervention for symptom management in lung cancer: the views of patients and informal caregivers. J Pain Symptom Manag 44(6):831–42
18. Wagland R, Ellis J, Bailey CD, Haines J, Caress A, Williams ML, Lorigan P, Smith J, Tishelman C, Booton R, Luker K, Blackhall F, Molassiotis A (2012) Considerations in developing and delivering a non-pharmacological intervention for symptom management in lung cancer: the views of health care professionals. Support Care Cancer 20(10):2565–74
19. Molassiotis A, Emsley R, Ashcroft D, Caress AC, Ellis J, Wagland R, Bailey CD, Haines J, Williams ML, Lorigan P, Smith J, Tishelman C, Blackhall F (2012) Applying Best-Worst scaling methodology to establish delivery preferences of a symptom supportive care intervention in patients with lung cancer. Lung Cancer 77(1):199–204
20. Barton R, English A, Nabb S, Rigby AS, Johnson MJ (2010) A randomised trial of high vs low intensity training in breathing techniques for breathless patients with malignant lung disease: a feasibility study. Lung Cancer 70(3):313–9
21. Yorke J, Moosavi SH, Shuldham C, Jones PW (2010) Quantification of dyspnoea using descriptors: development and initial testing of the Dyspnoea-12. Thorax 65(1):21–6
22. Yorke J, Armstrong I (2013) Assessment of breathlessness in pulmonary hypertension: validation of the Dyspnoea-12. Eur J Cardiovasc Nurs 13(6):506–14
23. Yorke J, Swigris J, Russell AM, Kwong G, Jones PW (2013) Dyspnoea-12 is a valid and reliable measure of breathlessness in patients with interstitial lung disease. Chest 139(1):159–164
24. Molassiotis A, Ellis J, Wagland R, Lloyd Williams M, Blackhall F, Yorke J, Smith JE (2012) The Manchester Cough in Lung Cancer scale: the development and validation of a new assessment tool. J Pain Symptom Manag 45(2):179–90
25. Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan E (1997) Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system. J Pain Symptom Manag 13(2):63–74
26. Hollen PJ, Gralla RJ, Kris MG, Cox C, Belani CP, Grunberg SM, Crawford J, Neidhart JA (1994) Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies: psychometric assessment of the Lung Cancer Symptom Scale. Cancer 73:2087–2098
27. EuroQoL Group (1990) EuroQoL: a new facility for the measurement of health-related quality of life. Health Policy 16:199–208
28. Kind P, Hardman G, Macran S (1999) UK population norms for EQ-5D. York Centre for Health Economics, Discussion Paper, University of York
29. Zigmond AS, Snaith PR (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361–370
30. Lancaster GA, Dodd S, Williamson PR (2004) Design and analysis of pilot studies: recommendations for good practice. J Eval Clin Pract 10(2):307–12
31. Liang KY, Zeger SL (1986) Longitudinal data analysis using generalized linear models. Biometrika 73:13(22)
32. Twisk JWR (2003) Applied longitudinal data analysis for epidemiology: a practical guide. Cambridge University Press
33. Oxberry SG, Bland MJ, Clark AL, Cleland JGF, Johnson M (2012) Minimally clinically important difference in chronic breathlessness: every little helps. Am Heart J 164(2):229–35
34. de Kleijn WP, De Vries J, Wijnen PA, Drent M (2011) Minimal (clinically) important differences for the Fatigue Assessment Scale in sarcoidosis. Respir Med 105:1388–1395
35. Johnson MJ, Bland JM, Oxberry SG, Abernethy AP, Currow DC (2013) Clinically important differences in the intensity of chronic refractory breathlessness. J Pain Symptom Manag 46(6):957–63
36. Pouchot J, Kherani RB, Brant R, Lacaille D et al (2008) Determination of the minimally important difference for seven fatigue scales in rheumatoid arthritis. J Clin Epidemiol 61(7):705–713
37. Borm GF, Fransen J, Lemmens WA (2007) A simple sample size formula for analysis of covariance in randomised clinical trials. J Clin Epidemiol 60(12):1234–1238
38. Yost KJ, Eton DT (2005) Combining distribution and anchor-based approaches to determine minimal clinical differences: the FACIT experience. Eval Health Prof 28(2):172–191
39. Speck RM, Courneya KS, Masse LC, Duval S, Schmitz KH (2012) An update on controlled physical activity trials in cancer survivors: a systematic review and meta-analysis. J Cancer Surviv 4:87–100
40. Schwartz AL, Mori M, Gao R, Nail LM, King M (2001) Exercise reduces daily fatigue in women with breast cancer receiving chemotherapy. Med Sci Sports Exerc 33(5):718–723
41. Chan CWH, Richardson A, Richardson J (2011) Managing symptoms in patients with advanced lung cancer during radiotherapy: results of a psychoeducational randomised controlled trial. J Pain Symptom Manag 41(2):346–348
42. Brazier J, Ratcliffe J, Salomon JA, Tsuchiya A (2007) Measuring and valuing health benefits for economic evaluation. Oxford University Press, Oxford