Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation

Oncotarget

Volumn 8, Issue 34, 2017, Pages 56460-56472

  Boudot, Cédric ^a   Hénaut, Lucie ^a   Thiem, Ursula ^a   Geraci, Sandra ^b   Galante, Mariangela ^a   Saldanha, Paulo ^a   Saidak, Zuzana ^a   Six, Isabelle ^a   Clézardin, Philippe ^b   Kamel, Said ^a   Mentaverri, Romuald ^a  

^a INSERM   (France)

^b University of Lyon Claude Bernard   (France)

Author keywords

Bone metastasis; Breast cancer; Calcium sensing receptor; Epiregulin; Osteolysis

Indexed keywords

CALCIUM SENSING RECEPTOR; EPIREGULIN; MESSENGER RNA; NEUTRALIZING ANTIBODY; OSTEOPROTEGERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE METASTASIS; BREAST CANCER; CANCER CELL; CASR GENE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MDA-MB-231 CELL LINE; MOUSE; NONHUMAN; OPG GENE; OSTEOBLAST; OSTEOLYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TARGETING;

EID: 85029096145     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.16999     Document Type: Article

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