Hemolytic potential of tafenoquine in female volunteers heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal volunteers

American Journal of Tropical Medicine and Hygiene

Volumn 97, Issue 3, 2017, Pages 702-711

  Rueangweerayut, Ronnatrai ^a   Bancone, Germana ^b   Harrell, Emma J ^c   Beelen, Andrew P ^d   Kongpatanakul, Supornchai ^e   Möhrle, Jörg J ^f   Rousell, Vicki ^c   Mohamed, Khadeeja ^c   Qureshi, Ammar ^c   Narayan, Sushma ^c   Yubon, Nushara ^c   Miller, Ann ^d   Nosten, François H ^b   Luzzatto, Lucio ^g,h   Duparc, Stephan ^f   Kleim, Jörg Peter ^c   Green, Justin A ^c  

^a MAE SOT GENERAL HOSPITAL   (Thailand)

^b SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^c GLAXOSMITHKLINE   (United Kingdom)

^d GLAXOSMITHKLINE   (United States)

^e MAHIDOL UNIVERSITY   (Thailand)

^f Medicines for Malaria Venture   (Switzerland)

^g ISTITUTO TOSCANO TUMORI   (Italy)

^h MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEMOGLOBIN; METHEMOGLOBIN; PRIMAQUINE; TAFENOQUINE; AMINOQUINOLINE DERIVATIVE; ANTIMALARIAL AGENT;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HEMOLYSIS; HEMOLYTIC ANEMIA; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; OPEN STUDY; OUTCOMES RESEARCH; PHASE 3 CLINICAL TRIAL (TOPIC); PLASMODIUM VIVAX MALARIA; RELAPSE; RISK ASSESSMENT; SINGLE DRUG DOSE; ADOLESCENT; CASE CONTROL STUDY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; AMINOQUINOLINES; ANTIMALARIALS; CASE-CONTROL STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; HETEROZYGOTE; HUMANS; MIDDLE AGED; YOUNG ADULT;

EID: 85028988711     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.16-0779     Document Type: Article

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